DPYL4_HUMAN
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration . [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in DPYL4_HUMAN |
---|---|---|---|---|
GO:0031005 | filamin binding | 13.0435 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in DPYL4_HUMAN |
---|---|---|---|---|
GO:0051128 | regulation of cellular component organization | 47.8261 | 4 | no |
GO:0048523 | negative regulation of cellular process | 47.8261 | 4 | no |
GO:0048522 | positive regulation of cellular process | 47.8261 | 4 | no |
GO:0030030 | cell projection organization | 43.4783 | 4 | yes |
GO:0031175 | neuron projection development | 43.4783 | 6 | yes |
GO:0120036 | plasma membrane bounded cell projection organization | 43.4783 | 5 | yes |
GO:0045595 | regulation of cell differentiation | 39.1304 | 4 | no |
GO:0009966 | regulation of signal transduction | 39.1304 | 4 | no |
GO:0010646 | regulation of cell communication | 39.1304 | 4 | no |
GO:0097485 | neuron projection guidance | 30.4348 | 7 | yes |
GO:0048585 | negative regulation of response to stimulus | 30.4348 | 4 | no |
GO:0051049 | regulation of transport | 30.4348 | 4 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 26.0870 | 6 | no |
GO:0007411 | axon guidance | 26.0870 | 8 | no |
GO:0009968 | negative regulation of signal transduction | 26.0870 | 5 | no |
GO:0010468 | regulation of gene expression | 26.0870 | 5 | no |
GO:0010648 | negative regulation of cell communication | 26.0870 | 5 | no |
GO:0023057 | negative regulation of signaling | 26.0870 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 26.0870 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 26.0870 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 26.0870 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 26.0870 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 26.0870 | 5 | no |
GO:0051094 | positive regulation of developmental process | 26.0870 | 4 | no |
GO:0071310 | cellular response to organic substance | 26.0870 | 4 | no |
GO:0031344 | regulation of cell projection organization | 26.0870 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 21.7391 | 4 | no |
GO:0051129 | negative regulation of cellular component organization | 21.7391 | 5 | no |
GO:0051241 | negative regulation of multicellular organismal process | 21.7391 | 4 | no |
GO:0043933 | protein-containing complex organization | 21.7391 | 4 | no |
GO:0045597 | positive regulation of cell differentiation | 21.7391 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 21.7391 | 5 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 21.7391 | 4 | no |
GO:0010975 | regulation of neuron projection development | 21.7391 | 7 | no |
GO:0022607 | cellular component assembly | 21.7391 | 4 | no |
GO:0007399 | nervous system development | 17.3913 | 4 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
TFCP2_HUMAN | [view interactions] | High throughput | no | no |
ATPF2_HUMAN | [view interactions] | High throughput | no | yes |
SYJ2B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOQ_HUMAN | [view interactions] | High throughput | no | no |
ACTC_HUMAN | [view interactions] | High throughput | no | no |
BICD2_HUMAN | [view interactions] | High throughput | no | yes |
TTP_HUMAN | [view interactions] | High throughput | no | yes |
TBB5_HUMAN | [view interactions] | High throughput | no | yes |
NAA40_HUMAN | [view interactions] | High throughput | no | no |
DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTPRO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SH3G1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SH3G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NOE2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DPYL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KLDC3_HUMAN | [view interactions] | High throughput | no | yes |
DPYL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SKP2_HUMAN | [view interactions] | High throughput | no | yes |
LEG7_HUMAN | [view interactions] | High throughput | no | no |
CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MET_HUMAN | [view interactions] | High throughput | no | yes |
PCH2_HUMAN | [view interactions] | High throughput | no | no |
RBPMS_HUMAN | [view interactions] | High throughput | no | no |
KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TGFR2_HUMAN | [view interactions] | High throughput | no | no |
WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPRE1_HUMAN | [view interactions] | High throughput | no | yes |
SH3G3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TRI54_HUMAN | [view interactions] | High throughput | no | no |
TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HAX1_HUMAN | [view interactions] | High throughput | no | no |
NUFP1_HUMAN | [view interactions] | High throughput | no | yes |
DGUOK_HUMAN | [view interactions] | High throughput | no | yes |
KTU_HUMAN | [view interactions] | High throughput | no | yes |
RHG25_HUMAN | [view interactions] | High throughput | no | no |
LIPH_HUMAN | [view interactions] | High throughput | no | no |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
DOCK5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LYPD4_HUMAN | [view interactions] | High throughput | no | no |
DEFI8_HUMAN | [view interactions] | High throughput | no | yes |
WDFY3_HUMAN | [view interactions] | High throughput | no | yes |
UBP47_HUMAN | [view interactions] | High throughput | no | yes |
UBIP1_HUMAN | [view interactions] | High throughput | no | no |
KLHL8_HUMAN | [view interactions] | High throughput | no | no |
M4K2_HUMAN | [view interactions] | High throughput | no | yes |
CTG1B_HUMAN | [view interactions] | High throughput | no | no |
PLCG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DPYS_HUMAN | [view interactions] | High throughput | no | no |
DPYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CBWD3_HUMAN | [view interactions] | High throughput | no | yes |
PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S10A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MMAB_HUMAN | [view interactions] | High throughput | no | yes |
FA9_HUMAN | [view interactions] | High throughput | no | no |
GSK3B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |