UBR4_HUMAN
Evidence for PS localization
Functions
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in UBR4_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 34.8837 | 4 | no |
| GO:0043169 | cation binding | 33.7209 | 4 | yes |
| GO:0046872 | metal ion binding | 33.7209 | 5 | yes |
| GO:0043168 | anion binding | 29.0698 | 4 | no |
| GO:0000166 | nucleotide binding | 27.9070 | 4 | no |
| GO:0017076 | purine nucleotide binding | 27.9070 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 27.9070 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.7442 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 22.0930 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 22.0930 | 5 | no |
| GO:0019900 | kinase binding | 20.9302 | 4 | no |
| GO:0005524 | ATP binding | 20.9302 | 5 | no |
| GO:0046914 | transition metal ion binding | 11.6279 | 6 | yes |
| GO:0008270 | zinc ion binding | 9.3023 | 7 | yes |
| GO:0016755 | aminoacyltransferase activity | 5.8140 | 4 | yes |
| GO:0004842 | ubiquitin-protein transferase activity | 4.6512 | 4 | yes |
| GO:0061630 | ubiquitin protein ligase activity | 4.6512 | 5 | yes |
| GO:0061659 | ubiquitin-like protein ligase activity | 4.6512 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in UBR4_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 63.9535 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 52.3256 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 48.8372 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 47.6744 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 47.6744 | 4 | no |
| GO:0010646 | regulation of cell communication | 47.6744 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 41.8605 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 41.8605 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 40.6977 | 4 | no |
| GO:0009966 | regulation of signal transduction | 39.5349 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 37.2093 | 4 | yes |
| GO:0006996 | organelle organization | 37.2093 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 37.2093 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 36.0465 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 34.8837 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 34.8837 | 5 | no |
| GO:0022607 | cellular component assembly | 33.7209 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 33.7209 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 33.7209 | 6 | no |
| GO:0010468 | regulation of gene expression | 33.7209 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.5581 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 31.3953 | 5 | no |
| GO:0031399 | regulation of protein modification process | 30.2326 | 6 | no |
| GO:0008104 | protein localization | 29.0698 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.0698 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 29.0698 | 5 | no |
| GO:0023056 | positive regulation of signaling | 29.0698 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 29.0698 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 27.9070 | 4 | no |
| GO:0009894 | regulation of catabolic process | 26.7442 | 4 | no |
| GO:0051049 | regulation of transport | 26.7442 | 4 | no |
| GO:0036211 | protein modification process | 25.5814 | 4 | yes |
| GO:0043412 | macromolecule modification | 25.5814 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 24.4186 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 24.4186 | 4 | no |
| GO:0060341 | regulation of cellular localization | 24.4186 | 4 | no |
| GO:0071310 | cellular response to organic substance | 24.4186 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 23.2558 | 7 | no |
| GO:0043933 | protein-containing complex organization | 23.2558 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 23.2558 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.2558 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 23.2558 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.2558 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 23.2558 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 22.0930 | 5 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.0930 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 22.0930 | 5 | no |
| GO:0033043 | regulation of organelle organization | 22.0930 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 22.0930 | 7 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.0930 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 22.0930 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 22.0930 | 4 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 20.9302 | 6 | no |
| GO:0001932 | regulation of protein phosphorylation | 20.9302 | 7 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 20.9302 | 6 | no |
| GO:0032880 | regulation of protein localization | 20.9302 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 20.9302 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 20.9302 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 20.9302 | 5 | no |
| GO:0043687 | post-translational protein modification | 15.1163 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 15.1163 | 6 | yes |
| GO:0009057 | macromolecule catabolic process | 12.7907 | 4 | yes |
| GO:0032446 | protein modification by small protein conjugation | 11.6279 | 7 | yes |
| GO:0006508 | proteolysis | 10.4651 | 4 | yes |
| GO:0019941 | modification-dependent protein catabolic process | 9.3023 | 6 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 9.3023 | 5 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 9.3023 | 5 | yes |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 8.1395 | 7 | yes |
| GO:0016567 | protein ubiquitination | 8.1395 | 8 | yes |
| GO:0062012 | regulation of small molecule metabolic process | 6.9767 | 4 | yes |
| GO:0019216 | regulation of lipid metabolic process | 4.6512 | 5 | yes |
| GO:0010565 | regulation of cellular ketone metabolic process | 2.3256 | 5 | yes |
| GO:0019217 | regulation of fatty acid metabolic process | 2.3256 | 6 | yes |
| GO:0046890 | regulation of lipid biosynthetic process | 2.3256 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ACE2_HUMAN | [view interactions] | Low throughput | no | no |
| EZH2_HUMAN | [view interactions] | Low throughput | no | no |
| CALM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SPTCS_HUMAN | [view interactions] | Low throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OTUD5_HUMAN | [view interactions] | Low throughput | no | yes |
| RB_HUMAN | [view interactions] | Low throughput | no | yes |
| STAT2_HUMAN | [view interactions] | Low throughput | no | yes |
| ACLY_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCMF1_HUMAN | [view interactions] | Low throughput | no | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CDCA5_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| PSB2_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| ABHDA_HUMAN | [view interactions] | High throughput | no | yes |
| LPD6B_HUMAN | [view interactions] | High throughput | no | no |
| LY65C_HUMAN | [view interactions] | High throughput | no | no |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| ZB10P_HUMAN | [view interactions] | High throughput | no | no |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELP2_HUMAN | [view interactions] | High throughput | no | yes |
| ZHX1R_HUMAN | [view interactions] | High throughput | no | yes |
| DB125_HUMAN | [view interactions] | High throughput | no | no |
| RDD1_HUMAN | [view interactions] | High throughput | no | no |
| TIMP3_HUMAN | [view interactions] | High throughput | no | no |
| PPR29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTX3_HUMAN | [view interactions] | High throughput | no | no |
| RAPSN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FBXW5_HUMAN | [view interactions] | High throughput | no | no |
| UPP1_HUMAN | [view interactions] | High throughput | no | no |
| MIOX_HUMAN | [view interactions] | High throughput | no | no |
| SOLH1_HUMAN | [view interactions] | High throughput | no | no |
| CAN10_HUMAN | [view interactions] | High throughput | no | yes |
| CB27A_HUMAN | [view interactions] | High throughput | no | no |
| CB27B_HUMAN | [view interactions] | High throughput | no | no |
| NDK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPM1M_HUMAN | [view interactions] | High throughput | no | yes |
| EMIL1_HUMAN | [view interactions] | High throughput | no | no |
| ELMO3_HUMAN | [view interactions] | High throughput | no | yes |
| EGFL7_HUMAN | [view interactions] | High throughput | no | yes |
| SYSM_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| TFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| CATB_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| CATS_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| COPZ1_HUMAN | [view interactions] | High throughput | no | no |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| CREM_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KBTB4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SERC5_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| ATAD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO10_HUMAN | [view interactions] | High throughput | no | no |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| ERG_HUMAN | [view interactions] | High throughput | no | yes |
| UB2L3_HUMAN | [view interactions] | High throughput | no | yes |
| UB2D2_HUMAN | [view interactions] | High throughput | no | yes |
| PR40A_HUMAN | [view interactions] | High throughput | no | no |
| ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBE2B_HUMAN | [view interactions] | High throughput | no | no |
| ITB2_HUMAN | [view interactions] | High throughput | no | no |
| SRGN_HUMAN | [view interactions] | High throughput | no | no |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTR1A_HUMAN | [view interactions] | High throughput | no | no |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBXN7_HUMAN | [view interactions] | High throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAF2_HUMAN | [view interactions] | High throughput | no | yes |
| U520_HUMAN | [view interactions] | High throughput | no | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBXN1_HUMAN | [view interactions] | High throughput | no | no |
| ZEB1_HUMAN | [view interactions] | High throughput | no | yes |
| NSF1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| SYLC_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC2_HUMAN | [view interactions] | High throughput | no | yes |
| PHOCN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS8_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| PRS10_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| ECM29_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| KPCD1_HUMAN | [view interactions] | High throughput | no | yes |
| DDX46_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF2P_HUMAN | [view interactions] | High throughput | no | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SBNO1_HUMAN | [view interactions] | High throughput | no | yes |
| IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PK3CA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SART3_HUMAN | [view interactions] | High throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| ATP9A_HUMAN | [view interactions] | High throughput | no | yes |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| DHX29_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HERC4_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| LIPT2_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL15_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HG2A_HUMAN | [view interactions] | High throughput | no | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| DOC11_HUMAN | [view interactions] | High throughput | no | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| SPT5H_HUMAN | [view interactions] | High throughput | no | yes |
| KPSH1_HUMAN | [view interactions] | High throughput | no | yes |
| SR140_HUMAN | [view interactions] | High throughput | no | yes |
| BCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| KC1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYVC_HUMAN | [view interactions] | High throughput | no | yes |
| STK38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T2FA_HUMAN | [view interactions] | High throughput | no | yes |
| ST32C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UHMK1_HUMAN | [view interactions] | High throughput | no | no |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRBP2_HUMAN | [view interactions] | High throughput | no | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPKL1_HUMAN | [view interactions] | High throughput | no | yes |
| 5NTC_HUMAN | [view interactions] | High throughput | no | yes |
| TAL1_HUMAN | [view interactions] | High throughput | no | no |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRSF4_HUMAN | [view interactions] | High throughput | no | yes |
| EPHB6_HUMAN | [view interactions] | High throughput | no | no |
| IFT88_HUMAN | [view interactions] | High throughput | no | no |
| FGFR2_HUMAN | [view interactions] | High throughput | no | yes |
| IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| SETB1_HUMAN | [view interactions] | High throughput | no | yes |
| PGFRB_HUMAN | [view interactions] | High throughput | no | yes |
| ARI4B_HUMAN | [view interactions] | High throughput | no | yes |
| MCRS1_HUMAN | [view interactions] | High throughput | no | yes |
| WAC2A_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| KI21A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BD1L1_HUMAN | [view interactions] | High throughput | no | yes |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRE1_HUMAN | [view interactions] | High throughput | no | yes |
| KBP_HUMAN | [view interactions] | High throughput | no | yes |
| ADA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SIN3A_HUMAN | [view interactions] | High throughput | no | yes |
| AGTR1_HUMAN | [view interactions] | High throughput | no | no |
| WBP11_HUMAN | [view interactions] | High throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARI1_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD6_HUMAN | [view interactions] | High throughput | no | no |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| FOXK1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| FOXK2_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| IFT27_HUMAN | [view interactions] | High throughput | no | yes |
| PRP19_HUMAN | [view interactions] | High throughput | no | yes |
| CHK2_HUMAN | [view interactions] | High throughput | no | yes |
| MFN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSAG1_HUMAN | [view interactions] | High throughput | no | no |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSAG2_HUMAN | [view interactions] | High throughput | no | no |
| RT12_HUMAN | [view interactions] | High throughput | no | yes |
| CI072_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTC3_HUMAN | [view interactions] | High throughput | no | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP13_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| AMOT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AKIP_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| RPA34_HUMAN | [view interactions] | High throughput | no | yes |
| H31_HUMAN | [view interactions] | High throughput | no | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| FLT3_HUMAN | [view interactions] | High throughput | no | no |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| BROMI_HUMAN | [view interactions] | High throughput | no | no |
| RD23B_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| CDN1A_HUMAN | [view interactions] | High throughput | no | no |
| PF21A_HUMAN | [view interactions] | High throughput | no | yes |
| CEP57_HUMAN | [view interactions] | High throughput | no | yes |
| RCOR1_HUMAN | [view interactions] | High throughput | no | yes |
| CP250_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| GCP3_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| CFC1_HUMAN | [view interactions] | High throughput | no | no |
| SPAT1_HUMAN | [view interactions] | High throughput | no | no |
| ANM6_HUMAN | [view interactions] | High throughput | no | yes |
| VEGFD_HUMAN | [view interactions] | High throughput | no | no |
| TFDP3_HUMAN | [view interactions] | High throughput | no | no |
| PGLT1_HUMAN | [view interactions] | High throughput | no | no |
| EDA_HUMAN | [view interactions] | High throughput | no | no |
| EMID1_HUMAN | [view interactions] | High throughput | no | yes |
| CHIA_HUMAN | [view interactions] | High throughput | no | yes |
| TACT_HUMAN | [view interactions] | High throughput | no | no |
| PLPL1_HUMAN | [view interactions] | High throughput | no | no |
| CSHL_HUMAN | [view interactions] | High throughput | no | no |
| CST9_HUMAN | [view interactions] | High throughput | no | no |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| RAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| XRCC3_HUMAN | [view interactions] | High throughput | no | no |
| USF1_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGP_HUMAN | [view interactions] | High throughput | no | no |
| RBP2_HUMAN | [view interactions] | High throughput | no | yes |
| WIZ_HUMAN | [view interactions] | High throughput | no | yes |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GORS1_HUMAN | [view interactions] | High throughput | no | yes |
| PODO_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| DPF3_HUMAN | [view interactions] | High throughput | no | yes |
| MET2A_HUMAN | [view interactions] | High throughput | no | no |
| FSTL4_HUMAN | [view interactions] | High throughput | no | no |
| VMA5A_HUMAN | [view interactions] | High throughput | no | no |
| A1BG_HUMAN | [view interactions] | High throughput | no | no |
| COLI_HUMAN | [view interactions] | High throughput | no | no |
| INSL5_HUMAN | [view interactions] | High throughput | no | no |
| DC2I2_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HYAL1_HUMAN | [view interactions] | High throughput | no | no |
| CRYL1_HUMAN | [view interactions] | High throughput | no | yes |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| CPNE5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CA087_HUMAN | [view interactions] | High throughput | no | no |
| ERMAP_HUMAN | [view interactions] | High throughput | no | yes |
| FUZZY_HUMAN | [view interactions] | High throughput | no | yes |
| SLX1_HUMAN | [view interactions] | High throughput | no | yes |
| MIGA2_HUMAN | [view interactions] | High throughput | no | yes |
| GML_HUMAN | [view interactions] | High throughput | no | no |
| CCNG1_HUMAN | [view interactions] | High throughput | no | yes |
| ACSM5_HUMAN | [view interactions] | High throughput | no | yes |
| TPGS2_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| ZNHI2_HUMAN | [view interactions] | High throughput | no | no |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| RN181_HUMAN | [view interactions] | High throughput | no | no |
| AGO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TXNIP_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| S15A3_HUMAN | [view interactions] | High throughput | no | yes |
| DUS19_HUMAN | [view interactions] | High throughput | no | yes |
| DUS2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |