RPP29_HUMAN
Evidence for PS localization
Functions
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5-ends. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in RPP29_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 53.3333 | 4 | yes |
| GO:0046872 | metal ion binding | 26.6667 | 4 | no |
| GO:0004518 | nuclease activity | 20.0000 | 4 | yes |
| GO:0004519 | endonuclease activity | 20.0000 | 5 | yes |
| GO:0004521 | endoribonuclease activity | 20.0000 | 5 | yes |
| GO:0004540 | ribonuclease activity | 20.0000 | 4 | yes |
| GO:0016891 | endoribonuclease activity, producing 5-phosphomonoesters | 20.0000 | 6 | yes |
| GO:0016893 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5-phosphomonoesters | 20.0000 | 6 | yes |
| GO:0004526 | ribonuclease P activity | 13.3333 | 6 | yes |
| GO:0004549 | tRNA-specific ribonuclease activity | 13.3333 | 5 | yes |
| GO:0033204 | ribonuclease P RNA binding | 13.3333 | 5 | yes |
| GO:0140101 | catalytic activity, acting on a tRNA | 13.3333 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in RPP29_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 53.3333 | 4 | no |
| GO:0090304 | nucleic acid metabolic process | 46.6667 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 46.6667 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 46.6667 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 46.6667 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 46.6667 | 4 | no |
| GO:0006396 | RNA processing | 40.0000 | 6 | yes |
| GO:0016070 | RNA metabolic process | 40.0000 | 5 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 40.0000 | 6 | no |
| GO:0009889 | regulation of biosynthetic process | 40.0000 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 40.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 40.0000 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 40.0000 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 40.0000 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 40.0000 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 40.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 40.0000 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 40.0000 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 40.0000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 40.0000 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 40.0000 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 40.0000 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 40.0000 | 6 | no |
| GO:0010646 | regulation of cell communication | 33.3333 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 33.3333 | 7 | no |
| GO:0022607 | cellular component assembly | 33.3333 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 33.3333 | 4 | no |
| GO:0043933 | protein-containing complex organization | 33.3333 | 4 | no |
| GO:0008104 | protein localization | 33.3333 | 4 | no |
| GO:0006399 | tRNA metabolic process | 26.6667 | 7 | yes |
| GO:0034470 | ncRNA processing | 26.6667 | 7 | yes |
| GO:0034660 | ncRNA metabolic process | 26.6667 | 6 | yes |
| GO:0001932 | regulation of protein phosphorylation | 26.6667 | 7 | no |
| GO:0009893 | positive regulation of metabolic process | 26.6667 | 4 | no |
| GO:0009966 | regulation of signal transduction | 26.6667 | 4 | no |
| GO:0010564 | regulation of cell cycle process | 26.6667 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 26.6667 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 26.6667 | 6 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 26.6667 | 5 | no |
| GO:0031399 | regulation of protein modification process | 26.6667 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 26.6667 | 7 | no |
| GO:0051128 | regulation of cellular component organization | 26.6667 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 26.6667 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 26.6667 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.6667 | 6 | no |
| GO:0051248 | negative regulation of protein metabolic process | 26.6667 | 6 | no |
| GO:0051726 | regulation of cell cycle | 26.6667 | 4 | no |
| GO:1901987 | regulation of cell cycle phase transition | 26.6667 | 6 | no |
| GO:0065003 | protein-containing complex assembly | 26.6667 | 5 | no |
| GO:0000966 | RNA 5-end processing | 20.0000 | 7 | yes |
| GO:0008033 | tRNA processing | 20.0000 | 8 | yes |
| GO:0099116 | tRNA 5-end processing | 20.0000 | 8 | yes |
| GO:0001682 | tRNA 5-leader removal | 13.3333 | 9 | yes |
| GO:0006364 | rRNA processing | 13.3333 | 8 | yes |
| GO:0016072 | rRNA metabolic process | 13.3333 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RPP14_HUMAN | [view interactions] | Low throughput | no | no |
| POP7_HUMAN | [view interactions] | Low throughput | no | yes |
| RPP21_HUMAN | [view interactions] | Low throughput | no | no |
| NEPRO_HUMAN | [view interactions] | Low throughput | no | no |
| RPP40_HUMAN | [view interactions] | Low throughput | no | no |
| RPP25_HUMAN | [view interactions] | Low throughput | no | yes |
| POP1_HUMAN | [view interactions] | Low throughput | no | no |
| POP5_HUMAN | [view interactions] | Low throughput | no | no |
| RPP30_HUMAN | [view interactions] | Low throughput | no | yes |
| RPP38_HUMAN | [view interactions] | Low throughput | no | yes |
| GLU2B_HUMAN | [view interactions] | High throughput | no | yes |
| NDK8_HUMAN | [view interactions] | High throughput | no | no |
| PR15A_HUMAN | [view interactions] | High throughput | no | yes |
| RPP29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBWD1_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| PCDA3_HUMAN | [view interactions] | High throughput | no | no |
| PCDGG_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KALM_HUMAN | [view interactions] | High throughput | no | no |
| HIBCH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HFE_HUMAN | [view interactions] | High throughput | no | yes |
| CBX6_HUMAN | [view interactions] | High throughput | no | yes |
| FRIL_HUMAN | [view interactions] | High throughput | no | yes |
| NPM3_HUMAN | [view interactions] | High throughput | no | yes |
| RRP5_HUMAN | [view interactions] | High throughput | no | yes |
| TFR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| CHM2A_HUMAN | [view interactions] | High throughput | no | yes |
| RAMP3_HUMAN | [view interactions] | High throughput | no | no |
| TRAK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN467_HUMAN | [view interactions] | High throughput | no | no |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TICN2_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| RPA34_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| RL10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP4_HUMAN | [view interactions] | High throughput | no | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S10A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TOIP2_HUMAN | [view interactions] | High throughput | no | no |
| VSIG4_HUMAN | [view interactions] | High throughput | no | no |
| I13R2_HUMAN | [view interactions] | High throughput | no | no |
| I20RA_HUMAN | [view interactions] | High throughput | no | no |
| PCD20_HUMAN | [view interactions] | High throughput | no | no |
| CADH5_HUMAN | [view interactions] | High throughput | no | yes |
| RBM4_HUMAN | [view interactions] | High throughput | no | yes |
| VTNC_HUMAN | [view interactions] | High throughput | no | no |
| RL18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM4B_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSTF1_HUMAN | [view interactions] | High throughput | no | yes |
| RP25L_HUMAN | [view interactions] | High throughput | no | yes |
| CR021_HUMAN | [view interactions] | High throughput | no | no |
| DCAM_HUMAN | [view interactions] | High throughput | no | yes |
| CLP1_HUMAN | [view interactions] | Computational | no | yes |
| TRBP2_HUMAN | [view interactions] | Computational | no | yes |
| MRPP3_HUMAN | [view interactions] | Computational | no | yes |
| DICER_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HCD2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| AGO2_HUMAN | [view interactions] | Computational | no | yes |