PPR29_HUMAN
Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in PPR29_HUMAN |
---|---|---|---|---|
GO:0046872 | metal ion binding | 61.5385 | 4 | no |
GO:0019900 | kinase binding | 46.1538 | 4 | no |
GO:0019901 | protein kinase binding | 46.1538 | 5 | no |
GO:0005509 | calcium ion binding | 38.4615 | 5 | no |
GO:0019888 | protein phosphatase regulator activity | 30.7692 | 4 | yes |
GO:0008179 | adenylate cyclase binding | 23.0769 | 4 | no |
GO:0010856 | adenylate cyclase activator activity | 23.0769 | 4 | no |
GO:0019209 | kinase activator activity | 23.0769 | 4 | no |
GO:0019211 | phosphatase activator activity | 23.0769 | 4 | no |
GO:0019887 | protein kinase regulator activity | 23.0769 | 4 | no |
GO:0030295 | protein kinase activator activity | 23.0769 | 5 | no |
GO:0031432 | titin binding | 23.0769 | 4 | no |
GO:0031997 | N-terminal myristoylation domain binding | 23.0769 | 4 | no |
GO:0043539 | protein serine/threonine kinase activator activity | 23.0769 | 6 | no |
GO:0072542 | protein phosphatase activator activity | 23.0769 | 5 | no |
GO:0097718 | disordered domain specific binding | 23.0769 | 4 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in PPR29_HUMAN |
---|---|---|---|---|
GO:0060255 | regulation of macromolecule metabolic process | 76.9231 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 69.2308 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 69.2308 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 69.2308 | 4 | no |
GO:0048522 | positive regulation of cellular process | 69.2308 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 61.5385 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 61.5385 | 5 | no |
GO:0010646 | regulation of cell communication | 61.5385 | 4 | no |
GO:0048523 | negative regulation of cellular process | 61.5385 | 4 | no |
GO:0051049 | regulation of transport | 61.5385 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 53.8462 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 53.8462 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 53.8462 | 5 | no |
GO:0051051 | negative regulation of transport | 46.1538 | 4 | no |
GO:0010468 | regulation of gene expression | 46.1538 | 5 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 38.4615 | 7 | no |
GO:0051174 | regulation of phosphorus metabolic process | 38.4615 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 38.4615 | 6 | no |
GO:0010038 | response to metal ion | 38.4615 | 4 | no |
GO:0051050 | positive regulation of transport | 38.4615 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 38.4615 | 7 | no |
GO:0001934 | positive regulation of protein phosphorylation | 38.4615 | 8 | no |
GO:0009892 | negative regulation of metabolic process | 38.4615 | 4 | no |
GO:0009966 | regulation of signal transduction | 38.4615 | 4 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 38.4615 | 6 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 38.4615 | 5 | no |
GO:0019220 | regulation of phosphate metabolic process | 38.4615 | 6 | no |
GO:0031399 | regulation of protein modification process | 38.4615 | 6 | no |
GO:0031401 | positive regulation of protein modification process | 38.4615 | 7 | no |
GO:0042325 | regulation of phosphorylation | 38.4615 | 7 | no |
GO:0042327 | positive regulation of phosphorylation | 38.4615 | 8 | no |
GO:0043085 | positive regulation of catalytic activity | 38.4615 | 4 | no |
GO:0043269 | regulation of ion transport | 38.4615 | 5 | no |
GO:0045859 | regulation of protein kinase activity | 30.7692 | 6 | no |
GO:0045860 | positive regulation of protein kinase activity | 30.7692 | 7 | no |
GO:0045936 | negative regulation of phosphate metabolic process | 30.7692 | 7 | no |
GO:0051046 | regulation of secretion | 30.7692 | 5 | no |
GO:0051128 | regulation of cellular component organization | 30.7692 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 30.7692 | 5 | no |
GO:0051248 | negative regulation of protein metabolic process | 30.7692 | 6 | no |
GO:0051336 | regulation of hydrolase activity | 30.7692 | 4 | no |
GO:0051338 | regulation of transferase activity | 30.7692 | 4 | no |
GO:0051345 | positive regulation of hydrolase activity | 30.7692 | 5 | no |
GO:0051347 | positive regulation of transferase activity | 30.7692 | 5 | no |
GO:0051726 | regulation of cell cycle | 30.7692 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 30.7692 | 5 | no |
GO:1903530 | regulation of secretion by cell | 30.7692 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 30.7692 | 4 | no |
GO:0030030 | cell projection organization | 30.7692 | 4 | no |
GO:0030334 | regulation of cell migration | 30.7692 | 5 | no |
GO:0031175 | neuron projection development | 30.7692 | 6 | no |
GO:0031326 | regulation of cellular biosynthetic process | 30.7692 | 5 | no |
GO:0050804 | modulation of chemical synaptic transmission | 30.7692 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 30.7692 | 4 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 30.7692 | 5 | no |
GO:2000145 | regulation of cell motility | 30.7692 | 4 | no |
GO:0001933 | negative regulation of protein phosphorylation | 30.7692 | 8 | no |
GO:0010563 | negative regulation of phosphorus metabolic process | 30.7692 | 6 | no |
GO:0031324 | negative regulation of cellular metabolic process | 30.7692 | 5 | no |
GO:0031400 | negative regulation of protein modification process | 30.7692 | 7 | no |
GO:0033674 | positive regulation of kinase activity | 30.7692 | 6 | no |
GO:0042326 | negative regulation of phosphorylation | 30.7692 | 8 | no |
GO:0043270 | positive regulation of ion transport | 30.7692 | 5 | no |
GO:0043271 | negative regulation of ion transport | 30.7692 | 5 | no |
GO:0043549 | regulation of kinase activity | 30.7692 | 5 | no |
GO:0044772 | mitotic cell cycle phase transition | 23.0769 | 4 | no |
GO:0044839 | cell cycle G2/M phase transition | 23.0769 | 4 | no |
GO:0050848 | regulation of calcium-mediated signaling | 23.0769 | 6 | no |
GO:0051099 | positive regulation of binding | 23.0769 | 4 | no |
GO:0051101 | regulation of DNA binding | 23.0769 | 4 | no |
GO:0051279 | regulation of release of sequestered calcium ion into cytosol | 23.0769 | 5 | no |
GO:0051280 | negative regulation of release of sequestered calcium ion into cytosol | 23.0769 | 6 | no |
GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol | 23.0769 | 6 | no |
GO:0051282 | regulation of sequestering of calcium ion | 23.0769 | 4 | no |
GO:0051284 | positive regulation of sequestering of calcium ion | 23.0769 | 5 | no |
GO:0051302 | regulation of cell division | 23.0769 | 4 | no |
GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity | 23.0769 | 5 | no |
GO:0051343 | positive regulation of cyclic-nucleotide phosphodiesterase activity | 23.0769 | 6 | no |
GO:0051592 | response to calcium ion | 23.0769 | 5 | no |
GO:0051924 | regulation of calcium ion transport | 23.0769 | 7 | no |
GO:0051926 | negative regulation of calcium ion transport | 23.0769 | 6 | no |
GO:0051928 | positive regulation of calcium ion transport | 23.0769 | 6 | no |
GO:0055117 | regulation of cardiac muscle contraction | 23.0769 | 7 | no |
GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity | 23.0769 | 6 | no |
GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity | 23.0769 | 7 | no |
GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity | 23.0769 | 7 | no |
GO:0061024 | membrane organization | 23.0769 | 4 | no |
GO:0071900 | regulation of protein serine/threonine kinase activity | 23.0769 | 7 | no |
GO:0071902 | positive regulation of protein serine/threonine kinase activity | 23.0769 | 8 | no |
GO:0090257 | regulation of muscle system process | 23.0769 | 5 | no |
GO:1901019 | regulation of calcium ion transmembrane transporter activity | 23.0769 | 6 | no |
GO:1901020 | negative regulation of calcium ion transmembrane transporter activity | 23.0769 | 6 | no |
GO:1901021 | positive regulation of calcium ion transmembrane transporter activity | 23.0769 | 6 | no |
GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction | 23.0769 | 6 | no |
GO:1903169 | regulation of calcium ion transmembrane transport | 23.0769 | 7 | no |
GO:1903170 | negative regulation of calcium ion transmembrane transport | 23.0769 | 7 | no |
GO:1903522 | regulation of blood circulation | 23.0769 | 5 | no |
GO:1904062 | regulation of cation transmembrane transport | 23.0769 | 6 | no |
GO:1904063 | negative regulation of cation transmembrane transport | 23.0769 | 7 | no |
GO:1904064 | positive regulation of cation transmembrane transport | 23.0769 | 7 | no |
GO:1904427 | positive regulation of calcium ion transmembrane transport | 23.0769 | 7 | no |
GO:1905912 | regulation of calcium ion export across plasma membrane | 23.0769 | 8 | no |
GO:1905913 | negative regulation of calcium ion export across plasma membrane | 23.0769 | 8 | no |
GO:2001257 | regulation of cation channel activity | 23.0769 | 6 | no |
GO:2001258 | negative regulation of cation channel activity | 23.0769 | 6 | no |
GO:2001259 | positive regulation of cation channel activity | 23.0769 | 6 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 23.0769 | 4 | no |
GO:0031344 | regulation of cell projection organization | 23.0769 | 5 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 23.0769 | 6 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.0769 | 5 | no |
GO:0051252 | regulation of RNA metabolic process | 23.0769 | 5 | no |
GO:0010243 | response to organonitrogen compound | 23.0769 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 23.0769 | 5 | no |
GO:0014070 | response to organic cyclic compound | 23.0769 | 4 | no |
GO:0022607 | cellular component assembly | 23.0769 | 4 | no |
GO:0032880 | regulation of protein localization | 23.0769 | 5 | no |
GO:0060341 | regulation of cellular localization | 23.0769 | 4 | no |
GO:0000086 | G2/M transition of mitotic cell cycle | 23.0769 | 5 | no |
GO:0005513 | detection of calcium ion | 23.0769 | 4 | no |
GO:0006937 | regulation of muscle contraction | 23.0769 | 6 | no |
GO:0006942 | regulation of striated muscle contraction | 23.0769 | 7 | no |
GO:0006996 | organelle organization | 23.0769 | 4 | no |
GO:0008016 | regulation of heart contraction | 23.0769 | 6 | no |
GO:0010564 | regulation of cell cycle process | 23.0769 | 5 | no |
GO:0010649 | regulation of cell communication by electrical coupling | 23.0769 | 5 | no |
GO:0010799 | regulation of peptidyl-threonine phosphorylation | 23.0769 | 8 | no |
GO:0010800 | positive regulation of peptidyl-threonine phosphorylation | 23.0769 | 9 | no |
GO:0010801 | negative regulation of peptidyl-threonine phosphorylation | 23.0769 | 9 | no |
GO:0010880 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 23.0769 | 6 | no |
GO:0010881 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | 23.0769 | 7 | no |
GO:0010882 | regulation of cardiac muscle contraction by calcium ion signaling | 23.0769 | 6 | no |
GO:0010921 | regulation of phosphatase activity | 23.0769 | 5 | no |
GO:0010922 | positive regulation of phosphatase activity | 23.0769 | 6 | no |
GO:0010959 | regulation of metal ion transport | 23.0769 | 6 | no |
GO:0019722 | calcium-mediated signaling | 23.0769 | 5 | no |
GO:0019932 | second-messenger-mediated signaling | 23.0769 | 4 | no |
GO:0021762 | substantia nigra development | 23.0769 | 4 | no |
GO:0022898 | regulation of transmembrane transporter activity | 23.0769 | 4 | no |
GO:0031952 | regulation of protein autophosphorylation | 23.0769 | 8 | no |
GO:0031954 | positive regulation of protein autophosphorylation | 23.0769 | 9 | no |
GO:0032410 | negative regulation of transporter activity | 23.0769 | 4 | no |
GO:0032411 | positive regulation of transporter activity | 23.0769 | 4 | no |
GO:0032412 | regulation of ion transmembrane transporter activity | 23.0769 | 5 | no |
GO:0032413 | negative regulation of ion transmembrane transporter activity | 23.0769 | 5 | no |
GO:0032414 | positive regulation of ion transmembrane transporter activity | 23.0769 | 5 | no |
GO:0032465 | regulation of cytokinesis | 23.0769 | 5 | no |
GO:0032516 | positive regulation of phosphoprotein phosphatase activity | 23.0769 | 7 | no |
GO:0034762 | regulation of transmembrane transport | 23.0769 | 4 | no |
GO:0034763 | negative regulation of transmembrane transport | 23.0769 | 5 | no |
GO:0034764 | positive regulation of transmembrane transport | 23.0769 | 5 | no |
GO:0034765 | regulation of ion transmembrane transport | 23.0769 | 5 | no |
GO:0034766 | negative regulation of ion transmembrane transport | 23.0769 | 6 | no |
GO:0034767 | positive regulation of ion transmembrane transport | 23.0769 | 6 | no |
GO:0035303 | regulation of dephosphorylation | 23.0769 | 7 | no |
GO:0035304 | regulation of protein dephosphorylation | 23.0769 | 7 | no |
GO:0035306 | positive regulation of dephosphorylation | 23.0769 | 8 | no |
GO:0035307 | positive regulation of protein dephosphorylation | 23.0769 | 8 | no |
GO:0043388 | positive regulation of DNA binding | 23.0769 | 5 | no |
GO:0043666 | regulation of phosphoprotein phosphatase activity | 23.0769 | 6 | no |
GO:0044057 | regulation of system process | 23.0769 | 4 | no |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in PPR29_HUMAN |
---|---|---|---|---|
DOID:0050700 | cardiomyopathy | 15.3846 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 15.3846 | 5 | no |
DOID:114 | heart disease | 15.3846 | 3 | no |
DOID:2843 | long QT syndrome | 15.3846 | 6 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
GRM7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GRM4_HUMAN | [view interactions] | Low throughput | no | no |
GRM8_HUMAN | [view interactions] | Low throughput | no | no |
SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
INSI2_HUMAN | [view interactions] | High throughput | no | yes |
DX39A_HUMAN | [view interactions] | High throughput | no | yes |
TBCD1_HUMAN | [view interactions] | High throughput | no | no |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBB1_HUMAN | [view interactions] | High throughput | no | yes |
KCMF1_HUMAN | [view interactions] | High throughput | no | yes |
CTSL2_HUMAN | [view interactions] | High throughput | no | no |
DPP9_HUMAN | [view interactions] | High throughput | no | yes |
TBCD4_HUMAN | [view interactions] | High throughput | no | yes |
ACD11_HUMAN | [view interactions] | High throughput | no | yes |
ELFN1_HUMAN | [view interactions] | High throughput | no | no |
DEFM_HUMAN | [view interactions] | High throughput | no | yes |
UBR4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFIP4_HUMAN | [view interactions] | High throughput | no | yes |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOH_HUMAN | [view interactions] | High throughput | no | yes |
UNC79_HUMAN | [view interactions] | High throughput | no | no |
CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |