GSLG1_HUMAN
Evidence for PS localization
Functions
Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GSLG1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 26.9231 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 26.9231 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 23.0769 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 23.0769 | 5 | no |
| GO:0003723 | RNA binding | 23.0769 | 4 | no |
| GO:0016301 | kinase activity | 23.0769 | 4 | no |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 23.0769 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.0769 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GSLG1_HUMAN |
|---|---|---|---|---|
| GO:0051171 | regulation of nitrogen compound metabolic process | 65.3846 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 65.3846 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 65.3846 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 53.8462 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 53.8462 | 4 | no |
| GO:0010646 | regulation of cell communication | 53.8462 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 50.0000 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 42.3077 | 4 | no |
| GO:0009966 | regulation of signal transduction | 42.3077 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 42.3077 | 4 | yes |
| GO:0036211 | protein modification process | 38.4615 | 4 | no |
| GO:0043412 | macromolecule modification | 38.4615 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 38.4615 | 5 | no |
| GO:0023056 | positive regulation of signaling | 38.4615 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 38.4615 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 38.4615 | 4 | no |
| GO:0010468 | regulation of gene expression | 38.4615 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 34.6154 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 34.6154 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.6154 | 5 | no |
| GO:0010941 | regulation of cell death | 34.6154 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 34.6154 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 34.6154 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 34.6154 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 34.6154 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 34.6154 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 34.6154 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 34.6154 | 5 | yes |
| GO:2000026 | regulation of multicellular organismal development | 30.7692 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 30.7692 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 30.7692 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 30.7692 | 6 | no |
| GO:0009889 | regulation of biosynthetic process | 30.7692 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 30.7692 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.7692 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 30.7692 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 30.7692 | 6 | no |
| GO:0008284 | positive regulation of cell population proliferation | 30.7692 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 30.7692 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 30.7692 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 30.7692 | 6 | no |
| GO:0051049 | regulation of transport | 30.7692 | 4 | no |
| GO:0031399 | regulation of protein modification process | 30.7692 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 30.7692 | 5 | yes |
| GO:0010648 | negative regulation of cell communication | 30.7692 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 30.7692 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 30.7692 | 4 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 26.9231 | 5 | yes |
| GO:0006508 | proteolysis | 26.9231 | 4 | no |
| GO:0009894 | regulation of catabolic process | 26.9231 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 26.9231 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 26.9231 | 6 | no |
| GO:0060548 | negative regulation of cell death | 26.9231 | 5 | no |
| GO:0008104 | protein localization | 26.9231 | 4 | no |
| GO:0009057 | macromolecule catabolic process | 23.0769 | 4 | no |
| GO:0006996 | organelle organization | 23.0769 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 23.0769 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.0769 | 6 | no |
| GO:0033043 | regulation of organelle organization | 23.0769 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 23.0769 | 7 | no |
| GO:0042327 | positive regulation of phosphorylation | 23.0769 | 8 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 23.0769 | 7 | no |
| GO:0051050 | positive regulation of transport | 23.0769 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 23.0769 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.0769 | 5 | no |
| GO:0060341 | regulation of cellular localization | 23.0769 | 4 | no |
| GO:0071310 | cellular response to organic substance | 23.0769 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.0769 | 5 | no |
| GO:0043066 | negative regulation of apoptotic process | 23.0769 | 7 | no |
| GO:0043069 | negative regulation of programmed cell death | 23.0769 | 6 | no |
| GO:0032101 | regulation of response to external stimulus | 23.0769 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 23.0769 | 7 | no |
| GO:0045595 | regulation of cell differentiation | 23.0769 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 19.2308 | 6 | yes |
| GO:0010629 | negative regulation of gene expression | 15.3846 | 6 | yes |
| GO:0030162 | regulation of proteolysis | 15.3846 | 6 | yes |
| GO:0090287 | regulation of cellular response to growth factor stimulus | 11.5385 | 4 | yes |
| GO:0090092 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | 7.6923 | 5 | yes |
| GO:0090101 | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | 7.6923 | 6 | yes |
| GO:1903317 | regulation of protein maturation | 7.6923 | 6 | yes |
| GO:1903844 | regulation of cellular response to transforming growth factor beta stimulus | 7.6923 | 5 | yes |
| GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway | 7.6923 | 6 | yes |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 7.6923 | 7 | yes |
| GO:0045861 | negative regulation of proteolysis | 7.6923 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in GSLG1_HUMAN |
|---|---|---|---|---|
| DOID:37 | skin disease | 7.6923 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LYAM2_HUMAN | [view interactions] | Low throughput | no | no |
| FGF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| MLKL_HUMAN | [view interactions] | High throughput | no | no |
| RFWD3_HUMAN | [view interactions] | High throughput | no | yes |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| MK07_HUMAN | [view interactions] | High throughput | no | yes |
| PDPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK16_HUMAN | [view interactions] | High throughput | no | no |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KSYK_HUMAN | [view interactions] | High throughput | no | no |
| AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
| CAMKV_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEK7_HUMAN | [view interactions] | High throughput | no | yes |
| M4K1_HUMAN | [view interactions] | High throughput | no | no |
| PMYT1_HUMAN | [view interactions] | High throughput | no | no |
| SIK3_HUMAN | [view interactions] | High throughput | no | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| NFKB2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| GRK5_HUMAN | [view interactions] | High throughput | no | yes |
| PAN2_HUMAN | [view interactions] | High throughput | no | no |
| STB5L_HUMAN | [view interactions] | High throughput | no | no |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| KLK2_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| GINM1_HUMAN | [view interactions] | High throughput | no | yes |
| CGRF1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRK_HUMAN | [view interactions] | High throughput | no | no |
| PG12B_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| IFIX_HUMAN | [view interactions] | High throughput | no | no |
| SPP2B_HUMAN | [view interactions] | High throughput | no | yes |
| UST_HUMAN | [view interactions] | High throughput | no | yes |
| DKK3_HUMAN | [view interactions] | High throughput | no | yes |
| SG2A2_HUMAN | [view interactions] | High throughput | no | no |
| FA8A1_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| REL_HUMAN | [view interactions] | High throughput | no | yes |
| TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| DJC25_HUMAN | [view interactions] | High throughput | no | yes |
| AMFR_HUMAN | [view interactions] | High throughput | no | yes |
| RN128_HUMAN | [view interactions] | High throughput | no | yes |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSBL8_HUMAN | [view interactions] | High throughput | no | yes |
| TFR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PATE1_HUMAN | [view interactions] | High throughput | no | no |
| FBX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GTR8_HUMAN | [view interactions] | High throughput | no | yes |
| FOLH1_HUMAN | [view interactions] | High throughput | no | no |
| HEPS_HUMAN | [view interactions] | High throughput | no | yes |
| NRSN1_HUMAN | [view interactions] | High throughput | no | yes |
| ST14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EI2BE_HUMAN | [view interactions] | High throughput | no | yes |
| FSD2_HUMAN | [view interactions] | High throughput | no | no |
| APOC3_HUMAN | [view interactions] | High throughput | no | no |
| MSH5_HUMAN | [view interactions] | High throughput | no | no |
| AQP3_HUMAN | [view interactions] | High throughput | no | no |
| SDF2L_HUMAN | [view interactions] | High throughput | no | yes |
| PRG2_HUMAN | [view interactions] | High throughput | no | no |
| STX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LEG1_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4R_HUMAN | [view interactions] | High throughput | no | no |
| ETFR1_HUMAN | [view interactions] | High throughput | no | no |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| TM192_HUMAN | [view interactions] | High throughput | no | yes |
| OXLA_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENDD1_HUMAN | [view interactions] | High throughput | no | yes |
| EPDR1_HUMAN | [view interactions] | High throughput | no | yes |
| DIP2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM8B_HUMAN | [view interactions] | High throughput | no | yes |
| VTI1A_HUMAN | [view interactions] | High throughput | no | yes |
| UGGG1_HUMAN | [view interactions] | High throughput | no | yes |
| ABHDA_HUMAN | [view interactions] | High throughput | no | yes |
| NMS_HUMAN | [view interactions] | High throughput | no | no |
| NGLY1_HUMAN | [view interactions] | High throughput | no | yes |
| SYPM_HUMAN | [view interactions] | High throughput | no | yes |
| TM38B_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| T106B_HUMAN | [view interactions] | High throughput | no | yes |
| TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
| LYAM3_HUMAN | [view interactions] | Computational | no | no |