ARPC2_HUMAN
Evidence for PS localization
Functions
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed). Seems to contact the mother actin filament (PubMed). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ARPC2_HUMAN |
|---|---|---|---|---|
| GO:0003779 | actin binding | 44.5783 | 4 | yes |
| GO:0019900 | kinase binding | 32.5301 | 4 | no |
| GO:0019901 | protein kinase binding | 31.3253 | 5 | no |
| GO:0043169 | cation binding | 27.7108 | 4 | no |
| GO:0046872 | metal ion binding | 27.7108 | 5 | no |
| GO:0045296 | cadherin binding | 26.5060 | 4 | no |
| GO:0000166 | nucleotide binding | 26.5060 | 4 | no |
| GO:0017076 | purine nucleotide binding | 26.5060 | 5 | no |
| GO:0043168 | anion binding | 26.5060 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 25.3012 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 24.0964 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 21.6867 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.4819 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ARPC2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 61.4458 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 55.4217 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 55.4217 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 54.2169 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 54.2169 | 4 | no |
| GO:0006996 | organelle organization | 49.3976 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 46.9880 | 4 | no |
| GO:0022607 | cellular component assembly | 42.1687 | 4 | yes |
| GO:0010646 | regulation of cell communication | 40.9639 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 40.9639 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 39.7590 | 4 | no |
| GO:0010468 | regulation of gene expression | 38.5542 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 38.5542 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 38.5542 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 37.3494 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 36.1446 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 36.1446 | 5 | no |
| GO:0009966 | regulation of signal transduction | 34.9398 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 34.9398 | 5 | no |
| GO:0008104 | protein localization | 33.7349 | 4 | no |
| GO:0033043 | regulation of organelle organization | 32.5301 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 32.5301 | 5 | no |
| GO:0097435 | supramolecular fiber organization | 31.3253 | 4 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 28.9157 | 6 | yes |
| GO:0030030 | cell projection organization | 28.9157 | 4 | no |
| GO:0007015 | actin filament organization | 27.7108 | 5 | yes |
| GO:0051049 | regulation of transport | 27.7108 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 26.5060 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 26.5060 | 4 | no |
| GO:0032970 | regulation of actin filament-based process | 25.3012 | 4 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 25.3012 | 5 | yes |
| GO:0036211 | protein modification process | 25.3012 | 4 | no |
| GO:0043412 | macromolecule modification | 25.3012 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 25.3012 | 4 | no |
| GO:0032880 | regulation of protein localization | 25.3012 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 25.3012 | 5 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 24.0964 | 5 | yes |
| GO:0043933 | protein-containing complex organization | 24.0964 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 24.0964 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 24.0964 | 5 | no |
| GO:0110053 | regulation of actin filament organization | 22.8916 | 6 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 22.8916 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.8916 | 6 | no |
| GO:0031399 | regulation of protein modification process | 22.8916 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.8916 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.8916 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.8916 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 22.8916 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.8916 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.8916 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.6867 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 21.6867 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.6867 | 4 | no |
| GO:0071310 | cellular response to organic substance | 21.6867 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 20.4819 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.4819 | 6 | yes |
| GO:0051129 | negative regulation of cellular component organization | 20.4819 | 5 | no |
| GO:0043254 | regulation of protein-containing complex assembly | 16.8675 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 15.6627 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 15.6627 | 5 | yes |
| GO:0030155 | regulation of cell adhesion | 14.4578 | 4 | yes |
| GO:0010638 | positive regulation of organelle organization | 13.2530 | 6 | yes |
| GO:0032271 | regulation of protein polymerization | 13.2530 | 6 | yes |
| GO:0032535 | regulation of cellular component size | 13.2530 | 4 | yes |
| GO:0008064 | regulation of actin polymerization or depolymerization | 12.0482 | 6 | yes |
| GO:0030832 | regulation of actin filament length | 12.0482 | 5 | yes |
| GO:0030833 | regulation of actin filament polymerization | 10.8434 | 7 | yes |
| GO:0031346 | positive regulation of cell projection organization | 10.8434 | 6 | yes |
| GO:0051495 | positive regulation of cytoskeleton organization | 10.8434 | 7 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 10.8434 | 6 | yes |
| GO:0034314 | Arp2/3 complex-mediated actin nucleation | 9.6386 | 7 | yes |
| GO:0045010 | actin nucleation | 9.6386 | 6 | yes |
| GO:0060491 | regulation of cell projection assembly | 9.6386 | 5 | yes |
| GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 9.6386 | 6 | yes |
| GO:0031334 | positive regulation of protein-containing complex assembly | 8.4337 | 6 | yes |
| GO:0051258 | protein polymerization | 8.4337 | 6 | yes |
| GO:1902743 | regulation of lamellipodium organization | 8.4337 | 7 | yes |
| GO:0008154 | actin polymerization or depolymerization | 7.2289 | 6 | yes |
| GO:0010810 | regulation of cell-substrate adhesion | 7.2289 | 5 | yes |
| GO:1902745 | positive regulation of lamellipodium organization | 7.2289 | 7 | yes |
| GO:0010591 | regulation of lamellipodium assembly | 6.0241 | 7 | yes |
| GO:0032273 | positive regulation of protein polymerization | 6.0241 | 7 | yes |
| GO:0045785 | positive regulation of cell adhesion | 6.0241 | 5 | yes |
| GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 6.0241 | 6 | yes |
| GO:0010592 | positive regulation of lamellipodium assembly | 4.8193 | 7 | yes |
| GO:0030041 | actin filament polymerization | 4.8193 | 7 | yes |
| GO:1900024 | regulation of substrate adhesion-dependent cell spreading | 4.8193 | 6 | yes |
| GO:0030838 | positive regulation of actin filament polymerization | 3.6145 | 7 | yes |
| GO:0010811 | positive regulation of cell-substrate adhesion | 2.4096 | 6 | yes |
| GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 2.4096 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ACTS_HUMAN | [view interactions] | Low throughput | no | no |
| WASF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SSH1_HUMAN | [view interactions] | Low throughput | no | yes |
| WASP_HUMAN | [view interactions] | Low throughput | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARC1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARC1B_HUMAN | [view interactions] | Low throughput | no | no |
| ARPC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARPIN_HUMAN | [view interactions] | Low throughput | no | yes |
| ARPC5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARP5L_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COR1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SRC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PICK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PARD3_HUMAN | [view interactions] | Low throughput | no | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| UB2Q2_HUMAN | [view interactions] | Low throughput | no | no |
| AURKA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
| THG1_HUMAN | [view interactions] | High throughput | no | yes |
| TPD54_HUMAN | [view interactions] | High throughput | no | yes |
| TPRKB_HUMAN | [view interactions] | High throughput | no | yes |
| RHG17_HUMAN | [view interactions] | High throughput | no | no |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFHD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARLY_HUMAN | [view interactions] | High throughput | no | no |
| ACOX1_HUMAN | [view interactions] | High throughput | no | yes |
| OCTC_HUMAN | [view interactions] | High throughput | no | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| DOK2_HUMAN | [view interactions] | High throughput | no | no |
| NF2L2_HUMAN | [view interactions] | High throughput | no | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCRB2_HUMAN | [view interactions] | High throughput | no | yes |
| VMP1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| HTRA4_HUMAN | [view interactions] | High throughput | no | no |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| ARP3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CXCR2_HUMAN | [view interactions] | High throughput | no | no |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BCL7C_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RYK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
| CEP97_HUMAN | [view interactions] | High throughput | no | yes |
| CP110_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| GLI1_HUMAN | [view interactions] | High throughput | no | no |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN138_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RNF6_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPARG_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| ANO7_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| CHUR_HUMAN | [view interactions] | High throughput | no | yes |
| SMRD3_HUMAN | [view interactions] | High throughput | no | no |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTX3_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| SIK2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| PLK4_HUMAN | [view interactions] | High throughput | no | yes |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL14E_HUMAN | [view interactions] | High throughput | no | yes |
| ARL3_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| AR6P6_HUMAN | [view interactions] | High throughput | no | yes |
| ARL8B_HUMAN | [view interactions] | High throughput | no | yes |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| BOP1_HUMAN | [view interactions] | High throughput | no | yes |
| FA50A_HUMAN | [view interactions] | High throughput | no | yes |
| RM42_HUMAN | [view interactions] | High throughput | no | yes |
| DC1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIFC1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN830_HUMAN | [view interactions] | High throughput | no | yes |
| SIK3_HUMAN | [view interactions] | High throughput | no | yes |
| CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
| CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DBNL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK26_HUMAN | [view interactions] | High throughput | no | no |
| TPC2A_HUMAN | [view interactions] | High throughput | no | yes |
| UBP22_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| GATA4_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| ASXL1_HUMAN | [view interactions] | High throughput | no | no |
| ASXL2_HUMAN | [view interactions] | High throughput | no | no |
| ASXL3_HUMAN | [view interactions] | High throughput | no | no |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| MYO10_HUMAN | [view interactions] | High throughput | no | no |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM165_HUMAN | [view interactions] | High throughput | no | yes |
| ATG7_HUMAN | [view interactions] | High throughput | no | yes |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| AASD1_HUMAN | [view interactions] | High throughput | no | yes |
| AN32B_HUMAN | [view interactions] | High throughput | no | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRMB_HUMAN | [view interactions] | High throughput | no | yes |
| NIF3L_HUMAN | [view interactions] | High throughput | no | yes |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2A5D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUS1_HUMAN | [view interactions] | High throughput | no | yes |
| SH3G1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SUMO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNPO3_HUMAN | [view interactions] | High throughput | no | yes |
| TM1L1_HUMAN | [view interactions] | High throughput | no | yes |
| FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
| METH_HUMAN | [view interactions] | High throughput | no | yes |