Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SH3G1_HUMAN

Implicated in endocytosis. May recruit other proteins to membranes with high curvature . [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in SH3G1_HUMAN
GO:0019900 kinase binding 30.8824 4 no
GO:0019901 protein kinase binding 27.9412 5 no
GO:0017076 purine nucleotide binding 26.4706 4 no
GO:0032555 purine ribonucleotide binding 26.4706 4 no
GO:0035639 purine ribonucleoside triphosphate binding 26.4706 4 no
GO:0046872 metal ion binding 22.0588 4 no
GO:0045296 cadherin binding 16.1765 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in SH3G1_HUMAN
GO:0051128 regulation of cellular component organization 61.7647 4 no
GO:0048522 positive regulation of cellular process 60.2941 4 no
GO:0048523 negative regulation of cellular process 52.9412 4 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0010646 regulation of cell communication 48.5294 4 no
GO:0080090 regulation of primary metabolic process 47.0588 4 no
GO:0031323 regulation of cellular metabolic process 45.5882 4 no
GO:0051171 regulation of nitrogen compound metabolic process 45.5882 4 no
GO:0009966 regulation of signal transduction 44.1176 4 no
GO:0051049 regulation of transport 42.6471 4 no
GO:0009893 positive regulation of metabolic process 39.7059 4 no
GO:0010604 positive regulation of macromolecule metabolic process 36.7647 5 no
GO:0031325 positive regulation of cellular metabolic process 35.2941 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 35.2941 5 no
GO:0051246 regulation of protein metabolic process 35.2941 5 no
GO:1902531 regulation of intracellular signal transduction 35.2941 5 no
GO:0010468 regulation of gene expression 35.2941 5 no
GO:0022607 cellular component assembly 33.8235 4 no
GO:0006996 organelle organization 32.3529 4 no
GO:0051050 positive regulation of transport 32.3529 4 no
GO:0044087 regulation of cellular component biogenesis 30.8824 4 no
GO:0033043 regulation of organelle organization 29.4118 5 no
GO:0016192 vesicle-mediated transport 29.4118 4 no
GO:0051130 positive regulation of cellular component organization 29.4118 5 no
GO:0010941 regulation of cell death 29.4118 4 no
GO:0048584 positive regulation of response to stimulus 29.4118 4 no
GO:0019220 regulation of phosphate metabolic process 27.9412 6 no
GO:0051174 regulation of phosphorus metabolic process 27.9412 5 no
GO:0071310 cellular response to organic substance 27.9412 4 no
GO:0043933 protein-containing complex organization 26.4706 4 yes
GO:0001932 regulation of protein phosphorylation 26.4706 7 no
GO:0031399 regulation of protein modification process 26.4706 6 no
GO:0042325 regulation of phosphorylation 26.4706 7 no
GO:0051247 positive regulation of protein metabolic process 26.4706 6 no
GO:0060341 regulation of cellular localization 26.4706 4 no
GO:0009892 negative regulation of metabolic process 26.4706 4 no
GO:0042981 regulation of apoptotic process 26.4706 6 no
GO:0043067 regulation of programmed cell death 26.4706 5 no
GO:0008104 protein localization 25.0000 4 no
GO:0060627 regulation of vesicle-mediated transport 25.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 25.0000 5 no
GO:0010647 positive regulation of cell communication 25.0000 5 no
GO:0023056 positive regulation of signaling 25.0000 4 no
GO:0022603 regulation of anatomical structure morphogenesis 23.5294 4 no
GO:0031344 regulation of cell projection organization 23.5294 5 no
GO:0032880 regulation of protein localization 23.5294 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 23.5294 6 no
GO:0009889 regulation of biosynthetic process 23.5294 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 23.5294 5 no
GO:0031326 regulation of cellular biosynthetic process 23.5294 5 no
GO:0030030 cell projection organization 22.0588 4 no
GO:0097435 supramolecular fiber organization 22.0588 4 no
GO:0031401 positive regulation of protein modification process 22.0588 7 no
GO:0036211 protein modification process 22.0588 4 no
GO:0043412 macromolecule modification 22.0588 4 no
GO:0043269 regulation of ion transport 22.0588 5 no
GO:0010243 response to organonitrogen compound 22.0588 4 no
GO:0050804 modulation of chemical synaptic transmission 22.0588 5 no
GO:0099177 regulation of trans-synaptic signaling 22.0588 4 no
GO:1901701 cellular response to oxygen-containing compound 22.0588 4 no
GO:0010556 regulation of macromolecule biosynthetic process 22.0588 5 no
GO:0001934 positive regulation of protein phosphorylation 20.5882 8 no
GO:0010562 positive regulation of phosphorus metabolic process 20.5882 6 no
GO:0042327 positive regulation of phosphorylation 20.5882 8 no
GO:0045595 regulation of cell differentiation 20.5882 4 no
GO:0045937 positive regulation of phosphate metabolic process 20.5882 7 no
GO:0031324 negative regulation of cellular metabolic process 20.5882 5 no
GO:0034762 regulation of transmembrane transport 20.5882 4 no
GO:0043085 positive regulation of catalytic activity 20.5882 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 20.5882 5 no
GO:0051336 regulation of hydrolase activity 20.5882 4 no
GO:0051338 regulation of transferase activity 20.5882 4 no
GO:0014070 response to organic cyclic compound 20.5882 4 no
GO:0051252 regulation of RNA metabolic process 20.5882 5 no
GO:0009967 positive regulation of signal transduction 20.5882 5 no
GO:0060548 negative regulation of cell death 20.5882 5 no
GO:0022411 cellular component disassembly 11.7647 4 yes
GO:0032984 protein-containing complex disassembly 8.8235 5 yes
GO:0051261 protein depolymerization 8.8235 6 yes
GO:0007417 central nervous system development 7.3529 4 yes
GO:0016191 synaptic vesicle uncoating 7.3529 9 yes
GO:0072318 clathrin coat disassembly 7.3529 8 yes
GO:0072319 vesicle uncoating 7.3529 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in SH3G1_HUMAN
DOID:574 peripheral nervous system disease 2.9412 3 no
DOID:870 neuropathy 2.9412 4 no
DOID:0050700 cardiomyopathy 2.9412 4 no
DOID:0060036 intrinsic cardiomyopathy 2.9412 5 no
DOID:114 heart disease 2.9412 3 no
DOID:2843 long QT syndrome 2.9412 6 no
DOID:0050890 synucleinopathy 2.9412 5 no
DOID:0060894 early-onset Parkinsons disease 2.9412 7 no
DOID:1289 neurodegenerative disease 2.9412 4 no
DOID:14330 Parkinsons disease 2.9412 6 no
DOID:331 central nervous system disease 2.9412 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ANM1_HUMAN [view interactions] Low throughput no yes
KHDR1_HUMAN [view interactions] Low throughput no yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
FBX32_HUMAN [view interactions] Low throughput no no
SRBS2_HUMAN [view entry] [view interactions] Low throughput yes no
ITCH_HUMAN [view interactions] Low throughput no yes
ADA10_HUMAN [view entry] [view interactions] Low throughput yes yes
SYNJ1_HUMAN [view entry] [view interactions] Low throughput yes yes
DYN1_HUMAN [view entry] [view interactions] Low throughput yes yes
RAPH1_HUMAN [view entry] [view interactions] Low throughput yes yes
SH3K1_HUMAN [view entry] [view interactions] Low throughput yes yes
PDC6I_HUMAN [view entry] [view interactions] Low throughput yes yes
SH3G1_HUMAN [view entry] [view interactions] Low throughput yes no
SH3G3_HUMAN [view entry] [view interactions] Low throughput yes no
VGLU1_HUMAN [view entry] [view interactions] Low throughput yes no
DPPA4_HUMAN [view interactions] Low throughput no no
PRKN_HUMAN [view entry] [view interactions] Low throughput yes yes
SRGP3_HUMAN [view entry] [view interactions] Low throughput yes yes
LRRK2_HUMAN [view interactions] Low throughput no yes
RHG08_HUMAN [view interactions] Low throughput no yes
CALM2_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM3_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM1_HUMAN [view entry] [view interactions] Low throughput yes yes
RS30_HUMAN [view interactions] Low throughput no yes
KCMA1_HUMAN [view entry] [view interactions] Low throughput yes no
A4_HUMAN [view entry] [view interactions] Low throughput yes yes
CBP_HUMAN [view interactions] Low throughput no yes
P4K2A_HUMAN [view interactions] High throughput no yes
MERL_HUMAN [view interactions] High throughput no yes
PO5F1_HUMAN [view interactions] High throughput no yes
TPTE2_HUMAN [view interactions] High throughput no no
KC1A_HUMAN [view interactions] High throughput no yes
TRIP4_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
RASH_HUMAN [view entry] [view interactions] High throughput yes no
RECQ4_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
CGAS_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
RIN3_HUMAN [view interactions] High throughput no yes
DDX58_HUMAN [view interactions] High throughput no yes
TULP3_HUMAN [view interactions] High throughput no yes
M4K3_HUMAN [view interactions] High throughput no no
M4K5_HUMAN [view interactions] High throughput no no
RL35A_HUMAN [view entry] [view interactions] High throughput yes no
ANGL2_HUMAN [view interactions] High throughput no no
STX17_HUMAN [view interactions] High throughput no yes
S10A2_HUMAN [view interactions] High throughput no no
MILK1_HUMAN [view interactions] High throughput no yes
MA7D2_HUMAN [view interactions] High throughput no yes
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
NTNG1_HUMAN [view interactions] High throughput no no
CCR1_HUMAN [view interactions] High throughput no no
MBNL1_HUMAN [view interactions] High throughput no yes
ZBTB2_HUMAN [view interactions] High throughput no yes
GLRX3_HUMAN [view interactions] High throughput no yes
EMAL4_HUMAN [view interactions] High throughput no yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
IMDH1_HUMAN [view interactions] High throughput no yes
AASD1_HUMAN [view interactions] High throughput no yes
ARP3_HUMAN [view entry] [view interactions] High throughput yes yes
ARPC2_HUMAN [view entry] [view interactions] High throughput yes yes
FUBP1_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
ARP2_HUMAN [view entry] [view interactions] High throughput yes yes
AN32B_HUMAN [view interactions] High throughput no yes
ARC1A_HUMAN [view entry] [view interactions] High throughput yes yes
ARPC4_HUMAN [view entry] [view interactions] High throughput yes no
ARPC5_HUMAN [view interactions] High throughput no yes
ARP5L_HUMAN [view entry] [view interactions] High throughput yes yes
BAG1_HUMAN [view interactions] High throughput no yes
CALR_HUMAN [view interactions] High throughput no yes
CALU_HUMAN [view interactions] High throughput no yes
CRTAP_HUMAN [view interactions] High throughput no yes
T2EA_HUMAN [view interactions] High throughput no yes
T2FB_HUMAN [view interactions] High throughput no yes
KBP_HUMAN [view interactions] High throughput no yes
AMPL_HUMAN [view entry] [view interactions] High throughput yes no
NIF3L_HUMAN [view interactions] High throughput no yes
NSUN2_HUMAN [view interactions] High throughput no yes
PFD1_HUMAN [view interactions] High throughput no yes
PFD5_HUMAN [view interactions] High throughput no yes
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
TM10A_HUMAN [view interactions] High throughput no no
SHLB2_HUMAN [view entry] [view interactions] High throughput yes no
THG1_HUMAN [view interactions] High throughput no yes
PRPK_HUMAN [view interactions] High throughput no yes
TPRKB_HUMAN [view interactions] High throughput no yes
TTC1_HUMAN [view interactions] High throughput no yes
SHLB1_HUMAN [view interactions] High throughput no yes
PDLI5_HUMAN [view entry] [view interactions] High throughput yes no
EWS_HUMAN [view interactions] High throughput no yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
GBF1_HUMAN [view interactions] High throughput no yes
DCA15_HUMAN [view interactions] High throughput no no
DC1L2_HUMAN [view entry] [view interactions] High throughput yes yes
BICD1_HUMAN [view interactions] High throughput no yes
BICD2_HUMAN [view interactions] High throughput no yes
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
VASP_HUMAN [view interactions] High throughput no yes
VINC_HUMAN [view entry] [view interactions] High throughput yes no
NAA40_HUMAN [view interactions] High throughput no no
RNF43_HUMAN [view interactions] High throughput no yes
DYN2_HUMAN [view entry] [view interactions] High throughput yes yes
DYN3_HUMAN [view entry] [view interactions] High throughput yes no
P85A_HUMAN [view interactions] High throughput no yes
BLNK_HUMAN [view entry] [view interactions] High throughput yes no
P85B_HUMAN [view interactions] High throughput no yes
SH3G2_HUMAN [view entry] [view interactions] High throughput yes yes
GPKOW_HUMAN [view interactions] High throughput no yes
PML_HUMAN [view interactions] High throughput no yes
PTPRO_HUMAN [view entry] [view interactions] High throughput yes no
SEPT8_HUMAN [view interactions] High throughput no no
DPYL4_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
VIME_HUMAN [view entry] [view interactions] High throughput yes no
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
RBCC1_HUMAN [view interactions] High throughput no no
OTUB1_HUMAN [view interactions] High throughput no yes
AURKA_HUMAN [view entry] [view interactions] High throughput yes no
GPX7_HUMAN [view interactions] High throughput no no
SGF29_HUMAN [view interactions] High throughput no yes
CO8G_HUMAN [view interactions] High throughput no no
CAP7_HUMAN [view interactions] High throughput no no
ACM4_HUMAN [view entry] [view interactions] High throughput yes yes
DRD3_HUMAN [view entry] [view interactions] High throughput yes no
ACM2_HUMAN [view entry] [view interactions] High throughput yes yes
ADRB1_HUMAN [view entry] [view interactions] High throughput yes yes
ADA2B_HUMAN [view interactions] High throughput no no
ADRB3_HUMAN [view interactions] High throughput no no
HRH1_HUMAN [view interactions] High throughput no no
HRH3_HUMAN [view interactions] High throughput no no
ADA2A_HUMAN [view entry] [view interactions] High throughput yes no
DRD4_HUMAN [view entry] [view interactions] High throughput yes no
NCF1_HUMAN [view interactions] High throughput no no
LRP4_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA7_HUMAN [view interactions] High throughput no yes
SH24A_HUMAN [view interactions] High throughput no no
B3GA1_HUMAN [view interactions] High throughput no yes
RHG01_HUMAN [view entry] [view interactions] High throughput yes yes
MAL2_HUMAN [view interactions] High throughput no no
VP37C_HUMAN [view interactions] High throughput no yes
SOCS1_HUMAN [view interactions] High throughput no yes
SPG21_HUMAN [view interactions] High throughput no yes
MTA1_HUMAN [view interactions] High throughput no yes
PSB1_HUMAN [view interactions] High throughput no yes
PRB3_HUMAN [view interactions] High throughput no no
SCAM5_HUMAN [view interactions] High throughput no yes
CCD50_HUMAN [view interactions] High throughput no yes
RHEX_HUMAN [view interactions] High throughput no no
HD_HUMAN [view entry] [view interactions] High throughput yes yes
AXIN1_HUMAN [view interactions] High throughput no yes
STXB1_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR1_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
ITSN2_HUMAN [view entry] [view interactions] High throughput yes yes
F102A_HUMAN [view interactions] High throughput no no
NTM2F_HUMAN [view interactions] High throughput no no
CKLF5_HUMAN [view interactions] High throughput no yes
SRC_HUMAN [view entry] [view interactions] Computational yes no
YES_HUMAN [view entry] [view interactions] Computational yes yes
CBL_HUMAN [view interactions] Computational no yes
ARC_HUMAN [view entry] [view interactions] Computational yes no
FAK1_HUMAN [view entry] [view interactions] Computational yes yes
PTN3_HUMAN [view interactions] Computational no yes
LCK_HUMAN [view entry] [view interactions] Computational yes no
FYN_HUMAN [view entry] [view interactions] Computational yes no