KC1D_HUMAN
Evidence for PS localization
Functions
Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, determines the circadian period length through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. YAP1 phosphorylation promotes its SCF(beta-TRCP) E3 ubiquitin ligase-mediated ubiquitination and subsequent degradation. DNMT1 phosphorylation reduces its DNA-binding activity. Phosphorylation of ESR1 and AIB1/NCOA3 stimulates their activity and coactivation. Phosphorylation of DVL2 and DVL3 regulates WNT3A signaling pathway that controls neurite outgrowth. EIF6 phosphorylation promotes its nuclear export. Triggers down-regulation of dopamine receptors in the forebrain. Activates DCK in vitro by phosphorylation. TOP2A phosphorylation favors DNA cleavable complex formation. May regulate the formation of the mitotic spindle apparatus in extravillous trophoblast. Modulates connexin-43/GJA1 gap junction assembly by phosphorylation. Probably involved in lymphocyte physiology. Regulates fast synaptic transmission mediated by glutamate. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in KC1D_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 41.0000 | 4 | no |
| GO:0045296 | cadherin binding | 19.0000 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 17.0000 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 17.0000 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 15.0000 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 14.0000 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 14.0000 | 5 | yes |
| GO:0005524 | ATP binding | 12.0000 | 5 | yes |
| GO:0016301 | kinase activity | 9.0000 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 9.0000 | 4 | yes |
| GO:0004674 | protein serine/threonine kinase activity | 8.0000 | 4 | yes |
| GO:0004712 | protein serine/threonine/tyrosine kinase activity | 8.0000 | 4 | yes |
| GO:0106310 | protein serine kinase activity | 8.0000 | 4 | yes |
| GO:0050321 | tau-protein kinase activity | 4.0000 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in KC1D_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 52.0000 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 51.0000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 48.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 48.0000 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 48.0000 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 47.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 46.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 41.0000 | 4 | yes |
| GO:0006996 | organelle organization | 38.0000 | 4 | yes |
| GO:0010468 | regulation of gene expression | 36.0000 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 36.0000 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 34.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 33.0000 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.0000 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.0000 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 32.0000 | 4 | no |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 31.0000 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 31.0000 | 5 | no |
| GO:0008104 | protein localization | 31.0000 | 4 | yes |
| GO:0009059 | macromolecule biosynthetic process | 30.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 30.0000 | 4 | yes |
| GO:0051049 | regulation of transport | 29.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.0000 | 5 | yes |
| GO:0034645 | cellular macromolecule biosynthetic process | 28.0000 | 4 | no |
| GO:0043603 | cellular amide metabolic process | 28.0000 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 28.0000 | 4 | no |
| GO:0071702 | organic substance transport | 28.0000 | 4 | no |
| GO:0002181 | cytoplasmic translation | 27.0000 | 5 | no |
| GO:0006412 | translation | 27.0000 | 4 | no |
| GO:0006518 | peptide metabolic process | 27.0000 | 4 | no |
| GO:0043043 | peptide biosynthetic process | 27.0000 | 5 | no |
| GO:0043604 | amide biosynthetic process | 27.0000 | 5 | no |
| GO:0071705 | nitrogen compound transport | 27.0000 | 4 | no |
| GO:0031399 | regulation of protein modification process | 27.0000 | 6 | yes |
| GO:0036211 | protein modification process | 27.0000 | 4 | yes |
| GO:0043412 | macromolecule modification | 27.0000 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 26.0000 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 25.0000 | 6 | yes |
| GO:0023056 | positive regulation of signaling | 25.0000 | 4 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 25.0000 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 24.0000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 24.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 24.0000 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 24.0000 | 4 | yes |
| GO:0010941 | regulation of cell death | 23.0000 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.0000 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.0000 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 23.0000 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.0000 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 22.0000 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 22.0000 | 5 | no |
| GO:0032880 | regulation of protein localization | 22.0000 | 5 | no |
| GO:0033043 | regulation of organelle organization | 22.0000 | 5 | no |
| GO:0015031 | protein transport | 22.0000 | 4 | no |
| GO:0009894 | regulation of catabolic process | 22.0000 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 22.0000 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 22.0000 | 6 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 21.0000 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 21.0000 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 21.0000 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 21.0000 | 5 | yes |
| GO:0042325 | regulation of phosphorylation | 21.0000 | 7 | yes |
| GO:0043933 | protein-containing complex organization | 20.0000 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 20.0000 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 19.0000 | 7 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 19.0000 | 4 | yes |
| GO:0031329 | regulation of cellular catabolic process | 19.0000 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 18.0000 | 5 | yes |
| GO:0030030 | cell projection organization | 18.0000 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 17.0000 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 17.0000 | 4 | yes |
| GO:0030162 | regulation of proteolysis | 16.0000 | 6 | yes |
| GO:0065003 | protein-containing complex assembly | 16.0000 | 5 | yes |
| GO:0031401 | positive regulation of protein modification process | 15.0000 | 7 | yes |
| GO:0042176 | regulation of protein catabolic process | 15.0000 | 5 | yes |
| GO:0045597 | positive regulation of cell differentiation | 14.0000 | 5 | yes |
| GO:0033365 | protein localization to organelle | 13.0000 | 5 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 12.0000 | 6 | yes |
| GO:0042327 | positive regulation of phosphorylation | 12.0000 | 8 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 12.0000 | 7 | yes |
| GO:0070925 | organelle assembly | 12.0000 | 5 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 11.0000 | 8 | yes |
| GO:0006468 | protein phosphorylation | 11.0000 | 5 | yes |
| GO:0009896 | positive regulation of catabolic process | 11.0000 | 5 | yes |
| GO:0016310 | phosphorylation | 11.0000 | 5 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 11.0000 | 5 | yes |
| GO:0045862 | positive regulation of proteolysis | 11.0000 | 7 | yes |
| GO:1903050 | regulation of proteolysis involved in protein catabolic process | 10.0000 | 7 | yes |
| GO:0045664 | regulation of neuron differentiation | 10.0000 | 5 | yes |
| GO:0045732 | positive regulation of protein catabolic process | 10.0000 | 6 | yes |
| GO:0060828 | regulation of canonical Wnt signaling pathway | 10.0000 | 6 | yes |
| GO:0061136 | regulation of proteasomal protein catabolic process | 10.0000 | 6 | yes |
| GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 9.0000 | 6 | yes |
| GO:0018105 | peptidyl-serine phosphorylation | 9.0000 | 6 | yes |
| GO:0018193 | peptidyl-amino acid modification | 9.0000 | 5 | yes |
| GO:0018209 | peptidyl-serine modification | 9.0000 | 6 | yes |
| GO:0031331 | positive regulation of cellular catabolic process | 9.0000 | 6 | yes |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 9.0000 | 7 | yes |
| GO:0140694 | non-membrane-bounded organelle assembly | 7.0000 | 6 | yes |
| GO:1901800 | positive regulation of proteasomal protein catabolic process | 7.0000 | 7 | yes |
| GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 7.0000 | 8 | yes |
| GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | 7.0000 | 7 | yes |
| GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 7.0000 | 8 | yes |
| GO:0070848 | response to growth factor | 7.0000 | 4 | yes |
| GO:0071363 | cellular response to growth factor stimulus | 7.0000 | 5 | yes |
| GO:0120031 | plasma membrane bounded cell projection assembly | 6.0000 | 6 | yes |
| GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 6.0000 | 4 | yes |
| GO:0016055 | Wnt signaling pathway | 6.0000 | 5 | yes |
| GO:0030031 | cell projection assembly | 6.0000 | 5 | yes |
| GO:1990090 | cellular response to nerve growth factor stimulus | 5.0000 | 4 | yes |
| GO:0007030 | Golgi organization | 5.0000 | 5 | yes |
| GO:0090263 | positive regulation of canonical Wnt signaling pathway | 4.0000 | 7 | yes |
| GO:1904338 | regulation of dopaminergic neuron differentiation | 4.0000 | 6 | yes |
| GO:0007020 | microtubule nucleation | 4.0000 | 4 | yes |
| GO:0030177 | positive regulation of Wnt signaling pathway | 4.0000 | 6 | yes |
| GO:0044782 | cilium organization | 4.0000 | 5 | yes |
| GO:0045666 | positive regulation of neuron differentiation | 4.0000 | 6 | yes |
| GO:0060271 | cilium assembly | 4.0000 | 6 | yes |
| GO:0072698 | protein localization to microtubule cytoskeleton | 3.0000 | 7 | yes |
| GO:1904340 | positive regulation of dopaminergic neuron differentiation | 3.0000 | 7 | yes |
| GO:1904956 | regulation of midbrain dopaminergic neuron differentiation | 3.0000 | 7 | yes |
| GO:1904958 | positive regulation of midbrain dopaminergic neuron differentiation | 3.0000 | 8 | yes |
| GO:1905424 | regulation of Wnt-mediated midbrain dopaminergic neuron differentiation | 3.0000 | 6 | yes |
| GO:1905426 | positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation | 3.0000 | 7 | yes |
| GO:2000050 | regulation of non-canonical Wnt signaling pathway | 3.0000 | 6 | yes |
| GO:2000052 | positive regulation of non-canonical Wnt signaling pathway | 3.0000 | 7 | yes |
| GO:0016050 | vesicle organization | 3.0000 | 5 | yes |
| GO:0044380 | protein localization to cytoskeleton | 3.0000 | 6 | yes |
| GO:0051225 | spindle assembly | 3.0000 | 4 | yes |
| GO:1905508 | protein localization to microtubule organizing center | 2.0000 | 8 | yes |
| GO:1905515 | non-motile cilium assembly | 2.0000 | 7 | yes |
| GO:0006901 | vesicle coating | 2.0000 | 6 | yes |
| GO:0034067 | protein localization to Golgi apparatus | 2.0000 | 6 | yes |
| GO:0048208 | COPII vesicle coating | 2.0000 | 6 | yes |
| GO:0061512 | protein localization to cilium | 2.0000 | 6 | yes |
| GO:0071539 | protein localization to centrosome | 2.0000 | 9 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in KC1D_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 2.0000 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DVL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| PML_HUMAN | [view interactions] | Low throughput | no | yes |
| FHL1_HUMAN | [view interactions] | Low throughput | no | no |
| MTSS1_HUMAN | [view interactions] | Low throughput | no | no |
| NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PPP6_HUMAN | [view interactions] | Low throughput | no | yes |
| KMT5A_HUMAN | [view interactions] | Low throughput | no | no |
| PPP5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SMCA4_HUMAN | [view interactions] | Low throughput | no | yes |
| TOP2B_HUMAN | [view interactions] | Low throughput | no | yes |
| TLE5_HUMAN | [view interactions] | Low throughput | no | no |
| KC1D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PER2_HUMAN | [view interactions] | Low throughput | no | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MDM2_HUMAN | [view interactions] | Low throughput | no | yes |
| ATM_HUMAN | [view interactions] | Low throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CLK2_HUMAN | [view interactions] | Low throughput | no | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| CREB1_HUMAN | [view interactions] | Low throughput | no | yes |
| PER1_HUMAN | [view interactions] | Low throughput | no | no |
| PDPK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AKAP9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P63_HUMAN | [view interactions] | Low throughput | no | no |
| SNAPN_HUMAN | [view interactions] | Low throughput | no | yes |
| P53_HUMAN | [view interactions] | Low throughput | no | no |
| TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAP4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MAP1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCOA3_HUMAN | [view interactions] | Low throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DVL2_HUMAN | [view interactions] | Low throughput | no | yes |
| LZTS2_HUMAN | [view interactions] | Low throughput | no | no |
| SMAD2_HUMAN | [view interactions] | Low throughput | no | yes |
| SMAD3_HUMAN | [view interactions] | Low throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DBND2_HUMAN | [view interactions] | Low throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTN14_HUMAN | [view interactions] | High throughput | no | yes |
| FOXP3_HUMAN | [view interactions] | High throughput | no | no |
| SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| MAF1_HUMAN | [view interactions] | High throughput | no | no |
| CCG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRA2A_HUMAN | [view interactions] | High throughput | no | yes |
| KCD17_HUMAN | [view interactions] | High throughput | no | yes |
| TX264_HUMAN | [view interactions] | High throughput | no | no |
| CCG4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| XRP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MICU2_HUMAN | [view interactions] | High throughput | no | yes |
| LRAD4_HUMAN | [view interactions] | High throughput | no | yes |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GEMI7_HUMAN | [view interactions] | High throughput | no | no |
| KAP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RT29_HUMAN | [view interactions] | High throughput | no | yes |
| AXIN1_HUMAN | [view interactions] | High throughput | no | yes |
| CEP43_HUMAN | [view interactions] | High throughput | no | no |
| TYW3_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC9_HUMAN | [view interactions] | High throughput | no | yes |
| KNL1_HUMAN | [view interactions] | High throughput | no | no |
| NFAC1_HUMAN | [view interactions] | High throughput | no | no |
| NFAC2_HUMAN | [view interactions] | High throughput | no | yes |
| ATOH1_HUMAN | [view interactions] | High throughput | no | no |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| TYDP1_HUMAN | [view interactions] | High throughput | no | no |
| SSMM1_HUMAN | [view interactions] | High throughput | no | no |
| NXF2_HUMAN | [view interactions] | High throughput | no | no |
| HMMR_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| LNX1_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR4_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYDE2_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NSRP1_HUMAN | [view interactions] | High throughput | no | yes |
| TYY1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX2L_HUMAN | [view interactions] | High throughput | no | no |
| DDX42_HUMAN | [view interactions] | High throughput | no | yes |
| PP1RA_HUMAN | [view interactions] | High throughput | no | yes |
| NUFP2_HUMAN | [view interactions] | High throughput | no | no |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| FA76B_HUMAN | [view interactions] | High throughput | no | no |
| MMTA2_HUMAN | [view interactions] | High throughput | no | yes |
| PPIL4_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF7_HUMAN | [view interactions] | High throughput | no | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMRP_HUMAN | [view interactions] | High throughput | no | yes |
| RBM25_HUMAN | [view interactions] | High throughput | no | yes |
| SNIP1_HUMAN | [view interactions] | High throughput | no | no |
| TAF2_HUMAN | [view interactions] | High throughput | no | no |
| RB15B_HUMAN | [view interactions] | High throughput | no | yes |
| POP1_HUMAN | [view interactions] | High throughput | no | no |
| DDX56_HUMAN | [view interactions] | High throughput | no | yes |
| PR40A_HUMAN | [view interactions] | High throughput | no | yes |
| FA98A_HUMAN | [view interactions] | High throughput | no | no |
| SF3B4_HUMAN | [view interactions] | High throughput | no | yes |
| FIP1_HUMAN | [view interactions] | High throughput | no | yes |
| CBX4_HUMAN | [view interactions] | High throughput | no | yes |
| PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| CCNT2_HUMAN | [view interactions] | High throughput | no | yes |
| TOX4_HUMAN | [view interactions] | High throughput | no | yes |
| GTPB4_HUMAN | [view interactions] | High throughput | no | yes |
| PRP4B_HUMAN | [view interactions] | High throughput | no | yes |
| DCA13_HUMAN | [view interactions] | High throughput | no | yes |
| HXA5_HUMAN | [view interactions] | High throughput | no | no |
| MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
| FIZ1_HUMAN | [view interactions] | High throughput | no | no |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FA76A_HUMAN | [view interactions] | High throughput | no | yes |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PR38A_HUMAN | [view interactions] | High throughput | no | no |
| MECP2_HUMAN | [view interactions] | High throughput | no | yes |
| SNUT1_HUMAN | [view interactions] | High throughput | no | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| ATG4B_HUMAN | [view interactions] | High throughput | no | yes |
| F110D_HUMAN | [view interactions] | High throughput | no | no |
| TMM74_HUMAN | [view interactions] | High throughput | no | no |
| FRIL_HUMAN | [view interactions] | High throughput | no | yes |
| TMTC4_HUMAN | [view interactions] | High throughput | no | yes |
| ORML3_HUMAN | [view interactions] | High throughput | no | no |
| SLAF6_HUMAN | [view interactions] | High throughput | no | no |
| NGN3_HUMAN | [view interactions] | High throughput | no | no |
| FOS_HUMAN | [view interactions] | High throughput | no | yes |
| SHFL_HUMAN | [view interactions] | High throughput | no | yes |
| PROF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAV1_HUMAN | [view interactions] | High throughput | no | yes |
| IMDH1_HUMAN | [view interactions] | High throughput | no | yes |
| CF141_HUMAN | [view interactions] | High throughput | no | no |
| DRD3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | yes |
| NPSR1_HUMAN | [view interactions] | High throughput | no | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSR1_HUMAN | [view interactions] | High throughput | no | no |
| PP14A_HUMAN | [view interactions] | High throughput | no | yes |
| CRML_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ULK2_HUMAN | [view interactions] | High throughput | no | yes |
| HAKAI_HUMAN | [view interactions] | High throughput | no | yes |
| SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
| LURA1_HUMAN | [view interactions] | High throughput | no | yes |
| CRY1_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1A_HUMAN | [view interactions] | High throughput | no | yes |
| BCL7C_HUMAN | [view interactions] | High throughput | no | yes |
| S35E1_HUMAN | [view interactions] | High throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP16_HUMAN | [view interactions] | High throughput | no | yes |
| NOB1_HUMAN | [view interactions] | High throughput | no | yes |
| HMGN3_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1B_HUMAN | [view interactions] | High throughput | no | yes |
| KAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| RAIN_HUMAN | [view interactions] | High throughput | no | no |
| RMD3_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| FA83H_HUMAN | [view interactions] | High throughput | no | yes |
| TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
| ITA1_HUMAN | [view interactions] | High throughput | no | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| CD109_HUMAN | [view interactions] | High throughput | no | no |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| FA83A_HUMAN | [view interactions] | High throughput | no | no |
| FA83B_HUMAN | [view interactions] | High throughput | no | no |
| FA83E_HUMAN | [view interactions] | High throughput | no | no |
| FA83G_HUMAN | [view interactions] | High throughput | no | no |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARGL1_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| F199X_HUMAN | [view interactions] | High throughput | no | yes |
| SNX24_HUMAN | [view interactions] | High throughput | no | yes |
| NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBPL_HUMAN | [view interactions] | High throughput | no | yes |
| STOX2_HUMAN | [view interactions] | High throughput | no | no |
| ABHDA_HUMAN | [view interactions] | High throughput | no | yes |
| ELP3_HUMAN | [view interactions] | High throughput | no | no |
| DBND1_HUMAN | [view interactions] | High throughput | no | yes |
| FA83D_HUMAN | [view interactions] | High throughput | no | no |
| UN45A_HUMAN | [view interactions] | High throughput | no | yes |
| F110A_HUMAN | [view interactions] | High throughput | no | yes |
| SNX22_HUMAN | [view interactions] | High throughput | no | no |
| LTV1_HUMAN | [view interactions] | High throughput | no | yes |
| PTCD3_HUMAN | [view interactions] | High throughput | no | yes |
| ANR49_HUMAN | [view interactions] | High throughput | no | yes |
| F110B_HUMAN | [view interactions] | High throughput | no | yes |
| VP13B_HUMAN | [view interactions] | High throughput | no | no |
| RHG22_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELP2_HUMAN | [view interactions] | High throughput | no | yes |
| UBR4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLH22_HUMAN | [view interactions] | High throughput | no | no |
| CRY2_HUMAN | [view interactions] | High throughput | no | yes |
| F110C_HUMAN | [view interactions] | High throughput | no | yes |
| ECM1_HUMAN | [view interactions] | High throughput | no | no |
| RRS1_HUMAN | [view interactions] | High throughput | no | yes |
| GAPD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BYST_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC4_HUMAN | [view interactions] | High throughput | no | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RT34_HUMAN | [view interactions] | High throughput | no | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RD23B_HUMAN | [view interactions] | High throughput | no | yes |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| DNLI4_HUMAN | [view interactions] | High throughput | no | yes |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELP1_HUMAN | [view interactions] | High throughput | no | yes |
| SC16A_HUMAN | [view interactions] | High throughput | no | yes |
| ZSWM8_HUMAN | [view interactions] | High throughput | no | yes |
| T131L_HUMAN | [view interactions] | High throughput | no | yes |
| CCNA1_HUMAN | [view interactions] | High throughput | no | no |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| DACT2_HUMAN | [view interactions] | High throughput | no | yes |
| DACT3_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN_HUMAN | [view interactions] | High throughput | no | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| DVL3_HUMAN | [view interactions] | High throughput | no | yes |
| TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN618_HUMAN | [view interactions] | High throughput | no | no |
| TRIM3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IKZF4_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT8A_HUMAN | [view interactions] | High throughput | no | yes |
| PAK5_HUMAN | [view interactions] | High throughput | no | yes |
| EVI5_HUMAN | [view interactions] | High throughput | no | yes |
| DRIC1_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CCNT1_HUMAN | [view interactions] | High throughput | no | yes |
| CIAO1_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| SP100_HUMAN | [view interactions] | High throughput | no | no |
| PTPRD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BACE1_HUMAN | [view interactions] | High throughput | no | yes |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| FADD_HUMAN | [view interactions] | High throughput | no | yes |
| NEMO_HUMAN | [view interactions] | High throughput | no | yes |
| TANK_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| JUPI2_HUMAN | [view interactions] | High throughput | no | no |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| ZDH17_HUMAN | [view interactions] | High throughput | no | yes |
| CCD14_HUMAN | [view interactions] | High throughput | no | yes |
| TGFR1_HUMAN | [view interactions] | High throughput | no | no |
| RS24_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| YAP1_HUMAN | [view interactions] | Computational | no | yes |
| RS14_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS11_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS15_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| UBB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS8_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| 1433B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RPP25_HUMAN | [view interactions] | Computational | no | yes |
| RPP40_HUMAN | [view interactions] | Computational | no | no |
| BUD23_HUMAN | [view interactions] | Computational | no | yes |
| RPP30_HUMAN | [view interactions] | Computational | no | yes |
| BMAL1_HUMAN | [view interactions] | Computational | no | yes |
| RS9_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GLI2_HUMAN | [view interactions] | Computational | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS12_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RIOK3_HUMAN | [view interactions] | Computational | no | yes |
| PER3_HUMAN | [view interactions] | Computational | no | yes |
| RS5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SMO_HUMAN | [view interactions] | Computational | no | yes |
| RS6_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FBXL3_HUMAN | [view interactions] | Computational | no | no |
| RS25_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS26_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RIOK1_HUMAN | [view interactions] | Computational | no | yes |
| RS16_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS3A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS20_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS29_HUMAN | [view interactions] | Computational | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RPP38_HUMAN | [view interactions] | Computational | no | yes |
| RS23_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS18_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RPP21_HUMAN | [view interactions] | Computational | no | no |
| RS21_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FBW1A_HUMAN | [view interactions] | Computational | no | yes |
| RS15A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FOXO1_HUMAN | [view interactions] | Computational | no | yes |
| CD5R1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| 1433S_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS10_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RPP14_HUMAN | [view interactions] | Computational | no | no |
| 1433T_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS30_HUMAN | [view interactions] | Computational | no | yes |
| PP1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PNO1_HUMAN | [view interactions] | Computational | no | no |
| CDK5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NPAS2_HUMAN | [view interactions] | Computational | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RIOK2_HUMAN | [view interactions] | Computational | no | yes |
| PPR1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CLOCK_HUMAN | [view interactions] | Computational | no | yes |
| WWTR1_HUMAN | [view interactions] | Computational | no | yes |
| PP1G_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS28_HUMAN | [view entry] [view interactions] | Computational | yes | yes |