PRAF2_HUMAN
Evidence for PS localization
Functions
May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PRAF2_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 25.0000 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 25.0000 | 4 | no |
| GO:0046872 | metal ion binding | 25.0000 | 4 | no |
| GO:0019001 | guanyl nucleotide binding | 21.4286 | 5 | no |
| GO:0032561 | guanyl ribonucleotide binding | 21.4286 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 21.4286 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PRAF2_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 53.5714 | 4 | yes |
| GO:0015031 | protein transport | 39.2857 | 4 | yes |
| GO:0071702 | organic substance transport | 39.2857 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 39.2857 | 4 | yes |
| GO:0006996 | organelle organization | 39.2857 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 35.7143 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 32.1429 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 32.1429 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 25.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 25.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 25.0000 | 4 | no |
| GO:0006886 | intracellular protein transport | 21.4286 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 21.4286 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 21.4286 | 5 | no |
| GO:0006811 | ion transport | 10.7143 | 4 | yes |
| GO:0003333 | amino acid transmembrane transport | 7.1429 | 5 | yes |
| GO:0006820 | anion transport | 7.1429 | 5 | yes |
| GO:0006835 | dicarboxylic acid transport | 7.1429 | 7 | yes |
| GO:0006865 | amino acid transport | 7.1429 | 5 | yes |
| GO:0015711 | organic anion transport | 7.1429 | 5 | yes |
| GO:0015800 | acidic amino acid transport | 7.1429 | 6 | yes |
| GO:0015807 | L-amino acid transport | 7.1429 | 5 | yes |
| GO:0015813 | L-glutamate transmembrane transport | 7.1429 | 5 | yes |
| GO:0015849 | organic acid transport | 7.1429 | 5 | yes |
| GO:0046942 | carboxylic acid transport | 7.1429 | 6 | yes |
| GO:0051938 | L-glutamate import | 7.1429 | 6 | yes |
| GO:0098656 | anion transmembrane transport | 7.1429 | 4 | yes |
| GO:1902475 | L-alpha-amino acid transmembrane transport | 7.1429 | 6 | yes |
| GO:1905039 | carboxylic acid transmembrane transport | 7.1429 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in PRAF2_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 7.1429 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CCR5_HUMAN | [view interactions] | Low throughput | no | no |
| PRAF3_HUMAN | [view interactions] | Low throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLIN3_HUMAN | [view interactions] | Low throughput | no | yes |
| PRAF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SL7A1_HUMAN | [view interactions] | High throughput | no | no |
| DPEP1_HUMAN | [view interactions] | High throughput | no | no |
| DLK1_HUMAN | [view interactions] | High throughput | no | no |
| TSN17_HUMAN | [view interactions] | High throughput | no | yes |
| PACC1_HUMAN | [view interactions] | High throughput | no | no |
| TSN5_HUMAN | [view interactions] | High throughput | no | no |
| CGAT2_HUMAN | [view interactions] | High throughput | no | yes |
| VAC14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XRP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| REEP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS53_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHOT1_HUMAN | [view interactions] | High throughput | no | no |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| MCEM1_HUMAN | [view interactions] | High throughput | no | no |
| CLC10_HUMAN | [view interactions] | High throughput | no | yes |
| RNF5_HUMAN | [view interactions] | High throughput | no | yes |
| 3HIDH_HUMAN | [view interactions] | High throughput | no | yes |
| TMX2_HUMAN | [view interactions] | High throughput | no | yes |
| DHB11_HUMAN | [view interactions] | High throughput | no | yes |
| TLCD4_HUMAN | [view interactions] | High throughput | no | no |
| CIA2A_HUMAN | [view interactions] | High throughput | no | yes |
| CXA5_HUMAN | [view interactions] | High throughput | no | yes |
| CXA8_HUMAN | [view interactions] | High throughput | no | no |
| ZDH15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AQP6_HUMAN | [view interactions] | High throughput | no | no |
| REEP4_HUMAN | [view interactions] | High throughput | no | no |
| CD79A_HUMAN | [view interactions] | High throughput | no | no |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| SOAT_HUMAN | [view interactions] | High throughput | no | no |
| GP152_HUMAN | [view interactions] | High throughput | no | no |
| TM14B_HUMAN | [view interactions] | High throughput | no | no |
| AGR3_HUMAN | [view interactions] | High throughput | no | no |
| ABHGA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MID51_HUMAN | [view interactions] | High throughput | no | no |
| RETR3_HUMAN | [view interactions] | High throughput | no | yes |
| AGRD1_HUMAN | [view interactions] | High throughput | no | yes |
| TECT3_HUMAN | [view interactions] | High throughput | no | yes |
| TECT2_HUMAN | [view interactions] | High throughput | no | yes |
| NDRG4_HUMAN | [view interactions] | High throughput | no | no |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MINY2_HUMAN | [view interactions] | High throughput | no | no |
| TR10B_HUMAN | [view interactions] | High throughput | no | no |
| LPAR1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DUS21_HUMAN | [view interactions] | High throughput | no | no |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| DUS9_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| AAKG3_HUMAN | [view interactions] | High throughput | no | no |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T4S5_HUMAN | [view interactions] | High throughput | no | no |
| SG2A1_HUMAN | [view interactions] | High throughput | no | no |
| TSN10_HUMAN | [view interactions] | High throughput | no | no |
| TR10C_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| PDE2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCM10_HUMAN | [view interactions] | High throughput | no | no |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YIPF5_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| RPA34_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV5_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |