SH3G1_HUMAN
Implicated in endocytosis. May recruit other proteins to membranes with high curvature . [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in SH3G1_HUMAN |
---|---|---|---|---|
GO:0019900 | kinase binding | 30.8824 | 4 | no |
GO:0019901 | protein kinase binding | 27.9412 | 5 | no |
GO:0017076 | purine nucleotide binding | 26.4706 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 26.4706 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 26.4706 | 4 | no |
GO:0046872 | metal ion binding | 22.0588 | 4 | no |
GO:0045296 | cadherin binding | 16.1765 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in SH3G1_HUMAN |
---|---|---|---|---|
GO:0051128 | regulation of cellular component organization | 61.7647 | 4 | no |
GO:0048522 | positive regulation of cellular process | 60.2941 | 4 | no |
GO:0048523 | negative regulation of cellular process | 52.9412 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | no |
GO:0010646 | regulation of cell communication | 48.5294 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 47.0588 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 45.5882 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 45.5882 | 4 | no |
GO:0009966 | regulation of signal transduction | 44.1176 | 4 | no |
GO:0051049 | regulation of transport | 42.6471 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 39.7059 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 36.7647 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 35.2941 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 35.2941 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 35.2941 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 35.2941 | 5 | no |
GO:0010468 | regulation of gene expression | 35.2941 | 5 | no |
GO:0022607 | cellular component assembly | 33.8235 | 4 | no |
GO:0006996 | organelle organization | 32.3529 | 4 | no |
GO:0051050 | positive regulation of transport | 32.3529 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 30.8824 | 4 | no |
GO:0033043 | regulation of organelle organization | 29.4118 | 5 | no |
GO:0016192 | vesicle-mediated transport | 29.4118 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 29.4118 | 5 | no |
GO:0010941 | regulation of cell death | 29.4118 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 29.4118 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 27.9412 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 27.9412 | 5 | no |
GO:0071310 | cellular response to organic substance | 27.9412 | 4 | no |
GO:0043933 | protein-containing complex organization | 26.4706 | 4 | yes |
GO:0001932 | regulation of protein phosphorylation | 26.4706 | 7 | no |
GO:0031399 | regulation of protein modification process | 26.4706 | 6 | no |
GO:0042325 | regulation of phosphorylation | 26.4706 | 7 | no |
GO:0051247 | positive regulation of protein metabolic process | 26.4706 | 6 | no |
GO:0060341 | regulation of cellular localization | 26.4706 | 4 | no |
GO:0009892 | negative regulation of metabolic process | 26.4706 | 4 | no |
GO:0042981 | regulation of apoptotic process | 26.4706 | 6 | no |
GO:0043067 | regulation of programmed cell death | 26.4706 | 5 | no |
GO:0008104 | protein localization | 25.0000 | 4 | no |
GO:0060627 | regulation of vesicle-mediated transport | 25.0000 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 25.0000 | 5 | no |
GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | no |
GO:0023056 | positive regulation of signaling | 25.0000 | 4 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 23.5294 | 4 | no |
GO:0031344 | regulation of cell projection organization | 23.5294 | 5 | no |
GO:0032880 | regulation of protein localization | 23.5294 | 5 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 23.5294 | 6 | no |
GO:0009889 | regulation of biosynthetic process | 23.5294 | 4 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.5294 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 23.5294 | 5 | no |
GO:0030030 | cell projection organization | 22.0588 | 4 | no |
GO:0097435 | supramolecular fiber organization | 22.0588 | 4 | no |
GO:0031401 | positive regulation of protein modification process | 22.0588 | 7 | no |
GO:0036211 | protein modification process | 22.0588 | 4 | no |
GO:0043412 | macromolecule modification | 22.0588 | 4 | no |
GO:0043269 | regulation of ion transport | 22.0588 | 5 | no |
GO:0010243 | response to organonitrogen compound | 22.0588 | 4 | no |
GO:0050804 | modulation of chemical synaptic transmission | 22.0588 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 22.0588 | 4 | no |
GO:1901701 | cellular response to oxygen-containing compound | 22.0588 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 22.0588 | 5 | no |
GO:0001934 | positive regulation of protein phosphorylation | 20.5882 | 8 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 20.5882 | 6 | no |
GO:0042327 | positive regulation of phosphorylation | 20.5882 | 8 | no |
GO:0045595 | regulation of cell differentiation | 20.5882 | 4 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 20.5882 | 7 | no |
GO:0031324 | negative regulation of cellular metabolic process | 20.5882 | 5 | no |
GO:0034762 | regulation of transmembrane transport | 20.5882 | 4 | no |
GO:0043085 | positive regulation of catalytic activity | 20.5882 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 20.5882 | 5 | no |
GO:0051336 | regulation of hydrolase activity | 20.5882 | 4 | no |
GO:0051338 | regulation of transferase activity | 20.5882 | 4 | no |
GO:0014070 | response to organic cyclic compound | 20.5882 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 20.5882 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 20.5882 | 5 | no |
GO:0060548 | negative regulation of cell death | 20.5882 | 5 | no |
GO:0022411 | cellular component disassembly | 11.7647 | 4 | yes |
GO:0032984 | protein-containing complex disassembly | 8.8235 | 5 | yes |
GO:0051261 | protein depolymerization | 8.8235 | 6 | yes |
GO:0007417 | central nervous system development | 7.3529 | 4 | yes |
GO:0016191 | synaptic vesicle uncoating | 7.3529 | 9 | yes |
GO:0072318 | clathrin coat disassembly | 7.3529 | 8 | yes |
GO:0072319 | vesicle uncoating | 7.3529 | 7 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in SH3G1_HUMAN |
---|---|---|---|---|
DOID:574 | peripheral nervous system disease | 2.9412 | 3 | no |
DOID:870 | neuropathy | 2.9412 | 4 | no |
DOID:0050700 | cardiomyopathy | 2.9412 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 2.9412 | 5 | no |
DOID:114 | heart disease | 2.9412 | 3 | no |
DOID:2843 | long QT syndrome | 2.9412 | 6 | no |
DOID:0050890 | synucleinopathy | 2.9412 | 5 | no |
DOID:0060894 | early-onset Parkinsons disease | 2.9412 | 7 | no |
DOID:1289 | neurodegenerative disease | 2.9412 | 4 | no |
DOID:14330 | Parkinsons disease | 2.9412 | 6 | no |
DOID:331 | central nervous system disease | 2.9412 | 3 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
ANM1_HUMAN | [view interactions] | Low throughput | no | yes |
KHDR1_HUMAN | [view interactions] | Low throughput | no | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FBX32_HUMAN | [view interactions] | Low throughput | no | no |
SRBS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ITCH_HUMAN | [view interactions] | Low throughput | no | yes |
ADA10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SYNJ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RAPH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SH3K1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PDC6I_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SH3G1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SH3G3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
VGLU1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
DPPA4_HUMAN | [view interactions] | Low throughput | no | no |
PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRGP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
RHG08_HUMAN | [view interactions] | Low throughput | no | yes |
CALM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RS30_HUMAN | [view interactions] | Low throughput | no | yes |
KCMA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CBP_HUMAN | [view interactions] | Low throughput | no | yes |
P4K2A_HUMAN | [view interactions] | High throughput | no | yes |
MERL_HUMAN | [view interactions] | High throughput | no | yes |
PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
TPTE2_HUMAN | [view interactions] | High throughput | no | no |
KC1A_HUMAN | [view interactions] | High throughput | no | yes |
TRIP4_HUMAN | [view interactions] | High throughput | no | yes |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CGAS_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
BRD4_HUMAN | [view interactions] | High throughput | no | yes |
MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RIN3_HUMAN | [view interactions] | High throughput | no | yes |
DDX58_HUMAN | [view interactions] | High throughput | no | yes |
TULP3_HUMAN | [view interactions] | High throughput | no | yes |
M4K3_HUMAN | [view interactions] | High throughput | no | no |
M4K5_HUMAN | [view interactions] | High throughput | no | no |
RL35A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ANGL2_HUMAN | [view interactions] | High throughput | no | no |
STX17_HUMAN | [view interactions] | High throughput | no | yes |
S10A2_HUMAN | [view interactions] | High throughput | no | no |
MILK1_HUMAN | [view interactions] | High throughput | no | yes |
MA7D2_HUMAN | [view interactions] | High throughput | no | yes |
DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NTNG1_HUMAN | [view interactions] | High throughput | no | no |
CCR1_HUMAN | [view interactions] | High throughput | no | no |
MBNL1_HUMAN | [view interactions] | High throughput | no | yes |
ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
GLRX3_HUMAN | [view interactions] | High throughput | no | yes |
EMAL4_HUMAN | [view interactions] | High throughput | no | yes |
HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IMDH1_HUMAN | [view interactions] | High throughput | no | yes |
AASD1_HUMAN | [view interactions] | High throughput | no | yes |
ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AN32B_HUMAN | [view interactions] | High throughput | no | yes |
ARC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ARPC5_HUMAN | [view interactions] | High throughput | no | yes |
ARP5L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAG1_HUMAN | [view interactions] | High throughput | no | yes |
CALR_HUMAN | [view interactions] | High throughput | no | yes |
CALU_HUMAN | [view interactions] | High throughput | no | yes |
CRTAP_HUMAN | [view interactions] | High throughput | no | yes |
T2EA_HUMAN | [view interactions] | High throughput | no | yes |
T2FB_HUMAN | [view interactions] | High throughput | no | yes |
KBP_HUMAN | [view interactions] | High throughput | no | yes |
AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NIF3L_HUMAN | [view interactions] | High throughput | no | yes |
NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
PFD1_HUMAN | [view interactions] | High throughput | no | yes |
PFD5_HUMAN | [view interactions] | High throughput | no | yes |
KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TM10A_HUMAN | [view interactions] | High throughput | no | no |
SHLB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
THG1_HUMAN | [view interactions] | High throughput | no | yes |
PRPK_HUMAN | [view interactions] | High throughput | no | yes |
TPRKB_HUMAN | [view interactions] | High throughput | no | yes |
TTC1_HUMAN | [view interactions] | High throughput | no | yes |
SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EWS_HUMAN | [view interactions] | High throughput | no | yes |
CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GBF1_HUMAN | [view interactions] | High throughput | no | yes |
DCA15_HUMAN | [view interactions] | High throughput | no | no |
DC1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BICD1_HUMAN | [view interactions] | High throughput | no | yes |
BICD2_HUMAN | [view interactions] | High throughput | no | yes |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
VASP_HUMAN | [view interactions] | High throughput | no | yes |
VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NAA40_HUMAN | [view interactions] | High throughput | no | no |
RNF43_HUMAN | [view interactions] | High throughput | no | yes |
DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DYN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
P85A_HUMAN | [view interactions] | High throughput | no | yes |
BLNK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
P85B_HUMAN | [view interactions] | High throughput | no | yes |
SH3G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GPKOW_HUMAN | [view interactions] | High throughput | no | yes |
PML_HUMAN | [view interactions] | High throughput | no | yes |
PTPRO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SEPT8_HUMAN | [view interactions] | High throughput | no | no |
DPYL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RBCC1_HUMAN | [view interactions] | High throughput | no | no |
OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GPX7_HUMAN | [view interactions] | High throughput | no | no |
SGF29_HUMAN | [view interactions] | High throughput | no | yes |
CO8G_HUMAN | [view interactions] | High throughput | no | no |
CAP7_HUMAN | [view interactions] | High throughput | no | no |
ACM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DRD3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ACM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADA2B_HUMAN | [view interactions] | High throughput | no | no |
ADRB3_HUMAN | [view interactions] | High throughput | no | no |
HRH1_HUMAN | [view interactions] | High throughput | no | no |
HRH3_HUMAN | [view interactions] | High throughput | no | no |
ADA2A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DRD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NCF1_HUMAN | [view interactions] | High throughput | no | no |
LRP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
SH24A_HUMAN | [view interactions] | High throughput | no | no |
B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAL2_HUMAN | [view interactions] | High throughput | no | no |
VP37C_HUMAN | [view interactions] | High throughput | no | yes |
SOCS1_HUMAN | [view interactions] | High throughput | no | yes |
SPG21_HUMAN | [view interactions] | High throughput | no | yes |
MTA1_HUMAN | [view interactions] | High throughput | no | yes |
PSB1_HUMAN | [view interactions] | High throughput | no | yes |
PRB3_HUMAN | [view interactions] | High throughput | no | no |
SCAM5_HUMAN | [view interactions] | High throughput | no | yes |
CCD50_HUMAN | [view interactions] | High throughput | no | yes |
RHEX_HUMAN | [view interactions] | High throughput | no | no |
HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AXIN1_HUMAN | [view interactions] | High throughput | no | yes |
STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITSN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
F102A_HUMAN | [view interactions] | High throughput | no | no |
NTM2F_HUMAN | [view interactions] | High throughput | no | no |
CKLF5_HUMAN | [view interactions] | High throughput | no | yes |
SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
YES_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CBL_HUMAN | [view interactions] | Computational | no | yes |
ARC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
FAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PTN3_HUMAN | [view interactions] | Computational | no | yes |
LCK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
FYN_HUMAN | [view entry] [view interactions] | Computational | yes | no |