CPNE5_HUMAN
Evidence for PS localization
Functions
Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes . Plays a role in dendrite formation by melanocytes (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CPNE5_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 38.4615 | 4 | yes |
| GO:0046872 | metal ion binding | 38.4615 | 5 | yes |
| GO:0019900 | kinase binding | 30.7692 | 4 | no |
| GO:0019901 | protein kinase binding | 23.0769 | 5 | no |
| GO:0008270 | zinc ion binding | 23.0769 | 7 | no |
| GO:0046914 | transition metal ion binding | 23.0769 | 6 | no |
| GO:0003779 | actin binding | 23.0769 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CPNE5_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 61.5385 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 46.1538 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 38.4615 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 38.4615 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 38.4615 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 30.7692 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 30.7692 | 4 | no |
| GO:0009966 | regulation of signal transduction | 30.7692 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.7692 | 5 | no |
| GO:0010646 | regulation of cell communication | 30.7692 | 4 | no |
| GO:0022607 | cellular component assembly | 30.7692 | 4 | no |
| GO:0031399 | regulation of protein modification process | 30.7692 | 6 | no |
| GO:0043933 | protein-containing complex organization | 30.7692 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 30.7692 | 5 | no |
| GO:0008104 | protein localization | 30.7692 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.0769 | 7 | no |
| GO:0009889 | regulation of biosynthetic process | 23.0769 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 23.0769 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 23.0769 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 23.0769 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.0769 | 6 | no |
| GO:0023057 | negative regulation of signaling | 23.0769 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.0769 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 23.0769 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 23.0769 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 23.0769 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 23.0769 | 7 | no |
| GO:0048585 | negative regulation of response to stimulus | 23.0769 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.0769 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.0769 | 6 | no |
| GO:0065003 | protein-containing complex assembly | 23.0769 | 5 | no |
| GO:0097435 | supramolecular fiber organization | 23.0769 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 23.0769 | 5 | no |
| GO:1902532 | negative regulation of intracellular signal transduction | 23.0769 | 6 | no |
| GO:0032446 | protein modification by small protein conjugation | 23.0769 | 7 | no |
| GO:0036211 | protein modification process | 23.0769 | 4 | no |
| GO:0043412 | macromolecule modification | 23.0769 | 4 | no |
| GO:0043687 | post-translational protein modification | 23.0769 | 5 | no |
| GO:0070647 | protein modification by small protein conjugation or removal | 23.0769 | 6 | no |
| GO:0006886 | intracellular protein transport | 23.0769 | 4 | no |
| GO:0015031 | protein transport | 23.0769 | 4 | no |
| GO:0061024 | membrane organization | 23.0769 | 4 | no |
| GO:0071702 | organic substance transport | 23.0769 | 4 | no |
| GO:0071705 | nitrogen compound transport | 23.0769 | 4 | no |
| GO:0001558 | regulation of cell growth | 15.3846 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 15.3846 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| WDHD1_HUMAN | [view interactions] | High throughput | no | no |
| MTA2_HUMAN | [view interactions] | High throughput | no | yes |
| DCUP_HUMAN | [view interactions] | High throughput | no | no |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| UTRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANR52_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI5_HUMAN | [view interactions] | High throughput | no | yes |
| P66B_HUMAN | [view interactions] | High throughput | no | yes |
| SNAG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCC1_HUMAN | [view interactions] | High throughput | no | yes |
| F1142_HUMAN | [view interactions] | High throughput | no | yes |
| SAE2_HUMAN | [view interactions] | High throughput | no | yes |
| SATB2_HUMAN | [view interactions] | High throughput | no | yes |
| SNX9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RA54B_HUMAN | [view interactions] | High throughput | no | yes |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| DSCAM_HUMAN | [view interactions] | High throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FSBP_HUMAN | [view interactions] | High throughput | no | yes |
| RABE2_HUMAN | [view interactions] | High throughput | no | yes |
| RABX5_HUMAN | [view interactions] | High throughput | no | no |
| MBNL3_HUMAN | [view interactions] | High throughput | no | no |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DHRS7_HUMAN | [view interactions] | High throughput | no | yes |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHD4_HUMAN | [view interactions] | High throughput | no | yes |
| MTA1_HUMAN | [view interactions] | High throughput | no | yes |
| P66A_HUMAN | [view interactions] | High throughput | no | yes |
| UBR4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| MBD3_HUMAN | [view interactions] | High throughput | no | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF6_HUMAN | [view interactions] | High throughput | no | no |
| CPNE9_HUMAN | [view interactions] | High throughput | no | no |
| EPN4_HUMAN | [view interactions] | High throughput | no | yes |
| CPNE3_HUMAN | [view interactions] | High throughput | no | yes |