VGLU1_HUMAN
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in VGLU1_HUMAN |
---|---|---|---|---|
GO:0046872 | metal ion binding | 26.9231 | 4 | no |
GO:0008324 | cation transmembrane transporter activity | 11.5385 | 4 | yes |
GO:0008509 | anion transmembrane transporter activity | 11.5385 | 4 | yes |
GO:0022890 | inorganic cation transmembrane transporter activity | 11.5385 | 4 | yes |
GO:0046873 | metal ion transmembrane transporter activity | 11.5385 | 5 | yes |
GO:0005313 | L-glutamate transmembrane transporter activity | 7.6923 | 6 | yes |
GO:0008514 | organic anion transmembrane transporter activity | 7.6923 | 5 | yes |
GO:0015081 | sodium ion transmembrane transporter activity | 7.6923 | 6 | yes |
GO:0015171 | amino acid transmembrane transporter activity | 7.6923 | 5 | yes |
GO:0015172 | acidic amino acid transmembrane transporter activity | 7.6923 | 6 | yes |
GO:0015179 | L-amino acid transmembrane transporter activity | 7.6923 | 6 | yes |
GO:0015291 | secondary active transmembrane transporter activity | 7.6923 | 4 | yes |
GO:0015293 | symporter activity | 7.6923 | 5 | yes |
GO:0015294 | solute:cation symporter activity | 7.6923 | 5 | yes |
GO:0015370 | solute:sodium symporter activity | 7.6923 | 6 | yes |
GO:0022853 | active ion transmembrane transporter activity | 7.6923 | 4 | yes |
GO:0046943 | carboxylic acid transmembrane transporter activity | 7.6923 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in VGLU1_HUMAN |
---|---|---|---|---|
GO:0051049 | regulation of transport | 65.3846 | 4 | yes |
GO:0010646 | regulation of cell communication | 61.5385 | 4 | no |
GO:0048522 | positive regulation of cellular process | 57.6923 | 4 | no |
GO:0050804 | modulation of chemical synaptic transmission | 57.6923 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 57.6923 | 4 | no |
GO:0051128 | regulation of cellular component organization | 53.8462 | 4 | yes |
GO:0043933 | protein-containing complex organization | 50.0000 | 4 | no |
GO:0007268 | chemical synaptic transmission | 46.1538 | 6 | yes |
GO:0060627 | regulation of vesicle-mediated transport | 46.1538 | 4 | yes |
GO:0098916 | anterograde trans-synaptic signaling | 46.1538 | 5 | yes |
GO:0099537 | trans-synaptic signaling | 46.1538 | 4 | yes |
GO:0022607 | cellular component assembly | 46.1538 | 4 | no |
GO:0009966 | regulation of signal transduction | 38.4615 | 4 | no |
GO:0048523 | negative regulation of cellular process | 38.4615 | 4 | no |
GO:0016192 | vesicle-mediated transport | 38.4615 | 4 | no |
GO:0051046 | regulation of secretion | 38.4615 | 5 | no |
GO:1903530 | regulation of secretion by cell | 38.4615 | 4 | no |
GO:0071310 | cellular response to organic substance | 34.6154 | 4 | no |
GO:0010647 | positive regulation of cell communication | 34.6154 | 5 | no |
GO:0023056 | positive regulation of signaling | 34.6154 | 4 | no |
GO:0065003 | protein-containing complex assembly | 34.6154 | 5 | no |
GO:0099003 | vesicle-mediated transport in synapse | 34.6154 | 5 | no |
GO:0008104 | protein localization | 34.6154 | 4 | no |
GO:0006996 | organelle organization | 30.7692 | 4 | no |
GO:0023061 | signal release | 30.7692 | 4 | no |
GO:0046903 | secretion | 30.7692 | 4 | no |
GO:0050806 | positive regulation of synaptic transmission | 30.7692 | 5 | no |
GO:0099643 | signal release from synapse | 30.7692 | 5 | no |
GO:0031323 | regulation of cellular metabolic process | 30.7692 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 30.7692 | 4 | no |
GO:0043269 | regulation of ion transport | 30.7692 | 5 | no |
GO:0006836 | neurotransmitter transport | 26.9231 | 4 | yes |
GO:0006887 | exocytosis | 26.9231 | 4 | no |
GO:0006897 | endocytosis | 26.9231 | 5 | no |
GO:0016079 | synaptic vesicle exocytosis | 26.9231 | 4 | no |
GO:0032880 | regulation of protein localization | 26.9231 | 5 | no |
GO:0045055 | regulated exocytosis | 26.9231 | 5 | no |
GO:0060341 | regulation of cellular localization | 26.9231 | 4 | no |
GO:0061024 | membrane organization | 26.9231 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 26.9231 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 26.9231 | 6 | no |
GO:0031399 | regulation of protein modification process | 26.9231 | 6 | no |
GO:0033043 | regulation of organelle organization | 26.9231 | 5 | no |
GO:0034330 | cell junction organization | 26.9231 | 4 | no |
GO:0042325 | regulation of phosphorylation | 26.9231 | 7 | no |
GO:0050808 | synapse organization | 26.9231 | 5 | no |
GO:0051094 | positive regulation of developmental process | 26.9231 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 26.9231 | 5 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 26.9231 | 4 | no |
GO:0051174 | regulation of phosphorus metabolic process | 26.9231 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 26.9231 | 5 | no |
GO:0080090 | regulation of primary metabolic process | 26.9231 | 4 | no |
GO:0017157 | regulation of exocytosis | 26.9231 | 5 | no |
GO:0046928 | regulation of neurotransmitter secretion | 26.9231 | 4 | no |
GO:0051588 | regulation of neurotransmitter transport | 26.9231 | 5 | no |
GO:0034762 | regulation of transmembrane transport | 26.9231 | 4 | no |
GO:0051050 | positive regulation of transport | 26.9231 | 4 | no |
GO:0036211 | protein modification process | 23.0769 | 4 | no |
GO:0043412 | macromolecule modification | 23.0769 | 4 | no |
GO:0050890 | cognition | 23.0769 | 4 | no |
GO:0010038 | response to metal ion | 23.0769 | 4 | no |
GO:0010468 | regulation of gene expression | 23.0769 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 23.0769 | 5 | no |
GO:0030030 | cell projection organization | 23.0769 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 23.0769 | 5 | no |
GO:1901701 | cellular response to oxygen-containing compound | 23.0769 | 4 | no |
GO:1903829 | positive regulation of protein localization | 23.0769 | 5 | no |
GO:0071702 | organic substance transport | 23.0769 | 4 | no |
GO:0071705 | nitrogen compound transport | 23.0769 | 4 | no |
GO:0048168 | regulation of neuronal synaptic plasticity | 23.0769 | 4 | no |
GO:0034765 | regulation of ion transmembrane transport | 23.0769 | 5 | no |
GO:1904062 | regulation of cation transmembrane transport | 23.0769 | 6 | no |
GO:0001932 | regulation of protein phosphorylation | 23.0769 | 7 | no |
GO:0048584 | positive regulation of response to stimulus | 23.0769 | 4 | no |
GO:0030100 | regulation of endocytosis | 19.2308 | 5 | yes |
GO:0006811 | ion transport | 15.3846 | 4 | yes |
GO:0006820 | anion transport | 11.5385 | 5 | yes |
GO:0007420 | brain development | 11.5385 | 4 | yes |
GO:1903421 | regulation of synaptic vesicle recycling | 7.6923 | 5 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
SH3G3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SH3G2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SH3G1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DNJC5_HUMAN | [view interactions] | Low throughput | no | yes |
SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
APBB1_HUMAN | [view interactions] | High throughput | no | yes |
ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
PTPRT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TIA1_HUMAN | [view interactions] | High throughput | no | no |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VGLU2_HUMAN | [view interactions] | High throughput | no | no |
DCE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DCE2_HUMAN | [view interactions] | High throughput | no | yes |
PDE1B_HUMAN | [view interactions] | High throughput | no | yes |
VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CERS2_HUMAN | [view interactions] | High throughput | no | no |
EST1_HUMAN | [view interactions] | High throughput | no | no |
CNGA3_HUMAN | [view interactions] | High throughput | no | no |
CP2U1_HUMAN | [view interactions] | High throughput | no | yes |
CNGA1_HUMAN | [view interactions] | High throughput | no | no |
GUC2D_HUMAN | [view interactions] | High throughput | no | no |
S22A1_HUMAN | [view interactions] | High throughput | no | yes |
RIMS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SNP25_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
VMAT1_HUMAN | [view interactions] | Computational | no | no |
BSN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SYN1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
VIAAT_HUMAN | [view interactions] | Computational | no | yes |
SYT1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PRVA_HUMAN | [view interactions] | Computational | no | yes |
EAA2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GEPH_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAB3A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SYPH_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
VGLU3_HUMAN | [view interactions] | Computational | no | no |
CPLX1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
VAMP2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
VACHT_HUMAN | [view interactions] | Computational | no | no |