Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

FGF2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed). Also acts as an integrin ligand which is required for FGF2 signaling (PubMed). Binds to integrin ITGAV:ITGB3 (PubMed). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (PubMed, PubMed). Functions as a potent mitogen in vitro (PubMed, PubMed, PubMed). Can induce angiogenesis (PubMed, PubMed). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in FGF2_HUMAN
GO:0017076 purine nucleotide binding 40.6250 4 no
GO:0032555 purine ribonucleotide binding 40.6250 4 no
GO:0035639 purine ribonucleoside triphosphate binding 40.6250 4 no
GO:0016301 kinase activity 34.3750 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 34.3750 4 no
GO:0046872 metal ion binding 28.1250 4 no
GO:0004712 protein serine/threonine/tyrosine kinase activity 28.1250 4 no
GO:0005524 ATP binding 28.1250 5 no
GO:0030554 adenyl nucleotide binding 28.1250 5 no
GO:0032559 adenyl ribonucleotide binding 28.1250 5 no
GO:0004674 protein serine/threonine kinase activity 25.0000 4 no
GO:0106310 protein serine kinase activity 21.8750 4 no
GO:0008083 growth factor activity 9.3750 5 yes
GO:0048018 receptor ligand activity 9.3750 4 yes
GO:0070851 growth factor receptor binding 9.3750 4 yes
GO:0005104 fibroblast growth factor receptor binding 6.2500 5 yes
GO:0005125 cytokine activity 6.2500 5 yes
GO:0019956 chemokine binding 6.2500 4 yes
GO:0030374 nuclear receptor coactivator activity 6.2500 4 yes
GO:0042056 chemoattractant activity 6.2500 5 yes
GO:0090722 receptor-receptor interaction 6.2500 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in FGF2_HUMAN
GO:0010646 regulation of cell communication 75.0000 4 yes
GO:0048522 positive regulation of cellular process 75.0000 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 75.0000 4 yes
GO:0060255 regulation of macromolecule metabolic process 75.0000 4 yes
GO:0080090 regulation of primary metabolic process 75.0000 4 yes
GO:0009966 regulation of signal transduction 75.0000 4 yes
GO:0031323 regulation of cellular metabolic process 71.8750 4 yes
GO:0048523 negative regulation of cellular process 65.6250 4 yes
GO:0051246 regulation of protein metabolic process 65.6250 5 yes
GO:0042127 regulation of cell population proliferation 59.3750 4 yes
GO:0009893 positive regulation of metabolic process 59.3750 4 yes
GO:0010468 regulation of gene expression 56.2500 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 56.2500 5 yes
GO:0048584 positive regulation of response to stimulus 56.2500 4 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 56.2500 5 yes
GO:0008284 positive regulation of cell population proliferation 56.2500 5 yes
GO:0010647 positive regulation of cell communication 53.1250 5 yes
GO:0023056 positive regulation of signaling 53.1250 4 yes
GO:0031325 positive regulation of cellular metabolic process 53.1250 5 yes
GO:0051247 positive regulation of protein metabolic process 53.1250 6 yes
GO:0009967 positive regulation of signal transduction 50.0000 5 yes
GO:0019220 regulation of phosphate metabolic process 46.8750 6 yes
GO:0042325 regulation of phosphorylation 46.8750 7 yes
GO:0045595 regulation of cell differentiation 46.8750 4 yes
GO:0051174 regulation of phosphorus metabolic process 46.8750 5 yes
GO:0051128 regulation of cellular component organization 46.8750 4 no
GO:0010562 positive regulation of phosphorus metabolic process 43.7500 6 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 43.7500 5 yes
GO:0031399 regulation of protein modification process 43.7500 6 yes
GO:0031401 positive regulation of protein modification process 43.7500 7 yes
GO:0042327 positive regulation of phosphorylation 43.7500 8 yes
GO:0043085 positive regulation of catalytic activity 43.7500 4 yes
GO:0045937 positive regulation of phosphate metabolic process 43.7500 7 yes
GO:1902531 regulation of intracellular signal transduction 43.7500 5 yes
GO:0001932 regulation of protein phosphorylation 43.7500 7 yes
GO:0001934 positive regulation of protein phosphorylation 43.7500 8 yes
GO:0009892 negative regulation of metabolic process 43.7500 4 yes
GO:0060341 regulation of cellular localization 40.6250 4 no
GO:0010556 regulation of macromolecule biosynthetic process 40.6250 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 40.6250 5 yes
GO:0030334 regulation of cell migration 40.6250 5 yes
GO:0031326 regulation of cellular biosynthetic process 40.6250 5 yes
GO:0048585 negative regulation of response to stimulus 40.6250 4 yes
GO:0051252 regulation of RNA metabolic process 40.6250 5 yes
GO:0051336 regulation of hydrolase activity 40.6250 4 yes
GO:2000145 regulation of cell motility 40.6250 4 yes
GO:0006796 phosphate-containing compound metabolic process 40.6250 4 yes
GO:0009889 regulation of biosynthetic process 40.6250 4 yes
GO:0010648 negative regulation of cell communication 37.5000 5 yes
GO:0010941 regulation of cell death 37.5000 4 yes
GO:0023057 negative regulation of signaling 37.5000 4 yes
GO:0043067 regulation of programmed cell death 37.5000 5 yes
GO:0051240 positive regulation of multicellular organismal process 37.5000 4 yes
GO:1903506 regulation of nucleic acid-templated transcription 37.5000 7 yes
GO:2000026 regulation of multicellular organismal development 37.5000 4 yes
GO:0006355 regulation of DNA-templated transcription 37.5000 6 yes
GO:2001141 regulation of RNA biosynthetic process 37.5000 6 yes
GO:0009968 negative regulation of signal transduction 37.5000 5 yes
GO:0071310 cellular response to organic substance 34.3750 4 no
GO:0016310 phosphorylation 34.3750 5 no
GO:0010628 positive regulation of gene expression 34.3750 6 yes
GO:0030335 positive regulation of cell migration 34.3750 6 yes
GO:0040017 positive regulation of locomotion 34.3750 4 yes
GO:0050678 regulation of epithelial cell proliferation 34.3750 5 yes
GO:0051094 positive regulation of developmental process 34.3750 4 yes
GO:0051338 regulation of transferase activity 34.3750 4 yes
GO:0051347 positive regulation of transferase activity 34.3750 5 yes
GO:0060548 negative regulation of cell death 34.3750 5 yes
GO:1902533 positive regulation of intracellular signal transduction 34.3750 6 yes
GO:2000147 positive regulation of cell motility 34.3750 5 yes
GO:0051049 regulation of transport 34.3750 4 no
GO:0006468 protein phosphorylation 31.2500 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 31.2500 6 yes
GO:0036211 protein modification process 31.2500 4 no
GO:0043412 macromolecule modification 31.2500 4 no
GO:0031328 positive regulation of cellular biosynthetic process 31.2500 6 yes
GO:0043408 regulation of MAPK cascade 31.2500 6 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 31.2500 6 yes
GO:0050679 positive regulation of epithelial cell proliferation 31.2500 6 yes
GO:0007167 enzyme-linked receptor protein signaling pathway 31.2500 4 yes
GO:0032880 regulation of protein localization 31.2500 5 no
GO:0042981 regulation of apoptotic process 31.2500 6 no
GO:0009891 positive regulation of biosynthetic process 31.2500 5 yes
GO:0018193 peptidyl-amino acid modification 28.1250 5 no
GO:0033674 positive regulation of kinase activity 28.1250 6 yes
GO:0043410 positive regulation of MAPK cascade 28.1250 7 yes
GO:0043549 regulation of kinase activity 28.1250 5 yes
GO:0045893 positive regulation of DNA-templated transcription 28.1250 7 yes
GO:0051241 negative regulation of multicellular organismal process 28.1250 4 yes
GO:0051254 positive regulation of RNA metabolic process 28.1250 6 yes
GO:0051345 positive regulation of hydrolase activity 28.1250 5 yes
GO:0051726 regulation of cell cycle 28.1250 4 yes
GO:1902680 positive regulation of RNA biosynthetic process 28.1250 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 28.1250 8 yes
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 28.1250 5 yes
GO:0010243 response to organonitrogen compound 28.1250 4 no
GO:0043066 negative regulation of apoptotic process 28.1250 7 no
GO:0043069 negative regulation of programmed cell death 28.1250 6 no
GO:0051172 negative regulation of nitrogen compound metabolic process 28.1250 5 no
GO:0010001 glial cell differentiation 25.0000 4 yes
GO:0071417 cellular response to organonitrogen compound 25.0000 4 no
GO:1901699 cellular response to nitrogen compound 25.0000 4 no
GO:1901701 cellular response to oxygen-containing compound 25.0000 4 no
GO:0010629 negative regulation of gene expression 25.0000 6 yes
GO:0030162 regulation of proteolysis 25.0000 6 no
GO:0022603 regulation of anatomical structure morphogenesis 25.0000 4 yes
GO:0032101 regulation of response to external stimulus 25.0000 4 yes
GO:0045597 positive regulation of cell differentiation 25.0000 5 yes
GO:0045859 regulation of protein kinase activity 25.0000 6 yes
GO:0045860 positive regulation of protein kinase activity 25.0000 7 yes
GO:0070372 regulation of ERK1 and ERK2 cascade 25.0000 7 yes
GO:0080134 regulation of response to stress 25.0000 4 yes
GO:0001936 regulation of endothelial cell proliferation 25.0000 6 yes
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 no
GO:0051093 negative regulation of developmental process 25.0000 4 no
GO:0051248 negative regulation of protein metabolic process 25.0000 6 no
GO:1903829 positive regulation of protein localization 21.8750 5 no
GO:0018107 peptidyl-threonine phosphorylation 21.8750 6 no
GO:0018210 peptidyl-threonine modification 21.8750 6 no
GO:0022607 cellular component assembly 21.8750 4 no
GO:0044087 regulation of cellular component biogenesis 21.8750 4 no
GO:0006996 organelle organization 21.8750 4 no
GO:0006915 apoptotic process 21.8750 4 no
GO:0032386 regulation of intracellular transport 21.8750 5 no
GO:0050804 modulation of chemical synaptic transmission 21.8750 5 no
GO:0099177 regulation of trans-synaptic signaling 21.8750 4 no
GO:0032103 positive regulation of response to external stimulus 21.8750 5 yes
GO:0045927 positive regulation of growth 21.8750 4 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 21.8750 8 yes
GO:0070374 positive regulation of ERK1 and ERK2 cascade 21.8750 8 yes
GO:0090287 regulation of cellular response to growth factor stimulus 21.8750 4 yes
GO:0001938 positive regulation of endothelial cell proliferation 21.8750 7 yes
GO:0006357 regulation of transcription by RNA polymerase II 21.8750 7 yes
GO:0007264 small GTPase mediated signal transduction 21.8750 4 yes
GO:0007265 Ras protein signal transduction 21.8750 5 yes
GO:0000165 MAPK cascade 21.8750 4 no
GO:0002684 positive regulation of immune system process 21.8750 4 no
GO:0008285 negative regulation of cell population proliferation 21.8750 5 yes
GO:0033043 regulation of organelle organization 21.8750 5 no
GO:0045596 negative regulation of cell differentiation 21.8750 5 no
GO:0051130 positive regulation of cellular component organization 21.8750 5 no
GO:0010594 regulation of endothelial cell migration 18.7500 5 yes
GO:0010632 regulation of epithelial cell migration 18.7500 4 yes
GO:0040013 negative regulation of locomotion 18.7500 4 yes
GO:0045765 regulation of angiogenesis 18.7500 5 yes
GO:0048638 regulation of developmental growth 18.7500 4 yes
GO:0050920 regulation of chemotaxis 18.7500 4 yes
GO:0050921 positive regulation of chemotaxis 18.7500 5 yes
GO:1901342 regulation of vasculature development 18.7500 5 yes
GO:0010595 positive regulation of endothelial cell migration 15.6250 6 yes
GO:0010634 positive regulation of epithelial cell migration 15.6250 5 yes
GO:0030336 negative regulation of cell migration 15.6250 6 yes
GO:0032102 negative regulation of response to external stimulus 15.6250 5 yes
GO:0042060 wound healing 15.6250 4 yes
GO:0043405 regulation of MAP kinase activity 15.6250 8 yes
GO:0043406 positive regulation of MAP kinase activity 15.6250 8 yes
GO:0043535 regulation of blood vessel endothelial cell migration 15.6250 6 yes
GO:0045766 positive regulation of angiogenesis 15.6250 6 yes
GO:0048639 positive regulation of developmental growth 15.6250 5 yes
GO:0071900 regulation of protein serine/threonine kinase activity 15.6250 7 yes
GO:0071902 positive regulation of protein serine/threonine kinase activity 15.6250 8 yes
GO:1904018 positive regulation of vasculature development 15.6250 5 yes
GO:0002009 morphogenesis of an epithelium 15.6250 4 yes
GO:2000146 negative regulation of cell motility 15.6250 5 yes
GO:2000628 regulation of miRNA metabolic process 15.6250 6 yes
GO:2000630 positive regulation of miRNA metabolic process 15.6250 7 yes
GO:0010517 regulation of phospholipase activity 12.5000 6 yes
GO:0010518 positive regulation of phospholipase activity 12.5000 7 yes
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 12.5000 6 yes
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 12.5000 7 yes
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 12.5000 5 yes
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 12.5000 6 yes
GO:0043536 positive regulation of blood vessel endothelial cell migration 12.5000 7 yes
GO:0045667 regulation of osteoblast differentiation 12.5000 5 yes
GO:0048754 branching morphogenesis of an epithelial tube 12.5000 4 yes
GO:0048864 stem cell development 12.5000 4 yes
GO:0051052 regulation of DNA metabolic process 12.5000 5 yes
GO:0051054 positive regulation of DNA metabolic process 12.5000 6 yes
GO:0051282 regulation of sequestering of calcium ion 12.5000 4 yes
GO:0060191 regulation of lipase activity 12.5000 5 yes
GO:0060193 positive regulation of lipase activity 12.5000 6 yes
GO:0090288 negative regulation of cellular response to growth factor stimulus 12.5000 5 yes
GO:1901565 organonitrogen compound catabolic process 12.5000 4 yes
GO:1902893 regulation of miRNA transcription 12.5000 7 yes
GO:1902895 positive regulation of miRNA transcription 12.5000 8 yes
GO:1905562 regulation of vascular endothelial cell proliferation 12.5000 7 yes
GO:1905564 positive regulation of vascular endothelial cell proliferation 12.5000 8 yes
GO:2000278 regulation of DNA biosynthetic process 12.5000 6 yes
GO:2000573 positive regulation of DNA biosynthetic process 12.5000 7 yes
GO:0010596 negative regulation of endothelial cell migration 9.3750 6 yes
GO:0010631 epithelial cell migration 9.3750 5 yes
GO:0010633 negative regulation of epithelial cell migration 9.3750 5 yes
GO:0010863 positive regulation of phospholipase C activity 9.3750 8 yes
GO:0030111 regulation of Wnt signaling pathway 9.3750 5 yes
GO:0030177 positive regulation of Wnt signaling pathway 9.3750 6 yes
GO:0043534 blood vessel endothelial cell migration 9.3750 7 yes
GO:0043537 negative regulation of blood vessel endothelial cell migration 9.3750 7 yes
GO:0043542 endothelial cell migration 9.3750 6 yes
GO:0045669 positive regulation of osteoblast differentiation 9.3750 6 yes
GO:0046620 regulation of organ growth 9.3750 4 yes
GO:0046622 positive regulation of organ growth 9.3750 5 yes
GO:0048660 regulation of smooth muscle cell proliferation 9.3750 5 yes
GO:0048661 positive regulation of smooth muscle cell proliferation 9.3750 6 yes
GO:0051302 regulation of cell division 9.3750 4 yes
GO:0051781 positive regulation of cell division 9.3750 5 yes
GO:0051896 regulation of protein kinase B signaling 9.3750 6 yes
GO:0055021 regulation of cardiac muscle tissue growth 9.3750 6 yes
GO:0055023 positive regulation of cardiac muscle tissue growth 9.3750 7 yes
GO:0060420 regulation of heart growth 9.3750 5 yes
GO:0060421 positive regulation of heart growth 9.3750 6 yes
GO:0060978 angiogenesis involved in coronary vascular morphogenesis 9.3750 4 yes
GO:0061041 regulation of wound healing 9.3750 6 yes
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 9.3750 7 yes
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 9.3750 8 yes
GO:0110110 positive regulation of animal organ morphogenesis 9.3750 5 yes
GO:1900274 regulation of phospholipase C activity 9.3750 7 yes
GO:1901136 carbohydrate derivative catabolic process 9.3750 4 yes
GO:1903034 regulation of response to wounding 9.3750 5 yes
GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 9.3750 7 yes
GO:1903670 regulation of sprouting angiogenesis 9.3750 6 yes
GO:1903672 positive regulation of sprouting angiogenesis 9.3750 7 yes
GO:1904705 regulation of vascular associated smooth muscle cell proliferation 9.3750 6 yes
GO:0001667 ameboidal-type cell migration 9.3750 4 yes
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 9.3750 7 yes
GO:0002042 cell migration involved in sprouting angiogenesis 9.3750 8 yes
GO:2000027 regulation of animal organ morphogenesis 9.3750 5 yes
GO:0006811 ion transport 9.3750 4 yes
GO:0007399 nervous system development 9.3750 4 yes
GO:0009057 macromolecule catabolic process 9.3750 4 yes
GO:0010453 regulation of cell fate commitment 6.2500 4 yes
GO:0010455 positive regulation of cell fate commitment 6.2500 5 yes
GO:0010762 regulation of fibroblast migration 6.2500 6 yes
GO:0010764 negative regulation of fibroblast migration 6.2500 7 yes
GO:0014842 regulation of skeletal muscle satellite cell proliferation 6.2500 6 yes
GO:0014843 growth factor dependent regulation of skeletal muscle satellite cell proliferation 6.2500 7 yes
GO:0014857 regulation of skeletal muscle cell proliferation 6.2500 5 yes
GO:0019216 regulation of lipid metabolic process 6.2500 5 yes
GO:0019751 polyol metabolic process 6.2500 4 yes
GO:0021762 substantia nigra development 6.2500 4 yes
GO:0021936 regulation of cerebellar granule cell precursor proliferation 6.2500 6 yes
GO:0021940 positive regulation of cerebellar granule cell precursor proliferation 6.2500 7 yes
GO:0030001 metal ion transport 6.2500 6 yes
GO:0030203 glycosaminoglycan metabolic process 6.2500 5 yes
GO:0030212 hyaluronan metabolic process 6.2500 7 yes
GO:0030214 hyaluronan catabolic process 6.2500 7 yes
GO:0030324 lung development 6.2500 4 yes
GO:0030855 epithelial cell differentiation 6.2500 4 yes
GO:0030856 regulation of epithelial cell differentiation 6.2500 5 yes
GO:0030858 positive regulation of epithelial cell differentiation 6.2500 6 yes
GO:0032958 inositol phosphate biosynthetic process 6.2500 5 yes
GO:0042659 regulation of cell fate specification 6.2500 5 yes
GO:0042660 positive regulation of cell fate specification 6.2500 6 yes
GO:0043550 regulation of lipid kinase activity 6.2500 6 yes
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 6.2500 7 yes
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 6.2500 7 yes
GO:0043647 inositol phosphate metabolic process 6.2500 4 yes
GO:0045017 glycerolipid biosynthetic process 6.2500 4 yes
GO:0045834 positive regulation of lipid metabolic process 6.2500 5 yes
GO:0046165 alcohol biosynthetic process 6.2500 4 yes
GO:0046173 polyol biosynthetic process 6.2500 5 yes
GO:0046474 glycerophospholipid biosynthetic process 6.2500 5 yes
GO:0046486 glycerolipid metabolic process 6.2500 4 yes
GO:0046488 phosphatidylinositol metabolic process 6.2500 6 yes
GO:0046668 regulation of retinal cell programmed cell death 6.2500 4 yes
GO:0048678 response to axon injury 6.2500 4 yes
GO:0051209 release of sequestered calcium ion into cytosol 6.2500 6 yes
GO:0051283 negative regulation of sequestering of calcium ion 6.2500 5 yes
GO:0051897 positive regulation of protein kinase B signaling 6.2500 7 yes
GO:0060043 regulation of cardiac muscle cell proliferation 6.2500 5 yes
GO:0060045 positive regulation of cardiac muscle cell proliferation 6.2500 6 yes
GO:0060128 corticotropin hormone secreting cell differentiation 6.2500 4 yes
GO:0060129 thyroid-stimulating hormone-secreting cell differentiation 6.2500 7 yes
GO:0060563 neuroepithelial cell differentiation 6.2500 6 yes
GO:0060591 chondroblast differentiation 6.2500 4 yes
GO:0060644 mammary gland epithelial cell differentiation 6.2500 5 yes
GO:0060828 regulation of canonical Wnt signaling pathway 6.2500 6 yes
GO:0061045 negative regulation of wound healing 6.2500 6 yes
GO:0061101 neuroendocrine cell differentiation 6.2500 7 yes
GO:0070588 calcium ion transmembrane transport 6.2500 6 yes
GO:0090218 positive regulation of lipid kinase activity 6.2500 6 yes
GO:0090263 positive regulation of canonical Wnt signaling pathway 6.2500 7 yes
GO:0090407 organophosphate biosynthetic process 6.2500 4 yes
GO:0097553 calcium ion transmembrane import into cytosol 6.2500 7 yes
GO:0098655 cation transmembrane transport 6.2500 4 yes
GO:0098660 inorganic ion transmembrane transport 6.2500 4 yes
GO:0098662 inorganic cation transmembrane transport 6.2500 5 yes
GO:1901617 organic hydroxy compound biosynthetic process 6.2500 4 yes
GO:1902746 regulation of lens fiber cell differentiation 6.2500 6 yes
GO:1902748 positive regulation of lens fiber cell differentiation 6.2500 5 yes
GO:1903035 negative regulation of response to wounding 6.2500 5 yes
GO:1903510 mucopolysaccharide metabolic process 6.2500 6 yes
GO:0001658 branching involved in ureteric bud morphogenesis 6.2500 5 yes
GO:1904847 regulation of cell chemotaxis to fibroblast growth factor 6.2500 5 yes
GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor 6.2500 6 yes
GO:1905276 regulation of epithelial tube formation 6.2500 5 yes
GO:1905278 positive regulation of epithelial tube formation 6.2500 5 yes
GO:1905330 regulation of morphogenesis of an epithelium 6.2500 5 yes
GO:1905332 positive regulation of morphogenesis of an epithelium 6.2500 5 yes
GO:0002065 columnar/cuboidal epithelial cell differentiation 6.2500 5 yes
GO:0002067 glandular epithelial cell differentiation 6.2500 6 yes
GO:0003156 regulation of animal organ formation 6.2500 6 yes
GO:0006022 aminoglycan metabolic process 6.2500 4 yes
GO:0006026 aminoglycan catabolic process 6.2500 5 yes
GO:0006027 glycosaminoglycan catabolic process 6.2500 6 yes
GO:2000177 regulation of neural precursor cell proliferation 6.2500 5 yes
GO:0006644 phospholipid metabolic process 6.2500 4 yes
GO:2000179 positive regulation of neural precursor cell proliferation 6.2500 6 yes
GO:0006650 glycerophospholipid metabolic process 6.2500 5 yes
GO:0006661 phosphatidylinositol biosynthetic process 6.2500 6 yes
GO:2000544 regulation of endothelial cell chemotaxis to fibroblast growth factor 6.2500 6 yes
GO:2000546 positive regulation of endothelial cell chemotaxis to fibroblast growth factor 6.2500 7 yes
GO:0006812 cation transport 6.2500 5 yes
GO:0006816 calcium ion transport 6.2500 7 yes
GO:2001026 regulation of endothelial cell chemotaxis 6.2500 5 yes
GO:2001028 positive regulation of endothelial cell chemotaxis 6.2500 6 yes
GO:0008543 fibroblast growth factor receptor signaling pathway 6.2500 6 yes
GO:0008610 lipid biosynthetic process 6.2500 4 yes
GO:0008654 phospholipid biosynthetic process 6.2500 4 yes
GO:0009792 embryo development ending in birth or egg hatching 6.2500 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SDC2_HUMAN [view interactions] Low throughput no yes
SDC1_HUMAN [view interactions] Low throughput no no
FGFR2_HUMAN [view interactions] Low throughput no yes
RS19_HUMAN [view entry] [view interactions] Low throughput yes no
PTX3_HUMAN [view interactions] Low throughput no no
TSG6_HUMAN [view interactions] Low throughput no no
PGBM_HUMAN [view interactions] Low throughput no no
FGFR1_HUMAN [view interactions] Low throughput no yes
FGFR3_HUMAN [view interactions] Low throughput no yes
FGFP1_HUMAN [view interactions] Low throughput no no
KALM_HUMAN [view interactions] Low throughput no no
CASP1_HUMAN [view interactions] Low throughput no yes
PGS2_HUMAN [view interactions] Low throughput no no
RL6_HUMAN [view entry] [view interactions] Low throughput yes yes
GPC3_HUMAN [view interactions] Low throughput no no
FGRL1_HUMAN [view interactions] Low throughput no yes
KAPCA_HUMAN [view entry] [view interactions] Low throughput yes yes
RTN4R_HUMAN [view interactions] Low throughput no no
S100B_HUMAN [view entry] [view interactions] Low throughput yes yes
CSPG4_HUMAN [view interactions] Low throughput no yes
SDC4_HUMAN [view interactions] Low throughput no yes
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
CSK22_HUMAN [view entry] [view interactions] Low throughput yes no
CSK2B_HUMAN [view entry] [view interactions] Low throughput yes yes
VTNC_HUMAN [view interactions] Low throughput no no
SDC3_HUMAN [view interactions] Low throughput no yes
GPC4_HUMAN [view entry] [view interactions] Low throughput yes yes
TSP1_HUMAN [view interactions] Low throughput no no
SPRC_HUMAN [view interactions] Low throughput no yes
SNTG1_HUMAN [view interactions] Low throughput no no
ANM1_HUMAN [view interactions] Low throughput no yes
GSLG1_HUMAN [view entry] [view interactions] Low throughput yes yes
NRP1_HUMAN [view entry] [view interactions] Low throughput yes yes
CRYAB_HUMAN [view entry] [view interactions] Low throughput yes no
NR4A1_HUMAN [view interactions] High throughput no yes
CBP_HUMAN [view interactions] High throughput no yes
H33_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
TAXB1_HUMAN [view interactions] High throughput no yes
TEFF1_HUMAN [view interactions] High throughput no no
PDPK1_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR4_HUMAN [view interactions] High throughput no no
TBG1_HUMAN [view entry] [view interactions] High throughput yes yes
IF16_HUMAN [view interactions] High throughput no no
COMT_HUMAN [view entry] [view interactions] High throughput yes yes
CD44_HUMAN [view interactions] High throughput no yes
TES_HUMAN [view interactions] High throughput no yes
RAGE_HUMAN [view entry] [view interactions] High throughput yes no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
IL7RA_HUMAN [view interactions] High throughput no no
FGF17_HUMAN [view interactions] Computational no no
LIF_HUMAN [view interactions] Computational no yes
NEST_HUMAN [view interactions] Computational no no
NANOG_HUMAN [view interactions] Computational no no
COLI_HUMAN [view interactions] Computational no no
PDGFA_HUMAN [view interactions] Computational no yes
AGRIN_HUMAN [view entry] [view interactions] Computational yes yes
MMP2_HUMAN [view interactions] Computational no no
INS_HUMAN [view interactions] Computational no no
PROM1_HUMAN [view interactions] Computational no no
JAM1_HUMAN [view interactions] Computational no yes
IL6_HUMAN [view interactions] Computational no no
SAA1_HUMAN [view interactions] Computational no no