LETM1_HUMAN
Evidence for PS localization
Functions
Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion (PubMed). Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (PubMed). Required for the maintenance of the tubular shape and cristae organization (PubMed). In contrast to SLC8B1/NCLX, does not constitute the major factor for mitochondrial calcium extrusion (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 293 | Ile | Asn | Neurodegeneration,childhood-onset,withmultisysteminvolvementduetomitochondrialdysfunction(CONDMIM) | - |
| 294 | Arg | Gln | Neurodegeneration,childhood-onset,withmultisysteminvolvementduetomitochondrialdysfunction(CONDMIM) | - |
| 300 | Pro | Ser | Neurodegeneration,childhood-onset,withmultisysteminvolvementduetomitochondrialdysfunction(CONDMIM) | - |
| 358 | Asp | Asn | Neurodegeneration,childhood-onset,withmultisysteminvolvementduetomitochondrialdysfunction(CONDMIM) | - |
| 587 | Lys | Arg | Neurodegeneration,childhood-onset,withmultisysteminvolvementduetomitochondrialdysfunction(CONDMIM) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in LETM1_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 34.3750 | 4 | no |
| GO:0043168 | anion binding | 34.3750 | 4 | no |
| GO:0003723 | RNA binding | 32.8125 | 4 | no |
| GO:0017076 | purine nucleotide binding | 31.2500 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 26.5625 | 4 | no |
| GO:0043169 | cation binding | 25.0000 | 4 | yes |
| GO:0046872 | metal ion binding | 25.0000 | 5 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.0000 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 20.3125 | 6 | no |
| GO:0016462 | pyrophosphatase activity | 20.3125 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 20.3125 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 20.3125 | 6 | no |
| GO:0008324 | monoatomic cation transmembrane transporter activity | 14.0625 | 4 | yes |
| GO:0022853 | active monoatomic ion transmembrane transporter activity | 14.0625 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 14.0625 | 4 | yes |
| GO:0015078 | proton transmembrane transporter activity | 12.5000 | 5 | yes |
| GO:0005509 | calcium ion binding | 6.2500 | 6 | yes |
| GO:0015085 | calcium ion transmembrane transporter activity | 3.1250 | 6 | yes |
| GO:0043022 | ribosome binding | 3.1250 | 4 | yes |
| GO:0046873 | metal ion transmembrane transporter activity | 3.1250 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in LETM1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 45.3125 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 45.3125 | 4 | no |
| GO:0006996 | organelle organization | 43.7500 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 43.7500 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 43.7500 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 42.1875 | 4 | yes |
| GO:0022607 | cellular component assembly | 37.5000 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 35.9375 | 4 | no |
| GO:0010468 | regulation of gene expression | 35.9375 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 35.9375 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 35.9375 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 35.9375 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 34.3750 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.3750 | 5 | no |
| GO:0010646 | regulation of cell communication | 34.3750 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.8125 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 28.1250 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 28.1250 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 28.1250 | 4 | no |
| GO:0008104 | protein localization | 26.5625 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.5625 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 26.5625 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 26.5625 | 5 | no |
| GO:0071702 | organic substance transport | 26.5625 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 25.0000 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 25.0000 | 5 | no |
| GO:0023057 | negative regulation of signaling | 25.0000 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 25.0000 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 23.4375 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.4375 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 23.4375 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.4375 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.4375 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.4375 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 23.4375 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.4375 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 23.4375 | 6 | no |
| GO:0071705 | nitrogen compound transport | 23.4375 | 4 | no |
| GO:0043933 | protein-containing complex organization | 21.8750 | 4 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 21.8750 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 21.8750 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 20.3125 | 5 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 20.3125 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.3125 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 20.3125 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 20.3125 | 5 | no |
| GO:0023056 | positive regulation of signaling | 20.3125 | 4 | no |
| GO:0051049 | regulation of transport | 20.3125 | 4 | no |
| GO:0080134 | regulation of response to stress | 17.1875 | 4 | yes |
| GO:0006873 | intracellular monoatomic ion homeostasis | 12.5000 | 4 | yes |
| GO:0007005 | mitochondrion organization | 12.5000 | 5 | yes |
| GO:0030003 | intracellular monoatomic cation homeostasis | 12.5000 | 5 | yes |
| GO:0055080 | monoatomic cation homeostasis | 12.5000 | 4 | yes |
| GO:0061024 | membrane organization | 12.5000 | 4 | yes |
| GO:0006811 | monoatomic ion transport | 9.3750 | 4 | yes |
| GO:0006812 | monoatomic cation transport | 7.8125 | 5 | yes |
| GO:0006839 | mitochondrial transport | 7.8125 | 4 | yes |
| GO:0006874 | intracellular calcium ion homeostasis | 6.2500 | 5 | yes |
| GO:0051259 | protein complex oligomerization | 6.2500 | 6 | yes |
| GO:0051260 | protein homooligomerization | 6.2500 | 7 | yes |
| GO:0055074 | calcium ion homeostasis | 6.2500 | 4 | yes |
| GO:0098655 | monoatomic cation transmembrane transport | 6.2500 | 4 | yes |
| GO:0098662 | inorganic cation transmembrane transport | 6.2500 | 4 | yes |
| GO:0007006 | mitochondrial membrane organization | 4.6875 | 5 | yes |
| GO:0007007 | inner mitochondrial membrane organization | 4.6875 | 6 | yes |
| GO:0030001 | metal ion transport | 4.6875 | 6 | yes |
| GO:0080135 | regulation of cellular response to stress | 4.6875 | 4 | yes |
| GO:0006816 | calcium ion transport | 3.1250 | 7 | yes |
| GO:0042407 | cristae formation | 3.1250 | 7 | yes |
| GO:0070588 | calcium ion transmembrane transport | 3.1250 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| BCS1_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI33_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FITM2_HUMAN | [view interactions] | High throughput | no | no |
| ATG7_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| C10_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACOT9_HUMAN | [view interactions] | High throughput | no | yes |
| ODO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADAS_HUMAN | [view interactions] | High throughput | no | yes |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| MCAT_HUMAN | [view interactions] | High throughput | no | yes |
| APOE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCPDL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PREB_HUMAN | [view interactions] | High throughput | no | yes |
| NB5R1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASPH_HUMAN | [view interactions] | High throughput | no | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MRM1_HUMAN | [view interactions] | High throughput | no | no |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| GRSF1_HUMAN | [view interactions] | High throughput | no | yes |
| ACAD9_HUMAN | [view interactions] | High throughput | no | yes |
| AUHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTRFR_HUMAN | [view interactions] | High throughput | no | yes |
| CQ080_HUMAN | [view interactions] | High throughput | no | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | no |
| MRES1_HUMAN | [view interactions] | High throughput | no | yes |
| CH082_HUMAN | [view interactions] | High throughput | no | yes |
| MCUR1_HUMAN | [view interactions] | High throughput | no | no |
| CC90B_HUMAN | [view interactions] | High throughput | no | yes |
| CHCH1_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| QOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX28_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD2_HUMAN | [view interactions] | High throughput | no | no |
| FAKD3_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD5_HUMAN | [view interactions] | High throughput | no | yes |
| EFGM_HUMAN | [view interactions] | High throughput | no | yes |
| RRF2M_HUMAN | [view interactions] | High throughput | no | yes |
| HINT2_HUMAN | [view interactions] | High throughput | no | yes |
| LONM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCU_HUMAN | [view interactions] | High throughput | no | yes |
| MCUB_HUMAN | [view interactions] | High throughput | no | no |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET15_HUMAN | [view interactions] | High throughput | no | no |
| MET17_HUMAN | [view interactions] | High throughput | no | yes |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM11_HUMAN | [view interactions] | High throughput | no | yes |
| RT12_HUMAN | [view interactions] | High throughput | no | yes |
| RT26_HUMAN | [view interactions] | High throughput | no | yes |
| RRFM_HUMAN | [view interactions] | High throughput | no | yes |
| MTEF3_HUMAN | [view interactions] | High throughput | no | no |
| FMT_HUMAN | [view interactions] | High throughput | no | yes |
| MTG1_HUMAN | [view interactions] | High throughput | no | yes |
| MTG2_HUMAN | [view interactions] | High throughput | no | yes |
| IF2M_HUMAN | [view interactions] | High throughput | no | yes |
| IF3M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1ML_HUMAN | [view interactions] | High throughput | no | yes |
| NGRN_HUMAN | [view interactions] | High throughput | no | yes |
| OTC_HUMAN | [view interactions] | High throughput | no | no |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| MPPB_HUMAN | [view interactions] | High throughput | no | yes |
| RMND1_HUMAN | [view interactions] | High throughput | no | yes |
| RUSD3_HUMAN | [view interactions] | High throughput | no | yes |
| RUSD4_HUMAN | [view interactions] | High throughput | no | yes |
| S2551_HUMAN | [view interactions] | High throughput | no | no |
| SLIRP_HUMAN | [view interactions] | High throughput | no | yes |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SURF1_HUMAN | [view interactions] | High throughput | no | yes |
| TACO1_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| TEFM_HUMAN | [view interactions] | High throughput | no | no |
| TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM29_HUMAN | [view interactions] | High throughput | no | no |
| TMM70_HUMAN | [view interactions] | High throughput | no | yes |
| TRUB2_HUMAN | [view interactions] | High throughput | no | yes |
| EFTS_HUMAN | [view interactions] | High throughput | no | no |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VWA8_HUMAN | [view interactions] | High throughput | no | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC15_HUMAN | [view interactions] | High throughput | no | no |
| TIM14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC28_HUMAN | [view interactions] | High throughput | no | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYAM_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| TBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LATS2_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| SNR27_HUMAN | [view interactions] | High throughput | no | yes |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RN19B_HUMAN | [view interactions] | High throughput | no | yes |
| UBP47_HUMAN | [view interactions] | High throughput | no | yes |
| 3BHS2_HUMAN | [view interactions] | High throughput | no | no |
| CP1A1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| MAIP1_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PPM1A_HUMAN | [view interactions] | High throughput | no | yes |
| PEPL_HUMAN | [view interactions] | High throughput | no | yes |
| CALR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| SGK1_HUMAN | [view interactions] | High throughput | no | yes |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| ZNF76_HUMAN | [view interactions] | High throughput | no | no |
| KRA62_HUMAN | [view interactions] | High throughput | no | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AKIP_HUMAN | [view interactions] | High throughput | no | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX14_HUMAN | [view interactions] | High throughput | no | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDK1_HUMAN | [view interactions] | High throughput | no | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TR61B_HUMAN | [view interactions] | High throughput | no | yes |
| IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
| HTRA2_HUMAN | [view interactions] | High throughput | no | yes |
| IMP1L_HUMAN | [view interactions] | High throughput | no | yes |
| LACTB_HUMAN | [view interactions] | High throughput | no | yes |
| OMA1_HUMAN | [view interactions] | High throughput | no | no |
| PARL_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PCDGG_HUMAN | [view interactions] | High throughput | no | no |
| RT11_HUMAN | [view interactions] | High throughput | no | yes |
| LYPD4_HUMAN | [view interactions] | High throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLC14_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| CENPM_HUMAN | [view interactions] | High throughput | no | yes |
| F234A_HUMAN | [view interactions] | High throughput | no | yes |
| RCL1_HUMAN | [view interactions] | High throughput | no | no |
| HYPM_HUMAN | [view interactions] | High throughput | no | no |
| FRIL_HUMAN | [view interactions] | High throughput | no | yes |
| CART_HUMAN | [view interactions] | High throughput | no | yes |
| GSX1_HUMAN | [view interactions] | High throughput | no | no |
| RL35A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MSS4_HUMAN | [view interactions] | High throughput | no | yes |
| LR14B_HUMAN | [view interactions] | High throughput | no | no |
| FSD2_HUMAN | [view interactions] | High throughput | no | no |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| TTMP_HUMAN | [view interactions] | High throughput | no | no |
| MLC1_HUMAN | [view interactions] | High throughput | no | no |
| O2T10_HUMAN | [view interactions] | High throughput | no | no |
| CRYAA_HUMAN | [view interactions] | High throughput | no | no |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| SERB1_HUMAN | [view interactions] | High throughput | no | yes |
| RTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| UB2Q2_HUMAN | [view interactions] | High throughput | no | no |
| ICE2_HUMAN | [view interactions] | High throughput | no | no |
| TIDC1_HUMAN | [view interactions] | High throughput | no | yes |
| TRML2_HUMAN | [view interactions] | High throughput | no | no |
| T183A_HUMAN | [view interactions] | High throughput | no | no |
| MND1_HUMAN | [view interactions] | High throughput | no | no |
| DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSGEP_HUMAN | [view interactions] | High throughput | no | yes |
| CDKAL_HUMAN | [view interactions] | High throughput | no | no |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| NTNG1_HUMAN | [view interactions] | High throughput | no | no |
| CBCO1_HUMAN | [view interactions] | High throughput | no | no |
| DNAL4_HUMAN | [view interactions] | High throughput | no | yes |
| SYT6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CEP43_HUMAN | [view interactions] | High throughput | no | no |
| PEX19_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WIF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| CLIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| HEAT3_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RER1_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| RBCC1_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK7_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |