QOR_HUMAN
Evidence for PS localization
Functions
Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in QOR_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 40.3846 | 4 | yes |
| GO:0046872 | metal ion binding | 40.3846 | 5 | yes |
| GO:0043168 | anion binding | 34.6154 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 30.7692 | 5 | yes |
| GO:0000166 | nucleotide binding | 30.7692 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 26.9231 | 6 | yes |
| GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | 25.0000 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 21.1538 | 4 | no |
| GO:0008324 | monoatomic cation transmembrane transporter activity | 21.1538 | 4 | no |
| GO:0015078 | proton transmembrane transporter activity | 21.1538 | 5 | no |
| GO:0022853 | active monoatomic ion transmembrane transporter activity | 21.1538 | 4 | no |
| GO:0022890 | inorganic cation transmembrane transporter activity | 21.1538 | 4 | no |
| GO:0003723 | RNA binding | 21.1538 | 4 | yes |
| GO:0046914 | transition metal ion binding | 11.5385 | 6 | yes |
| GO:0003729 | mRNA binding | 9.6154 | 5 | yes |
| GO:0008270 | zinc ion binding | 7.6923 | 7 | yes |
| GO:0050661 | NADP binding | 5.7692 | 7 | yes |
| GO:0003730 | mRNA 3-UTR binding | 5.7692 | 6 | yes |
| GO:0070402 | NADPH binding | 3.8462 | 5 | yes |
| GO:0003960 | NADPH:quinone reductase activity | 3.8462 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in QOR_HUMAN |
|---|---|---|---|---|
| GO:0006796 | phosphate-containing compound metabolic process | 50.0000 | 4 | no |
| GO:0006753 | nucleoside phosphate metabolic process | 42.3077 | 4 | no |
| GO:0009117 | nucleotide metabolic process | 42.3077 | 5 | no |
| GO:0072521 | purine-containing compound metabolic process | 42.3077 | 4 | no |
| GO:0006163 | purine nucleotide metabolic process | 40.3846 | 5 | no |
| GO:0009150 | purine ribonucleotide metabolic process | 40.3846 | 6 | no |
| GO:0009259 | ribonucleotide metabolic process | 40.3846 | 5 | no |
| GO:0019693 | ribose phosphate metabolic process | 40.3846 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 40.3846 | 4 | no |
| GO:0022607 | cellular component assembly | 36.5385 | 4 | yes |
| GO:0043933 | protein-containing complex organization | 34.6154 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 32.6923 | 5 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 32.6923 | 5 | no |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 32.6923 | 6 | no |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 32.6923 | 6 | no |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 32.6923 | 7 | no |
| GO:0019752 | carboxylic acid metabolic process | 32.6923 | 5 | no |
| GO:0043436 | oxoacid metabolic process | 32.6923 | 4 | no |
| GO:0046034 | ATP metabolic process | 32.6923 | 7 | no |
| GO:1901362 | organic cyclic compound biosynthetic process | 32.6923 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 30.7692 | 4 | no |
| GO:0072522 | purine-containing compound biosynthetic process | 30.7692 | 5 | no |
| GO:0090407 | organophosphate biosynthetic process | 30.7692 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 28.8462 | 4 | no |
| GO:0006164 | purine nucleotide biosynthetic process | 28.8462 | 6 | no |
| GO:0009152 | purine ribonucleotide biosynthetic process | 28.8462 | 7 | no |
| GO:0009165 | nucleotide biosynthetic process | 28.8462 | 6 | no |
| GO:0009260 | ribonucleotide biosynthetic process | 28.8462 | 6 | no |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 28.8462 | 4 | no |
| GO:0046390 | ribose phosphate biosynthetic process | 28.8462 | 5 | no |
| GO:1901137 | carbohydrate derivative biosynthetic process | 28.8462 | 4 | no |
| GO:1901293 | nucleoside phosphate biosynthetic process | 28.8462 | 5 | no |
| GO:0031323 | regulation of cellular metabolic process | 26.9231 | 4 | no |
| GO:0006996 | organelle organization | 25.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 25.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 25.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 25.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 23.0769 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 23.0769 | 4 | no |
| GO:0010468 | regulation of gene expression | 23.0769 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 23.0769 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 23.0769 | 5 | no |
| GO:0032787 | monocarboxylic acid metabolic process | 23.0769 | 6 | no |
| GO:1901565 | organonitrogen compound catabolic process | 23.0769 | 4 | no |
| GO:0009142 | nucleoside triphosphate biosynthetic process | 23.0769 | 6 | no |
| GO:0009966 | regulation of signal transduction | 21.1538 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 21.1538 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 21.1538 | 4 | no |
| GO:0006754 | ATP biosynthetic process | 21.1538 | 8 | no |
| GO:0009145 | purine nucleoside triphosphate biosynthetic process | 21.1538 | 7 | no |
| GO:0009201 | ribonucleoside triphosphate biosynthetic process | 21.1538 | 7 | no |
| GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 21.1538 | 8 | no |
| GO:0022900 | electron transport chain | 21.1538 | 4 | no |
| GO:0022904 | respiratory electron transport chain | 21.1538 | 5 | no |
| GO:0051259 | protein complex oligomerization | 13.4615 | 6 | yes |
| GO:0051260 | protein homooligomerization | 13.4615 | 7 | yes |
| GO:0051262 | protein tetramerization | 11.5385 | 7 | yes |
| GO:0051289 | protein homotetramerization | 11.5385 | 8 | yes |
| GO:0007600 | sensory perception | 3.8462 | 4 | yes |
| GO:0007601 | visual perception | 3.8462 | 6 | yes |
| GO:0042178 | xenobiotic catabolic process | 3.8462 | 4 | yes |
| GO:0050953 | sensory perception of light stimulus | 3.8462 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| QOR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MD2BP_HUMAN | [view interactions] | High throughput | no | no |
| ZN526_HUMAN | [view interactions] | High throughput | no | yes |
| ASPM_HUMAN | [view interactions] | High throughput | no | no |
| PP6R1_HUMAN | [view interactions] | High throughput | no | no |
| P4R3A_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCH2_HUMAN | [view interactions] | High throughput | no | no |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTR1A_HUMAN | [view interactions] | High throughput | no | no |
| VGFR2_HUMAN | [view interactions] | High throughput | no | no |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| CBX5_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| PPCEL_HUMAN | [view interactions] | High throughput | no | yes |
| MTG2_HUMAN | [view interactions] | High throughput | no | yes |
| MUTA_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF3_HUMAN | [view interactions] | High throughput | no | yes |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF2B3_HUMAN | [view interactions] | High throughput | no | no |
| K1C17_HUMAN | [view interactions] | High throughput | no | no |
| PFKAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| TRXR1_HUMAN | [view interactions] | High throughput | no | yes |
| CAB39_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP2_HUMAN | [view interactions] | High throughput | no | yes |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| DCXR_HUMAN | [view interactions] | High throughput | no | no |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| NNMT_HUMAN | [view interactions] | High throughput | no | no |
| SMAP2_HUMAN | [view interactions] | High throughput | no | yes |
| MTPN_HUMAN | [view interactions] | High throughput | no | yes |
| AL4A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLRX5_HUMAN | [view interactions] | High throughput | no | yes |
| FRDA_HUMAN | [view interactions] | High throughput | no | yes |
| SPRE_HUMAN | [view interactions] | High throughput | no | yes |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| THTM_HUMAN | [view interactions] | High throughput | no | yes |
| LACB2_HUMAN | [view interactions] | High throughput | no | yes |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TBCA_HUMAN | [view interactions] | High throughput | no | yes |
| ACO13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLIC4_HUMAN | [view interactions] | High throughput | no | no |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAP3_HUMAN | [view interactions] | High throughput | no | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KAD2_HUMAN | [view interactions] | High throughput | no | no |
| ALDOC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ETFA_HUMAN | [view interactions] | High throughput | no | yes |
| ETFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA3_HUMAN | [view interactions] | High throughput | no | yes |
| NUD19_HUMAN | [view interactions] | High throughput | no | no |
| PIR_HUMAN | [view interactions] | High throughput | no | no |
| KAD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NQO1_HUMAN | [view interactions] | High throughput | no | no |
| DCTD_HUMAN | [view interactions] | High throughput | no | yes |
| AK1C2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MT1X_HUMAN | [view interactions] | High throughput | no | no |
| SBP1_HUMAN | [view interactions] | High throughput | no | no |
| PTGR1_HUMAN | [view interactions] | High throughput | no | yes |
| TKFC_HUMAN | [view interactions] | High throughput | no | no |
| NIT2_HUMAN | [view interactions] | High throughput | no | yes |
| THIL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACOT1_HUMAN | [view interactions] | High throughput | no | yes |
| ACOT2_HUMAN | [view interactions] | High throughput | no | yes |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATIF1_HUMAN | [view interactions] | High throughput | no | yes |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5J_HUMAN | [view interactions] | High throughput | no | yes |
| ATPF1_HUMAN | [view interactions] | High throughput | no | yes |
| BCS1_HUMAN | [view interactions] | High throughput | no | yes |
| CQ080_HUMAN | [view interactions] | High throughput | no | yes |
| RT29_HUMAN | [view interactions] | High throughput | no | yes |
| ODP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHM_HUMAN | [view interactions] | High throughput | no | yes |
| RNZ2_HUMAN | [view interactions] | High throughput | no | yes |
| GLSK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HINT2_HUMAN | [view interactions] | High throughput | no | yes |
| SYIM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYLM_HUMAN | [view interactions] | High throughput | no | yes |
| LETM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMAB_HUMAN | [view interactions] | High throughput | no | yes |
| RM43_HUMAN | [view interactions] | High throughput | no | no |
| RT10_HUMAN | [view interactions] | High throughput | no | yes |
| RT14_HUMAN | [view interactions] | High throughput | no | yes |
| RT16_HUMAN | [view interactions] | High throughput | no | yes |
| RT17_HUMAN | [view interactions] | High throughput | no | yes |
| RT18B_HUMAN | [view interactions] | High throughput | no | yes |
| RT02_HUMAN | [view interactions] | High throughput | no | no |
| RT22_HUMAN | [view interactions] | High throughput | no | yes |
| RT23_HUMAN | [view interactions] | High throughput | no | yes |
| RT24_HUMAN | [view interactions] | High throughput | no | yes |
| RT25_HUMAN | [view interactions] | High throughput | no | yes |
| RT26_HUMAN | [view interactions] | High throughput | no | yes |
| RT27_HUMAN | [view interactions] | High throughput | no | yes |
| RT28_HUMAN | [view interactions] | High throughput | no | yes |
| RT31_HUMAN | [view interactions] | High throughput | no | yes |
| RT33_HUMAN | [view interactions] | High throughput | no | no |
| RT34_HUMAN | [view interactions] | High throughput | no | yes |
| RT35_HUMAN | [view interactions] | High throughput | no | yes |
| KGD4_HUMAN | [view interactions] | High throughput | no | yes |
| RT05_HUMAN | [view interactions] | High throughput | no | yes |
| RT06_HUMAN | [view interactions] | High throughput | no | yes |
| RT07_HUMAN | [view interactions] | High throughput | no | yes |
| RT09_HUMAN | [view interactions] | High throughput | no | yes |
| IF2M_HUMAN | [view interactions] | High throughput | no | yes |
| NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA6_HUMAN | [view interactions] | High throughput | no | no |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUF4_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS8_HUMAN | [view interactions] | High throughput | no | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV3_HUMAN | [view interactions] | High throughput | no | yes |
| NFL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFS1_HUMAN | [view interactions] | High throughput | no | yes |
| NDKM_HUMAN | [view interactions] | High throughput | no | yes |
| ODO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCNT_HUMAN | [view interactions] | High throughput | no | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDPR_HUMAN | [view interactions] | High throughput | no | yes |
| PPIF_HUMAN | [view interactions] | High throughput | no | no |
| PTCD3_HUMAN | [view interactions] | High throughput | no | yes |
| P5CR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P5CR2_HUMAN | [view interactions] | High throughput | no | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| TACO1_HUMAN | [view interactions] | High throughput | no | yes |
| TIM44_HUMAN | [view interactions] | High throughput | no | yes |
| UBP47_HUMAN | [view interactions] | High throughput | no | yes |
| SYVM_HUMAN | [view interactions] | High throughput | no | yes |
| MET17_HUMAN | [view interactions] | High throughput | no | yes |
| IF3M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1ML_HUMAN | [view interactions] | High throughput | no | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |