NMDE1_HUMAN
Evidence for PS localization
Functions
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed, PubMed, PubMed, PubMed). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have lower sensitivity to glutamate and faster deactivation kinetics than channels formed by GRIN1 and GRIN2B (PubMed, PubMed). Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NMDE1_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 35.1351 | 4 | yes |
| GO:0046872 | metal ion binding | 31.0811 | 5 | yes |
| GO:0043168 | anion binding | 31.0811 | 4 | no |
| GO:0000166 | nucleotide binding | 24.3243 | 4 | no |
| GO:0017076 | purine nucleotide binding | 24.3243 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 24.3243 | 6 | no |
| GO:0022890 | inorganic cation transmembrane transporter activity | 21.6216 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 21.6216 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 21.6216 | 5 | no |
| GO:0005216 | monoatomic ion channel activity | 20.2703 | 4 | yes |
| GO:0015267 | channel activity | 20.2703 | 4 | yes |
| GO:0005524 | ATP binding | 20.2703 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 20.2703 | 4 | no |
| GO:0019900 | kinase binding | 20.2703 | 4 | no |
| GO:0008066 | glutamate receptor activity | 17.5676 | 4 | yes |
| GO:0008324 | monoatomic cation transmembrane transporter activity | 17.5676 | 4 | yes |
| GO:0046873 | metal ion transmembrane transporter activity | 17.5676 | 5 | yes |
| GO:0046943 | carboxylic acid transmembrane transporter activity | 17.5676 | 4 | yes |
| GO:0004970 | glutamate-gated receptor activity | 16.2162 | 4 | yes |
| GO:0005230 | extracellular ligand-gated monoatomic ion channel activity | 16.2162 | 6 | yes |
| GO:0015276 | ligand-gated monoatomic ion channel activity | 16.2162 | 5 | yes |
| GO:0022824 | transmitter-gated monoatomic ion channel activity | 16.2162 | 5 | yes |
| GO:0022834 | ligand-gated channel activity | 16.2162 | 6 | yes |
| GO:0022835 | transmitter-gated channel activity | 16.2162 | 4 | yes |
| GO:0022836 | gated channel activity | 16.2162 | 5 | yes |
| GO:0098960 | postsynaptic neurotransmitter receptor activity | 16.2162 | 4 | yes |
| GO:0005261 | monoatomic cation channel activity | 13.5135 | 5 | yes |
| GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | 13.5135 | 5 | yes |
| GO:1904315 | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 13.5135 | 6 | yes |
| GO:0015085 | calcium ion transmembrane transporter activity | 12.1622 | 6 | yes |
| GO:0005262 | calcium channel activity | 10.8108 | 6 | yes |
| GO:0046914 | transition metal ion binding | 10.8108 | 6 | yes |
| GO:0004972 | NMDA glutamate receptor activity | 9.4595 | 5 | yes |
| GO:0005244 | voltage-gated monoatomic ion channel activity | 9.4595 | 5 | yes |
| GO:0022832 | voltage-gated channel activity | 9.4595 | 6 | yes |
| GO:0008270 | zinc ion binding | 8.1081 | 7 | yes |
| GO:0099094 | ligand-gated monoatomic cation channel activity | 8.1081 | 6 | yes |
| GO:0022849 | glutamate-gated calcium ion channel activity | 6.7568 | 5 | yes |
| GO:0099604 | ligand-gated calcium channel activity | 6.7568 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NMDE1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 74.3243 | 4 | yes |
| GO:0010646 | regulation of cell communication | 70.2703 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 59.4595 | 4 | no |
| GO:0009966 | regulation of signal transduction | 55.4054 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 54.0541 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 48.6486 | 4 | no |
| GO:0008104 | protein localization | 47.2973 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 45.9459 | 4 | yes |
| GO:0051049 | regulation of transport | 45.9459 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 44.5946 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 43.2432 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 40.5405 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.5405 | 5 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 40.5405 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 40.5405 | 4 | yes |
| GO:0022607 | cellular component assembly | 40.5405 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 37.8378 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 36.4865 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 35.1351 | 6 | yes |
| GO:0009889 | regulation of biosynthetic process | 33.7838 | 4 | no |
| GO:0010468 | regulation of gene expression | 32.4324 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 32.4324 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 32.4324 | 5 | no |
| GO:0099536 | synaptic signaling | 31.0811 | 4 | yes |
| GO:0099537 | trans-synaptic signaling | 31.0811 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 31.0811 | 5 | no |
| GO:0006996 | organelle organization | 31.0811 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 31.0811 | 6 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 31.0811 | 5 | no |
| GO:0031399 | regulation of protein modification process | 31.0811 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 31.0811 | 5 | no |
| GO:0007268 | chemical synaptic transmission | 29.7297 | 7 | yes |
| GO:0009892 | negative regulation of metabolic process | 29.7297 | 4 | yes |
| GO:0043269 | regulation of monoatomic ion transport | 29.7297 | 5 | yes |
| GO:0098916 | anterograde trans-synaptic signaling | 29.7297 | 6 | yes |
| GO:0051130 | positive regulation of cellular component organization | 29.7297 | 5 | no |
| GO:0036211 | protein modification process | 29.7297 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 29.7297 | 7 | no |
| GO:0043412 | macromolecule modification | 29.7297 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 29.7297 | 5 | no |
| GO:0023057 | negative regulation of signaling | 29.7297 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.3784 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 28.3784 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 28.3784 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 28.3784 | 7 | no |
| GO:0048585 | negative regulation of response to stimulus | 28.3784 | 4 | no |
| GO:0034762 | regulation of transmembrane transport | 27.0270 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 27.0270 | 5 | no |
| GO:0010243 | response to organonitrogen compound | 25.6757 | 4 | yes |
| GO:0050890 | cognition | 25.6757 | 4 | yes |
| GO:0044057 | regulation of system process | 24.3243 | 4 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 24.3243 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 24.3243 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 24.3243 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 24.3243 | 6 | no |
| GO:0030030 | cell projection organization | 24.3243 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 24.3243 | 7 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 24.3243 | 7 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 24.3243 | 5 | no |
| GO:0051050 | positive regulation of transport | 24.3243 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 24.3243 | 4 | no |
| GO:0071702 | organic substance transport | 24.3243 | 4 | no |
| GO:0071705 | nitrogen compound transport | 24.3243 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 22.9730 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 22.9730 | 6 | yes |
| GO:0072657 | protein localization to membrane | 22.9730 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 22.9730 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 22.9730 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 22.9730 | 5 | no |
| GO:0060341 | regulation of cellular localization | 22.9730 | 4 | no |
| GO:0034330 | cell junction organization | 22.9730 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.9730 | 5 | no |
| GO:0015031 | protein transport | 22.9730 | 4 | no |
| GO:0009894 | regulation of catabolic process | 21.6216 | 4 | yes |
| GO:0034765 | regulation of monoatomic ion transmembrane transport | 21.6216 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 21.6216 | 4 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 21.6216 | 8 | no |
| GO:0042327 | positive regulation of phosphorylation | 21.6216 | 8 | no |
| GO:0045595 | regulation of cell differentiation | 21.6216 | 4 | no |
| GO:0007215 | glutamate receptor signaling pathway | 20.2703 | 4 | yes |
| GO:0050806 | positive regulation of synaptic transmission | 20.2703 | 5 | yes |
| GO:1904062 | regulation of monoatomic cation transmembrane transport | 20.2703 | 6 | yes |
| GO:0033043 | regulation of organelle organization | 20.2703 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 20.2703 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 20.2703 | 7 | no |
| GO:0051252 | regulation of RNA metabolic process | 20.2703 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.2703 | 6 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 20.2703 | 4 | no |
| GO:0010959 | regulation of metal ion transport | 20.2703 | 6 | no |
| GO:0043933 | protein-containing complex organization | 20.2703 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 20.2703 | 5 | no |
| GO:0006811 | monoatomic ion transport | 18.9189 | 4 | yes |
| GO:0006812 | monoatomic cation transport | 17.5676 | 5 | yes |
| GO:0007612 | learning | 17.5676 | 4 | yes |
| GO:0030001 | metal ion transport | 17.5676 | 6 | yes |
| GO:0048168 | regulation of neuronal synaptic plasticity | 17.5676 | 4 | yes |
| GO:0051966 | regulation of synaptic transmission, glutamatergic | 17.5676 | 6 | yes |
| GO:0030162 | regulation of proteolysis | 16.2162 | 6 | yes |
| GO:0031644 | regulation of nervous system process | 16.2162 | 5 | yes |
| GO:0051336 | regulation of hydrolase activity | 16.2162 | 4 | yes |
| GO:0098815 | modulation of excitatory postsynaptic potential | 16.2162 | 4 | yes |
| GO:0006816 | calcium ion transport | 14.8649 | 7 | yes |
| GO:0035249 | synaptic transmission, glutamatergic | 14.8649 | 8 | yes |
| GO:0042176 | regulation of protein catabolic process | 14.8649 | 5 | yes |
| GO:0009895 | negative regulation of catabolic process | 13.5135 | 5 | yes |
| GO:0035235 | ionotropic glutamate receptor signaling pathway | 13.5135 | 4 | yes |
| GO:0043065 | positive regulation of apoptotic process | 13.5135 | 6 | yes |
| GO:0043068 | positive regulation of programmed cell death | 13.5135 | 5 | yes |
| GO:1902414 | protein localization to cell junction | 13.5135 | 5 | yes |
| GO:1990778 | protein localization to cell periphery | 13.5135 | 5 | yes |
| GO:2000463 | positive regulation of excitatory postsynaptic potential | 13.5135 | 5 | yes |
| GO:0007613 | memory | 12.1622 | 4 | yes |
| GO:0009057 | macromolecule catabolic process | 12.1622 | 4 | yes |
| GO:0009416 | response to light stimulus | 12.1622 | 4 | yes |
| GO:0035418 | protein localization to synapse | 12.1622 | 6 | yes |
| GO:0045862 | positive regulation of proteolysis | 12.1622 | 7 | yes |
| GO:0051968 | positive regulation of synaptic transmission, glutamatergic | 12.1622 | 6 | yes |
| GO:0097305 | response to alcohol | 12.1622 | 4 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 12.1622 | 4 | yes |
| GO:0006508 | proteolysis | 10.8108 | 4 | yes |
| GO:0008306 | associative learning | 10.8108 | 5 | yes |
| GO:0052547 | regulation of peptidase activity | 10.8108 | 5 | yes |
| GO:0060078 | regulation of postsynaptic membrane potential | 10.8108 | 4 | yes |
| GO:0098655 | monoatomic cation transmembrane transport | 10.8108 | 4 | yes |
| GO:0098662 | inorganic cation transmembrane transport | 10.8108 | 4 | yes |
| GO:0007420 | brain development | 9.4595 | 4 | yes |
| GO:0008542 | visual learning | 9.4595 | 4 | yes |
| GO:0030163 | protein catabolic process | 9.4595 | 4 | yes |
| GO:0045471 | response to ethanol | 9.4595 | 5 | yes |
| GO:0052548 | regulation of endopeptidase activity | 9.4595 | 6 | yes |
| GO:0060079 | excitatory postsynaptic potential | 9.4595 | 5 | yes |
| GO:0060291 | long-term synaptic potentiation | 9.4595 | 4 | yes |
| GO:0062237 | protein localization to postsynapse | 9.4595 | 7 | yes |
| GO:1903539 | protein localization to postsynaptic membrane | 9.4595 | 5 | yes |
| GO:2000116 | regulation of cysteine-type endopeptidase activity | 9.4595 | 7 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 8.1081 | 5 | yes |
| GO:0014075 | response to amine | 6.7568 | 5 | yes |
| GO:0042177 | negative regulation of protein catabolic process | 6.7568 | 6 | yes |
| GO:0050905 | neuromuscular process | 6.7568 | 4 | yes |
| GO:0070588 | calcium ion transmembrane transport | 6.7568 | 5 | yes |
| GO:0097553 | calcium ion transmembrane import into cytosol | 6.7568 | 6 | yes |
| GO:0098976 | excitatory chemical synaptic transmission | 6.7568 | 8 | yes |
| GO:0001975 | response to amphetamine | 5.4054 | 6 | yes |
| GO:0006576 | biogenic amine metabolic process | 5.4054 | 5 | yes |
| GO:0006584 | catecholamine metabolic process | 5.4054 | 6 | yes |
| GO:0007600 | sensory perception | 5.4054 | 4 | yes |
| GO:0009308 | amine metabolic process | 5.4054 | 4 | yes |
| GO:0009712 | catechol-containing compound metabolic process | 5.4054 | 5 | yes |
| GO:0010950 | positive regulation of endopeptidase activity | 5.4054 | 7 | yes |
| GO:0010952 | positive regulation of peptidase activity | 5.4054 | 6 | yes |
| GO:0018958 | phenol-containing compound metabolic process | 5.4054 | 4 | yes |
| GO:0042417 | dopamine metabolic process | 5.4054 | 7 | yes |
| GO:2001056 | positive regulation of cysteine-type endopeptidase activity | 5.4054 | 8 | yes |
| GO:0016485 | protein processing | 4.0541 | 5 | yes |
| GO:0022008 | neurogenesis | 4.0541 | 4 | yes |
| GO:0051604 | protein maturation | 4.0541 | 4 | yes |
| GO:0019233 | sensory perception of pain | 2.7027 | 5 | yes |
| GO:0031638 | zymogen activation | 2.7027 | 6 | yes |
| GO:0042430 | indole-containing compound metabolic process | 2.7027 | 4 | yes |
| GO:0097202 | activation of cysteine-type endopeptidase activity | 2.7027 | 7 | yes |
| GO:1901160 | primary amino compound metabolic process | 2.7027 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DLG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAGI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| INADL_HUMAN | [view interactions] | Low throughput | no | no |
| PTN4_HUMAN | [view interactions] | Low throughput | no | no |
| NETO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| IL16_HUMAN | [view interactions] | Low throughput | no | no |
| LRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NOS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| APC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRID2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLGP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CHIN_HUMAN | [view interactions] | Low throughput | no | no |
| NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AP1M1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| FAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMD3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DRD1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EPS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDE3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTN5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PDE10_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| APLP1_HUMAN | [view interactions] | Low throughput | no | yes |
| APLP2_HUMAN | [view interactions] | Low throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P2RY1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RP3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMD3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRM5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCC2D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSK22_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSK2B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTND2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| IQEC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRIK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IQEC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PP2BC_HUMAN | [view interactions] | Low throughput | no | yes |
| AT2B2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZNT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RIMS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF3B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KIFA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CBAR1_HUMAN | [view interactions] | High throughput | no | no |
| HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EAA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TTC28_HUMAN | [view interactions] | High throughput | no | no |
| PDE3B_HUMAN | [view interactions] | High throughput | no | no |
| 2A5D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2A5E_HUMAN | [view interactions] | High throughput | no | yes |
| 2A5B_HUMAN | [view interactions] | High throughput | no | yes |
| HIG2A_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A3_HUMAN | [view interactions] | High throughput | no | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABCD4_HUMAN | [view interactions] | High throughput | no | yes |
| AT5G1_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LY6D_HUMAN | [view interactions] | High throughput | no | no |
| ST7_HUMAN | [view interactions] | High throughput | no | yes |
| NSMA_HUMAN | [view interactions] | High throughput | no | yes |
| UFSP2_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| LRP6_HUMAN | [view interactions] | High throughput | no | yes |
| CISD2_HUMAN | [view interactions] | High throughput | no | yes |
| PIGA_HUMAN | [view interactions] | High throughput | no | yes |
| DJC18_HUMAN | [view interactions] | High throughput | no | yes |
| ABCB9_HUMAN | [view interactions] | High throughput | no | yes |
| NXNL2_HUMAN | [view interactions] | High throughput | no | no |
| METL9_HUMAN | [view interactions] | High throughput | no | yes |
| LMF2_HUMAN | [view interactions] | High throughput | no | yes |
| UBP33_HUMAN | [view interactions] | High throughput | no | yes |
| TAP2_HUMAN | [view interactions] | High throughput | no | no |
| 2AAB_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S27A3_HUMAN | [view interactions] | High throughput | no | no |
| MIB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEUL4_HUMAN | [view interactions] | High throughput | no | yes |
| CNTP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |