Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RNF10_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Transcriptional factor involved in the regulation of MAG (Myelin-associated glycoprotein) expression. Acts as a regulator of Schwann cell differentiation and myelination. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in RNF10_HUMAN
GO:0003723 RNA binding 55.1724 4 no
GO:0043169 cation binding 34.4828 4 yes
GO:0046872 metal ion binding 34.4828 5 yes
GO:0043168 anion binding 31.0345 4 no
GO:0000166 nucleotide binding 24.1379 4 no
GO:0017076 purine nucleotide binding 24.1379 5 no
GO:0032555 purine ribonucleotide binding 24.1379 4 no
GO:0035639 purine ribonucleoside triphosphate binding 24.1379 4 no
GO:0042803 protein homodimerization activity 24.1379 4 no
GO:0019900 kinase binding 20.6897 4 no
GO:0019901 protein kinase binding 20.6897 5 no
GO:0031625 ubiquitin protein ligase binding 20.6897 5 no
GO:0044389 ubiquitin-like protein ligase binding 20.6897 4 no
GO:0045296 cadherin binding 20.6897 4 no
GO:0000976 transcription cis-regulatory region binding 10.3448 5 yes
GO:0001067 transcription regulatory region nucleic acid binding 10.3448 4 yes
GO:0003677 DNA binding 10.3448 4 yes
GO:0003690 double-stranded DNA binding 10.3448 5 yes
GO:0016755 aminoacyltransferase activity 10.3448 4 yes
GO:0043565 sequence-specific DNA binding 10.3448 5 yes
GO:1990837 sequence-specific double-stranded DNA binding 10.3448 6 yes
GO:0004842 ubiquitin-protein transferase activity 6.8966 4 yes
GO:0061630 ubiquitin protein ligase activity 6.8966 5 yes
GO:0061659 ubiquitin-like protein ligase activity 6.8966 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RNF10_HUMAN
GO:0048522 positive regulation of cellular process 79.3103 4 yes
GO:0060255 regulation of macromolecule metabolic process 72.4138 4 yes
GO:0080090 regulation of primary metabolic process 72.4138 4 yes
GO:0031323 regulation of cellular metabolic process 65.5172 4 yes
GO:0051246 regulation of protein metabolic process 62.0690 5 no
GO:0009889 regulation of biosynthetic process 55.1724 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 55.1724 5 yes
GO:0031326 regulation of cellular biosynthetic process 55.1724 5 yes
GO:0009893 positive regulation of metabolic process 51.7241 4 yes
GO:0010468 regulation of gene expression 51.7241 6 yes
GO:0010646 regulation of cell communication 51.7241 4 no
GO:0010604 positive regulation of macromolecule metabolic process 48.2759 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 48.2759 5 yes
GO:0048523 negative regulation of cellular process 48.2759 4 yes
GO:0051049 regulation of transport 48.2759 4 no
GO:0051128 regulation of cellular component organization 48.2759 4 no
GO:0031325 positive regulation of cellular metabolic process 41.3793 5 yes
GO:0051252 regulation of RNA metabolic process 41.3793 5 yes
GO:0009966 regulation of signal transduction 41.3793 4 no
GO:0048584 positive regulation of response to stimulus 41.3793 4 no
GO:0008104 protein localization 41.3793 4 no
GO:0009892 negative regulation of metabolic process 41.3793 4 no
GO:0010605 negative regulation of macromolecule metabolic process 41.3793 5 no
GO:0006355 regulation of DNA-templated transcription 37.9310 7 yes
GO:2001141 regulation of RNA biosynthetic process 37.9310 6 yes
GO:0031399 regulation of protein modification process 37.9310 6 no
GO:0051247 positive regulation of protein metabolic process 37.9310 6 no
GO:0022607 cellular component assembly 37.9310 4 no
GO:0030162 regulation of proteolysis 37.9310 6 no
GO:0031324 negative regulation of cellular metabolic process 37.9310 5 no
GO:0071702 organic substance transport 37.9310 4 no
GO:0071705 nitrogen compound transport 37.9310 4 no
GO:0009891 positive regulation of biosynthetic process 34.4828 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 34.4828 6 yes
GO:0009894 regulation of catabolic process 34.4828 4 no
GO:0019220 regulation of phosphate metabolic process 34.4828 6 no
GO:0051174 regulation of phosphorus metabolic process 34.4828 5 no
GO:0032880 regulation of protein localization 34.4828 5 no
GO:0042981 regulation of apoptotic process 34.4828 5 no
GO:0043067 regulation of programmed cell death 34.4828 4 no
GO:0051050 positive regulation of transport 34.4828 4 no
GO:0060341 regulation of cellular localization 34.4828 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 31.0345 6 yes
GO:1902531 regulation of intracellular signal transduction 31.0345 5 no
GO:0009890 negative regulation of biosynthetic process 31.0345 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 31.0345 6 no
GO:0031327 negative regulation of cellular biosynthetic process 31.0345 6 no
GO:0051248 negative regulation of protein metabolic process 31.0345 6 no
GO:0006996 organelle organization 31.0345 4 no
GO:0015031 protein transport 31.0345 4 no
GO:0042176 regulation of protein catabolic process 27.5862 5 no
GO:0042325 regulation of phosphorylation 27.5862 7 no
GO:0051338 regulation of transferase activity 27.5862 4 no
GO:0010647 positive regulation of cell communication 27.5862 5 no
GO:0023056 positive regulation of signaling 27.5862 4 no
GO:0080134 regulation of response to stress 27.5862 4 no
GO:0043066 negative regulation of apoptotic process 27.5862 6 no
GO:0043069 negative regulation of programmed cell death 27.5862 5 no
GO:0043933 protein-containing complex organization 27.5862 4 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 27.5862 5 no
GO:0051253 negative regulation of RNA metabolic process 27.5862 6 no
GO:0070201 regulation of establishment of protein localization 27.5862 6 no
GO:1903829 positive regulation of protein localization 27.5862 5 no
GO:0006357 regulation of transcription by RNA polymerase II 24.1379 8 yes
GO:0036211 protein modification process 24.1379 4 yes
GO:0043412 macromolecule modification 24.1379 4 yes
GO:0043549 regulation of kinase activity 24.1379 5 no
GO:0031401 positive regulation of protein modification process 24.1379 7 no
GO:0090304 nucleic acid metabolic process 24.1379 4 no
GO:0033365 protein localization to organelle 24.1379 5 no
GO:0045862 positive regulation of proteolysis 24.1379 7 no
GO:0045892 negative regulation of DNA-templated transcription 24.1379 8 no
GO:0051094 positive regulation of developmental process 24.1379 4 no
GO:0051223 regulation of protein transport 24.1379 5 no
GO:0065003 protein-containing complex assembly 24.1379 5 no
GO:1902679 negative regulation of RNA biosynthetic process 24.1379 7 no
GO:0006886 intracellular protein transport 24.1379 4 no
GO:0050804 modulation of chemical synaptic transmission 24.1379 5 no
GO:0051130 positive regulation of cellular component organization 24.1379 5 no
GO:0099177 regulation of trans-synaptic signaling 24.1379 4 no
GO:0001932 regulation of protein phosphorylation 24.1379 7 no
GO:0010959 regulation of metal ion transport 24.1379 6 no
GO:0043269 regulation of monoatomic ion transport 24.1379 5 no
GO:0009057 macromolecule catabolic process 20.6897 4 yes
GO:0042127 regulation of cell population proliferation 20.6897 4 yes
GO:0044057 regulation of system process 20.6897 4 yes
GO:0045595 regulation of cell differentiation 20.6897 4 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 20.6897 5 yes
GO:0051240 positive regulation of multicellular organismal process 20.6897 4 yes
GO:1901565 organonitrogen compound catabolic process 20.6897 4 yes
GO:2000026 regulation of multicellular organismal development 20.6897 4 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 20.6897 9 no
GO:0009896 positive regulation of catabolic process 20.6897 5 no
GO:0009968 negative regulation of signal transduction 20.6897 5 no
GO:0010648 negative regulation of cell communication 20.6897 5 no
GO:0023057 negative regulation of signaling 20.6897 4 no
GO:0031344 regulation of cell projection organization 20.6897 5 no
GO:0032386 regulation of intracellular transport 20.6897 5 no
GO:0033157 regulation of intracellular protein transport 20.6897 6 no
GO:0046822 regulation of nucleocytoplasmic transport 20.6897 6 no
GO:0048585 negative regulation of response to stimulus 20.6897 4 no
GO:0051726 regulation of cell cycle 20.6897 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 20.6897 6 no
GO:1903050 regulation of proteolysis involved in protein catabolic process 20.6897 7 no
GO:1904951 positive regulation of establishment of protein localization 20.6897 6 no
GO:0010562 positive regulation of phosphorus metabolic process 20.6897 6 no
GO:0043085 positive regulation of catalytic activity 20.6897 4 no
GO:0044087 regulation of cellular component biogenesis 20.6897 4 no
GO:0045859 regulation of protein kinase activity 20.6897 6 no
GO:0045937 positive regulation of phosphate metabolic process 20.6897 7 no
GO:0051924 regulation of calcium ion transport 20.6897 7 no
GO:0043687 post-translational protein modification 17.2414 5 yes
GO:0070647 protein modification by small protein conjugation or removal 17.2414 6 yes
GO:0006508 proteolysis 13.7931 4 yes
GO:0006511 ubiquitin-dependent protein catabolic process 13.7931 7 yes
GO:0019941 modification-dependent protein catabolic process 13.7931 6 yes
GO:0030163 protein catabolic process 13.7931 4 yes
GO:0032446 protein modification by small protein conjugation 13.7931 7 yes
GO:0043632 modification-dependent macromolecule catabolic process 13.7931 5 yes
GO:0051603 proteolysis involved in protein catabolic process 13.7931 5 yes
GO:0051960 regulation of nervous system development 13.7931 5 yes
GO:0008285 negative regulation of cell population proliferation 10.3448 5 yes
GO:0016567 protein ubiquitination 10.3448 8 yes
GO:0045893 positive regulation of DNA-templated transcription 10.3448 8 yes
GO:0050767 regulation of neurogenesis 10.3448 6 yes
GO:0051241 negative regulation of multicellular organismal process 10.3448 4 yes
GO:0051254 positive regulation of RNA metabolic process 10.3448 6 yes
GO:0060284 regulation of cell development 10.3448 5 yes
GO:1902680 positive regulation of RNA biosynthetic process 10.3448 7 yes
GO:0010498 proteasomal protein catabolic process 6.8966 5 yes
GO:0010721 negative regulation of cell development 6.8966 6 yes
GO:0031644 regulation of nervous system process 6.8966 5 yes
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 6.8966 6 yes
GO:0045596 negative regulation of cell differentiation 6.8966 5 yes
GO:0050768 negative regulation of neurogenesis 6.8966 6 yes
GO:0051093 negative regulation of developmental process 6.8966 4 yes
GO:0051865 protein autoubiquitination 6.8966 9 yes
GO:0051961 negative regulation of nervous system development 6.8966 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
RASF1_HUMAN [view interactions] Low throughput no yes
MEOX2_HUMAN [view interactions] Low throughput no no
UBTD1_HUMAN [view interactions] Low throughput no no
MYLK_HUMAN [view entry] [view interactions] High throughput yes no
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
UB2D1_HUMAN [view interactions] High throughput no yes
UB2D2_HUMAN [view interactions] High throughput no yes
KDM1A_HUMAN [view interactions] High throughput no yes
MIS12_HUMAN [view interactions] High throughput no yes
CD2AP_HUMAN [view interactions] High throughput no no
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
TERF1_HUMAN [view interactions] High throughput no no
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
UB2D3_HUMAN [view interactions] High throughput no yes
UB2E1_HUMAN [view interactions] High throughput no yes
UBC9_HUMAN [view entry] [view interactions] High throughput yes yes
UB2E3_HUMAN [view interactions] High throughput no yes
UB2D4_HUMAN [view interactions] High throughput no yes
UBE2O_HUMAN [view interactions] High throughput no yes
UB2E2_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
UB2V1_HUMAN [view entry] [view interactions] High throughput yes no
UBE2W_HUMAN [view interactions] High throughput no yes
UB2Q2_HUMAN [view interactions] High throughput no no
UBE2U_HUMAN [view interactions] High throughput no no
MDM2_HUMAN [view entry] [view interactions] High throughput yes yes
TRI26_HUMAN [view interactions] High throughput no yes
CASP6_HUMAN [view interactions] High throughput no no
HIP1_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
RAN_HUMAN [view entry] [view interactions] High throughput yes no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
RNF11_HUMAN [view interactions] High throughput no yes
COQ8A_HUMAN [view interactions] High throughput no no
SPRE1_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
TADBP_HUMAN [view interactions] High throughput no yes
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
SETB1_HUMAN [view interactions] High throughput no yes
TLE1_HUMAN [view interactions] High throughput no yes
CC90B_HUMAN [view interactions] High throughput no yes
RIF1_HUMAN [view interactions] High throughput no yes
UT14A_HUMAN [view interactions] High throughput no yes
CO4A5_HUMAN [view interactions] High throughput no no
DYSF_HUMAN [view interactions] High throughput no no
TULP3_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
DSCR9_HUMAN [view interactions] High throughput no no
BTG3_HUMAN [view interactions] High throughput no yes
PCNA_HUMAN [view interactions] High throughput no no
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
CSTN1_HUMAN [view entry] [view interactions] High throughput yes yes
TRI55_HUMAN [view interactions] High throughput no no
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
LRIF1_HUMAN [view interactions] High throughput no yes
UB2J2_HUMAN [view interactions] High throughput no no
TRI63_HUMAN [view interactions] High throughput no no
RSPH1_HUMAN [view interactions] High throughput no no
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
RC3H1_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
TBCC1_HUMAN [view interactions] High throughput no no
HAUS3_HUMAN [view interactions] High throughput no yes
HAUS4_HUMAN [view interactions] High throughput no yes
NCOA4_HUMAN [view interactions] High throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
HAUS8_HUMAN [view interactions] High throughput no yes
HAUS7_HUMAN [view interactions] High throughput no no
HAUS6_HUMAN [view interactions] High throughput no yes
CEP43_HUMAN [view interactions] High throughput no no
LRP5_HUMAN [view interactions] High throughput no yes
HAUS1_HUMAN [view interactions] High throughput no yes
PDLI7_HUMAN [view entry] [view interactions] High throughput yes no
HAUS2_HUMAN [view interactions] High throughput no yes
DCAF5_HUMAN [view interactions] High throughput no yes
CATL2_HUMAN [view interactions] High throughput no yes
CE350_HUMAN [view interactions] High throughput no yes
HAUS5_HUMAN [view interactions] High throughput no yes
P2R3B_HUMAN [view interactions] High throughput no no
ARI1B_HUMAN [view interactions] High throughput no yes
DDX23_HUMAN [view interactions] High throughput no yes
DDX3Y_HUMAN [view interactions] High throughput no yes
BCL7B_HUMAN [view interactions] High throughput no yes
OST48_HUMAN [view entry] [view interactions] High throughput yes yes
OST4_HUMAN [view interactions] High throughput no no
PIN4_HUMAN [view interactions] High throughput no yes
STT3B_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
RS20_HUMAN [view entry] [view interactions] High throughput yes yes
RS24_HUMAN [view entry] [view interactions] High throughput yes yes
SERB1_HUMAN [view interactions] High throughput no yes
CNOT3_HUMAN [view interactions] High throughput no yes
INLR1_HUMAN [view interactions] High throughput no no