Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RPP29_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5-ends. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in RPP29_HUMAN
GO:0003723 RNA binding 46.1538 4 yes
GO:0043169 cation binding 23.0769 4 no
GO:0046872 metal ion binding 23.0769 5 no
GO:0019900 kinase binding 23.0769 4 no
GO:0004518 nuclease activity 15.3846 4 yes
GO:0004519 endonuclease activity 15.3846 5 yes
GO:0004521 RNA endonuclease activity 15.3846 5 yes
GO:0004526 ribonuclease P activity 15.3846 6 yes
GO:0004540 RNA nuclease activity 15.3846 4 yes
GO:0004549 tRNA-specific ribonuclease activity 15.3846 5 yes
GO:0016891 RNA endonuclease activity, producing 5-phosphomonoesters 15.3846 6 yes
GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5-phosphomonoesters 15.3846 6 yes
GO:0033204 ribonuclease P RNA binding 15.3846 5 yes
GO:0140101 catalytic activity, acting on a tRNA 15.3846 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RPP29_HUMAN
GO:0048522 positive regulation of cellular process 53.8462 4 no
GO:0051246 regulation of protein metabolic process 46.1538 5 no
GO:0060255 regulation of macromolecule metabolic process 46.1538 4 no
GO:0080090 regulation of primary metabolic process 46.1538 4 no
GO:0009966 regulation of signal transduction 46.1538 4 no
GO:0010646 regulation of cell communication 46.1538 4 no
GO:0031323 regulation of cellular metabolic process 46.1538 4 no
GO:0048523 negative regulation of cellular process 46.1538 4 no
GO:0051174 regulation of phosphorus metabolic process 38.4615 5 no
GO:0051252 regulation of RNA metabolic process 38.4615 5 no
GO:0051726 regulation of cell cycle 38.4615 4 no
GO:1901987 regulation of cell cycle phase transition 38.4615 6 no
GO:2001141 regulation of RNA biosynthetic process 38.4615 6 no
GO:0090304 nucleic acid metabolic process 38.4615 4 yes
GO:0042127 regulation of cell population proliferation 38.4615 4 no
GO:0001932 regulation of protein phosphorylation 38.4615 7 no
GO:0006355 regulation of DNA-templated transcription 38.4615 7 no
GO:0008104 protein localization 38.4615 4 no
GO:0009889 regulation of biosynthetic process 38.4615 4 no
GO:0009892 negative regulation of metabolic process 38.4615 4 no
GO:0010468 regulation of gene expression 38.4615 6 no
GO:0010556 regulation of macromolecule biosynthetic process 38.4615 5 no
GO:0010564 regulation of cell cycle process 38.4615 5 no
GO:0010605 negative regulation of macromolecule metabolic process 38.4615 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 38.4615 5 no
GO:0019220 regulation of phosphate metabolic process 38.4615 6 no
GO:0031324 negative regulation of cellular metabolic process 38.4615 5 no
GO:0031326 regulation of cellular biosynthetic process 38.4615 5 no
GO:0031399 regulation of protein modification process 38.4615 6 no
GO:0042325 regulation of phosphorylation 38.4615 7 no
GO:0051247 positive regulation of protein metabolic process 30.7692 6 no
GO:0051248 negative regulation of protein metabolic process 30.7692 6 no
GO:0060341 regulation of cellular localization 30.7692 4 no
GO:1903829 positive regulation of protein localization 30.7692 5 no
GO:0001558 regulation of cell growth 30.7692 4 no
GO:0051128 regulation of cellular component organization 30.7692 4 no
GO:1902531 regulation of intracellular signal transduction 30.7692 5 no
GO:0006396 RNA processing 30.7692 6 yes
GO:0016070 RNA metabolic process 30.7692 5 yes
GO:0008284 positive regulation of cell population proliferation 30.7692 5 no
GO:0006357 regulation of transcription by RNA polymerase II 30.7692 8 no
GO:0009890 negative regulation of biosynthetic process 30.7692 5 no
GO:0009893 positive regulation of metabolic process 30.7692 4 no
GO:0009894 regulation of catabolic process 30.7692 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 30.7692 6 no
GO:0010604 positive regulation of macromolecule metabolic process 30.7692 5 no
GO:0031325 positive regulation of cellular metabolic process 30.7692 5 no
GO:0031327 negative regulation of cellular biosynthetic process 30.7692 6 no
GO:0031401 positive regulation of protein modification process 30.7692 7 no
GO:0032880 regulation of protein localization 30.7692 5 no
GO:0042981 regulation of apoptotic process 30.7692 5 no
GO:0043066 negative regulation of apoptotic process 30.7692 6 no
GO:0043067 regulation of programmed cell death 30.7692 4 no
GO:0043069 negative regulation of programmed cell death 30.7692 5 no
GO:0051254 positive regulation of RNA metabolic process 23.0769 6 no
GO:0051336 regulation of hydrolase activity 23.0769 4 no
GO:0080134 regulation of response to stress 23.0769 4 no
GO:0090068 positive regulation of cell cycle process 23.0769 6 no
GO:1901989 positive regulation of cell cycle phase transition 23.0769 7 no
GO:1902680 positive regulation of RNA biosynthetic process 23.0769 7 no
GO:1902806 regulation of cell cycle G1/S phase transition 23.0769 7 no
GO:0001933 negative regulation of protein phosphorylation 23.0769 8 no
GO:0006417 regulation of translation 23.0769 6 no
GO:0006886 intracellular protein transport 23.0769 4 no
GO:0010563 negative regulation of phosphorus metabolic process 23.0769 6 no
GO:0010608 post-transcriptional regulation of gene expression 23.0769 7 no
GO:0015031 protein transport 23.0769 4 no
GO:0022607 cellular component assembly 23.0769 4 no
GO:0031400 negative regulation of protein modification process 23.0769 7 no
GO:0042326 negative regulation of phosphorylation 23.0769 8 no
GO:0043549 regulation of kinase activity 23.0769 5 no
GO:0043933 protein-containing complex organization 23.0769 4 no
GO:0044087 regulation of cellular component biogenesis 23.0769 4 no
GO:0045859 regulation of protein kinase activity 23.0769 6 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 23.0769 5 no
GO:0045936 negative regulation of phosphate metabolic process 23.0769 7 no
GO:0051052 regulation of DNA metabolic process 23.0769 5 no
GO:0051338 regulation of transferase activity 23.0769 4 no
GO:0071702 organic substance transport 23.0769 4 no
GO:0071705 nitrogen compound transport 23.0769 4 no
GO:0007346 regulation of mitotic cell cycle 23.0769 5 no
GO:1901990 regulation of mitotic cell cycle phase transition 23.0769 6 no
GO:0009059 macromolecule biosynthetic process 23.0769 4 no
GO:0001934 positive regulation of protein phosphorylation 23.0769 8 no
GO:0006996 organelle organization 23.0769 4 no
GO:0009891 positive regulation of biosynthetic process 23.0769 5 no
GO:0009895 negative regulation of catabolic process 23.0769 5 no
GO:0009968 negative regulation of signal transduction 23.0769 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 23.0769 6 no
GO:0010562 positive regulation of phosphorus metabolic process 23.0769 6 no
GO:0010628 positive regulation of gene expression 23.0769 7 no
GO:0010629 negative regulation of gene expression 23.0769 7 no
GO:0010648 negative regulation of cell communication 23.0769 5 no
GO:0023057 negative regulation of signaling 23.0769 4 no
GO:0031328 positive regulation of cellular biosynthetic process 23.0769 6 no
GO:0033365 protein localization to organelle 23.0769 5 no
GO:0036211 protein modification process 23.0769 4 no
GO:0042327 positive regulation of phosphorylation 23.0769 8 no
GO:0043085 positive regulation of catalytic activity 23.0769 4 no
GO:0043412 macromolecule modification 23.0769 4 no
GO:0045787 positive regulation of cell cycle 23.0769 5 no
GO:0045893 positive regulation of DNA-templated transcription 23.0769 8 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 23.0769 5 no
GO:0045937 positive regulation of phosphate metabolic process 23.0769 7 no
GO:0045944 positive regulation of transcription by RNA polymerase II 23.0769 9 no
GO:0048585 negative regulation of response to stimulus 23.0769 4 no
GO:0051091 positive regulation of DNA-binding transcription factor activity 23.0769 4 no
GO:0000966 RNA 5-end processing 15.3846 7 yes
GO:0001682 tRNA 5-leader removal 15.3846 8 yes
GO:0006364 rRNA processing 15.3846 6 yes
GO:0006399 tRNA metabolic process 15.3846 6 yes
GO:0008033 tRNA processing 15.3846 6 yes
GO:0016072 rRNA metabolic process 15.3846 6 yes
GO:0099116 tRNA 5-end processing 15.3846 7 yes
GO:0141188 nucleic acid catabolic process 15.3846 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
POP7_HUMAN [view interactions] Low throughput no yes
RPP14_HUMAN [view interactions] Low throughput no no
RPP38_HUMAN [view interactions] Low throughput no yes
RPP30_HUMAN [view interactions] Low throughput no yes
POP5_HUMAN [view interactions] Low throughput no no
POP1_HUMAN [view interactions] Low throughput no no
RPP25_HUMAN [view interactions] Low throughput no yes
RPP21_HUMAN [view interactions] Low throughput no no
NEPRO_HUMAN [view interactions] Low throughput no no
RPP40_HUMAN [view interactions] Low throughput no no
RL10_HUMAN [view entry] [view interactions] High throughput yes yes
PRP4_HUMAN [view interactions] High throughput no yes
PP2AA_HUMAN [view entry] [view interactions] High throughput yes yes
S10A4_HUMAN [view entry] [view interactions] High throughput yes no
TOIP2_HUMAN [view interactions] High throughput no no
VSIG4_HUMAN [view interactions] High throughput no no
I13R2_HUMAN [view interactions] High throughput no no
I20RA_HUMAN [view interactions] High throughput no no
PCD20_HUMAN [view interactions] High throughput no no
CADH5_HUMAN [view interactions] High throughput no yes
RBM4_HUMAN [view interactions] High throughput no yes
VTNC_HUMAN [view interactions] High throughput no no
RL18A_HUMAN [view entry] [view interactions] High throughput yes yes
NDK8_HUMAN [view interactions] High throughput no no
GLU2B_HUMAN [view interactions] High throughput no yes
DCAM_HUMAN [view interactions] High throughput no yes
CR021_HUMAN [view interactions] High throughput no no
RP25L_HUMAN [view interactions] High throughput no yes
OSTF1_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
RBM4B_HUMAN [view interactions] High throughput no yes
PR15A_HUMAN [view interactions] High throughput no yes
RPP29_HUMAN [view entry] [view interactions] High throughput yes yes
MYC_HUMAN [view interactions] High throughput no yes
ESR1_HUMAN [view interactions] High throughput no no
SOX4_HUMAN [view interactions] High throughput no yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
ZNG1A_HUMAN [view interactions] High throughput no yes
IF16_HUMAN [view interactions] High throughput no no
PCDA3_HUMAN [view interactions] High throughput no no
PCDGG_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
LARP7_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
KALM_HUMAN [view interactions] High throughput no no
HIBCH_HUMAN [view entry] [view interactions] High throughput yes yes
HFE_HUMAN [view interactions] High throughput no yes
CBX6_HUMAN [view interactions] High throughput no yes
FRIL_HUMAN [view interactions] High throughput no yes
NPM3_HUMAN [view interactions] High throughput no yes
RRP5_HUMAN [view interactions] High throughput no yes
TFR2_HUMAN [view interactions] High throughput no no
GP182_HUMAN [view interactions] High throughput no no
CHM2A_HUMAN [view interactions] High throughput no yes
RAMP3_HUMAN [view interactions] High throughput no no
TRAK1_HUMAN [view interactions] High throughput no yes
ZN467_HUMAN [view interactions] High throughput no no
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
TICN2_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
SNX27_HUMAN [view entry] [view interactions] High throughput yes no
DRG1_HUMAN [view interactions] High throughput no yes
LA_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
MOB3C_HUMAN [view interactions] High throughput no no
KAT6A_HUMAN [view interactions] High throughput no yes
UBP36_HUMAN [view interactions] High throughput no yes
AKT1_HUMAN [view entry] [view interactions] High throughput yes yes
RPA34_HUMAN [view interactions] High throughput no yes
PML_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes