LRP4_HUMAN
Evidence for PS localization
Functions
Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes. May play an essential role in the process of digit differentiation . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 137 | Asp | Asn | Cenani-Lenzsyndactylysyndrome(CLSS) | - |
| 160 | Cys | Tyr | Cenani-Lenzsyndactylysyndrome(CLSS) | - |
| 449 | Asp | Asn | Cenani-Lenzsyndactylysyndrome(CLSS) | - |
| 461 | Thr | Pro | Cenani-Lenzsyndactylysyndrome(CLSS) | - |
| 473 | Leu | Phe | Cenani-Lenzsyndactylysyndrome(CLSS) | - |
| 529 | Asp | Asn | Cenani-Lenzsyndactylysyndrome(CLSS) | - |
| 1017 | Cys | Arg | Cenani-Lenzsyndactylysyndrome(CLSS) | - |
| 1170 | Arg | Trp | Sclerosteosis2(SOST2) | - |
| 1186 | Trp | Ser | Sclerosteosis2(SOST2) | - |
| 1233 | Glu | Lys | Myasthenicsyndrome,congenital,17(CMS17) | - |
| 1277 | Arg | His | Myasthenicsyndrome,congenital,17(CMS17) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in LRP4_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 43.4783 | 4 | no |
| GO:0043168 | anion binding | 26.0870 | 4 | no |
| GO:0000166 | nucleotide binding | 23.9130 | 4 | no |
| GO:0017076 | purine nucleotide binding | 23.9130 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 21.7391 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 21.7391 | 4 | no |
| GO:0019900 | kinase binding | 17.3913 | 4 | yes |
| GO:0043169 | cation binding | 15.2174 | 4 | yes |
| GO:0046872 | metal ion binding | 15.2174 | 5 | yes |
| GO:0019901 | protein kinase binding | 13.0435 | 5 | yes |
| GO:0005509 | calcium ion binding | 8.6957 | 6 | yes |
| GO:0042803 | protein homodimerization activity | 6.5217 | 4 | yes |
| GO:0030971 | receptor tyrosine kinase binding | 4.3478 | 4 | yes |
| GO:1990782 | protein tyrosine kinase binding | 4.3478 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in LRP4_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 54.3478 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 54.3478 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 52.1739 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | yes |
| GO:0022607 | cellular component assembly | 43.4783 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 41.3043 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 41.3043 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 41.3043 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 39.1304 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.9565 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 36.9565 | 4 | no |
| GO:0010468 | regulation of gene expression | 36.9565 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 36.9565 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 36.9565 | 5 | no |
| GO:0009966 | regulation of signal transduction | 32.6087 | 4 | yes |
| GO:0010646 | regulation of cell communication | 32.6087 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 32.6087 | 4 | yes |
| GO:0006996 | organelle organization | 32.6087 | 4 | no |
| GO:0043933 | protein-containing complex organization | 32.6087 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 30.4348 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 30.4348 | 6 | yes |
| GO:0008104 | protein localization | 30.4348 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 28.2609 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 28.2609 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 28.2609 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 28.2609 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 28.2609 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 28.2609 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.2609 | 5 | no |
| GO:0031399 | regulation of protein modification process | 26.0870 | 6 | yes |
| GO:0051130 | positive regulation of cellular component organization | 26.0870 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.0870 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 26.0870 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 26.0870 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.9130 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 23.9130 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 23.9130 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 23.9130 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 23.9130 | 6 | no |
| GO:0009059 | macromolecule biosynthetic process | 23.9130 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 23.9130 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 21.7391 | 5 | yes |
| GO:0042325 | regulation of phosphorylation | 21.7391 | 7 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 21.7391 | 6 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 19.5652 | 4 | yes |
| GO:0030030 | cell projection organization | 19.5652 | 4 | yes |
| GO:0031401 | positive regulation of protein modification process | 19.5652 | 7 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 19.5652 | 6 | yes |
| GO:2000026 | regulation of multicellular organismal development | 19.5652 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 19.5652 | 7 | yes |
| GO:0009968 | negative regulation of signal transduction | 17.3913 | 5 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 17.3913 | 6 | yes |
| GO:0010648 | negative regulation of cell communication | 17.3913 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 17.3913 | 4 | yes |
| GO:0042327 | positive regulation of phosphorylation | 17.3913 | 8 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 17.3913 | 7 | yes |
| GO:0048585 | negative regulation of response to stimulus | 17.3913 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 17.3913 | 4 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 17.3913 | 8 | yes |
| GO:0050807 | regulation of synapse organization | 15.2174 | 5 | yes |
| GO:0051056 | regulation of small GTPase mediated signal transduction | 15.2174 | 6 | yes |
| GO:0072657 | protein localization to membrane | 15.2174 | 4 | yes |
| GO:0010975 | regulation of neuron projection development | 13.0435 | 7 | yes |
| GO:0032880 | regulation of protein localization | 13.0435 | 5 | yes |
| GO:0034330 | cell junction organization | 13.0435 | 4 | yes |
| GO:0043113 | receptor clustering | 13.0435 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 13.0435 | 5 | yes |
| GO:0051960 | regulation of nervous system development | 13.0435 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 13.0435 | 4 | yes |
| GO:0061024 | membrane organization | 13.0435 | 4 | yes |
| GO:0016055 | Wnt signaling pathway | 10.8696 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 10.8696 | 4 | yes |
| GO:0051057 | positive regulation of small GTPase mediated signal transduction | 10.8696 | 7 | yes |
| GO:0051093 | negative regulation of developmental process | 10.8696 | 4 | yes |
| GO:1905475 | regulation of protein localization to membrane | 10.8696 | 6 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 10.8696 | 4 | yes |
| GO:0034329 | cell junction assembly | 8.6957 | 5 | yes |
| GO:0035020 | regulation of Rac protein signal transduction | 8.6957 | 7 | yes |
| GO:0045596 | negative regulation of cell differentiation | 8.6957 | 5 | yes |
| GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 8.6957 | 8 | yes |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 8.6957 | 9 | yes |
| GO:0050767 | regulation of neurogenesis | 8.6957 | 6 | yes |
| GO:0050770 | regulation of axonogenesis | 8.6957 | 5 | yes |
| GO:0050808 | synapse organization | 8.6957 | 5 | yes |
| GO:0060284 | regulation of cell development | 8.6957 | 5 | yes |
| GO:0098657 | import into cell | 8.6957 | 4 | yes |
| GO:0007528 | neuromuscular junction development | 8.6957 | 6 | yes |
| GO:0010977 | negative regulation of neuron projection development | 6.5217 | 7 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 6.5217 | 5 | yes |
| GO:0031345 | negative regulation of cell projection organization | 6.5217 | 6 | yes |
| GO:0035022 | positive regulation of Rac protein signal transduction | 6.5217 | 8 | yes |
| GO:0048812 | neuron projection morphogenesis | 6.5217 | 5 | yes |
| GO:0071340 | skeletal muscle acetylcholine-gated channel clustering | 6.5217 | 6 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 6.5217 | 4 | yes |
| GO:1903829 | positive regulation of protein localization | 6.5217 | 5 | yes |
| GO:1905477 | positive regulation of protein localization to membrane | 6.5217 | 6 | yes |
| GO:0009953 | dorsal/ventral pattern formation | 4.3478 | 4 | yes |
| GO:0009954 | proximal/distal pattern formation | 4.3478 | 4 | yes |
| GO:0010721 | negative regulation of cell development | 4.3478 | 6 | yes |
| GO:0022008 | neurogenesis | 4.3478 | 4 | yes |
| GO:0030178 | negative regulation of Wnt signaling pathway | 4.3478 | 6 | yes |
| GO:0030278 | regulation of ossification | 4.3478 | 4 | yes |
| GO:0030279 | negative regulation of ossification | 4.3478 | 5 | yes |
| GO:0042475 | odontogenesis of dentin-containing tooth | 4.3478 | 5 | yes |
| GO:0042476 | odontogenesis | 4.3478 | 4 | yes |
| GO:0042733 | embryonic digit morphogenesis | 4.3478 | 4 | yes |
| GO:0048699 | generation of neurons | 4.3478 | 5 | yes |
| GO:0048813 | dendrite morphogenesis | 4.3478 | 6 | yes |
| GO:0050768 | negative regulation of neurogenesis | 4.3478 | 6 | yes |
| GO:0050771 | negative regulation of axonogenesis | 4.3478 | 6 | yes |
| GO:0051961 | negative regulation of nervous system development | 4.3478 | 5 | yes |
| GO:0060173 | limb development | 4.3478 | 4 | yes |
| GO:0060828 | regulation of canonical Wnt signaling pathway | 4.3478 | 6 | yes |
| GO:0071709 | membrane assembly | 4.3478 | 5 | yes |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway | 4.3478 | 7 | yes |
| GO:0097090 | presynaptic membrane organization | 4.3478 | 5 | yes |
| GO:0097104 | postsynaptic membrane assembly | 4.3478 | 6 | yes |
| GO:0097105 | presynaptic membrane assembly | 4.3478 | 6 | yes |
| GO:1901629 | regulation of presynaptic membrane organization | 4.3478 | 6 | yes |
| GO:1901631 | positive regulation of presynaptic membrane organization | 4.3478 | 6 | yes |
| GO:1903909 | regulation of receptor clustering | 4.3478 | 7 | yes |
| GO:1903911 | positive regulation of receptor clustering | 4.3478 | 7 | yes |
| GO:1904393 | regulation of skeletal muscle acetylcholine-gated channel clustering | 4.3478 | 8 | yes |
| GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering | 4.3478 | 8 | yes |
| GO:0001822 | kidney development | 4.3478 | 4 | yes |
| GO:0001941 | postsynaptic membrane organization | 4.3478 | 5 | yes |
| GO:0007416 | synapse assembly | 4.3478 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SOST_HUMAN | [view interactions] | Low throughput | no | no |
| AGRIN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PCLI1_HUMAN | [view interactions] | Low throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRP4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MUSK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| JIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RANB9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AMRP_HUMAN | [view interactions] | Low throughput | no | yes |
| CCAR2_HUMAN | [view interactions] | Low throughput | no | yes |
| MESD_HUMAN | [view interactions] | Low throughput | no | yes |
| PDIA4_HUMAN | [view interactions] | Low throughput | no | yes |
| RPN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SDF2L_HUMAN | [view interactions] | Low throughput | no | yes |
| EXOS5_HUMAN | [view interactions] | High throughput | no | yes |
| ZN398_HUMAN | [view interactions] | High throughput | no | no |
| ZFP41_HUMAN | [view interactions] | High throughput | no | no |
| ZN408_HUMAN | [view interactions] | High throughput | no | no |
| TYW3_HUMAN | [view interactions] | High throughput | no | yes |
| FCGRN_HUMAN | [view interactions] | High throughput | no | yes |
| ZN331_HUMAN | [view interactions] | High throughput | no | no |
| Z354C_HUMAN | [view interactions] | High throughput | no | no |
| GDF10_HUMAN | [view interactions] | High throughput | no | yes |
| ZN816_HUMAN | [view interactions] | High throughput | no | yes |
| ZSC26_HUMAN | [view interactions] | High throughput | no | no |
| ZN621_HUMAN | [view interactions] | High throughput | no | no |
| BEND7_HUMAN | [view interactions] | High throughput | no | no |
| ZN563_HUMAN | [view interactions] | High throughput | no | no |
| ZN669_HUMAN | [view interactions] | High throughput | no | no |
| ZN556_HUMAN | [view interactions] | High throughput | no | no |
| ZN224_HUMAN | [view interactions] | High throughput | no | yes |
| ZN214_HUMAN | [view interactions] | High throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MX1_HUMAN | [view interactions] | High throughput | no | yes |
| MOB1A_HUMAN | [view interactions] | High throughput | no | yes |
| SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
| ABCF1_HUMAN | [view interactions] | High throughput | no | yes |
| NHRF1_HUMAN | [view interactions] | High throughput | no | no |
| SERB1_HUMAN | [view interactions] | High throughput | no | yes |
| CDV3_HUMAN | [view interactions] | High throughput | no | no |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAHX_HUMAN | [view interactions] | High throughput | no | yes |
| LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 3HAO_HUMAN | [view interactions] | High throughput | no | no |
| EIF3E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIF2A_HUMAN | [view interactions] | High throughput | no | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX17_HUMAN | [view interactions] | High throughput | no | yes |
| EI2BE_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH3_HUMAN | [view interactions] | High throughput | no | no |
| EIF3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THUM1_HUMAN | [view interactions] | High throughput | no | yes |
| HMCS1_HUMAN | [view interactions] | High throughput | no | yes |
| CSRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PABP2_HUMAN | [view interactions] | High throughput | no | yes |
| NMT1_HUMAN | [view interactions] | High throughput | no | yes |
| IF5_HUMAN | [view interactions] | High throughput | no | yes |
| RL15_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPR1B_HUMAN | [view interactions] | High throughput | no | yes |
| ACBP_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC3_HUMAN | [view interactions] | High throughput | no | yes |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G6PD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERP29_HUMAN | [view interactions] | High throughput | no | yes |
| LMCD1_HUMAN | [view interactions] | High throughput | no | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD4_HUMAN | [view interactions] | High throughput | no | yes |
| NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3G1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PUM1_HUMAN | [view interactions] | High throughput | no | yes |
| RL8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ST1B1_HUMAN | [view interactions] | High throughput | no | no |
| ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHD4_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IF4H_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| DCXR_HUMAN | [view interactions] | High throughput | no | no |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| LCOR_HUMAN | [view interactions] | High throughput | no | yes |
| DSCR9_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| ZBBX_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| SLX4I_HUMAN | [view interactions] | High throughput | no | yes |
| BRD1_HUMAN | [view interactions] | High throughput | no | yes |
| SP110_HUMAN | [view interactions] | High throughput | no | no |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| AN36B_HUMAN | [view interactions] | High throughput | no | no |
| SHPK_HUMAN | [view interactions] | High throughput | no | no |
| ZN383_HUMAN | [view interactions] | High throughput | no | yes |
| ZN248_HUMAN | [view interactions] | High throughput | no | yes |
| FNDC8_HUMAN | [view interactions] | High throughput | no | no |
| ZNF34_HUMAN | [view interactions] | High throughput | no | no |
| ZSC21_HUMAN | [view interactions] | High throughput | no | yes |
| F120A_HUMAN | [view interactions] | High throughput | no | yes |
| NET5_HUMAN | [view interactions] | High throughput | no | no |
| ZN584_HUMAN | [view interactions] | High throughput | no | no |
| CX066_HUMAN | [view interactions] | High throughput | no | no |
| SULF2_HUMAN | [view interactions] | High throughput | no | yes |
| IGSF5_HUMAN | [view interactions] | High throughput | no | no |
| ZN778_HUMAN | [view interactions] | High throughput | no | yes |
| ZN121_HUMAN | [view interactions] | High throughput | no | no |
| ACSM3_HUMAN | [view interactions] | High throughput | no | yes |
| FST_HUMAN | [view interactions] | High throughput | no | no |
| DB123_HUMAN | [view interactions] | High throughput | no | no |
| IGFL3_HUMAN | [view interactions] | High throughput | no | no |
| MAP10_HUMAN | [view interactions] | High throughput | no | no |
| FEZF1_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF74_HUMAN | [view interactions] | High throughput | no | yes |
| EMX2_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF17_HUMAN | [view interactions] | High throughput | no | no |
| RL10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN707_HUMAN | [view interactions] | High throughput | no | yes |
| WDR20_HUMAN | [view interactions] | High throughput | no | no |
| ATS1_HUMAN | [view interactions] | High throughput | no | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM13_HUMAN | [view interactions] | High throughput | no | yes |
| THTR_HUMAN | [view interactions] | High throughput | no | yes |
| BPHL_HUMAN | [view interactions] | High throughput | no | no |
| LRP6_HUMAN | [view interactions] | High throughput | no | yes |
| LRP5_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WHRN_HUMAN | [view interactions] | High throughput | no | no |
| ARRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |