Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

FGF2_HUMAN

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed). Also acts as an integrin ligand which is required for FGF2 signaling (PubMed). Binds to integrin ITGAV:ITGB3 (PubMed). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (PubMed, PubMed). Functions as a potent mitogen in vitro (PubMed, PubMed, PubMed). Can induce angiogenesis (PubMed, PubMed). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in FGF2_HUMAN
GO:0043169 cation binding 36.0000 4 no
GO:0046872 metal ion binding 36.0000 5 no
GO:0000166 nucleotide binding 32.0000 4 no
GO:0016301 kinase activity 32.0000 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 32.0000 4 no
GO:0017076 purine nucleotide binding 32.0000 5 no
GO:0043168 anion binding 32.0000 4 no
GO:0030554 adenyl nucleotide binding 28.0000 6 no
GO:0032555 purine ribonucleotide binding 28.0000 4 no
GO:0035639 purine ribonucleoside triphosphate binding 28.0000 4 no
GO:0004674 protein serine/threonine kinase activity 24.0000 4 no
GO:0005524 ATP binding 24.0000 5 no
GO:0032559 adenyl ribonucleotide binding 24.0000 5 no
GO:0019900 kinase binding 24.0000 4 no
GO:0019901 protein kinase binding 24.0000 5 no
GO:0090722 receptor-receptor interaction 12.0000 4 yes
GO:0005104 fibroblast growth factor receptor binding 8.0000 5 yes
GO:0005125 cytokine activity 8.0000 5 yes
GO:0008083 growth factor activity 8.0000 5 yes
GO:0019956 chemokine binding 8.0000 4 yes
GO:0030374 nuclear receptor coactivator activity 8.0000 4 yes
GO:0042056 chemoattractant activity 8.0000 5 yes
GO:0048018 receptor ligand activity 8.0000 4 yes
GO:0070851 growth factor receptor binding 8.0000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in FGF2_HUMAN
GO:0009966 regulation of signal transduction 72.0000 4 yes
GO:0010646 regulation of cell communication 72.0000 4 yes
GO:0048523 negative regulation of cellular process 68.0000 4 yes
GO:0060255 regulation of macromolecule metabolic process 64.0000 4 yes
GO:0080090 regulation of primary metabolic process 64.0000 4 yes
GO:0031323 regulation of cellular metabolic process 64.0000 4 yes
GO:0048522 positive regulation of cellular process 64.0000 4 yes
GO:1902531 regulation of intracellular signal transduction 56.0000 5 yes
GO:0009892 negative regulation of metabolic process 56.0000 4 yes
GO:0010647 positive regulation of cell communication 56.0000 5 yes
GO:0023056 positive regulation of signaling 56.0000 4 yes
GO:0048584 positive regulation of response to stimulus 56.0000 4 yes
GO:0048585 negative regulation of response to stimulus 56.0000 4 yes
GO:0009967 positive regulation of signal transduction 52.0000 5 yes
GO:0051246 regulation of protein metabolic process 52.0000 5 yes
GO:1902533 positive regulation of intracellular signal transduction 48.0000 6 yes
GO:0009889 regulation of biosynthetic process 48.0000 4 yes
GO:0009893 positive regulation of metabolic process 48.0000 4 yes
GO:0009968 negative regulation of signal transduction 48.0000 5 yes
GO:0010468 regulation of gene expression 48.0000 6 yes
GO:0010556 regulation of macromolecule biosynthetic process 48.0000 5 yes
GO:0051128 regulation of cellular component organization 48.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 48.0000 5 yes
GO:0010648 negative regulation of cell communication 48.0000 5 yes
GO:0023057 negative regulation of signaling 48.0000 4 yes
GO:0031326 regulation of cellular biosynthetic process 48.0000 5 yes
GO:0031324 negative regulation of cellular metabolic process 44.0000 5 yes
GO:0043067 regulation of programmed cell death 44.0000 4 yes
GO:0045595 regulation of cell differentiation 44.0000 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 40.0000 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 40.0000 5 yes
GO:0019220 regulation of phosphate metabolic process 40.0000 6 yes
GO:0031325 positive regulation of cellular metabolic process 40.0000 5 yes
GO:0051174 regulation of phosphorus metabolic process 40.0000 5 yes
GO:0080134 regulation of response to stress 36.0000 4 yes
GO:0009890 negative regulation of biosynthetic process 36.0000 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 36.0000 6 yes
GO:0042981 regulation of apoptotic process 36.0000 5 no
GO:0022603 regulation of anatomical structure morphogenesis 36.0000 4 yes
GO:0031327 negative regulation of cellular biosynthetic process 36.0000 6 yes
GO:0032101 regulation of response to external stimulus 36.0000 4 yes
GO:0042127 regulation of cell population proliferation 36.0000 4 yes
GO:0051094 positive regulation of developmental process 36.0000 4 yes
GO:0051241 negative regulation of multicellular organismal process 36.0000 4 yes
GO:0051247 positive regulation of protein metabolic process 36.0000 6 yes
GO:0051252 regulation of RNA metabolic process 36.0000 5 yes
GO:0090304 nucleic acid metabolic process 32.0000 4 yes
GO:0001932 regulation of protein phosphorylation 32.0000 7 yes
GO:0006355 regulation of DNA-templated transcription 32.0000 7 yes
GO:2000026 regulation of multicellular organismal development 32.0000 4 yes
GO:0008284 positive regulation of cell population proliferation 32.0000 5 yes
GO:2001141 regulation of RNA biosynthetic process 32.0000 6 yes
GO:0006796 phosphate-containing compound metabolic process 32.0000 4 no
GO:0036211 protein modification process 32.0000 4 no
GO:0043412 macromolecule modification 32.0000 4 no
GO:0010629 negative regulation of gene expression 32.0000 7 yes
GO:0022607 cellular component assembly 32.0000 4 no
GO:0031399 regulation of protein modification process 32.0000 6 yes
GO:0031401 positive regulation of protein modification process 32.0000 7 yes
GO:0042325 regulation of phosphorylation 32.0000 7 yes
GO:0051240 positive regulation of multicellular organismal process 32.0000 4 yes
GO:0051726 regulation of cell cycle 28.0000 4 yes
GO:0001934 positive regulation of protein phosphorylation 28.0000 8 yes
GO:0007167 enzyme-linked receptor protein signaling pathway 28.0000 4 yes
GO:2000145 regulation of cell motility 28.0000 4 yes
GO:0009059 macromolecule biosynthetic process 28.0000 4 yes
GO:0016310 phosphorylation 28.0000 5 no
GO:0030162 regulation of proteolysis 28.0000 6 no
GO:0010562 positive regulation of phosphorus metabolic process 28.0000 6 yes
GO:0043066 negative regulation of apoptotic process 28.0000 6 no
GO:0043069 negative regulation of programmed cell death 28.0000 5 no
GO:0051248 negative regulation of protein metabolic process 28.0000 6 no
GO:2001233 regulation of apoptotic signaling pathway 28.0000 5 no
GO:0060341 regulation of cellular localization 28.0000 4 no
GO:0030334 regulation of cell migration 28.0000 5 yes
GO:0042327 positive regulation of phosphorylation 28.0000 8 yes
GO:0043408 regulation of MAPK cascade 28.0000 6 yes
GO:0045597 positive regulation of cell differentiation 28.0000 5 yes
GO:0045937 positive regulation of phosphate metabolic process 28.0000 7 yes
GO:0060284 regulation of cell development 24.0000 5 yes
GO:0090287 regulation of cellular response to growth factor stimulus 24.0000 4 yes
GO:0141124 intracellular signaling cassette 24.0000 4 yes
GO:2000147 positive regulation of cell motility 24.0000 5 yes
GO:0009891 positive regulation of biosynthetic process 24.0000 5 yes
GO:0006468 protein phosphorylation 24.0000 5 no
GO:0018193 peptidyl-amino acid modification 24.0000 5 no
GO:0010594 regulation of endothelial cell migration 24.0000 5 yes
GO:0051336 regulation of hydrolase activity 24.0000 4 no
GO:0032880 regulation of protein localization 24.0000 5 no
GO:0010632 regulation of epithelial cell migration 24.0000 4 yes
GO:0010243 response to organonitrogen compound 24.0000 4 no
GO:0071310 cellular response to organic substance 24.0000 4 no
GO:0071417 cellular response to organonitrogen compound 24.0000 4 no
GO:1901699 cellular response to nitrogen compound 24.0000 4 no
GO:1901701 cellular response to oxygen-containing compound 24.0000 4 no
GO:0030030 cell projection organization 24.0000 4 no
GO:0051049 regulation of transport 24.0000 4 no
GO:0006996 organelle organization 24.0000 4 no
GO:0043933 protein-containing complex organization 24.0000 4 no
GO:0065003 protein-containing complex assembly 24.0000 5 no
GO:0016055 Wnt signaling pathway 24.0000 4 yes
GO:0016070 RNA metabolic process 24.0000 5 yes
GO:0030335 positive regulation of cell migration 24.0000 6 yes
GO:0031328 positive regulation of cellular biosynthetic process 24.0000 6 yes
GO:0032102 negative regulation of response to external stimulus 24.0000 5 yes
GO:0032103 positive regulation of response to external stimulus 24.0000 5 yes
GO:0040017 positive regulation of locomotion 24.0000 4 yes
GO:0043085 positive regulation of catalytic activity 24.0000 4 yes
GO:0043410 positive regulation of MAPK cascade 24.0000 7 yes
GO:0043535 regulation of blood vessel endothelial cell migration 24.0000 6 yes
GO:0045927 positive regulation of growth 24.0000 4 yes
GO:0048638 regulation of developmental growth 24.0000 4 yes
GO:0070372 regulation of ERK1 and ERK2 cascade 20.0000 7 yes
GO:0070374 positive regulation of ERK1 and ERK2 cascade 20.0000 8 yes
GO:1901565 organonitrogen compound catabolic process 20.0000 4 yes
GO:0001936 regulation of endothelial cell proliferation 20.0000 6 yes
GO:0001938 positive regulation of endothelial cell proliferation 20.0000 7 yes
GO:0002009 morphogenesis of an epithelium 20.0000 4 yes
GO:0006357 regulation of transcription by RNA polymerase II 20.0000 8 yes
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 20.0000 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 20.0000 6 yes
GO:0010595 positive regulation of endothelial cell migration 20.0000 6 yes
GO:0010634 positive regulation of epithelial cell migration 20.0000 5 yes
GO:0043536 positive regulation of blood vessel endothelial cell migration 20.0000 7 yes
GO:0043549 regulation of kinase activity 20.0000 5 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 20.0000 5 yes
GO:0048639 positive regulation of developmental growth 20.0000 5 yes
GO:0050678 regulation of epithelial cell proliferation 20.0000 5 yes
GO:0050679 positive regulation of epithelial cell proliferation 20.0000 6 yes
GO:0050920 regulation of chemotaxis 20.0000 4 yes
GO:0050921 positive regulation of chemotaxis 20.0000 5 yes
GO:0051338 regulation of transferase activity 20.0000 4 yes
GO:0051347 positive regulation of transferase activity 16.0000 5 yes
GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 16.0000 6 yes
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 16.0000 7 yes
GO:0051960 regulation of nervous system development 16.0000 5 yes
GO:1901342 regulation of vasculature development 16.0000 5 yes
GO:1902680 positive regulation of RNA biosynthetic process 16.0000 7 yes
GO:0000165 MAPK cascade 16.0000 5 yes
GO:1904018 positive regulation of vasculature development 16.0000 5 yes
GO:1905562 regulation of vascular endothelial cell proliferation 16.0000 7 yes
GO:1905564 positive regulation of vascular endothelial cell proliferation 16.0000 8 yes
GO:0009057 macromolecule catabolic process 16.0000 4 yes
GO:0010628 positive regulation of gene expression 16.0000 7 yes
GO:0010720 positive regulation of cell development 16.0000 6 yes
GO:0030111 regulation of Wnt signaling pathway 16.0000 5 yes
GO:0033674 positive regulation of kinase activity 16.0000 6 yes
GO:0040013 negative regulation of locomotion 16.0000 4 yes
GO:0045664 regulation of neuron differentiation 16.0000 5 yes
GO:0045666 positive regulation of neuron differentiation 16.0000 6 yes
GO:0045765 regulation of angiogenesis 16.0000 5 yes
GO:0045766 positive regulation of angiogenesis 16.0000 6 yes
GO:0045859 regulation of protein kinase activity 16.0000 6 yes
GO:0045860 positive regulation of protein kinase activity 16.0000 7 yes
GO:0045893 positive regulation of DNA-templated transcription 16.0000 8 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 16.0000 9 yes
GO:0050767 regulation of neurogenesis 16.0000 6 yes
GO:0051052 regulation of DNA metabolic process 16.0000 5 yes
GO:0051054 positive regulation of DNA metabolic process 16.0000 6 yes
GO:0051254 positive regulation of RNA metabolic process 16.0000 6 yes
GO:0051282 regulation of sequestering of calcium ion 16.0000 4 yes
GO:0051781 positive regulation of cell division 12.0000 5 yes
GO:0051962 positive regulation of nervous system development 12.0000 5 yes
GO:0055021 regulation of cardiac muscle tissue growth 12.0000 6 yes
GO:0055023 positive regulation of cardiac muscle tissue growth 12.0000 7 yes
GO:0060043 regulation of cardiac muscle cell proliferation 12.0000 5 yes
GO:0060045 positive regulation of cardiac muscle cell proliferation 12.0000 6 yes
GO:0060420 regulation of heart growth 12.0000 5 yes
GO:0060421 positive regulation of heart growth 12.0000 6 yes
GO:0060828 regulation of canonical Wnt signaling pathway 12.0000 6 yes
GO:0060978 angiogenesis involved in coronary vascular morphogenesis 12.0000 4 yes
GO:0071900 regulation of protein serine/threonine kinase activity 12.0000 7 yes
GO:0071902 positive regulation of protein serine/threonine kinase activity 12.0000 8 yes
GO:0072091 regulation of stem cell proliferation 12.0000 5 yes
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 12.0000 7 yes
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 12.0000 8 yes
GO:0110110 positive regulation of animal organ morphogenesis 12.0000 5 yes
GO:0141187 nucleic acid biosynthetic process 12.0000 5 yes
GO:1901136 carbohydrate derivative catabolic process 12.0000 4 yes
GO:1901362 organic cyclic compound biosynthetic process 12.0000 4 yes
GO:0001667 ameboidal-type cell migration 12.0000 4 yes
GO:1903034 regulation of response to wounding 12.0000 5 yes
GO:1903035 negative regulation of response to wounding 12.0000 5 yes
GO:1903510 mucopolysaccharide metabolic process 12.0000 6 yes
GO:0002042 cell migration involved in sprouting angiogenesis 12.0000 8 yes
GO:1903670 regulation of sprouting angiogenesis 12.0000 6 yes
GO:1903672 positive regulation of sprouting angiogenesis 12.0000 7 yes
GO:0003156 regulation of animal organ formation 12.0000 6 yes
GO:0006022 aminoglycan metabolic process 12.0000 4 yes
GO:1904847 regulation of cell chemotaxis to fibroblast growth factor 12.0000 5 yes
GO:0006026 aminoglycan catabolic process 12.0000 5 yes
GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor 12.0000 6 yes
GO:0006027 glycosaminoglycan catabolic process 12.0000 6 yes
GO:0006351 DNA-templated transcription 12.0000 6 yes
GO:1905330 regulation of morphogenesis of an epithelium 12.0000 5 yes
GO:0006366 transcription by RNA polymerase II 12.0000 7 yes
GO:2000027 regulation of animal organ morphogenesis 12.0000 5 yes
GO:2000146 negative regulation of cell motility 12.0000 5 yes
GO:0008285 negative regulation of cell population proliferation 12.0000 5 yes
GO:2000544 regulation of endothelial cell chemotaxis to fibroblast growth factor 12.0000 6 yes
GO:0008543 fibroblast growth factor receptor signaling pathway 12.0000 6 yes
GO:2000546 positive regulation of endothelial cell chemotaxis to fibroblast growth factor 12.0000 7 yes
GO:0009792 embryo development ending in birth or egg hatching 12.0000 4 yes
GO:2000648 positive regulation of stem cell proliferation 12.0000 6 yes
GO:2001026 regulation of endothelial cell chemotaxis 12.0000 5 yes
GO:2001028 positive regulation of endothelial cell chemotaxis 12.0000 6 yes
GO:0010453 regulation of cell fate commitment 12.0000 4 yes
GO:0010596 negative regulation of endothelial cell migration 12.0000 6 yes
GO:0010631 epithelial cell migration 12.0000 5 yes
GO:0010633 negative regulation of epithelial cell migration 12.0000 5 yes
GO:0030177 positive regulation of Wnt signaling pathway 12.0000 6 yes
GO:0030203 glycosaminoglycan metabolic process 12.0000 5 yes
GO:0030212 hyaluronan metabolic process 12.0000 7 yes
GO:0030214 hyaluronan catabolic process 12.0000 7 yes
GO:0030336 negative regulation of cell migration 12.0000 6 yes
GO:0032774 RNA biosynthetic process 12.0000 5 yes
GO:0034654 nucleobase-containing compound biosynthetic process 12.0000 4 yes
GO:0042659 regulation of cell fate specification 12.0000 5 yes
GO:0043405 regulation of MAP kinase activity 12.0000 8 yes
GO:0043406 positive regulation of MAP kinase activity 12.0000 8 yes
GO:0043534 blood vessel endothelial cell migration 12.0000 7 yes
GO:0043537 negative regulation of blood vessel endothelial cell migration 12.0000 7 yes
GO:0043542 endothelial cell migration 12.0000 6 yes
GO:0045667 regulation of osteoblast differentiation 12.0000 5 yes
GO:0046620 regulation of organ growth 12.0000 4 yes
GO:0046622 positive regulation of organ growth 12.0000 5 yes
GO:0048754 branching morphogenesis of an epithelial tube 12.0000 4 yes
GO:0050769 positive regulation of neurogenesis 12.0000 6 yes
GO:0051302 regulation of cell division 12.0000 4 yes
GO:0060070 canonical Wnt signaling pathway 8.0000 5 yes
GO:0060113 inner ear receptor cell differentiation 8.0000 6 yes
GO:0060128 corticotropin hormone secreting cell differentiation 8.0000 4 yes
GO:0060129 thyroid-stimulating hormone-secreting cell differentiation 8.0000 6 yes
GO:0060563 neuroepithelial cell differentiation 8.0000 6 yes
GO:0060591 chondroblast differentiation 8.0000 4 yes
GO:0060644 mammary gland epithelial cell differentiation 8.0000 5 yes
GO:0061041 regulation of wound healing 8.0000 6 yes
GO:0061045 negative regulation of wound healing 8.0000 6 yes
GO:0061101 neuroendocrine cell differentiation 8.0000 5 yes
GO:0070371 ERK1 and ERK2 cascade 8.0000 6 yes
GO:0070588 calcium ion transmembrane transport 8.0000 5 yes
GO:0071260 cellular response to mechanical stimulus 8.0000 4 yes
GO:0090263 positive regulation of canonical Wnt signaling pathway 8.0000 7 yes
GO:0090288 negative regulation of cellular response to growth factor stimulus 8.0000 5 yes
GO:0097553 calcium ion transmembrane import into cytosol 8.0000 6 yes
GO:0098655 monoatomic cation transmembrane transport 8.0000 4 yes
GO:0098662 inorganic cation transmembrane transport 8.0000 4 yes
GO:1902692 regulation of neuroblast proliferation 8.0000 6 yes
GO:0001649 osteoblast differentiation 8.0000 4 yes
GO:1902746 regulation of lens fiber cell differentiation 8.0000 6 yes
GO:0001658 branching involved in ureteric bud morphogenesis 8.0000 5 yes
GO:1902748 positive regulation of lens fiber cell differentiation 8.0000 5 yes
GO:1902893 regulation of miRNA transcription 8.0000 7 yes
GO:1902895 positive regulation of miRNA transcription 8.0000 8 yes
GO:1902913 positive regulation of neuroepithelial cell differentiation 8.0000 7 yes
GO:0001935 endothelial cell proliferation 8.0000 4 yes
GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 8.0000 7 yes
GO:0002052 positive regulation of neuroblast proliferation 8.0000 7 yes
GO:0002065 columnar/cuboidal epithelial cell differentiation 8.0000 5 yes
GO:0002067 glandular epithelial cell differentiation 8.0000 6 yes
GO:1904705 regulation of vascular associated smooth muscle cell proliferation 8.0000 6 yes
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 8.0000 7 yes
GO:1904977 lymphatic endothelial cell migration 8.0000 7 yes
GO:1905276 regulation of epithelial tube formation 8.0000 5 yes
GO:1905278 positive regulation of epithelial tube formation 8.0000 5 yes
GO:1905332 positive regulation of morphogenesis of an epithelium 8.0000 5 yes
GO:0006811 monoatomic ion transport 8.0000 4 yes
GO:0006812 monoatomic cation transport 8.0000 5 yes
GO:0006816 calcium ion transport 8.0000 7 yes
GO:0007264 small GTPase-mediated signal transduction 8.0000 5 yes
GO:0007265 Ras protein signal transduction 8.0000 6 yes
GO:0007399 nervous system development 8.0000 4 yes
GO:2000177 regulation of neural precursor cell proliferation 8.0000 5 yes
GO:0007405 neuroblast proliferation 8.0000 4 yes
GO:2000179 positive regulation of neural precursor cell proliferation 8.0000 6 yes
GO:2000278 regulation of DNA biosynthetic process 8.0000 6 yes
GO:2000573 positive regulation of DNA biosynthetic process 8.0000 7 yes
GO:2000628 regulation of miRNA metabolic process 8.0000 6 yes
GO:2000630 positive regulation of miRNA metabolic process 8.0000 7 yes
GO:2000647 negative regulation of stem cell proliferation 8.0000 6 yes
GO:2000736 regulation of stem cell differentiation 8.0000 5 yes
GO:2000738 positive regulation of stem cell differentiation 8.0000 6 yes
GO:2000980 regulation of inner ear receptor cell differentiation 8.0000 7 yes
GO:0009913 epidermal cell differentiation 8.0000 5 yes
GO:2000982 positive regulation of inner ear receptor cell differentiation 8.0000 8 yes
GO:0010001 glial cell differentiation 8.0000 4 yes
GO:0010455 positive regulation of cell fate commitment 8.0000 5 yes
GO:0010762 regulation of fibroblast migration 8.0000 6 yes
GO:0010764 negative regulation of fibroblast migration 8.0000 7 yes
GO:0014842 regulation of skeletal muscle satellite cell proliferation 8.0000 6 yes
GO:0014843 growth factor dependent regulation of skeletal muscle satellite cell proliferation 8.0000 7 yes
GO:0014857 regulation of skeletal muscle cell proliferation 8.0000 5 yes
GO:0021534 cell proliferation in hindbrain 8.0000 4 yes
GO:0021762 substantia nigra development 8.0000 4 yes
GO:0021924 cell proliferation in external granule layer 8.0000 5 yes
GO:0021930 cerebellar granule cell precursor proliferation 8.0000 6 yes
GO:0021936 regulation of cerebellar granule cell precursor proliferation 8.0000 6 yes
GO:0021940 positive regulation of cerebellar granule cell precursor proliferation 8.0000 7 yes
GO:0030001 metal ion transport 8.0000 6 yes
GO:0030182 neuron differentiation 8.0000 4 yes
GO:0030324 lung development 8.0000 4 yes
GO:0030855 epithelial cell differentiation 8.0000 4 yes
GO:0030856 regulation of epithelial cell differentiation 8.0000 5 yes
GO:0030858 positive regulation of epithelial cell differentiation 8.0000 6 yes
GO:0035315 hair cell differentiation 8.0000 5 yes
GO:0038001 paracrine signaling 8.0000 4 yes
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 8.0000 5 yes
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 8.0000 6 yes
GO:0042060 wound healing 8.0000 4 yes
GO:0042490 mechanoreceptor differentiation 8.0000 5 yes
GO:0042491 inner ear auditory receptor cell differentiation 8.0000 6 yes
GO:0042660 positive regulation of cell fate specification 8.0000 6 yes
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction 8.0000 5 yes
GO:0045604 regulation of epidermal cell differentiation 8.0000 5 yes
GO:0045606 positive regulation of epidermal cell differentiation 8.0000 6 yes
GO:0045607 regulation of inner ear auditory receptor cell differentiation 8.0000 6 yes
GO:0045609 positive regulation of inner ear auditory receptor cell differentiation 8.0000 7 yes
GO:0045631 regulation of mechanoreceptor differentiation 8.0000 6 yes
GO:0045633 positive regulation of mechanoreceptor differentiation 8.0000 7 yes
GO:0045669 positive regulation of osteoblast differentiation 8.0000 6 yes
GO:0045682 regulation of epidermis development 8.0000 4 yes
GO:0045684 positive regulation of epidermis development 8.0000 5 yes
GO:0046668 regulation of retinal cell programmed cell death 8.0000 4 yes
GO:0048660 regulation of smooth muscle cell proliferation 8.0000 5 yes
GO:0048661 positive regulation of smooth muscle cell proliferation 8.0000 6 yes
GO:0048678 response to axon injury 8.0000 4 yes
GO:0048864 stem cell development 8.0000 4 yes
GO:0051209 release of sequestered calcium ion into cytosol 8.0000 6 yes
GO:0051283 negative regulation of sequestering of calcium ion 8.0000 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SDC2_HUMAN [view entry] [view interactions] Low throughput yes yes
SDC1_HUMAN [view interactions] Low throughput no no
FGFR2_HUMAN [view interactions] Low throughput no yes
RS19_HUMAN [view entry] [view interactions] Low throughput yes no
PTX3_HUMAN [view interactions] Low throughput no no
TSG6_HUMAN [view interactions] Low throughput no no
PGBM_HUMAN [view interactions] Low throughput no no
FGFR1_HUMAN [view entry] [view interactions] Low throughput yes yes
FGFR3_HUMAN [view interactions] Low throughput no yes
FGFP1_HUMAN [view interactions] Low throughput no no
KALM_HUMAN [view interactions] Low throughput no no
CASP1_HUMAN [view interactions] Low throughput no yes
PGS2_HUMAN [view interactions] Low throughput no no
RL6_HUMAN [view entry] [view interactions] Low throughput yes yes
GPC3_HUMAN [view interactions] Low throughput no no
FGRL1_HUMAN [view interactions] Low throughput no yes
KAPCA_HUMAN [view entry] [view interactions] Low throughput yes yes
RTN4R_HUMAN [view entry] [view interactions] Low throughput yes no
S100B_HUMAN [view entry] [view interactions] Low throughput yes yes
CSPG4_HUMAN [view interactions] Low throughput no yes
SDC4_HUMAN [view interactions] Low throughput no yes
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
CSK22_HUMAN [view entry] [view interactions] Low throughput yes no
CSK2B_HUMAN [view entry] [view interactions] Low throughput yes yes
VTNC_HUMAN [view interactions] Low throughput no no
SDC3_HUMAN [view interactions] Low throughput no yes
GPC4_HUMAN [view entry] [view interactions] Low throughput yes yes
TSP1_HUMAN [view interactions] Low throughput no no
SPRC_HUMAN [view interactions] Low throughput no yes
SNTG1_HUMAN [view interactions] Low throughput no no
ANM1_HUMAN [view interactions] Low throughput no yes
GSLG1_HUMAN [view entry] [view interactions] Low throughput yes yes
NRP1_HUMAN [view entry] [view interactions] Low throughput yes yes
CRYAB_HUMAN [view entry] [view interactions] Low throughput yes no
FGF2_HUMAN [view entry] [view interactions] Low throughput yes yes
API5_HUMAN [view interactions] Low throughput no no
TEFF1_HUMAN [view interactions] High throughput no no
PDPK1_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR4_HUMAN [view interactions] High throughput no no
TBG1_HUMAN [view entry] [view interactions] High throughput yes yes
IF16_HUMAN [view interactions] High throughput no no
COMT_HUMAN [view entry] [view interactions] High throughput yes yes
CD44_HUMAN [view entry] [view interactions] High throughput yes yes
TES_HUMAN [view interactions] High throughput no yes
RAGE_HUMAN [view entry] [view interactions] High throughput yes no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
IL7RA_HUMAN [view interactions] High throughput no no
PARP1_HUMAN [view entry] [view interactions] High throughput yes yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
UBE2O_HUMAN [view interactions] High throughput no yes
NR4A1_HUMAN [view interactions] High throughput no yes
CBP_HUMAN [view interactions] High throughput no yes
H33_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
TAXB1_HUMAN [view interactions] High throughput no yes