FGF2_HUMAN
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed). Also acts as an integrin ligand which is required for FGF2 signaling (PubMed). Binds to integrin ITGAV:ITGB3 (PubMed). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (PubMed, PubMed). Functions as a potent mitogen in vitro (PubMed, PubMed, PubMed). Can induce angiogenesis (PubMed, PubMed). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in FGF2_HUMAN |
---|---|---|---|---|
GO:0043169 | cation binding | 36.0000 | 4 | no |
GO:0046872 | metal ion binding | 36.0000 | 5 | no |
GO:0000166 | nucleotide binding | 32.0000 | 4 | no |
GO:0016301 | kinase activity | 32.0000 | 4 | no |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 32.0000 | 4 | no |
GO:0017076 | purine nucleotide binding | 32.0000 | 5 | no |
GO:0043168 | anion binding | 32.0000 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 28.0000 | 6 | no |
GO:0032555 | purine ribonucleotide binding | 28.0000 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 28.0000 | 4 | no |
GO:0004674 | protein serine/threonine kinase activity | 24.0000 | 4 | no |
GO:0005524 | ATP binding | 24.0000 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 24.0000 | 5 | no |
GO:0019900 | kinase binding | 24.0000 | 4 | no |
GO:0019901 | protein kinase binding | 24.0000 | 5 | no |
GO:0090722 | receptor-receptor interaction | 12.0000 | 4 | yes |
GO:0005104 | fibroblast growth factor receptor binding | 8.0000 | 5 | yes |
GO:0005125 | cytokine activity | 8.0000 | 5 | yes |
GO:0008083 | growth factor activity | 8.0000 | 5 | yes |
GO:0019956 | chemokine binding | 8.0000 | 4 | yes |
GO:0030374 | nuclear receptor coactivator activity | 8.0000 | 4 | yes |
GO:0042056 | chemoattractant activity | 8.0000 | 5 | yes |
GO:0048018 | receptor ligand activity | 8.0000 | 4 | yes |
GO:0070851 | growth factor receptor binding | 8.0000 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in FGF2_HUMAN |
---|---|---|---|---|
GO:0009966 | regulation of signal transduction | 72.0000 | 4 | yes |
GO:0010646 | regulation of cell communication | 72.0000 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 68.0000 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 64.0000 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 64.0000 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 64.0000 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 64.0000 | 4 | yes |
GO:1902531 | regulation of intracellular signal transduction | 56.0000 | 5 | yes |
GO:0009892 | negative regulation of metabolic process | 56.0000 | 4 | yes |
GO:0010647 | positive regulation of cell communication | 56.0000 | 5 | yes |
GO:0023056 | positive regulation of signaling | 56.0000 | 4 | yes |
GO:0048584 | positive regulation of response to stimulus | 56.0000 | 4 | yes |
GO:0048585 | negative regulation of response to stimulus | 56.0000 | 4 | yes |
GO:0009967 | positive regulation of signal transduction | 52.0000 | 5 | yes |
GO:0051246 | regulation of protein metabolic process | 52.0000 | 5 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 48.0000 | 6 | yes |
GO:0009889 | regulation of biosynthetic process | 48.0000 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 48.0000 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 48.0000 | 5 | yes |
GO:0010468 | regulation of gene expression | 48.0000 | 6 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 48.0000 | 5 | yes |
GO:0051128 | regulation of cellular component organization | 48.0000 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 48.0000 | 5 | yes |
GO:0010648 | negative regulation of cell communication | 48.0000 | 5 | yes |
GO:0023057 | negative regulation of signaling | 48.0000 | 4 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 48.0000 | 5 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 44.0000 | 5 | yes |
GO:0043067 | regulation of programmed cell death | 44.0000 | 4 | yes |
GO:0045595 | regulation of cell differentiation | 44.0000 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 40.0000 | 5 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 40.0000 | 5 | yes |
GO:0019220 | regulation of phosphate metabolic process | 40.0000 | 6 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 40.0000 | 5 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 40.0000 | 5 | yes |
GO:0080134 | regulation of response to stress | 36.0000 | 4 | yes |
GO:0009890 | negative regulation of biosynthetic process | 36.0000 | 5 | yes |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 36.0000 | 6 | yes |
GO:0042981 | regulation of apoptotic process | 36.0000 | 5 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 36.0000 | 4 | yes |
GO:0031327 | negative regulation of cellular biosynthetic process | 36.0000 | 6 | yes |
GO:0032101 | regulation of response to external stimulus | 36.0000 | 4 | yes |
GO:0042127 | regulation of cell population proliferation | 36.0000 | 4 | yes |
GO:0051094 | positive regulation of developmental process | 36.0000 | 4 | yes |
GO:0051241 | negative regulation of multicellular organismal process | 36.0000 | 4 | yes |
GO:0051247 | positive regulation of protein metabolic process | 36.0000 | 6 | yes |
GO:0051252 | regulation of RNA metabolic process | 36.0000 | 5 | yes |
GO:0090304 | nucleic acid metabolic process | 32.0000 | 4 | yes |
GO:0001932 | regulation of protein phosphorylation | 32.0000 | 7 | yes |
GO:0006355 | regulation of DNA-templated transcription | 32.0000 | 7 | yes |
GO:2000026 | regulation of multicellular organismal development | 32.0000 | 4 | yes |
GO:0008284 | positive regulation of cell population proliferation | 32.0000 | 5 | yes |
GO:2001141 | regulation of RNA biosynthetic process | 32.0000 | 6 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 32.0000 | 4 | no |
GO:0036211 | protein modification process | 32.0000 | 4 | no |
GO:0043412 | macromolecule modification | 32.0000 | 4 | no |
GO:0010629 | negative regulation of gene expression | 32.0000 | 7 | yes |
GO:0022607 | cellular component assembly | 32.0000 | 4 | no |
GO:0031399 | regulation of protein modification process | 32.0000 | 6 | yes |
GO:0031401 | positive regulation of protein modification process | 32.0000 | 7 | yes |
GO:0042325 | regulation of phosphorylation | 32.0000 | 7 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 32.0000 | 4 | yes |
GO:0051726 | regulation of cell cycle | 28.0000 | 4 | yes |
GO:0001934 | positive regulation of protein phosphorylation | 28.0000 | 8 | yes |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 28.0000 | 4 | yes |
GO:2000145 | regulation of cell motility | 28.0000 | 4 | yes |
GO:0009059 | macromolecule biosynthetic process | 28.0000 | 4 | yes |
GO:0016310 | phosphorylation | 28.0000 | 5 | no |
GO:0030162 | regulation of proteolysis | 28.0000 | 6 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 28.0000 | 6 | yes |
GO:0043066 | negative regulation of apoptotic process | 28.0000 | 6 | no |
GO:0043069 | negative regulation of programmed cell death | 28.0000 | 5 | no |
GO:0051248 | negative regulation of protein metabolic process | 28.0000 | 6 | no |
GO:2001233 | regulation of apoptotic signaling pathway | 28.0000 | 5 | no |
GO:0060341 | regulation of cellular localization | 28.0000 | 4 | no |
GO:0030334 | regulation of cell migration | 28.0000 | 5 | yes |
GO:0042327 | positive regulation of phosphorylation | 28.0000 | 8 | yes |
GO:0043408 | regulation of MAPK cascade | 28.0000 | 6 | yes |
GO:0045597 | positive regulation of cell differentiation | 28.0000 | 5 | yes |
GO:0045937 | positive regulation of phosphate metabolic process | 28.0000 | 7 | yes |
GO:0060284 | regulation of cell development | 24.0000 | 5 | yes |
GO:0090287 | regulation of cellular response to growth factor stimulus | 24.0000 | 4 | yes |
GO:0141124 | intracellular signaling cassette | 24.0000 | 4 | yes |
GO:2000147 | positive regulation of cell motility | 24.0000 | 5 | yes |
GO:0009891 | positive regulation of biosynthetic process | 24.0000 | 5 | yes |
GO:0006468 | protein phosphorylation | 24.0000 | 5 | no |
GO:0018193 | peptidyl-amino acid modification | 24.0000 | 5 | no |
GO:0010594 | regulation of endothelial cell migration | 24.0000 | 5 | yes |
GO:0051336 | regulation of hydrolase activity | 24.0000 | 4 | no |
GO:0032880 | regulation of protein localization | 24.0000 | 5 | no |
GO:0010632 | regulation of epithelial cell migration | 24.0000 | 4 | yes |
GO:0010243 | response to organonitrogen compound | 24.0000 | 4 | no |
GO:0071310 | cellular response to organic substance | 24.0000 | 4 | no |
GO:0071417 | cellular response to organonitrogen compound | 24.0000 | 4 | no |
GO:1901699 | cellular response to nitrogen compound | 24.0000 | 4 | no |
GO:1901701 | cellular response to oxygen-containing compound | 24.0000 | 4 | no |
GO:0030030 | cell projection organization | 24.0000 | 4 | no |
GO:0051049 | regulation of transport | 24.0000 | 4 | no |
GO:0006996 | organelle organization | 24.0000 | 4 | no |
GO:0043933 | protein-containing complex organization | 24.0000 | 4 | no |
GO:0065003 | protein-containing complex assembly | 24.0000 | 5 | no |
GO:0016055 | Wnt signaling pathway | 24.0000 | 4 | yes |
GO:0016070 | RNA metabolic process | 24.0000 | 5 | yes |
GO:0030335 | positive regulation of cell migration | 24.0000 | 6 | yes |
GO:0031328 | positive regulation of cellular biosynthetic process | 24.0000 | 6 | yes |
GO:0032102 | negative regulation of response to external stimulus | 24.0000 | 5 | yes |
GO:0032103 | positive regulation of response to external stimulus | 24.0000 | 5 | yes |
GO:0040017 | positive regulation of locomotion | 24.0000 | 4 | yes |
GO:0043085 | positive regulation of catalytic activity | 24.0000 | 4 | yes |
GO:0043410 | positive regulation of MAPK cascade | 24.0000 | 7 | yes |
GO:0043535 | regulation of blood vessel endothelial cell migration | 24.0000 | 6 | yes |
GO:0045927 | positive regulation of growth | 24.0000 | 4 | yes |
GO:0048638 | regulation of developmental growth | 24.0000 | 4 | yes |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 20.0000 | 7 | yes |
GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 20.0000 | 8 | yes |
GO:1901565 | organonitrogen compound catabolic process | 20.0000 | 4 | yes |
GO:0001936 | regulation of endothelial cell proliferation | 20.0000 | 6 | yes |
GO:0001938 | positive regulation of endothelial cell proliferation | 20.0000 | 7 | yes |
GO:0002009 | morphogenesis of an epithelium | 20.0000 | 4 | yes |
GO:0006357 | regulation of transcription by RNA polymerase II | 20.0000 | 8 | yes |
GO:0007169 | cell surface receptor protein tyrosine kinase signaling pathway | 20.0000 | 5 | yes |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.0000 | 6 | yes |
GO:0010595 | positive regulation of endothelial cell migration | 20.0000 | 6 | yes |
GO:0010634 | positive regulation of epithelial cell migration | 20.0000 | 5 | yes |
GO:0043536 | positive regulation of blood vessel endothelial cell migration | 20.0000 | 7 | yes |
GO:0043549 | regulation of kinase activity | 20.0000 | 5 | yes |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 20.0000 | 5 | yes |
GO:0048639 | positive regulation of developmental growth | 20.0000 | 5 | yes |
GO:0050678 | regulation of epithelial cell proliferation | 20.0000 | 5 | yes |
GO:0050679 | positive regulation of epithelial cell proliferation | 20.0000 | 6 | yes |
GO:0050920 | regulation of chemotaxis | 20.0000 | 4 | yes |
GO:0050921 | positive regulation of chemotaxis | 20.0000 | 5 | yes |
GO:0051338 | regulation of transferase activity | 20.0000 | 4 | yes |
GO:0051347 | positive regulation of transferase activity | 16.0000 | 5 | yes |
GO:0051896 | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 16.0000 | 6 | yes |
GO:0051897 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 16.0000 | 7 | yes |
GO:0051960 | regulation of nervous system development | 16.0000 | 5 | yes |
GO:1901342 | regulation of vasculature development | 16.0000 | 5 | yes |
GO:1902680 | positive regulation of RNA biosynthetic process | 16.0000 | 7 | yes |
GO:0000165 | MAPK cascade | 16.0000 | 5 | yes |
GO:1904018 | positive regulation of vasculature development | 16.0000 | 5 | yes |
GO:1905562 | regulation of vascular endothelial cell proliferation | 16.0000 | 7 | yes |
GO:1905564 | positive regulation of vascular endothelial cell proliferation | 16.0000 | 8 | yes |
GO:0009057 | macromolecule catabolic process | 16.0000 | 4 | yes |
GO:0010628 | positive regulation of gene expression | 16.0000 | 7 | yes |
GO:0010720 | positive regulation of cell development | 16.0000 | 6 | yes |
GO:0030111 | regulation of Wnt signaling pathway | 16.0000 | 5 | yes |
GO:0033674 | positive regulation of kinase activity | 16.0000 | 6 | yes |
GO:0040013 | negative regulation of locomotion | 16.0000 | 4 | yes |
GO:0045664 | regulation of neuron differentiation | 16.0000 | 5 | yes |
GO:0045666 | positive regulation of neuron differentiation | 16.0000 | 6 | yes |
GO:0045765 | regulation of angiogenesis | 16.0000 | 5 | yes |
GO:0045766 | positive regulation of angiogenesis | 16.0000 | 6 | yes |
GO:0045859 | regulation of protein kinase activity | 16.0000 | 6 | yes |
GO:0045860 | positive regulation of protein kinase activity | 16.0000 | 7 | yes |
GO:0045893 | positive regulation of DNA-templated transcription | 16.0000 | 8 | yes |
GO:0045944 | positive regulation of transcription by RNA polymerase II | 16.0000 | 9 | yes |
GO:0050767 | regulation of neurogenesis | 16.0000 | 6 | yes |
GO:0051052 | regulation of DNA metabolic process | 16.0000 | 5 | yes |
GO:0051054 | positive regulation of DNA metabolic process | 16.0000 | 6 | yes |
GO:0051254 | positive regulation of RNA metabolic process | 16.0000 | 6 | yes |
GO:0051282 | regulation of sequestering of calcium ion | 16.0000 | 4 | yes |
GO:0051781 | positive regulation of cell division | 12.0000 | 5 | yes |
GO:0051962 | positive regulation of nervous system development | 12.0000 | 5 | yes |
GO:0055021 | regulation of cardiac muscle tissue growth | 12.0000 | 6 | yes |
GO:0055023 | positive regulation of cardiac muscle tissue growth | 12.0000 | 7 | yes |
GO:0060043 | regulation of cardiac muscle cell proliferation | 12.0000 | 5 | yes |
GO:0060045 | positive regulation of cardiac muscle cell proliferation | 12.0000 | 6 | yes |
GO:0060420 | regulation of heart growth | 12.0000 | 5 | yes |
GO:0060421 | positive regulation of heart growth | 12.0000 | 6 | yes |
GO:0060828 | regulation of canonical Wnt signaling pathway | 12.0000 | 6 | yes |
GO:0060978 | angiogenesis involved in coronary vascular morphogenesis | 12.0000 | 4 | yes |
GO:0071900 | regulation of protein serine/threonine kinase activity | 12.0000 | 7 | yes |
GO:0071902 | positive regulation of protein serine/threonine kinase activity | 12.0000 | 8 | yes |
GO:0072091 | regulation of stem cell proliferation | 12.0000 | 5 | yes |
GO:0090049 | regulation of cell migration involved in sprouting angiogenesis | 12.0000 | 7 | yes |
GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis | 12.0000 | 8 | yes |
GO:0110110 | positive regulation of animal organ morphogenesis | 12.0000 | 5 | yes |
GO:0141187 | nucleic acid biosynthetic process | 12.0000 | 5 | yes |
GO:1901136 | carbohydrate derivative catabolic process | 12.0000 | 4 | yes |
GO:1901362 | organic cyclic compound biosynthetic process | 12.0000 | 4 | yes |
GO:0001667 | ameboidal-type cell migration | 12.0000 | 4 | yes |
GO:1903034 | regulation of response to wounding | 12.0000 | 5 | yes |
GO:1903035 | negative regulation of response to wounding | 12.0000 | 5 | yes |
GO:1903510 | mucopolysaccharide metabolic process | 12.0000 | 6 | yes |
GO:0002042 | cell migration involved in sprouting angiogenesis | 12.0000 | 8 | yes |
GO:1903670 | regulation of sprouting angiogenesis | 12.0000 | 6 | yes |
GO:1903672 | positive regulation of sprouting angiogenesis | 12.0000 | 7 | yes |
GO:0003156 | regulation of animal organ formation | 12.0000 | 6 | yes |
GO:0006022 | aminoglycan metabolic process | 12.0000 | 4 | yes |
GO:1904847 | regulation of cell chemotaxis to fibroblast growth factor | 12.0000 | 5 | yes |
GO:0006026 | aminoglycan catabolic process | 12.0000 | 5 | yes |
GO:1904849 | positive regulation of cell chemotaxis to fibroblast growth factor | 12.0000 | 6 | yes |
GO:0006027 | glycosaminoglycan catabolic process | 12.0000 | 6 | yes |
GO:0006351 | DNA-templated transcription | 12.0000 | 6 | yes |
GO:1905330 | regulation of morphogenesis of an epithelium | 12.0000 | 5 | yes |
GO:0006366 | transcription by RNA polymerase II | 12.0000 | 7 | yes |
GO:2000027 | regulation of animal organ morphogenesis | 12.0000 | 5 | yes |
GO:2000146 | negative regulation of cell motility | 12.0000 | 5 | yes |
GO:0008285 | negative regulation of cell population proliferation | 12.0000 | 5 | yes |
GO:2000544 | regulation of endothelial cell chemotaxis to fibroblast growth factor | 12.0000 | 6 | yes |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 12.0000 | 6 | yes |
GO:2000546 | positive regulation of endothelial cell chemotaxis to fibroblast growth factor | 12.0000 | 7 | yes |
GO:0009792 | embryo development ending in birth or egg hatching | 12.0000 | 4 | yes |
GO:2000648 | positive regulation of stem cell proliferation | 12.0000 | 6 | yes |
GO:2001026 | regulation of endothelial cell chemotaxis | 12.0000 | 5 | yes |
GO:2001028 | positive regulation of endothelial cell chemotaxis | 12.0000 | 6 | yes |
GO:0010453 | regulation of cell fate commitment | 12.0000 | 4 | yes |
GO:0010596 | negative regulation of endothelial cell migration | 12.0000 | 6 | yes |
GO:0010631 | epithelial cell migration | 12.0000 | 5 | yes |
GO:0010633 | negative regulation of epithelial cell migration | 12.0000 | 5 | yes |
GO:0030177 | positive regulation of Wnt signaling pathway | 12.0000 | 6 | yes |
GO:0030203 | glycosaminoglycan metabolic process | 12.0000 | 5 | yes |
GO:0030212 | hyaluronan metabolic process | 12.0000 | 7 | yes |
GO:0030214 | hyaluronan catabolic process | 12.0000 | 7 | yes |
GO:0030336 | negative regulation of cell migration | 12.0000 | 6 | yes |
GO:0032774 | RNA biosynthetic process | 12.0000 | 5 | yes |
GO:0034654 | nucleobase-containing compound biosynthetic process | 12.0000 | 4 | yes |
GO:0042659 | regulation of cell fate specification | 12.0000 | 5 | yes |
GO:0043405 | regulation of MAP kinase activity | 12.0000 | 8 | yes |
GO:0043406 | positive regulation of MAP kinase activity | 12.0000 | 8 | yes |
GO:0043534 | blood vessel endothelial cell migration | 12.0000 | 7 | yes |
GO:0043537 | negative regulation of blood vessel endothelial cell migration | 12.0000 | 7 | yes |
GO:0043542 | endothelial cell migration | 12.0000 | 6 | yes |
GO:0045667 | regulation of osteoblast differentiation | 12.0000 | 5 | yes |
GO:0046620 | regulation of organ growth | 12.0000 | 4 | yes |
GO:0046622 | positive regulation of organ growth | 12.0000 | 5 | yes |
GO:0048754 | branching morphogenesis of an epithelial tube | 12.0000 | 4 | yes |
GO:0050769 | positive regulation of neurogenesis | 12.0000 | 6 | yes |
GO:0051302 | regulation of cell division | 12.0000 | 4 | yes |
GO:0060070 | canonical Wnt signaling pathway | 8.0000 | 5 | yes |
GO:0060113 | inner ear receptor cell differentiation | 8.0000 | 6 | yes |
GO:0060128 | corticotropin hormone secreting cell differentiation | 8.0000 | 4 | yes |
GO:0060129 | thyroid-stimulating hormone-secreting cell differentiation | 8.0000 | 6 | yes |
GO:0060563 | neuroepithelial cell differentiation | 8.0000 | 6 | yes |
GO:0060591 | chondroblast differentiation | 8.0000 | 4 | yes |
GO:0060644 | mammary gland epithelial cell differentiation | 8.0000 | 5 | yes |
GO:0061041 | regulation of wound healing | 8.0000 | 6 | yes |
GO:0061045 | negative regulation of wound healing | 8.0000 | 6 | yes |
GO:0061101 | neuroendocrine cell differentiation | 8.0000 | 5 | yes |
GO:0070371 | ERK1 and ERK2 cascade | 8.0000 | 6 | yes |
GO:0070588 | calcium ion transmembrane transport | 8.0000 | 5 | yes |
GO:0071260 | cellular response to mechanical stimulus | 8.0000 | 4 | yes |
GO:0090263 | positive regulation of canonical Wnt signaling pathway | 8.0000 | 7 | yes |
GO:0090288 | negative regulation of cellular response to growth factor stimulus | 8.0000 | 5 | yes |
GO:0097553 | calcium ion transmembrane import into cytosol | 8.0000 | 6 | yes |
GO:0098655 | monoatomic cation transmembrane transport | 8.0000 | 4 | yes |
GO:0098662 | inorganic cation transmembrane transport | 8.0000 | 4 | yes |
GO:1902692 | regulation of neuroblast proliferation | 8.0000 | 6 | yes |
GO:0001649 | osteoblast differentiation | 8.0000 | 4 | yes |
GO:1902746 | regulation of lens fiber cell differentiation | 8.0000 | 6 | yes |
GO:0001658 | branching involved in ureteric bud morphogenesis | 8.0000 | 5 | yes |
GO:1902748 | positive regulation of lens fiber cell differentiation | 8.0000 | 5 | yes |
GO:1902893 | regulation of miRNA transcription | 8.0000 | 7 | yes |
GO:1902895 | positive regulation of miRNA transcription | 8.0000 | 8 | yes |
GO:1902913 | positive regulation of neuroepithelial cell differentiation | 8.0000 | 7 | yes |
GO:0001935 | endothelial cell proliferation | 8.0000 | 4 | yes |
GO:1903587 | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | 8.0000 | 7 | yes |
GO:0002052 | positive regulation of neuroblast proliferation | 8.0000 | 7 | yes |
GO:0002065 | columnar/cuboidal epithelial cell differentiation | 8.0000 | 5 | yes |
GO:0002067 | glandular epithelial cell differentiation | 8.0000 | 6 | yes |
GO:1904705 | regulation of vascular associated smooth muscle cell proliferation | 8.0000 | 6 | yes |
GO:1904707 | positive regulation of vascular associated smooth muscle cell proliferation | 8.0000 | 7 | yes |
GO:1904977 | lymphatic endothelial cell migration | 8.0000 | 7 | yes |
GO:1905276 | regulation of epithelial tube formation | 8.0000 | 5 | yes |
GO:1905278 | positive regulation of epithelial tube formation | 8.0000 | 5 | yes |
GO:1905332 | positive regulation of morphogenesis of an epithelium | 8.0000 | 5 | yes |
GO:0006811 | monoatomic ion transport | 8.0000 | 4 | yes |
GO:0006812 | monoatomic cation transport | 8.0000 | 5 | yes |
GO:0006816 | calcium ion transport | 8.0000 | 7 | yes |
GO:0007264 | small GTPase-mediated signal transduction | 8.0000 | 5 | yes |
GO:0007265 | Ras protein signal transduction | 8.0000 | 6 | yes |
GO:0007399 | nervous system development | 8.0000 | 4 | yes |
GO:2000177 | regulation of neural precursor cell proliferation | 8.0000 | 5 | yes |
GO:0007405 | neuroblast proliferation | 8.0000 | 4 | yes |
GO:2000179 | positive regulation of neural precursor cell proliferation | 8.0000 | 6 | yes |
GO:2000278 | regulation of DNA biosynthetic process | 8.0000 | 6 | yes |
GO:2000573 | positive regulation of DNA biosynthetic process | 8.0000 | 7 | yes |
GO:2000628 | regulation of miRNA metabolic process | 8.0000 | 6 | yes |
GO:2000630 | positive regulation of miRNA metabolic process | 8.0000 | 7 | yes |
GO:2000647 | negative regulation of stem cell proliferation | 8.0000 | 6 | yes |
GO:2000736 | regulation of stem cell differentiation | 8.0000 | 5 | yes |
GO:2000738 | positive regulation of stem cell differentiation | 8.0000 | 6 | yes |
GO:2000980 | regulation of inner ear receptor cell differentiation | 8.0000 | 7 | yes |
GO:0009913 | epidermal cell differentiation | 8.0000 | 5 | yes |
GO:2000982 | positive regulation of inner ear receptor cell differentiation | 8.0000 | 8 | yes |
GO:0010001 | glial cell differentiation | 8.0000 | 4 | yes |
GO:0010455 | positive regulation of cell fate commitment | 8.0000 | 5 | yes |
GO:0010762 | regulation of fibroblast migration | 8.0000 | 6 | yes |
GO:0010764 | negative regulation of fibroblast migration | 8.0000 | 7 | yes |
GO:0014842 | regulation of skeletal muscle satellite cell proliferation | 8.0000 | 6 | yes |
GO:0014843 | growth factor dependent regulation of skeletal muscle satellite cell proliferation | 8.0000 | 7 | yes |
GO:0014857 | regulation of skeletal muscle cell proliferation | 8.0000 | 5 | yes |
GO:0021534 | cell proliferation in hindbrain | 8.0000 | 4 | yes |
GO:0021762 | substantia nigra development | 8.0000 | 4 | yes |
GO:0021924 | cell proliferation in external granule layer | 8.0000 | 5 | yes |
GO:0021930 | cerebellar granule cell precursor proliferation | 8.0000 | 6 | yes |
GO:0021936 | regulation of cerebellar granule cell precursor proliferation | 8.0000 | 6 | yes |
GO:0021940 | positive regulation of cerebellar granule cell precursor proliferation | 8.0000 | 7 | yes |
GO:0030001 | metal ion transport | 8.0000 | 6 | yes |
GO:0030182 | neuron differentiation | 8.0000 | 4 | yes |
GO:0030324 | lung development | 8.0000 | 4 | yes |
GO:0030855 | epithelial cell differentiation | 8.0000 | 4 | yes |
GO:0030856 | regulation of epithelial cell differentiation | 8.0000 | 5 | yes |
GO:0030858 | positive regulation of epithelial cell differentiation | 8.0000 | 6 | yes |
GO:0035315 | hair cell differentiation | 8.0000 | 5 | yes |
GO:0038001 | paracrine signaling | 8.0000 | 4 | yes |
GO:0040036 | regulation of fibroblast growth factor receptor signaling pathway | 8.0000 | 5 | yes |
GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway | 8.0000 | 6 | yes |
GO:0042060 | wound healing | 8.0000 | 4 | yes |
GO:0042490 | mechanoreceptor differentiation | 8.0000 | 5 | yes |
GO:0042491 | inner ear auditory receptor cell differentiation | 8.0000 | 6 | yes |
GO:0042660 | positive regulation of cell fate specification | 8.0000 | 6 | yes |
GO:0043491 | phosphatidylinositol 3-kinase/protein kinase B signal transduction | 8.0000 | 5 | yes |
GO:0045604 | regulation of epidermal cell differentiation | 8.0000 | 5 | yes |
GO:0045606 | positive regulation of epidermal cell differentiation | 8.0000 | 6 | yes |
GO:0045607 | regulation of inner ear auditory receptor cell differentiation | 8.0000 | 6 | yes |
GO:0045609 | positive regulation of inner ear auditory receptor cell differentiation | 8.0000 | 7 | yes |
GO:0045631 | regulation of mechanoreceptor differentiation | 8.0000 | 6 | yes |
GO:0045633 | positive regulation of mechanoreceptor differentiation | 8.0000 | 7 | yes |
GO:0045669 | positive regulation of osteoblast differentiation | 8.0000 | 6 | yes |
GO:0045682 | regulation of epidermis development | 8.0000 | 4 | yes |
GO:0045684 | positive regulation of epidermis development | 8.0000 | 5 | yes |
GO:0046668 | regulation of retinal cell programmed cell death | 8.0000 | 4 | yes |
GO:0048660 | regulation of smooth muscle cell proliferation | 8.0000 | 5 | yes |
GO:0048661 | positive regulation of smooth muscle cell proliferation | 8.0000 | 6 | yes |
GO:0048678 | response to axon injury | 8.0000 | 4 | yes |
GO:0048864 | stem cell development | 8.0000 | 4 | yes |
GO:0051209 | release of sequestered calcium ion into cytosol | 8.0000 | 6 | yes |
GO:0051283 | negative regulation of sequestering of calcium ion | 8.0000 | 5 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
SDC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SDC1_HUMAN | [view interactions] | Low throughput | no | no |
FGFR2_HUMAN | [view interactions] | Low throughput | no | yes |
RS19_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
PTX3_HUMAN | [view interactions] | Low throughput | no | no |
TSG6_HUMAN | [view interactions] | Low throughput | no | no |
PGBM_HUMAN | [view interactions] | Low throughput | no | no |
FGFR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FGFR3_HUMAN | [view interactions] | Low throughput | no | yes |
FGFP1_HUMAN | [view interactions] | Low throughput | no | no |
KALM_HUMAN | [view interactions] | Low throughput | no | no |
CASP1_HUMAN | [view interactions] | Low throughput | no | yes |
PGS2_HUMAN | [view interactions] | Low throughput | no | no |
RL6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GPC3_HUMAN | [view interactions] | Low throughput | no | no |
FGRL1_HUMAN | [view interactions] | Low throughput | no | yes |
KAPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RTN4R_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
S100B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSPG4_HUMAN | [view interactions] | Low throughput | no | yes |
SDC4_HUMAN | [view interactions] | Low throughput | no | yes |
CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSK22_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CSK2B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VTNC_HUMAN | [view interactions] | Low throughput | no | no |
SDC3_HUMAN | [view interactions] | Low throughput | no | yes |
GPC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TSP1_HUMAN | [view interactions] | Low throughput | no | no |
SPRC_HUMAN | [view interactions] | Low throughput | no | yes |
SNTG1_HUMAN | [view interactions] | Low throughput | no | no |
ANM1_HUMAN | [view interactions] | Low throughput | no | yes |
GSLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CRYAB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
FGF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
API5_HUMAN | [view interactions] | Low throughput | no | no |
TEFF1_HUMAN | [view interactions] | High throughput | no | no |
PDPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FGFR4_HUMAN | [view interactions] | High throughput | no | no |
TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IF16_HUMAN | [view interactions] | High throughput | no | no |
COMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CD44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TES_HUMAN | [view interactions] | High throughput | no | yes |
RAGE_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IL7RA_HUMAN | [view interactions] | High throughput | no | no |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
CBP_HUMAN | [view interactions] | High throughput | no | yes |
H33_HUMAN | [view interactions] | High throughput | no | yes |
MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
TAXB1_HUMAN | [view interactions] | High throughput | no | yes |