CLIP3_HUMAN
Evidence for PS localization
Functions
Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes. [View more on UniProt]
Protein features
Transmembrane
Phase separation
ELM
Phosphorylation
PFAM
Coiled coil
Anchor
Disordered
Interacting regions
Sequence
LOADING 91%
![](/static/images/legend1.gif)
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
![](/static/images/legend2.gif)
Network
Isoforms
LOADING 80%
![](/static/images/legend3.gif)
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in CLIP3_HUMAN |
---|---|---|---|---|
GO:0019900 | kinase binding | 40.0000 | 4 | no |
GO:0019901 | protein kinase binding | 40.0000 | 5 | no |
GO:0008017 | microtubule binding | 30.0000 | 5 | yes |
GO:0015631 | tubulin binding | 30.0000 | 4 | yes |
GO:0043169 | cation binding | 30.0000 | 4 | no |
GO:0046872 | metal ion binding | 30.0000 | 5 | no |
GO:0003723 | RNA binding | 30.0000 | 4 | no |
GO:0042803 | protein homodimerization activity | 30.0000 | 4 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in CLIP3_HUMAN |
---|---|---|---|---|
GO:0031323 | regulation of cellular metabolic process | 100.0000 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 100.0000 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 90.0000 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 90.0000 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 90.0000 | 5 | no |
GO:0048522 | positive regulation of cellular process | 90.0000 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 90.0000 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 90.0000 | 4 | yes |
GO:0010468 | regulation of gene expression | 80.0000 | 6 | no |
GO:0009893 | positive regulation of metabolic process | 80.0000 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 80.0000 | 5 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 70.0000 | 5 | yes |
GO:0051246 | regulation of protein metabolic process | 70.0000 | 5 | yes |
GO:0071702 | organic substance transport | 70.0000 | 4 | yes |
GO:0009891 | positive regulation of biosynthetic process | 60.0000 | 5 | no |
GO:0009894 | regulation of catabolic process | 60.0000 | 4 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 60.0000 | 6 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 60.0000 | 6 | no |
GO:0009892 | negative regulation of metabolic process | 60.0000 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 60.0000 | 5 | no |
GO:0010646 | regulation of cell communication | 60.0000 | 4 | no |
GO:0031399 | regulation of protein modification process | 60.0000 | 6 | yes |
GO:0042981 | regulation of apoptotic process | 60.0000 | 5 | yes |
GO:0043067 | regulation of programmed cell death | 60.0000 | 4 | yes |
GO:0051049 | regulation of transport | 60.0000 | 4 | yes |
Disease
No data found.
All partners
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AKT2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CASP8_HUMAN | [view interactions] | Low throughput | no | yes |
CEP83_HUMAN | [view interactions] | High throughput | no | yes |
CYLD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FADD_HUMAN | [view interactions] | Low throughput | no | yes |
FBX7_HUMAN | [view interactions] | High throughput | no | yes |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRN_HUMAN | [view interactions] | High throughput | no | no |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RIPK1_HUMAN | [view interactions] | Low throughput | no | yes |
RNF11_HUMAN | [view interactions] | High throughput | no | yes |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SPDYA_HUMAN | [view interactions] | Low throughput | no | no |
TLE5_HUMAN | [view interactions] | High throughput | no | no |
TNR1A_HUMAN | [view interactions] | Low throughput | no | yes |
TNR21_HUMAN | [view interactions] | Low throughput | no | yes |
WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |