NUMB_HUMAN
Evidence for PS localization
Functions
Regulates clathrin-mediated receptor endocytosis (PubMed). Plays a role in the process of neurogenesis . Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate . Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity . May also mediate local repair of brain ventricular wall damage . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002841 | DEG_MDM2_SWIB_1 | DEG | 616 | 623 | - |
| ELMI001132 | LIG_EH_1 | LIG | 636 | 640 | - |
| ELMI002841 | DEG_MDM2_SWIB_1 | DEG | 616 | 623 | - |
| ELMI001132 | LIG_EH_1 | LIG | 636 | 640 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NUMB_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 43.2432 | 4 | no |
| GO:0000166 | nucleotide binding | 40.5405 | 4 | no |
| GO:0017076 | purine nucleotide binding | 40.5405 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 40.5405 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 39.6396 | 4 | no |
| GO:0019900 | kinase binding | 27.9279 | 4 | no |
| GO:0019901 | protein kinase binding | 27.9279 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 25.2252 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.2252 | 5 | no |
| GO:0005524 | ATP binding | 24.3243 | 5 | no |
| GO:0043169 | cation binding | 20.7207 | 4 | no |
| GO:0046872 | metal ion binding | 20.7207 | 5 | no |
| GO:0045296 | cadherin binding | 19.8198 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NUMB_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 72.9730 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 60.3604 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 60.3604 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 58.5586 | 4 | no |
| GO:0010646 | regulation of cell communication | 56.7568 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 55.8559 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 52.2523 | 4 | no |
| GO:0009966 | regulation of signal transduction | 50.4505 | 4 | no |
| GO:0008104 | protein localization | 49.5495 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 46.8468 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 46.8468 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 45.9459 | 5 | no |
| GO:0051049 | regulation of transport | 45.0450 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 44.1441 | 4 | no |
| GO:0010468 | regulation of gene expression | 43.2432 | 6 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 43.2432 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 42.3423 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 42.3423 | 4 | no |
| GO:0023056 | positive regulation of signaling | 40.5405 | 4 | no |
| GO:0022607 | cellular component assembly | 39.6396 | 4 | no |
| GO:0060341 | regulation of cellular localization | 39.6396 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 39.6396 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 38.7387 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 37.8378 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 36.9369 | 4 | no |
| GO:0032880 | regulation of protein localization | 36.9369 | 5 | yes |
| GO:0071702 | organic substance transport | 36.9369 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 36.9369 | 5 | no |
| GO:0006996 | organelle organization | 36.0360 | 4 | no |
| GO:0071705 | nitrogen compound transport | 35.1351 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 34.2342 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 33.3333 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.4324 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 32.4324 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 32.4324 | 4 | no |
| GO:0015031 | protein transport | 30.6306 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 30.6306 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 29.7297 | 6 | no |
| GO:0031399 | regulation of protein modification process | 29.7297 | 6 | no |
| GO:2000145 | regulation of cell motility | 29.7297 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 29.7297 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 29.7297 | 6 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.8288 | 6 | no |
| GO:0030030 | cell projection organization | 28.8288 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 28.8288 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 28.8288 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 28.8288 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.8288 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 28.8288 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 28.8288 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 28.8288 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 27.9279 | 6 | no |
| GO:0030334 | regulation of cell migration | 27.9279 | 5 | yes |
| GO:2000026 | regulation of multicellular organismal development | 27.9279 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 27.0270 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 27.0270 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 27.0270 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 27.0270 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 27.0270 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 27.0270 | 5 | no |
| GO:0023057 | negative regulation of signaling | 27.0270 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.1261 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 25.2252 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 25.2252 | 7 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 25.2252 | 4 | no |
| GO:0098657 | import into cell | 25.2252 | 4 | no |
| GO:0032101 | regulation of response to external stimulus | 25.2252 | 4 | no |
| GO:0141124 | intracellular signaling cassette | 24.3243 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.3243 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 24.3243 | 6 | no |
| GO:0002684 | positive regulation of immune system process | 24.3243 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 24.3243 | 5 | no |
| GO:0036211 | protein modification process | 24.3243 | 4 | no |
| GO:0043412 | macromolecule modification | 24.3243 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 23.4234 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 23.4234 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 23.4234 | 4 | no |
| GO:0051050 | positive regulation of transport | 23.4234 | 4 | no |
| GO:0060284 | regulation of cell development | 23.4234 | 5 | yes |
| GO:0043408 | regulation of MAPK cascade | 23.4234 | 6 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 23.4234 | 5 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 22.5225 | 4 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 22.5225 | 6 | no |
| GO:0030155 | regulation of cell adhesion | 22.5225 | 4 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.5225 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 22.5225 | 7 | no |
| GO:0030335 | positive regulation of cell migration | 22.5225 | 6 | yes |
| GO:0040017 | positive regulation of locomotion | 22.5225 | 4 | yes |
| GO:2000147 | positive regulation of cell motility | 22.5225 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 22.5225 | 5 | no |
| GO:0010243 | response to organonitrogen compound | 22.5225 | 4 | no |
| GO:0080134 | regulation of response to stress | 22.5225 | 4 | no |
| GO:0050776 | regulation of immune response | 21.6216 | 4 | no |
| GO:0043066 | negative regulation of apoptotic process | 21.6216 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 21.6216 | 5 | no |
| GO:0051726 | regulation of cell cycle | 21.6216 | 4 | no |
| GO:0007010 | cytoskeleton organization | 20.7207 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 20.7207 | 5 | no |
| GO:0006886 | intracellular protein transport | 20.7207 | 4 | no |
| GO:0045597 | positive regulation of cell differentiation | 20.7207 | 5 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 20.7207 | 4 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 20.7207 | 5 | no |
| GO:0010975 | regulation of neuron projection development | 20.7207 | 7 | no |
| GO:0016310 | phosphorylation | 20.7207 | 5 | no |
| GO:0034330 | cell junction organization | 19.8198 | 4 | yes |
| GO:0050767 | regulation of neurogenesis | 16.2162 | 6 | yes |
| GO:0051960 | regulation of nervous system development | 16.2162 | 5 | yes |
| GO:0010720 | positive regulation of cell development | 15.3153 | 6 | yes |
| GO:1905475 | regulation of protein localization to membrane | 15.3153 | 6 | yes |
| GO:0030100 | regulation of endocytosis | 12.6126 | 5 | yes |
| GO:0045216 | cell-cell junction organization | 12.6126 | 5 | yes |
| GO:1904375 | regulation of protein localization to cell periphery | 12.6126 | 6 | yes |
| GO:0048812 | neuron projection morphogenesis | 11.7117 | 5 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 11.7117 | 4 | yes |
| GO:0050769 | positive regulation of neurogenesis | 10.8108 | 6 | yes |
| GO:0051962 | positive regulation of nervous system development | 10.8108 | 5 | yes |
| GO:1903076 | regulation of protein localization to plasma membrane | 10.8108 | 7 | yes |
| GO:1903828 | negative regulation of protein localization | 9.9099 | 5 | yes |
| GO:0007409 | axonogenesis | 9.0090 | 6 | yes |
| GO:0048259 | regulation of receptor-mediated endocytosis | 8.1081 | 6 | yes |
| GO:0034332 | adherens junction organization | 7.2072 | 6 | yes |
| GO:0002090 | regulation of receptor internalization | 4.5045 | 7 | yes |
| GO:1903077 | negative regulation of protein localization to plasma membrane | 3.6036 | 7 | yes |
| GO:1904376 | negative regulation of protein localization to cell periphery | 3.6036 | 6 | yes |
| GO:1905476 | negative regulation of protein localization to membrane | 3.6036 | 6 | yes |
| GO:0021849 | neuroblast division in subventricular zone | 2.7027 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DPTOR_HUMAN | [view interactions] | Low throughput | no | no |
| RPTOR_HUMAN | [view interactions] | Low throughput | no | yes |
| MTOR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LST8_HUMAN | [view interactions] | Low throughput | no | yes |
| IGSF5_HUMAN | [view interactions] | Low throughput | no | no |
| KPCE_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EPS15_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LNX1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NUMB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AP2A1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| REPS1_HUMAN | [view interactions] | Low throughput | no | yes |
| RBP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P53_HUMAN | [view interactions] | Low throughput | no | no |
| MDM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DPYL2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FBW1A_HUMAN | [view interactions] | Low throughput | no | yes |
| SIAH1_HUMAN | [view interactions] | Low throughput | no | yes |
| TFR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LNX2_HUMAN | [view interactions] | Low throughput | no | yes |
| L1CAM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITCH_HUMAN | [view interactions] | Low throughput | no | yes |
| GLI1_HUMAN | [view interactions] | Low throughput | no | no |
| NOTC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| JUN_HUMAN | [view interactions] | Low throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CADH2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CTNA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHOT1_HUMAN | [view interactions] | Low throughput | no | no |
| TRPV6_HUMAN | [view interactions] | Low throughput | no | no |
| VIME_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CDC42_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NOG2_HUMAN | [view interactions] | High throughput | no | yes |
| EAA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKD2_HUMAN | [view interactions] | High throughput | no | yes |
| APC15_HUMAN | [view interactions] | High throughput | no | yes |
| SPCS1_HUMAN | [view interactions] | High throughput | no | yes |
| PEN2_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S10A2_HUMAN | [view interactions] | High throughput | no | no |
| BEX1_HUMAN | [view interactions] | High throughput | no | yes |
| SPRY4_HUMAN | [view interactions] | High throughput | no | yes |
| KLH21_HUMAN | [view interactions] | High throughput | no | no |
| ZCH10_HUMAN | [view interactions] | High throughput | no | yes |
| CT197_HUMAN | [view interactions] | High throughput | no | no |
| NUMBL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAAT_HUMAN | [view interactions] | High throughput | no | yes |
| SPSB3_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| AAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NECP2_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DCA15_HUMAN | [view interactions] | High throughput | no | no |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| SMAP2_HUMAN | [view interactions] | High throughput | no | yes |
| RET_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG12_HUMAN | [view interactions] | High throughput | no | yes |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
| DTX2_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| ESYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| SSR3_HUMAN | [view interactions] | High throughput | no | yes |
| WWTR1_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
| BMP2K_HUMAN | [view interactions] | High throughput | no | yes |
| BCLF1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EP15R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITB5_HUMAN | [view interactions] | High throughput | no | yes |
| ITB7_HUMAN | [view interactions] | High throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHB1_HUMAN | [view interactions] | High throughput | no | no |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR2_HUMAN | [view interactions] | High throughput | no | yes |
| FLT3_HUMAN | [view interactions] | High throughput | no | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KIT_HUMAN | [view interactions] | High throughput | no | no |
| MERTK_HUMAN | [view interactions] | High throughput | no | yes |
| PGFRA_HUMAN | [view interactions] | High throughput | no | no |
| VGFR2_HUMAN | [view interactions] | High throughput | no | no |
| PTPRC_HUMAN | [view interactions] | High throughput | no | no |
| DOK1_HUMAN | [view interactions] | High throughput | no | yes |
| DOK2_HUMAN | [view interactions] | High throughput | no | no |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH2B3_HUMAN | [view interactions] | High throughput | no | yes |
| ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IRS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FRS3_HUMAN | [view interactions] | High throughput | no | no |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTDSL_HUMAN | [view interactions] | High throughput | no | no |
| ALK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA5_HUMAN | [view interactions] | High throughput | no | no |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROR1_HUMAN | [view interactions] | High throughput | no | no |
| ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OLIG1_HUMAN | [view interactions] | High throughput | no | no |
| JIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TERF2_HUMAN | [view interactions] | High throughput | no | yes |
| PALS1_HUMAN | [view interactions] | High throughput | no | no |
| EAF1_HUMAN | [view interactions] | High throughput | no | yes |
| PDZ1I_HUMAN | [view interactions] | High throughput | no | no |
| SPXN2_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGBP1_HUMAN | [view interactions] | High throughput | no | yes |
| RENR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTBD8_HUMAN | [view interactions] | High throughput | no | yes |
| GTSE1_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| OSGEP_HUMAN | [view interactions] | High throughput | no | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| KBTB7_HUMAN | [view interactions] | High throughput | no | yes |
| UN5CL_HUMAN | [view interactions] | High throughput | no | no |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| STALP_HUMAN | [view interactions] | High throughput | no | yes |
| COAA1_HUMAN | [view interactions] | High throughput | no | no |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |