PKN1_HUMAN
PKC-related serine/threonine-protein kinase involved in various processes such as regulation of the intermediate filaments of the actin cytoskeleton, cell migration, tumor cell invasion and transcription regulation. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Regulates the cytoskeletal network by phosphorylating proteins such as VIM and neurofilament proteins NEFH, NEFL and NEFM, leading to inhibit their polymerization. Phosphorylates Ser-575, Ser-637 and Ser-669 of MAPT/Tau, lowering its ability to bind to microtubules, resulting in disruption of tubulin assembly. Acts as a key coactivator of androgen receptor (AR)-dependent transcription, by being recruited to AR target genes and specifically mediating phosphorylation of Thr-11 of histone H3 (H3T11ph), a specific tag for epigenetic transcriptional activation that promotes demethylation of histone H3 Lys-9 (H3K9me) by KDM4C/JMJD2C. Phosphorylates HDAC5, HDAC7 and HDAC9, leading to impair their import in the nucleus. Phosphorylates Thr-38 of PPP1R14A, Ser-159, Ser-163 and Ser-170 of MARCKS, and GFAP. Able to phosphorylate RPS6 in vitro. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI001638 | DOC_AGCK_PIF_2 | DOC | 932 | 937 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in PKN1_HUMAN |
---|---|---|---|---|
GO:0019900 | kinase binding | 45.9459 | 4 | yes |
GO:0019901 | protein kinase binding | 45.9459 | 5 | yes |
GO:0017076 | purine nucleotide binding | 43.2432 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 43.2432 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 37.8378 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 32.4324 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 32.4324 | 5 | yes |
GO:0005524 | ATP binding | 27.0270 | 5 | yes |
GO:0004674 | protein serine/threonine kinase activity | 21.6216 | 4 | yes |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 21.6216 | 4 | yes |
GO:0016301 | kinase activity | 21.6216 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 21.6216 | 4 | yes |
GO:0106310 | protein serine kinase activity | 21.6216 | 4 | yes |
GO:0046872 | metal ion binding | 21.6216 | 4 | no |
GO:0005080 | protein kinase C binding | 13.5135 | 6 | yes |
GO:0042826 | histone deacetylase binding | 13.5135 | 4 | yes |
GO:0004697 | protein kinase C activity | 10.8108 | 5 | yes |
GO:0004698 | calcium-dependent protein kinase C activity | 10.8108 | 6 | yes |
GO:0009931 | calcium-dependent protein serine/threonine kinase activity | 10.8108 | 5 | yes |
GO:0010857 | calcium-dependent protein kinase activity | 10.8108 | 4 | yes |
GO:0030374 | nuclear receptor coactivator activity | 10.8108 | 4 | yes |
GO:0051020 | GTPase binding | 10.8108 | 4 | yes |
GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding | 10.8108 | 5 | yes |
GO:0140297 | DNA-binding transcription factor binding | 10.8108 | 4 | yes |
GO:0016922 | nuclear receptor binding | 8.1081 | 6 | yes |
GO:0031267 | small GTPase binding | 8.1081 | 5 | yes |
GO:0035173 | histone kinase activity | 8.1081 | 4 | yes |
GO:0035184 | histone threonine kinase activity | 8.1081 | 5 | yes |
GO:0050681 | nuclear androgen receptor binding | 8.1081 | 7 | yes |
GO:0035402 | histone kinase activity (H3-T11 specific) | 5.4054 | 6 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in PKN1_HUMAN |
---|---|---|---|---|
GO:0060255 | regulation of macromolecule metabolic process | 75.6757 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 72.9730 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 72.9730 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 67.5676 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 67.5676 | 5 | yes |
GO:0031323 | regulation of cellular metabolic process | 64.8649 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 62.1622 | 4 | no |
GO:0010646 | regulation of cell communication | 59.4595 | 4 | yes |
GO:0009966 | regulation of signal transduction | 54.0541 | 4 | yes |
GO:0031399 | regulation of protein modification process | 51.3514 | 6 | yes |
GO:0009892 | negative regulation of metabolic process | 48.6486 | 4 | yes |
GO:0010468 | regulation of gene expression | 48.6486 | 5 | yes |
GO:0009893 | positive regulation of metabolic process | 48.6486 | 4 | no |
GO:0006996 | organelle organization | 45.9459 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 45.9459 | 6 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 45.9459 | 5 | yes |
GO:0051128 | regulation of cellular component organization | 45.9459 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 43.2432 | 6 | no |
GO:0031325 | positive regulation of cellular metabolic process | 43.2432 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 43.2432 | 5 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 43.2432 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 43.2432 | 5 | no |
GO:0042325 | regulation of phosphorylation | 40.5405 | 7 | yes |
GO:0051049 | regulation of transport | 37.8378 | 4 | no |
GO:0051240 | positive regulation of multicellular organismal process | 37.8378 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 37.8378 | 7 | yes |
GO:0009889 | regulation of biosynthetic process | 37.8378 | 4 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 37.8378 | 5 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 37.8378 | 5 | yes |
GO:0036211 | protein modification process | 37.8378 | 4 | yes |
GO:0043412 | macromolecule modification | 37.8378 | 4 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 37.8378 | 5 | yes |
GO:0022607 | cellular component assembly | 35.1351 | 4 | no |
GO:0051094 | positive regulation of developmental process | 35.1351 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 35.1351 | 5 | no |
GO:0007010 | cytoskeleton organization | 35.1351 | 5 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 35.1351 | 5 | yes |
GO:0060341 | regulation of cellular localization | 32.4324 | 4 | no |
GO:0010941 | regulation of cell death | 32.4324 | 4 | no |
GO:0071310 | cellular response to organic substance | 32.4324 | 4 | no |
GO:0009967 | positive regulation of signal transduction | 32.4324 | 5 | no |
GO:0010647 | positive regulation of cell communication | 32.4324 | 5 | no |
GO:0023056 | positive regulation of signaling | 32.4324 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 32.4324 | 4 | no |
GO:0006796 | phosphate-containing compound metabolic process | 32.4324 | 4 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 32.4324 | 4 | yes |
GO:0043549 | regulation of kinase activity | 32.4324 | 5 | yes |
GO:0051248 | negative regulation of protein metabolic process | 32.4324 | 6 | yes |
GO:0051338 | regulation of transferase activity | 32.4324 | 4 | yes |
GO:0009894 | regulation of catabolic process | 32.4324 | 4 | no |
GO:0030030 | cell projection organization | 32.4324 | 4 | no |
GO:0031401 | positive regulation of protein modification process | 32.4324 | 7 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 29.7297 | 6 | no |
GO:0097435 | supramolecular fiber organization | 29.7297 | 4 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 29.7297 | 6 | no |
GO:0042981 | regulation of apoptotic process | 29.7297 | 6 | no |
GO:0043067 | regulation of programmed cell death | 29.7297 | 5 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 29.7297 | 7 | no |
GO:1901701 | cellular response to oxygen-containing compound | 29.7297 | 4 | no |
GO:2000026 | regulation of multicellular organismal development | 29.7297 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 29.7297 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.7297 | 5 | yes |
GO:0045859 | regulation of protein kinase activity | 29.7297 | 6 | yes |
GO:0031344 | regulation of cell projection organization | 29.7297 | 5 | no |
GO:0033043 | regulation of organelle organization | 29.7297 | 5 | no |
GO:0008104 | protein localization | 27.0270 | 4 | no |
GO:0010243 | response to organonitrogen compound | 27.0270 | 4 | no |
GO:0010648 | negative regulation of cell communication | 27.0270 | 5 | no |
GO:0023057 | negative regulation of signaling | 27.0270 | 4 | no |
GO:0042327 | positive regulation of phosphorylation | 27.0270 | 8 | no |
GO:0045595 | regulation of cell differentiation | 27.0270 | 4 | no |
GO:2000145 | regulation of cell motility | 27.0270 | 4 | yes |
GO:0032880 | regulation of protein localization | 27.0270 | 5 | no |
GO:0001934 | positive regulation of protein phosphorylation | 24.3243 | 8 | no |
GO:0015031 | protein transport | 24.3243 | 4 | no |
GO:0031329 | regulation of cellular catabolic process | 24.3243 | 5 | no |
GO:0043085 | positive regulation of catalytic activity | 24.3243 | 4 | no |
GO:0043269 | regulation of ion transport | 24.3243 | 5 | no |
GO:0045597 | positive regulation of cell differentiation | 24.3243 | 5 | no |
GO:0051050 | positive regulation of transport | 24.3243 | 4 | no |
GO:0071702 | organic substance transport | 24.3243 | 4 | no |
GO:0071705 | nitrogen compound transport | 24.3243 | 4 | no |
GO:0043933 | protein-containing complex organization | 24.3243 | 4 | no |
GO:0050804 | modulation of chemical synaptic transmission | 24.3243 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 24.3243 | 4 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 24.3243 | 6 | no |
GO:0006468 | protein phosphorylation | 24.3243 | 5 | yes |
GO:0016310 | phosphorylation | 24.3243 | 5 | yes |
GO:0031400 | negative regulation of protein modification process | 24.3243 | 7 | yes |
GO:0051252 | regulation of RNA metabolic process | 24.3243 | 5 | yes |
GO:0051493 | regulation of cytoskeleton organization | 21.6216 | 6 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 21.6216 | 5 | no |
GO:0002684 | positive regulation of immune system process | 21.6216 | 4 | no |
GO:0009891 | positive regulation of biosynthetic process | 21.6216 | 5 | no |
GO:0009968 | negative regulation of signal transduction | 21.6216 | 5 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.6216 | 6 | no |
GO:0010959 | regulation of metal ion transport | 21.6216 | 6 | no |
GO:0030162 | regulation of proteolysis | 21.6216 | 6 | no |
GO:0030334 | regulation of cell migration | 21.6216 | 5 | no |
GO:0030335 | positive regulation of cell migration | 21.6216 | 6 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 21.6216 | 6 | no |
GO:0033674 | positive regulation of kinase activity | 21.6216 | 6 | no |
GO:0034762 | regulation of transmembrane transport | 21.6216 | 4 | no |
GO:0040017 | positive regulation of locomotion | 21.6216 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 21.6216 | 4 | no |
GO:0051129 | negative regulation of cellular component organization | 21.6216 | 5 | no |
GO:0051347 | positive regulation of transferase activity | 21.6216 | 5 | no |
GO:2000147 | positive regulation of cell motility | 21.6216 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 21.6216 | 4 | no |
GO:0065003 | protein-containing complex assembly | 21.6216 | 5 | no |
GO:0014070 | response to organic cyclic compound | 21.6216 | 4 | no |
GO:0006355 | regulation of DNA-templated transcription | 21.6216 | 6 | yes |
GO:0010563 | negative regulation of phosphorus metabolic process | 21.6216 | 6 | yes |
GO:0043086 | negative regulation of catalytic activity | 21.6216 | 4 | yes |
GO:0045936 | negative regulation of phosphate metabolic process | 21.6216 | 7 | yes |
GO:0050776 | regulation of immune response | 21.6216 | 4 | yes |
GO:1903506 | regulation of nucleic acid-templated transcription | 21.6216 | 7 | yes |
GO:2001141 | regulation of RNA biosynthetic process | 21.6216 | 6 | yes |
GO:0010975 | regulation of neuron projection development | 21.6216 | 7 | no |
GO:0006357 | regulation of transcription by RNA polymerase II | 18.9189 | 7 | yes |
GO:0006915 | apoptotic process | 18.9189 | 4 | yes |
GO:0033673 | negative regulation of kinase activity | 18.9189 | 6 | yes |
GO:0042127 | regulation of cell population proliferation | 18.9189 | 4 | yes |
GO:0042326 | negative regulation of phosphorylation | 18.9189 | 8 | yes |
GO:0051348 | negative regulation of transferase activity | 18.9189 | 5 | yes |
GO:0001933 | negative regulation of protein phosphorylation | 16.2162 | 8 | yes |
GO:0006469 | negative regulation of protein kinase activity | 16.2162 | 7 | yes |
GO:0018105 | peptidyl-serine phosphorylation | 16.2162 | 6 | yes |
GO:0018193 | peptidyl-amino acid modification | 16.2162 | 5 | yes |
GO:0018209 | peptidyl-serine modification | 16.2162 | 6 | yes |
GO:0050865 | regulation of cell activation | 16.2162 | 4 | yes |
GO:0002694 | regulation of leukocyte activation | 13.5135 | 4 | yes |
GO:0001667 | ameboidal-type cell migration | 10.8108 | 4 | yes |
GO:0008285 | negative regulation of cell population proliferation | 10.8108 | 5 | yes |
GO:0010631 | epithelial cell migration | 10.8108 | 5 | yes |
GO:0051249 | regulation of lymphocyte activation | 10.8108 | 5 | yes |
GO:0002683 | negative regulation of immune system process | 8.1081 | 4 | yes |
GO:0002697 | regulation of immune effector process | 8.1081 | 4 | yes |
GO:0006325 | chromatin organization | 8.1081 | 4 | yes |
GO:0006972 | hyperosmotic response | 8.1081 | 4 | yes |
GO:0033143 | regulation of intracellular steroid hormone receptor signaling pathway | 8.1081 | 5 | yes |
GO:0070227 | lymphocyte apoptotic process | 8.1081 | 6 | yes |
GO:0071887 | leukocyte apoptotic process | 8.1081 | 5 | yes |
GO:0001782 | B cell homeostasis | 5.4054 | 4 | yes |
GO:0001783 | B cell apoptotic process | 5.4054 | 7 | yes |
GO:0002634 | regulation of germinal center formation | 5.4054 | 5 | yes |
GO:0002637 | regulation of immunoglobulin production | 5.4054 | 6 | yes |
GO:0002695 | negative regulation of leukocyte activation | 5.4054 | 5 | yes |
GO:0002700 | regulation of production of molecular mediator of immune response | 5.4054 | 5 | yes |
GO:0002819 | regulation of adaptive immune response | 5.4054 | 5 | yes |
GO:0002822 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 5.4054 | 6 | yes |
GO:0030888 | regulation of B cell proliferation | 5.4054 | 7 | yes |
GO:0030889 | negative regulation of B cell proliferation | 5.4054 | 8 | yes |
GO:0032944 | regulation of mononuclear cell proliferation | 5.4054 | 6 | yes |
GO:0032945 | negative regulation of mononuclear cell proliferation | 5.4054 | 7 | yes |
GO:0048534 | hematopoietic or lymphoid organ development | 5.4054 | 4 | yes |
GO:0048536 | spleen development | 5.4054 | 5 | yes |
GO:0048872 | homeostasis of number of cells | 5.4054 | 4 | yes |
GO:0050670 | regulation of lymphocyte proliferation | 5.4054 | 6 | yes |
GO:0050672 | negative regulation of lymphocyte proliferation | 5.4054 | 7 | yes |
GO:0050864 | regulation of B cell activation | 5.4054 | 6 | yes |
GO:0050866 | negative regulation of cell activation | 5.4054 | 5 | yes |
GO:0050869 | negative regulation of B cell activation | 5.4054 | 7 | yes |
GO:0051250 | negative regulation of lymphocyte activation | 5.4054 | 6 | yes |
GO:0060765 | regulation of androgen receptor signaling pathway | 5.4054 | 6 | yes |
GO:0070663 | regulation of leukocyte proliferation | 5.4054 | 5 | yes |
GO:0070664 | negative regulation of leukocyte proliferation | 5.4054 | 6 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MK14_HUMAN | [view interactions] | Low throughput | no | yes |
MK12_HUMAN | [view interactions] | Low throughput | no | no |
MP2K3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MP2K6_HUMAN | [view interactions] | Low throughput | no | yes |
M3K20_HUMAN | [view interactions] | Low throughput | no | yes |
KDM1A_HUMAN | [view interactions] | Low throughput | no | yes |
AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RHOA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VIME_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CDR2_HUMAN | [view interactions] | Low throughput | no | yes |
NFL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF1_HUMAN | [view interactions] | Low throughput | no | no |
PDPK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NFH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDF2_HUMAN | [view interactions] | Low throughput | no | no |
AKAP9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CCNT2_HUMAN | [view interactions] | Low throughput | no | yes |
ACTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PLD1_HUMAN | [view interactions] | Low throughput | no | no |
PDK1_HUMAN | [view interactions] | Low throughput | no | yes |
TBA1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TBB5_HUMAN | [view interactions] | Low throughput | no | yes |
ZFAN6_HUMAN | [view interactions] | Low throughput | no | yes |
TNR1B_HUMAN | [view interactions] | Low throughput | no | no |
MK11_HUMAN | [view interactions] | Low throughput | no | yes |
MPIP3_HUMAN | [view interactions] | Low throughput | no | yes |
HDAC5_HUMAN | [view interactions] | Low throughput | no | yes |
H32_HUMAN | [view interactions] | Low throughput | no | yes |
PKN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CASP3_HUMAN | [view interactions] | Low throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MARCS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
WDR5_HUMAN | [view interactions] | Low throughput | no | no |
KMT2A_HUMAN | [view interactions] | Low throughput | no | yes |
RBBP5_HUMAN | [view interactions] | Low throughput | no | yes |
ASH2L_HUMAN | [view interactions] | Low throughput | no | yes |
HOME3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BUD23_HUMAN | [view interactions] | High throughput | no | yes |
SPR2D_HUMAN | [view interactions] | High throughput | no | no |
ZN282_HUMAN | [view interactions] | High throughput | no | yes |
CC85B_HUMAN | [view interactions] | High throughput | no | yes |
APBB1_HUMAN | [view interactions] | High throughput | no | yes |
GAB2_HUMAN | [view interactions] | High throughput | no | yes |
RASA1_HUMAN | [view interactions] | High throughput | no | yes |
STA5B_HUMAN | [view interactions] | High throughput | no | yes |
PHAG1_HUMAN | [view interactions] | High throughput | no | yes |
SLIK6_HUMAN | [view interactions] | High throughput | no | yes |
SHC2_HUMAN | [view interactions] | High throughput | no | yes |
SYDE1_HUMAN | [view interactions] | High throughput | no | yes |
TNS2_HUMAN | [view interactions] | High throughput | no | no |
MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TRI18_HUMAN | [view interactions] | High throughput | no | no |
K1C15_HUMAN | [view interactions] | High throughput | no | no |
GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
K1H1_HUMAN | [view interactions] | High throughput | no | no |
ADIP_HUMAN | [view interactions] | High throughput | no | yes |
SRTD3_HUMAN | [view interactions] | High throughput | no | no |
IKZF3_HUMAN | [view interactions] | High throughput | no | no |
K1328_HUMAN | [view interactions] | High throughput | no | yes |
CRTP1_HUMAN | [view interactions] | High throughput | no | yes |
AKP8L_HUMAN | [view interactions] | High throughput | no | yes |
ARSA_HUMAN | [view interactions] | High throughput | no | yes |
STMN3_HUMAN | [view interactions] | High throughput | no | yes |
ZFP90_HUMAN | [view interactions] | High throughput | no | no |
DYDC1_HUMAN | [view interactions] | High throughput | no | no |
PNMA1_HUMAN | [view interactions] | High throughput | no | yes |
MIPO1_HUMAN | [view interactions] | High throughput | no | yes |
STX11_HUMAN | [view interactions] | High throughput | no | yes |
KRT35_HUMAN | [view interactions] | High throughput | no | no |
KRT34_HUMAN | [view interactions] | High throughput | no | no |
K1C16_HUMAN | [view interactions] | High throughput | no | no |
HSF2B_HUMAN | [view interactions] | High throughput | no | yes |
TSG10_HUMAN | [view interactions] | High throughput | no | no |
KRT37_HUMAN | [view interactions] | High throughput | no | no |
USBP1_HUMAN | [view interactions] | High throughput | no | no |
PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MKRN3_HUMAN | [view interactions] | High throughput | no | yes |
SPAG5_HUMAN | [view interactions] | High throughput | no | yes |
GO45_HUMAN | [view interactions] | High throughput | no | yes |
HAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GG6L9_HUMAN | [view interactions] | High throughput | no | no |
K1C19_HUMAN | [view interactions] | High throughput | no | no |
PO6F2_HUMAN | [view interactions] | High throughput | no | no |
CEP70_HUMAN | [view interactions] | High throughput | no | yes |
ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
TRI27_HUMAN | [view interactions] | High throughput | no | yes |
CC103_HUMAN | [view interactions] | High throughput | no | no |
SYCE3_HUMAN | [view interactions] | High throughput | no | no |
PSB4_HUMAN | [view interactions] | High throughput | no | yes |
INT11_HUMAN | [view interactions] | High throughput | no | yes |
SMYD3_HUMAN | [view interactions] | High throughput | no | yes |
LRC61_HUMAN | [view interactions] | High throughput | no | yes |
HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
EIF3F_HUMAN | [view interactions] | High throughput | no | yes |
KCD17_HUMAN | [view interactions] | High throughput | no | yes |
CCNJL_HUMAN | [view interactions] | High throughput | no | yes |
THAP3_HUMAN | [view interactions] | High throughput | no | yes |
ZN581_HUMAN | [view interactions] | High throughput | no | no |
BECN1_HUMAN | [view interactions] | High throughput | no | yes |
ZN232_HUMAN | [view interactions] | High throughput | no | no |
EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CB015_HUMAN | [view interactions] | High throughput | no | no |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CE57L_HUMAN | [view interactions] | High throughput | no | yes |
UBR2_HUMAN | [view interactions] | High throughput | no | yes |
TRIM1_HUMAN | [view interactions] | High throughput | no | no |
KRT36_HUMAN | [view interactions] | High throughput | no | no |
RAB3I_HUMAN | [view interactions] | High throughput | no | no |
CC136_HUMAN | [view interactions] | High throughput | no | yes |
MTUS2_HUMAN | [view interactions] | High throughput | no | yes |
ATL4_HUMAN | [view interactions] | High throughput | no | yes |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CC138_HUMAN | [view interactions] | High throughput | no | yes |
CEP57_HUMAN | [view interactions] | High throughput | no | yes |
HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CD81_HUMAN | [view interactions] | High throughput | no | no |
PA2G4_HUMAN | [view interactions] | High throughput | no | yes |
MAGAA_HUMAN | [view interactions] | High throughput | no | no |
UPAR_HUMAN | [view interactions] | High throughput | no | yes |
RHEX_HUMAN | [view interactions] | High throughput | no | no |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
KBTB8_HUMAN | [view interactions] | High throughput | no | no |
COG6_HUMAN | [view interactions] | High throughput | no | yes |
AEN_HUMAN | [view interactions] | High throughput | no | no |
FUCM_HUMAN | [view interactions] | High throughput | no | yes |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
GLUC_HUMAN | [view interactions] | High throughput | no | no |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
DDX58_HUMAN | [view interactions] | High throughput | no | yes |
SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
SLIRP_HUMAN | [view interactions] | High throughput | no | yes |
CERS6_HUMAN | [view interactions] | High throughput | no | yes |
S10A2_HUMAN | [view interactions] | High throughput | no | no |
INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S39A7_HUMAN | [view interactions] | High throughput | no | yes |
INHBB_HUMAN | [view interactions] | High throughput | no | no |
PLAL2_HUMAN | [view interactions] | High throughput | no | no |
FBX32_HUMAN | [view interactions] | High throughput | no | no |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PKN2_HUMAN | [view interactions] | High throughput | no | yes |
RBCC1_HUMAN | [view interactions] | High throughput | no | no |
NUP85_HUMAN | [view interactions] | High throughput | no | yes |
BRE1B_HUMAN | [view interactions] | High throughput | no | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MK09_HUMAN | [view interactions] | High throughput | no | yes |
TM1L1_HUMAN | [view interactions] | High throughput | no | yes |
PPM1A_HUMAN | [view interactions] | High throughput | no | yes |
PPM1G_HUMAN | [view interactions] | High throughput | no | no |
RHG05_HUMAN | [view interactions] | Computational | no | yes |
CDK1_HUMAN | [view interactions] | Computational | no | no |
RHOC_HUMAN | [view interactions] | Computational | no | no |
1433E_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KPCE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KAPCG_HUMAN | [view interactions] | Computational | no | no |
AAKG1_HUMAN | [view interactions] | Computational | no | no |
KAP3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PP1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PP14A_HUMAN | [view interactions] | Computational | no | yes |
ANDR_HUMAN | [view interactions] | Computational | no | no |
KAPCB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NCOA2_HUMAN | [view interactions] | Computational | no | no |
AKP13_HUMAN | [view interactions] | Computational | no | yes |
KAP2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
2A5D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MEFV_HUMAN | [view interactions] | Computational | no | no |
KLK2_HUMAN | [view interactions] | Computational | no | no |
KLK3_HUMAN | [view interactions] | Computational | no | no |
PKN3_HUMAN | [view interactions] | Computational | no | yes |