PRDX6_HUMAN
Evidence for PS localization
Functions
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (PubMed, PubMed). Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides (PubMed). Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity) (PubMed, PubMed). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH (PubMed). Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis (PubMed). Exhibits acyl-CoA-dependent lysophospholipid acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (PubMed). Shows a clear preference for LPC as the lysophospholipid and for palmitoyl CoA as the fatty acyl substrate (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
No data found.
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PRDX6_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 32.1429 | 4 | no |
| GO:0043169 | cation binding | 29.7619 | 4 | no |
| GO:0000166 | nucleotide binding | 29.7619 | 4 | no |
| GO:0046872 | metal ion binding | 28.5714 | 5 | no |
| GO:0017076 | purine nucleotide binding | 28.5714 | 5 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 25.0000 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 25.0000 | 6 | no |
| GO:0003723 | RNA binding | 25.0000 | 4 | no |
| GO:0031625 | ubiquitin protein ligase binding | 23.8095 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 22.6190 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 21.4286 | 4 | no |
| GO:0045296 | cadherin binding | 19.0476 | 4 | yes |
| GO:0004620 | phospholipase activity | 4.7619 | 5 | yes |
| GO:0016298 | lipase activity | 4.7619 | 4 | yes |
| GO:0052689 | carboxylic ester hydrolase activity | 4.7619 | 4 | yes |
| GO:0004623 | phospholipase A2 activity | 3.5714 | 5 | yes |
| GO:0008374 | O-acyltransferase activity | 3.5714 | 5 | yes |
| GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | 3.5714 | 4 | yes |
| GO:0047499 | calcium-independent phospholipase A2 activity | 3.5714 | 6 | yes |
| GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity | 2.3810 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PRDX6_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 52.3810 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 51.1905 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 47.6190 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 46.4286 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 44.0476 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 44.0476 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 42.8571 | 5 | yes |
| GO:0010468 | regulation of gene expression | 41.6667 | 6 | yes |
| GO:0009893 | positive regulation of metabolic process | 40.4762 | 4 | yes |
| GO:0010646 | regulation of cell communication | 40.4762 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 38.0952 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.9048 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 36.9048 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 35.7143 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 35.7143 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 34.5238 | 5 | yes |
| GO:0051128 | regulation of cellular component organization | 34.5238 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 34.5238 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 33.3333 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.1429 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 32.1429 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 30.9524 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 30.9524 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 30.9524 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 29.7619 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 29.7619 | 6 | yes |
| GO:0042981 | regulation of apoptotic process | 29.7619 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 29.7619 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 28.5714 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 28.5714 | 6 | no |
| GO:0080134 | regulation of response to stress | 28.5714 | 4 | no |
| GO:0006996 | organelle organization | 26.1905 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 26.1905 | 6 | no |
| GO:0031399 | regulation of protein modification process | 26.1905 | 6 | no |
| GO:0043412 | macromolecule modification | 26.1905 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.1905 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 26.1905 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.1905 | 6 | no |
| GO:0051049 | regulation of transport | 26.1905 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 26.1905 | 5 | no |
| GO:0036211 | protein modification process | 25.0000 | 4 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 25.0000 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 23.8095 | 7 | yes |
| GO:0008104 | protein localization | 23.8095 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 23.8095 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 23.8095 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 23.8095 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.8095 | 4 | no |
| GO:0023057 | negative regulation of signaling | 23.8095 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 23.8095 | 4 | no |
| GO:0009894 | regulation of catabolic process | 23.8095 | 4 | no |
| GO:0033043 | regulation of organelle organization | 23.8095 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 23.8095 | 6 | no |
| GO:0022607 | cellular component assembly | 22.6190 | 4 | no |
| GO:0043069 | negative regulation of programmed cell death | 22.6190 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 22.6190 | 4 | no |
| GO:0071310 | cellular response to organic substance | 22.6190 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 21.4286 | 5 | yes |
| GO:0009967 | positive regulation of signal transduction | 21.4286 | 5 | no |
| GO:0043066 | negative regulation of apoptotic process | 21.4286 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 20.2381 | 7 | no |
| GO:0045595 | regulation of cell differentiation | 20.2381 | 4 | no |
| GO:0006753 | nucleoside phosphate metabolic process | 20.2381 | 4 | no |
| GO:0009117 | nucleotide metabolic process | 20.2381 | 5 | no |
| GO:0019752 | carboxylic acid metabolic process | 20.2381 | 5 | no |
| GO:0043436 | oxoacid metabolic process | 20.2381 | 4 | no |
| GO:0032101 | regulation of response to external stimulus | 20.2381 | 4 | no |
| GO:0060341 | regulation of cellular localization | 20.2381 | 4 | no |
| GO:0051254 | positive regulation of RNA metabolic process | 19.0476 | 6 | yes |
| GO:0046434 | organophosphate catabolic process | 10.7143 | 4 | yes |
| GO:0016042 | lipid catabolic process | 8.3333 | 4 | yes |
| GO:0006644 | phospholipid metabolic process | 7.1429 | 4 | yes |
| GO:0006650 | glycerophospholipid metabolic process | 5.9524 | 5 | yes |
| GO:0044242 | cellular lipid catabolic process | 5.9524 | 4 | yes |
| GO:0046486 | glycerolipid metabolic process | 5.9524 | 4 | yes |
| GO:0009395 | phospholipid catabolic process | 4.7619 | 5 | yes |
| GO:0043484 | regulation of RNA splicing | 4.7619 | 6 | yes |
| GO:0046475 | glycerophospholipid catabolic process | 4.7619 | 6 | yes |
| GO:0046503 | glycerolipid catabolic process | 4.7619 | 5 | yes |
| GO:0033120 | positive regulation of RNA splicing | 3.5714 | 7 | yes |
| GO:0048024 | regulation of mRNA splicing, via spliceosome | 3.5714 | 7 | yes |
| GO:0050684 | regulation of mRNA processing | 3.5714 | 7 | yes |
| GO:1903311 | regulation of mRNA metabolic process | 3.5714 | 6 | yes |
| GO:0048026 | positive regulation of mRNA splicing, via spliceosome | 2.3810 | 8 | yes |
| GO:0050685 | positive regulation of mRNA processing | 2.3810 | 8 | yes |
| GO:1903313 | positive regulation of mRNA metabolic process | 2.3810 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRDX6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCF2_HUMAN | [view interactions] | Low throughput | no | no |
| GSTP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CASPA_HUMAN | [view interactions] | Low throughput | no | yes |
| STH_HUMAN | [view interactions] | Low throughput | no | no |
| F168B_HUMAN | [view interactions] | Low throughput | no | yes |
| APEX1_HUMAN | [view interactions] | Low throughput | no | yes |
| CASP8_HUMAN | [view interactions] | Low throughput | no | yes |
| SFTA1_HUMAN | [view interactions] | Low throughput | no | no |
| SFPA2_HUMAN | [view interactions] | Low throughput | no | no |
| ARNT_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| CTBP2_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| MARH6_HUMAN | [view interactions] | High throughput | no | yes |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RCAN3_HUMAN | [view interactions] | High throughput | no | no |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCL6_HUMAN | [view interactions] | High throughput | no | no |
| BACH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOLR1_HUMAN | [view interactions] | High throughput | no | no |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E2F4_HUMAN | [view interactions] | High throughput | no | no |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CDK7_HUMAN | [view interactions] | High throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASXL1_HUMAN | [view interactions] | High throughput | no | no |
| ASXL2_HUMAN | [view interactions] | High throughput | no | no |
| ASXL3_HUMAN | [view interactions] | High throughput | no | no |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| TET5C_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN149_HUMAN | [view interactions] | High throughput | no | no |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL5_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAVN1_HUMAN | [view interactions] | High throughput | no | no |
| CAVN2_HUMAN | [view interactions] | High throughput | no | no |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM9_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUCB2_HUMAN | [view interactions] | High throughput | no | no |
| SMAP_HUMAN | [view interactions] | High throughput | no | yes |
| NIT2_HUMAN | [view interactions] | High throughput | no | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDHC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PREP_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| PDES1_HUMAN | [view interactions] | High throughput | no | no |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| PUR4_HUMAN | [view interactions] | High throughput | no | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSU72_HUMAN | [view interactions] | High throughput | no | yes |
| ALDR_HUMAN | [view interactions] | High throughput | no | no |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| CD2AP_HUMAN | [view interactions] | High throughput | no | no |
| ECI1_HUMAN | [view interactions] | High throughput | no | yes |
| LGUL_HUMAN | [view interactions] | High throughput | no | yes |
| G6PI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRHPR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SCOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK054_HUMAN | [view interactions] | High throughput | no | no |
| CAPG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ENOPH_HUMAN | [view interactions] | High throughput | no | yes |
| GSTO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAAI_HUMAN | [view interactions] | High throughput | no | yes |
| HINT1_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYPA1_HUMAN | [view interactions] | High throughput | no | yes |
| PGM1_HUMAN | [view interactions] | High throughput | no | no |
| PTGR1_HUMAN | [view interactions] | High throughput | no | yes |
| RISC_HUMAN | [view interactions] | High throughput | no | yes |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| SPB5_HUMAN | [view interactions] | High throughput | no | no |
| SPRE_HUMAN | [view interactions] | High throughput | no | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABHDB_HUMAN | [view interactions] | High throughput | no | yes |
| LACB2_HUMAN | [view interactions] | High throughput | no | yes |
| AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLRX5_HUMAN | [view interactions] | High throughput | no | yes |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| KGUA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FRDA_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | no |
| CLIC4_HUMAN | [view interactions] | High throughput | no | no |
| QOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTRD1_HUMAN | [view interactions] | High throughput | no | yes |
| MTPN_HUMAN | [view interactions] | High throughput | no | yes |
| TBCA_HUMAN | [view interactions] | High throughput | no | yes |
| CLIC1_HUMAN | [view interactions] | High throughput | no | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADX_HUMAN | [view interactions] | High throughput | no | no |
| GCSH_HUMAN | [view interactions] | High throughput | no | yes |
| ACPM_HUMAN | [view interactions] | High throughput | no | yes |
| 6PGL_HUMAN | [view interactions] | High throughput | no | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COA7_HUMAN | [view interactions] | High throughput | no | yes |
| HINT2_HUMAN | [view interactions] | High throughput | no | yes |
| IDHP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NENF_HUMAN | [view interactions] | High throughput | no | yes |
| PDP1_HUMAN | [view interactions] | High throughput | no | yes |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPDM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPC2_HUMAN | [view interactions] | High throughput | no | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| GLRX2_HUMAN | [view interactions] | High throughput | no | yes |
| RT4I1_HUMAN | [view interactions] | High throughput | no | yes |
| PA24A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUFU_HUMAN | [view interactions] | High throughput | no | yes |
| NQO1_HUMAN | [view interactions] | High throughput | no | no |
| NCOA3_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AL7A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| A1AG2_HUMAN | [view interactions] | High throughput | no | no |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| S10A9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| MK13_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| RAD52_HUMAN | [view interactions] | High throughput | no | no |
| CAVN3_HUMAN | [view interactions] | High throughput | no | no |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDKA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| PCDH7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXO1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA4_HUMAN | [view interactions] | High throughput | no | yes |
| WWTR1_HUMAN | [view interactions] | High throughput | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOAT1_HUMAN | [view interactions] | High throughput | no | no |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| PPTC7_HUMAN | [view interactions] | High throughput | no | yes |
| PHOP1_HUMAN | [view interactions] | High throughput | no | no |
| ACK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYLK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| CDKL3_HUMAN | [view interactions] | High throughput | no | no |
| NEK7_HUMAN | [view interactions] | High throughput | no | yes |
| SGK3_HUMAN | [view interactions] | High throughput | no | yes |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPSP_HUMAN | [view interactions] | High throughput | no | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD8_HUMAN | [view interactions] | High throughput | no | yes |
| ARFG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| TIFAB_HUMAN | [view interactions] | High throughput | no | no |
| KATIP_HUMAN | [view interactions] | High throughput | no | yes |
| TE2IP_HUMAN | [view interactions] | High throughput | no | yes |
| DYRK2_HUMAN | [view interactions] | High throughput | no | yes |
| RARA_HUMAN | [view interactions] | High throughput | no | no |
| PPARD_HUMAN | [view interactions] | High throughput | no | yes |
| HNF4G_HUMAN | [view interactions] | High throughput | no | no |
| PAXI1_HUMAN | [view interactions] | High throughput | no | no |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASB3_HUMAN | [view interactions] | High throughput | no | yes |
| ASB12_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DS13A_HUMAN | [view interactions] | High throughput | no | no |
| DUS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |