SH3G1_HUMAN
Evidence for PS localization
Functions
Implicated in endocytosis. May recruit other proteins to membranes with high curvature . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SH3G1_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 25.6757 | 4 | no |
| GO:0000166 | nucleotide binding | 22.9730 | 4 | no |
| GO:0017076 | purine nucleotide binding | 22.9730 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 22.9730 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.9730 | 4 | no |
| GO:0043168 | anion binding | 22.9730 | 4 | no |
| GO:0019901 | protein kinase binding | 22.9730 | 5 | no |
| GO:0043169 | cation binding | 21.6216 | 4 | no |
| GO:0046872 | metal ion binding | 20.2703 | 5 | no |
| GO:0045296 | cadherin binding | 16.2162 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SH3G1_HUMAN |
|---|---|---|---|---|
| GO:0051128 | regulation of cellular component organization | 59.4595 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 58.1081 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 51.3514 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 47.2973 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 45.9459 | 4 | no |
| GO:0010646 | regulation of cell communication | 44.5946 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 40.5405 | 4 | no |
| GO:0009966 | regulation of signal transduction | 36.4865 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 35.1351 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 35.1351 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 35.1351 | 5 | no |
| GO:0051049 | regulation of transport | 35.1351 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 33.7838 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.7838 | 6 | no |
| GO:0022607 | cellular component assembly | 33.7838 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 32.4324 | 5 | no |
| GO:0006996 | organelle organization | 31.0811 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 31.0811 | 5 | no |
| GO:0008104 | protein localization | 31.0811 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.7297 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 29.7297 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 28.3784 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 27.0270 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 27.0270 | 4 | no |
| GO:0060341 | regulation of cellular localization | 25.6757 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 25.6757 | 5 | no |
| GO:0043933 | protein-containing complex organization | 24.3243 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.3243 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 24.3243 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 24.3243 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.3243 | 6 | no |
| GO:0023056 | positive regulation of signaling | 24.3243 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.3243 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.3243 | 5 | no |
| GO:0030030 | cell projection organization | 22.9730 | 4 | no |
| GO:0032880 | regulation of protein localization | 22.9730 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 21.6216 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 21.6216 | 6 | no |
| GO:0097435 | supramolecular fiber organization | 21.6216 | 4 | no |
| GO:0033043 | regulation of organelle organization | 21.6216 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 21.6216 | 7 | no |
| GO:0031399 | regulation of protein modification process | 21.6216 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 21.6216 | 7 | no |
| GO:0051050 | positive regulation of transport | 21.6216 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.2703 | 6 | no |
| GO:0031344 | regulation of cell projection organization | 20.2703 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 20.2703 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.2703 | 6 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 20.2703 | 5 | no |
| GO:0071702 | organic substance transport | 20.2703 | 4 | no |
| GO:0022411 | cellular component disassembly | 13.5135 | 4 | yes |
| GO:0032984 | protein-containing complex disassembly | 9.4595 | 5 | yes |
| GO:0051261 | protein depolymerization | 9.4595 | 6 | yes |
| GO:0007417 | central nervous system development | 8.1081 | 4 | yes |
| GO:0072318 | clathrin coat disassembly | 8.1081 | 8 | yes |
| GO:0072319 | vesicle uncoating | 8.1081 | 7 | yes |
| GO:0016191 | synaptic vesicle uncoating | 6.7568 | 9 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| KCMA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CBP_HUMAN | [view interactions] | Low throughput | no | yes |
| ANM1_HUMAN | [view interactions] | Low throughput | no | yes |
| KHDR1_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FBX32_HUMAN | [view interactions] | Low throughput | no | no |
| SRBS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ITCH_HUMAN | [view interactions] | Low throughput | no | yes |
| ADA10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SYNJ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAPH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PDC6I_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SH3G1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SH3G3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VGLU1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DPPA4_HUMAN | [view interactions] | Low throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRGP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
| RHG08_HUMAN | [view interactions] | Low throughput | no | yes |
| CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RS30_HUMAN | [view interactions] | Low throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AXIN1_HUMAN | [view interactions] | High throughput | no | yes |
| STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITSN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EEIG1_HUMAN | [view interactions] | High throughput | no | no |
| NTM2F_HUMAN | [view interactions] | High throughput | no | no |
| CKLF5_HUMAN | [view interactions] | High throughput | no | yes |
| P4K2A_HUMAN | [view interactions] | High throughput | no | yes |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE2_HUMAN | [view interactions] | High throughput | no | no |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| TRIP4_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CGAS_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| M4K3_HUMAN | [view interactions] | High throughput | no | no |
| M4K5_HUMAN | [view interactions] | High throughput | no | no |
| RL35A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANGL2_HUMAN | [view interactions] | High throughput | no | no |
| STX17_HUMAN | [view interactions] | High throughput | no | yes |
| S10A2_HUMAN | [view interactions] | High throughput | no | no |
| MILK1_HUMAN | [view interactions] | High throughput | no | yes |
| MA7D2_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTNG1_HUMAN | [view interactions] | High throughput | no | no |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| MBNL1_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| GLRX3_HUMAN | [view interactions] | High throughput | no | yes |
| EMAL4_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E2F4_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMDH1_HUMAN | [view interactions] | High throughput | no | yes |
| AASD1_HUMAN | [view interactions] | High throughput | no | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AN32B_HUMAN | [view interactions] | High throughput | no | yes |
| ARC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARPC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP5L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| CALR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| CRTAP_HUMAN | [view interactions] | High throughput | no | yes |
| T2EA_HUMAN | [view interactions] | High throughput | no | yes |
| T2FB_HUMAN | [view interactions] | High throughput | no | yes |
| KBP_HUMAN | [view interactions] | High throughput | no | yes |
| AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NIF3L_HUMAN | [view interactions] | High throughput | no | yes |
| NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
| PFD1_HUMAN | [view interactions] | High throughput | no | yes |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM10A_HUMAN | [view interactions] | High throughput | no | no |
| SHLB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| THG1_HUMAN | [view interactions] | High throughput | no | yes |
| PRPK_HUMAN | [view interactions] | High throughput | no | yes |
| TPRKB_HUMAN | [view interactions] | High throughput | no | yes |
| TTC1_HUMAN | [view interactions] | High throughput | no | yes |
| SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| GLU2B_HUMAN | [view interactions] | High throughput | no | yes |
| MCM7_HUMAN | [view interactions] | High throughput | no | no |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| GANAB_HUMAN | [view interactions] | High throughput | no | yes |
| RPA2_HUMAN | [view interactions] | High throughput | no | no |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| DCA15_HUMAN | [view interactions] | High throughput | no | no |
| DC1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BICD1_HUMAN | [view interactions] | High throughput | no | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| CNTP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPAST_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| RFA4_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| BLNK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| SH3G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPKOW_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SEPT8_HUMAN | [view interactions] | High throughput | no | no |
| DPYL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBCC1_HUMAN | [view interactions] | High throughput | no | no |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPX7_HUMAN | [view interactions] | High throughput | no | no |
| SGF29_HUMAN | [view interactions] | High throughput | no | yes |
| CO8G_HUMAN | [view interactions] | High throughput | no | no |
| CAP7_HUMAN | [view interactions] | High throughput | no | no |
| ACM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DRD3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADA2B_HUMAN | [view interactions] | High throughput | no | no |
| ADRB3_HUMAN | [view interactions] | High throughput | no | no |
| HRH1_HUMAN | [view interactions] | High throughput | no | no |
| ADA2A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HRH3_HUMAN | [view interactions] | High throughput | no | no |
| DRD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NCF1_HUMAN | [view interactions] | High throughput | no | no |
| LRP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| SH24A_HUMAN | [view interactions] | High throughput | no | no |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAL2_HUMAN | [view interactions] | High throughput | no | no |
| VP37C_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS1_HUMAN | [view interactions] | High throughput | no | yes |
| SPG21_HUMAN | [view interactions] | High throughput | no | yes |
| MTA1_HUMAN | [view interactions] | High throughput | no | yes |
| PSB1_HUMAN | [view interactions] | High throughput | no | yes |
| PRB3_HUMAN | [view interactions] | High throughput | no | no |
| SCAM5_HUMAN | [view interactions] | High throughput | no | yes |
| CCD50_HUMAN | [view interactions] | High throughput | no | yes |
| RHEX_HUMAN | [view interactions] | High throughput | no | no |