ARPC2_HUMAN
Evidence for PS localization
Functions
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed). Seems to contact the mother actin filament (PubMed). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ARPC2_HUMAN |
|---|---|---|---|---|
| GO:0003779 | actin binding | 46.8354 | 4 | yes |
| GO:0045296 | cadherin binding | 30.3797 | 4 | no |
| GO:0019900 | kinase binding | 26.5823 | 4 | no |
| GO:0019901 | protein kinase binding | 25.3165 | 5 | no |
| GO:0046872 | metal ion binding | 25.3165 | 4 | no |
| GO:0017076 | purine nucleotide binding | 24.0506 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.7848 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.7848 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 20.2532 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ARPC2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 63.2911 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 60.7595 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 53.1646 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 51.8987 | 4 | no |
| GO:0006996 | organelle organization | 49.3671 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 48.1013 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.1013 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 46.8354 | 4 | no |
| GO:0022607 | cellular component assembly | 43.0380 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 40.5063 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 40.5063 | 4 | yes |
| GO:0010646 | regulation of cell communication | 39.2405 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 37.9747 | 6 | yes |
| GO:0009893 | positive regulation of metabolic process | 36.7089 | 4 | no |
| GO:0032970 | regulation of actin filament-based process | 35.4430 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 35.4430 | 5 | no |
| GO:0007010 | cytoskeleton organization | 35.4430 | 5 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 34.1772 | 5 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 34.1772 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 34.1772 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.1772 | 5 | no |
| GO:0010468 | regulation of gene expression | 34.1772 | 5 | no |
| GO:0110053 | regulation of actin filament organization | 32.9114 | 6 | yes |
| GO:0030030 | cell projection organization | 32.9114 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 31.6456 | 5 | yes |
| GO:0008104 | protein localization | 31.6456 | 4 | no |
| GO:0097435 | supramolecular fiber organization | 30.3797 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 30.3797 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 30.3797 | 5 | no |
| GO:0007015 | actin filament organization | 29.1139 | 5 | yes |
| GO:0051049 | regulation of transport | 29.1139 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 29.1139 | 5 | no |
| GO:0036211 | protein modification process | 25.3165 | 4 | no |
| GO:0043412 | macromolecule modification | 25.3165 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 25.3165 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 25.3165 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 22.7848 | 5 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 22.7848 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.7848 | 6 | yes |
| GO:0009892 | negative regulation of metabolic process | 22.7848 | 4 | no |
| GO:0031399 | regulation of protein modification process | 22.7848 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 22.7848 | 5 | no |
| GO:0060341 | regulation of cellular localization | 22.7848 | 4 | no |
| GO:0071310 | cellular response to organic substance | 22.7848 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.5190 | 4 | yes |
| GO:0032535 | regulation of cellular component size | 21.5190 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 21.5190 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 21.5190 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 21.5190 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 21.5190 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.5190 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 21.5190 | 5 | no |
| GO:0032880 | regulation of protein localization | 21.5190 | 5 | no |
| GO:0008064 | regulation of actin polymerization or depolymerization | 20.2532 | 6 | yes |
| GO:0030832 | regulation of actin filament length | 20.2532 | 5 | yes |
| GO:0032271 | regulation of protein polymerization | 20.2532 | 6 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 20.2532 | 5 | no |
| GO:0051050 | positive regulation of transport | 20.2532 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 20.2532 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 20.2532 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 20.2532 | 4 | no |
| GO:0030833 | regulation of actin filament polymerization | 18.9873 | 7 | yes |
| GO:0043933 | protein-containing complex organization | 18.9873 | 4 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 18.9873 | 5 | yes |
| GO:0010638 | positive regulation of organelle organization | 17.7215 | 6 | yes |
| GO:0022604 | regulation of cell morphogenesis | 16.4557 | 5 | yes |
| GO:0031346 | positive regulation of cell projection organization | 16.4557 | 6 | yes |
| GO:0051094 | positive regulation of developmental process | 16.4557 | 4 | yes |
| GO:0051495 | positive regulation of cytoskeleton organization | 16.4557 | 7 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 16.4557 | 6 | yes |
| GO:0060284 | regulation of cell development | 15.1899 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 15.1899 | 5 | yes |
| GO:0030155 | regulation of cell adhesion | 13.9241 | 4 | yes |
| GO:0045597 | positive regulation of cell differentiation | 13.9241 | 5 | yes |
| GO:0060491 | regulation of cell projection assembly | 12.6582 | 5 | yes |
| GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 12.6582 | 6 | yes |
| GO:1902743 | regulation of lamellipodium organization | 12.6582 | 7 | yes |
| GO:0010720 | positive regulation of cell development | 11.3924 | 6 | yes |
| GO:1902745 | positive regulation of lamellipodium organization | 11.3924 | 7 | yes |
| GO:0008154 | actin polymerization or depolymerization | 10.1266 | 6 | yes |
| GO:0010591 | regulation of lamellipodium assembly | 10.1266 | 7 | yes |
| GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 10.1266 | 6 | yes |
| GO:0010592 | positive regulation of lamellipodium assembly | 8.8608 | 7 | yes |
| GO:0010769 | regulation of cell morphogenesis involved in differentiation | 8.8608 | 6 | yes |
| GO:0031334 | positive regulation of protein-containing complex assembly | 8.8608 | 6 | yes |
| GO:0034314 | Arp2/3 complex-mediated actin nucleation | 8.8608 | 7 | yes |
| GO:0045010 | actin nucleation | 8.8608 | 6 | yes |
| GO:0010810 | regulation of cell-substrate adhesion | 7.5949 | 5 | yes |
| GO:0032273 | positive regulation of protein polymerization | 7.5949 | 7 | yes |
| GO:0051258 | protein polymerization | 7.5949 | 6 | yes |
| GO:0010770 | positive regulation of cell morphogenesis involved in differentiation | 6.3291 | 7 | yes |
| GO:0030041 | actin filament polymerization | 6.3291 | 7 | yes |
| GO:0030838 | positive regulation of actin filament polymerization | 6.3291 | 7 | yes |
| GO:0045785 | positive regulation of cell adhesion | 5.0633 | 5 | yes |
| GO:1900024 | regulation of substrate adhesion-dependent cell spreading | 5.0633 | 6 | yes |
| GO:0010811 | positive regulation of cell-substrate adhesion | 2.5316 | 6 | yes |
| GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 2.5316 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in ARPC2_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 5.0633 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 5.0633 | 5 | no |
| DOID:114 | heart disease | 5.0633 | 3 | no |
| DOID:2843 | long QT syndrome | 2.5316 | 6 | no |
| DOID:12930 | dilated cardiomyopathy | 2.5316 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ACTS_HUMAN | [view interactions] | Low throughput | no | no |
| WASF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SSH1_HUMAN | [view interactions] | Low throughput | no | yes |
| WASP_HUMAN | [view interactions] | Low throughput | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARC1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARPC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARC1B_HUMAN | [view interactions] | Low throughput | no | no |
| ARPIN_HUMAN | [view interactions] | Low throughput | no | yes |
| ARPC5_HUMAN | [view interactions] | Low throughput | no | yes |
| ARP5L_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COR1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SRC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PICK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PARD3_HUMAN | [view interactions] | Low throughput | no | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| UB2Q2_HUMAN | [view interactions] | Low throughput | no | no |
| AURKA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| DOK2_HUMAN | [view interactions] | High throughput | no | no |
| NF2L2_HUMAN | [view interactions] | High throughput | no | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCRB2_HUMAN | [view interactions] | High throughput | no | yes |
| VMP1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| HTRA4_HUMAN | [view interactions] | High throughput | no | no |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| ARP3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CXCR2_HUMAN | [view interactions] | High throughput | no | no |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BCL7C_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RYK_HUMAN | [view interactions] | High throughput | no | no |
| FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
| CEP97_HUMAN | [view interactions] | High throughput | no | yes |
| CP110_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| GLI1_HUMAN | [view interactions] | High throughput | no | no |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN138_HUMAN | [view interactions] | High throughput | no | no |
| RNF6_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPARG_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| ANO7_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| CHUR_HUMAN | [view interactions] | High throughput | no | yes |
| SMRD3_HUMAN | [view interactions] | High throughput | no | no |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTX3_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| SIK2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| PLK4_HUMAN | [view interactions] | High throughput | no | yes |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL14E_HUMAN | [view interactions] | High throughput | no | yes |
| ARL3_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| AR6P6_HUMAN | [view interactions] | High throughput | no | yes |
| ARL8B_HUMAN | [view interactions] | High throughput | no | yes |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| BOP1_HUMAN | [view interactions] | High throughput | no | yes |
| FA50A_HUMAN | [view interactions] | High throughput | no | yes |
| RM42_HUMAN | [view interactions] | High throughput | no | yes |
| DC1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIFC1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN830_HUMAN | [view interactions] | High throughput | no | yes |
| SIK3_HUMAN | [view interactions] | High throughput | no | yes |
| CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
| CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DBNL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK26_HUMAN | [view interactions] | High throughput | no | no |
| TPC2A_HUMAN | [view interactions] | High throughput | no | yes |
| UBP22_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM165_HUMAN | [view interactions] | High throughput | no | yes |
| ATG7_HUMAN | [view interactions] | High throughput | no | yes |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| AASD1_HUMAN | [view interactions] | High throughput | no | yes |
| AN32B_HUMAN | [view interactions] | High throughput | no | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRMB_HUMAN | [view interactions] | High throughput | no | yes |
| NIF3L_HUMAN | [view interactions] | High throughput | no | yes |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2A5D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRUA_HUMAN | [view interactions] | High throughput | no | yes |
| SH3G1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SUMO1_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO3_HUMAN | [view interactions] | High throughput | no | yes |
| TM1L1_HUMAN | [view interactions] | High throughput | no | yes |
| FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
| METH_HUMAN | [view interactions] | High throughput | no | yes |
| NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
| THG1_HUMAN | [view interactions] | High throughput | no | yes |
| TPD54_HUMAN | [view interactions] | High throughput | no | yes |
| TPRKB_HUMAN | [view interactions] | High throughput | no | yes |
| RHG17_HUMAN | [view interactions] | High throughput | no | no |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFHD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| PDGFB_HUMAN | [view interactions] | Computational | no | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FCG2A_HUMAN | [view interactions] | Computational | no | no |
| NCK1_HUMAN | [view interactions] | Computational | no | yes |
| GAB1_HUMAN | [view interactions] | Computational | no | yes |
| WASF2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CD3Z_HUMAN | [view interactions] | Computational | no | no |
| FCGR1_HUMAN | [view interactions] | Computational | no | no |
| BRK1_HUMAN | [view interactions] | Computational | no | no |
| PSA7_HUMAN | [view interactions] | Computational | no | yes |
| IGLL5_HUMAN | [view interactions] | Computational | no | no |
| PGFRB_HUMAN | [view interactions] | Computational | no | yes |
| SPN90_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ABI1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NCK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARP3C_HUMAN | [view interactions] | Computational | no | no |
| HCLS1_HUMAN | [view interactions] | Computational | no | no |
| CYFP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |