Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ARVC_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Involved in protein-protein interactions at adherens junctions. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI003528 LIG_PDZ_Wminus1_1 LIG 960 962 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ARVC_HUMAN
GO:0045296 cadherin binding 41.1765 4 yes
GO:0019900 kinase binding 41.1765 4 no
GO:0019901 protein kinase binding 41.1765 5 no
GO:0046872 metal ion binding 23.5294 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in ARVC_HUMAN
GO:0048523 negative regulation of cellular process 76.4706 4 no
GO:0048522 positive regulation of cellular process 70.5882 4 no
GO:0010646 regulation of cell communication 64.7059 4 no
GO:0009966 regulation of signal transduction 52.9412 4 no
GO:0060255 regulation of macromolecule metabolic process 52.9412 4 no
GO:0010647 positive regulation of cell communication 47.0588 5 no
GO:0034330 cell junction organization 47.0588 4 yes
GO:0010468 regulation of gene expression 47.0588 5 no
GO:0031323 regulation of cellular metabolic process 47.0588 4 no
GO:0051171 regulation of nitrogen compound metabolic process 47.0588 4 no
GO:0080090 regulation of primary metabolic process 47.0588 4 no
GO:0008104 protein localization 47.0588 4 no
GO:0009967 positive regulation of signal transduction 41.1765 5 no
GO:0023056 positive regulation of signaling 41.1765 4 no
GO:0048584 positive regulation of response to stimulus 41.1765 4 no
GO:0022607 cellular component assembly 41.1765 4 yes
GO:0051128 regulation of cellular component organization 41.1765 4 no
GO:0009893 positive regulation of metabolic process 41.1765 4 no
GO:0010604 positive regulation of macromolecule metabolic process 41.1765 5 no
GO:0051049 regulation of transport 41.1765 4 no
GO:1902531 regulation of intracellular signal transduction 35.2941 5 no
GO:1902533 positive regulation of intracellular signal transduction 35.2941 6 no
GO:0034329 cell junction assembly 35.2941 5 yes
GO:0045216 cell-cell junction organization 35.2941 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 35.2941 5 no
GO:0051252 regulation of RNA metabolic process 35.2941 5 no
GO:0022603 regulation of anatomical structure morphogenesis 35.2941 4 no
GO:0031325 positive regulation of cellular metabolic process 35.2941 5 no
GO:0032880 regulation of protein localization 35.2941 5 no
GO:0050804 modulation of chemical synaptic transmission 35.2941 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 35.2941 5 no
GO:0060341 regulation of cellular localization 35.2941 4 no
GO:0099177 regulation of trans-synaptic signaling 35.2941 4 no
GO:2001141 regulation of RNA biosynthetic process 29.4118 6 no
GO:0009892 negative regulation of metabolic process 29.4118 4 no
GO:0010605 negative regulation of macromolecule metabolic process 29.4118 5 no
GO:0031344 regulation of cell projection organization 29.4118 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 29.4118 6 no
GO:0048585 negative regulation of response to stimulus 29.4118 4 no
GO:0030334 regulation of cell migration 29.4118 5 no
GO:0033043 regulation of organelle organization 29.4118 5 no
GO:2000145 regulation of cell motility 29.4118 4 no
GO:0006355 regulation of DNA-templated transcription 29.4118 6 no
GO:0009889 regulation of biosynthetic process 29.4118 4 no
GO:0010556 regulation of macromolecule biosynthetic process 29.4118 5 no
GO:0031326 regulation of cellular biosynthetic process 29.4118 5 no
GO:0050808 synapse organization 29.4118 5 no
GO:0051050 positive regulation of transport 29.4118 4 no
GO:0051246 regulation of protein metabolic process 29.4118 5 no
GO:1903506 regulation of nucleic acid-templated transcription 29.4118 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 23.5294 8 no
GO:0010975 regulation of neuron projection development 23.5294 7 no
GO:0031399 regulation of protein modification process 23.5294 6 no
GO:0031401 positive regulation of protein modification process 23.5294 7 no
GO:0051247 positive regulation of protein metabolic process 23.5294 6 no
GO:0042127 regulation of cell population proliferation 23.5294 4 no
GO:0042692 muscle cell differentiation 23.5294 4 no
GO:0043408 regulation of MAPK cascade 23.5294 6 no
GO:0043410 positive regulation of MAPK cascade 23.5294 7 no
GO:0010628 positive regulation of gene expression 23.5294 6 no
GO:0045595 regulation of cell differentiation 23.5294 4 no
GO:0007043 cell-cell junction assembly 23.5294 6 yes
GO:0009968 negative regulation of signal transduction 23.5294 5 no
GO:0010648 negative regulation of cell communication 23.5294 5 no
GO:0023057 negative regulation of signaling 23.5294 4 no
GO:0006996 organelle organization 23.5294 4 no
GO:0010941 regulation of cell death 23.5294 4 no
GO:0016192 vesicle-mediated transport 23.5294 4 no
GO:0042981 regulation of apoptotic process 23.5294 6 no
GO:0043067 regulation of programmed cell death 23.5294 5 no
GO:0051240 positive regulation of multicellular organismal process 23.5294 4 no
GO:1901701 cellular response to oxygen-containing compound 23.5294 4 no
GO:2000026 regulation of multicellular organismal development 23.5294 4 no
GO:0009891 positive regulation of biosynthetic process 23.5294 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 23.5294 6 no
GO:0030030 cell projection organization 23.5294 4 no
GO:0031328 positive regulation of cellular biosynthetic process 23.5294 6 no
GO:0045893 positive regulation of DNA-templated transcription 23.5294 7 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 23.5294 6 no
GO:0051223 regulation of protein transport 23.5294 5 no
GO:0051254 positive regulation of RNA metabolic process 23.5294 6 no
GO:0070201 regulation of establishment of protein localization 23.5294 6 no
GO:0071310 cellular response to organic substance 23.5294 4 no
GO:0072657 protein localization to membrane 23.5294 4 no
GO:1902680 positive regulation of RNA biosynthetic process 23.5294 7 no
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 17.6471 4 yes
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 11.7647 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ERBIN_HUMAN [view entry] [view interactions] Low throughput yes yes
CAD15_HUMAN [view interactions] Low throughput no no
CADH1_HUMAN [view entry] [view interactions] Low throughput yes no
CADH2_HUMAN [view entry] [view interactions] Low throughput yes no
ARGL1_HUMAN [view interactions] High throughput no yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP1_HUMAN [view entry] [view interactions] High throughput yes no
CTDSL_HUMAN [view interactions] High throughput no no
LNX1_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
CADH8_HUMAN [view interactions] High throughput no no
CADH5_HUMAN [view interactions] High throughput no yes
CTNA3_HUMAN [view interactions] High throughput no no
NK1R_HUMAN [view interactions] High throughput no no
SDC1_HUMAN [view interactions] High throughput no no
CP2S1_HUMAN [view interactions] High throughput no no
CXB7_HUMAN [view interactions] High throughput no no
S1PR2_HUMAN [view interactions] High throughput no no
CBPA5_HUMAN [view interactions] High throughput no no
P4HA2_HUMAN [view interactions] High throughput no no
PROZ_HUMAN [view interactions] High throughput no no
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
ESR2_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
ACK1_HUMAN [view interactions] High throughput no yes
AAKG3_HUMAN [view interactions] High throughput no no
ANLN_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
INS_HUMAN [view interactions] High throughput no no
CYTM1_HUMAN [view interactions] High throughput no no
TX1B3_HUMAN [view interactions] High throughput no no
EFNA4_HUMAN [view interactions] High throughput no no
CERS2_HUMAN [view interactions] High throughput no no
SEM4C_HUMAN [view entry] [view interactions] High throughput yes no
CAD12_HUMAN [view interactions] High throughput no no
SCML1_HUMAN [view interactions] High throughput no no
CC85A_HUMAN [view interactions] High throughput no yes
S10A2_HUMAN [view interactions] High throughput no no
SLIRP_HUMAN [view interactions] High throughput no yes
PRSR2_HUMAN [view interactions] High throughput no yes
GPR45_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
CTND1_HUMAN [view entry] [view interactions] High throughput yes no
EZH2_HUMAN [view interactions] High throughput no no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
ANK3_HUMAN [view entry] [view interactions] High throughput yes yes
CK052_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
KAZRN_HUMAN [view interactions] Computational no yes
ZO2_HUMAN [view entry] [view interactions] Computational yes no