RNF10_HUMAN
Evidence for PS localization
Functions
Transcriptional factor involved in the regulation of MAG (Myelin-associated glycoprotein) expression. Acts as a regulator of Schwann cell differentiation and myelination. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in RNF10_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 59.0909 | 4 | no |
| GO:0046872 | metal ion binding | 31.8182 | 4 | yes |
| GO:0042803 | protein homodimerization activity | 31.8182 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 22.7273 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 22.7273 | 4 | no |
| GO:0017076 | purine nucleotide binding | 22.7273 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 22.7273 | 6 | no |
| GO:0019900 | kinase binding | 22.7273 | 4 | no |
| GO:0019901 | protein kinase binding | 22.7273 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 22.7273 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.7273 | 4 | no |
| GO:0000976 | transcription cis-regulatory region binding | 13.6364 | 5 | yes |
| GO:0001067 | transcription regulatory region nucleic acid binding | 13.6364 | 4 | yes |
| GO:0003677 | DNA binding | 13.6364 | 4 | yes |
| GO:0003690 | double-stranded DNA binding | 13.6364 | 5 | yes |
| GO:0043565 | sequence-specific DNA binding | 13.6364 | 5 | yes |
| GO:1990837 | sequence-specific double-stranded DNA binding | 13.6364 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in RNF10_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 72.7273 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 68.1818 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 68.1818 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 68.1818 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 68.1818 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 59.0909 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 59.0909 | 4 | yes |
| GO:0010646 | regulation of cell communication | 59.0909 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 54.5455 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 50.0000 | 4 | yes |
| GO:0010468 | regulation of gene expression | 50.0000 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 50.0000 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 50.0000 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 50.0000 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 50.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 45.4545 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 45.4545 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 40.9091 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 40.9091 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 40.9091 | 5 | no |
| GO:0023056 | positive regulation of signaling | 40.9091 | 4 | no |
| GO:0071702 | organic substance transport | 40.9091 | 4 | no |
| GO:0071705 | nitrogen compound transport | 40.9091 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 40.9091 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 40.9091 | 5 | yes |
| GO:0051049 | regulation of transport | 36.3636 | 4 | no |
| GO:0080134 | regulation of response to stress | 36.3636 | 4 | no |
| GO:0008104 | protein localization | 36.3636 | 4 | no |
| GO:0009894 | regulation of catabolic process | 36.3636 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 36.3636 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 31.8182 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 31.8182 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 31.8182 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 31.8182 | 5 | no |
| GO:0015031 | protein transport | 31.8182 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 31.8182 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 31.8182 | 6 | no |
| GO:0031329 | regulation of cellular catabolic process | 31.8182 | 5 | no |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 31.8182 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 31.8182 | 5 | no |
| GO:0006996 | organelle organization | 31.8182 | 4 | no |
| GO:0090304 | nucleic acid metabolic process | 31.8182 | 4 | no |
| GO:0030162 | regulation of proteolysis | 31.8182 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 31.8182 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 31.8182 | 6 | yes |
| GO:0051252 | regulation of RNA metabolic process | 31.8182 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 31.8182 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.8182 | 5 | no |
| GO:0010941 | regulation of cell death | 31.8182 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 31.8182 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 27.2727 | 7 | no |
| GO:0051050 | positive regulation of transport | 27.2727 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 27.2727 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 27.2727 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 27.2727 | 4 | no |
| GO:0042176 | regulation of protein catabolic process | 27.2727 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 27.2727 | 7 | no |
| GO:0071310 | cellular response to organic substance | 27.2727 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 27.2727 | 5 | no |
| GO:0022607 | cellular component assembly | 27.2727 | 4 | no |
| GO:0043933 | protein-containing complex organization | 27.2727 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 27.2727 | 6 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 27.2727 | 6 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 27.2727 | 4 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 27.2727 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 27.2727 | 6 | yes |
| GO:0010648 | negative regulation of cell communication | 27.2727 | 5 | no |
| GO:0023057 | negative regulation of signaling | 27.2727 | 4 | no |
| GO:0043066 | negative regulation of apoptotic process | 22.7273 | 7 | no |
| GO:0043069 | negative regulation of programmed cell death | 22.7273 | 6 | no |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 22.7273 | 6 | no |
| GO:0051253 | negative regulation of RNA metabolic process | 22.7273 | 6 | no |
| GO:0060548 | negative regulation of cell death | 22.7273 | 5 | no |
| GO:0080135 | regulation of cellular response to stress | 22.7273 | 4 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 22.7273 | 5 | no |
| GO:0009059 | macromolecule biosynthetic process | 22.7273 | 4 | no |
| GO:0043549 | regulation of kinase activity | 22.7273 | 5 | no |
| GO:0051338 | regulation of transferase activity | 22.7273 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 22.7273 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 22.7273 | 7 | no |
| GO:0006886 | intracellular protein transport | 22.7273 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 22.7273 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 22.7273 | 6 | no |
| GO:0032880 | regulation of protein localization | 22.7273 | 5 | no |
| GO:0033365 | protein localization to organelle | 22.7273 | 5 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 22.7273 | 7 | no |
| GO:0060341 | regulation of cellular localization | 22.7273 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 22.7273 | 5 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 22.7273 | 6 | no |
| GO:0045862 | positive regulation of proteolysis | 22.7273 | 7 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.7273 | 6 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 22.7273 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 22.7273 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.7273 | 6 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 18.1818 | 7 | yes |
| GO:0036211 | protein modification process | 18.1818 | 4 | yes |
| GO:0043412 | macromolecule modification | 18.1818 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 18.1818 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 18.1818 | 4 | yes |
| GO:0044057 | regulation of system process | 13.6364 | 4 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 13.6364 | 6 | yes |
| GO:0051960 | regulation of nervous system development | 13.6364 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 13.6364 | 5 | yes |
| GO:0016567 | protein ubiquitination | 9.0909 | 7 | yes |
| GO:0031644 | regulation of nervous system process | 9.0909 | 5 | yes |
| GO:0032446 | protein modification by small protein conjugation | 9.0909 | 6 | yes |
| GO:0042127 | regulation of cell population proliferation | 9.0909 | 4 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 9.0909 | 7 | yes |
| GO:0050767 | regulation of neurogenesis | 9.0909 | 6 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 9.0909 | 4 | yes |
| GO:0060284 | regulation of cell development | 9.0909 | 5 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 9.0909 | 7 | yes |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 9.0909 | 8 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RASF1_HUMAN | [view interactions] | Low throughput | no | yes |
| MEOX2_HUMAN | [view interactions] | Low throughput | no | no |
| UBTD1_HUMAN | [view interactions] | Low throughput | no | no |
| HAUS3_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS4_HUMAN | [view interactions] | High throughput | no | yes |
| NCOA4_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAUS8_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS7_HUMAN | [view interactions] | High throughput | no | no |
| HAUS6_HUMAN | [view interactions] | High throughput | no | yes |
| CEP43_HUMAN | [view interactions] | High throughput | no | no |
| LRP5_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HAUS2_HUMAN | [view interactions] | High throughput | no | yes |
| DCAF5_HUMAN | [view interactions] | High throughput | no | yes |
| CATL2_HUMAN | [view interactions] | High throughput | no | yes |
| CE350_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS5_HUMAN | [view interactions] | High throughput | no | yes |
| P2R3B_HUMAN | [view interactions] | High throughput | no | no |
| ARI1B_HUMAN | [view interactions] | High throughput | no | yes |
| DDX23_HUMAN | [view interactions] | High throughput | no | yes |
| DDX3Y_HUMAN | [view interactions] | High throughput | no | yes |
| BCL7B_HUMAN | [view interactions] | High throughput | no | yes |
| OST48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OST4_HUMAN | [view interactions] | High throughput | no | no |
| PIN4_HUMAN | [view interactions] | High throughput | no | yes |
| STT3B_HUMAN | [view interactions] | High throughput | no | yes |
| RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAIRB_HUMAN | [view interactions] | High throughput | no | yes |
| MYLK_HUMAN | [view interactions] | High throughput | no | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2D1_HUMAN | [view interactions] | High throughput | no | yes |
| UB2D2_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| MIS12_HUMAN | [view interactions] | High throughput | no | yes |
| CD2AP_HUMAN | [view interactions] | High throughput | no | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2D3_HUMAN | [view interactions] | High throughput | no | yes |
| UB2E1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC9_HUMAN | [view interactions] | High throughput | no | yes |
| UB2E3_HUMAN | [view interactions] | High throughput | no | yes |
| UB2D4_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| UB2E2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| UB2V1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBE2W_HUMAN | [view interactions] | High throughput | no | yes |
| UB2Q2_HUMAN | [view interactions] | High throughput | no | no |
| UBE2U_HUMAN | [view interactions] | High throughput | no | no |
| MDM2_HUMAN | [view interactions] | High throughput | no | yes |
| TRI26_HUMAN | [view interactions] | High throughput | no | yes |
| CASP6_HUMAN | [view interactions] | High throughput | no | no |
| HIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF11_HUMAN | [view interactions] | High throughput | no | yes |
| COQ8A_HUMAN | [view interactions] | High throughput | no | no |
| SPRE1_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SETB1_HUMAN | [view interactions] | High throughput | no | yes |
| TLE1_HUMAN | [view interactions] | High throughput | no | yes |
| CC90B_HUMAN | [view interactions] | High throughput | no | yes |
| RIF1_HUMAN | [view interactions] | High throughput | no | yes |
| UT14A_HUMAN | [view interactions] | High throughput | no | yes |
| CO4A5_HUMAN | [view interactions] | High throughput | no | no |
| DYSF_HUMAN | [view interactions] | High throughput | no | no |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI55_HUMAN | [view interactions] | High throughput | no | no |
| LRIF1_HUMAN | [view interactions] | High throughput | no | yes |
| UB2J2_HUMAN | [view interactions] | High throughput | no | no |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| TBCC1_HUMAN | [view interactions] | High throughput | no | no |