LPAR1_HUMAN
Evidence for PS localization
Functions
Receptor for lysophosphatidic acid (LPA) (PubMed, PubMed, PubMed, PubMed). Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents. Activates downstream signaling cascades via the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels (PubMed). Signaling triggers an increase of cytoplasmic Ca(2+) levels (PubMed, PubMed, PubMed). Activates RALA; this leads to the activation of phospholipase C (PLC) and the formation of inositol 1,4,5-trisphosphate (PubMed). Signaling mediates activation of down-stream MAP kinases . Contributes to the regulation of cell shape. Promotes Rho-dependent reorganization of the actin cytoskeleton in neuronal cells and neurite retraction (PubMed). Promotes the activation of Rho and the formation of actin stress fibers (PubMed). Promotes formation of lamellipodia at the leading edge of migrating cells via activation of RAC1 . Through its function as lysophosphatidic acid receptor, plays a role in chemotaxis and cell migration, including responses to injury and wounding (PubMed, PubMed, PubMed). Plays a role in triggering inflammation in response to bacterial lipopolysaccharide (LPS) via its interaction with CD14. Promotes cell proliferation in response to lysophosphatidic acid. Required for normal skeleton development. May play a role in osteoblast differentiation. Required for normal brain development. Required for normal proliferation, survival and maturation of newly formed neurons in the adult dentate gyrus. Plays a role in pain perception and in the initiation of neuropathic pain . [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in LPAR1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 27.4510 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 27.4510 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.4510 | 4 | no |
| GO:0003924 | GTPase activity | 23.5294 | 7 | no |
| GO:0016462 | pyrophosphatase activity | 23.5294 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 23.5294 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 23.5294 | 6 | no |
| GO:0046872 | metal ion binding | 21.5686 | 4 | no |
| GO:0004930 | G protein-coupled receptor activity | 15.6863 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in LPAR1_HUMAN |
|---|---|---|---|---|
| GO:0010646 | regulation of cell communication | 45.0980 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 45.0980 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 41.1765 | 4 | yes |
| GO:0051049 | regulation of transport | 35.2941 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 33.3333 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 31.3725 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 31.3725 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 29.4118 | 4 | no |
| GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 27.4510 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 27.4510 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 27.4510 | 4 | yes |
| GO:0043085 | positive regulation of catalytic activity | 27.4510 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 27.4510 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 27.4510 | 5 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 27.4510 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 27.4510 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 25.4902 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 25.4902 | 4 | no |
| GO:0071310 | cellular response to organic substance | 23.5294 | 4 | no |
| GO:0010468 | regulation of gene expression | 23.5294 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 23.5294 | 5 | no |
| GO:0071702 | organic substance transport | 23.5294 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 23.5294 | 5 | no |
| GO:0010941 | regulation of cell death | 23.5294 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 23.5294 | 4 | no |
| GO:0022607 | cellular component assembly | 23.5294 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 21.5686 | 5 | yes |
| GO:0008104 | protein localization | 21.5686 | 4 | no |
| GO:0032880 | regulation of protein localization | 21.5686 | 5 | no |
| GO:0051050 | positive regulation of transport | 21.5686 | 4 | no |
| GO:0043269 | regulation of ion transport | 21.5686 | 5 | no |
| GO:0006996 | organelle organization | 21.5686 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 21.5686 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 21.5686 | 5 | no |
| GO:0051336 | regulation of hydrolase activity | 19.6078 | 4 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 19.6078 | 6 | yes |
| GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 15.6863 | 5 | yes |
| GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 15.6863 | 5 | yes |
| GO:0051128 | regulation of cellular component organization | 15.6863 | 4 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 13.7255 | 5 | yes |
| GO:0043408 | regulation of MAPK cascade | 11.7647 | 6 | yes |
| GO:0051130 | positive regulation of cellular component organization | 11.7647 | 5 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 9.8039 | 4 | yes |
| GO:0043410 | positive regulation of MAPK cascade | 9.8039 | 7 | yes |
| GO:0008360 | regulation of cell shape | 7.8431 | 6 | yes |
| GO:0022604 | regulation of cell morphogenesis | 7.8431 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 7.8431 | 5 | yes |
| GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | 7.8431 | 6 | yes |
| GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 7.8431 | 7 | yes |
| GO:0051056 | regulation of small GTPase mediated signal transduction | 7.8431 | 6 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 7.8431 | 6 | yes |
| GO:0010517 | regulation of phospholipase activity | 5.8824 | 6 | yes |
| GO:0010518 | positive regulation of phospholipase activity | 5.8824 | 7 | yes |
| GO:0010975 | regulation of neuron projection development | 5.8824 | 7 | yes |
| GO:0031344 | regulation of cell projection organization | 5.8824 | 5 | yes |
| GO:0032970 | regulation of actin filament-based process | 5.8824 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 5.8824 | 4 | yes |
| GO:0046578 | regulation of Ras protein signal transduction | 5.8824 | 7 | yes |
| GO:0046579 | positive regulation of Ras protein signal transduction | 5.8824 | 8 | yes |
| GO:0051057 | positive regulation of small GTPase mediated signal transduction | 5.8824 | 7 | yes |
| GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway | 5.8824 | 4 | yes |
| GO:0060191 | regulation of lipase activity | 5.8824 | 5 | yes |
| GO:0060193 | positive regulation of lipase activity | 5.8824 | 6 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 5.8824 | 6 | yes |
| GO:0007202 | activation of phospholipase C activity | 3.9216 | 9 | yes |
| GO:0010638 | positive regulation of organelle organization | 3.9216 | 6 | yes |
| GO:0010863 | positive regulation of phospholipase C activity | 3.9216 | 8 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 3.9216 | 5 | yes |
| GO:0035023 | regulation of Rho protein signal transduction | 3.9216 | 8 | yes |
| GO:0035025 | positive regulation of Rho protein signal transduction | 3.9216 | 9 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 3.9216 | 5 | yes |
| GO:0051495 | positive regulation of cytoskeleton organization | 3.9216 | 7 | yes |
| GO:0110053 | regulation of actin filament organization | 3.9216 | 6 | yes |
| GO:1900274 | regulation of phospholipase C activity | 3.9216 | 7 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 3.9216 | 5 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 3.9216 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ARHGC_HUMAN | [view interactions] | Low throughput | no | yes |
| CAR10_HUMAN | [view interactions] | Low throughput | no | yes |
| ARHGB_HUMAN | [view interactions] | Low throughput | no | yes |
| ENPP2_HUMAN | [view interactions] | Low throughput | no | yes |
| ITB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NED4L_HUMAN | [view interactions] | Low throughput | no | yes |
| UBP11_HUMAN | [view interactions] | Low throughput | no | yes |
| CD14_HUMAN | [view interactions] | Low throughput | no | no |
| GIPC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DP13A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MRS2_HUMAN | [view interactions] | High throughput | no | no |
| REEP4_HUMAN | [view interactions] | High throughput | no | no |
| MTR1L_HUMAN | [view interactions] | High throughput | no | no |
| MFSD5_HUMAN | [view interactions] | High throughput | no | yes |
| ENPP4_HUMAN | [view interactions] | High throughput | no | yes |
| CIA30_HUMAN | [view interactions] | High throughput | no | yes |
| MAN1_HUMAN | [view interactions] | High throughput | no | yes |
| STX8_HUMAN | [view interactions] | High throughput | no | yes |
| S39AA_HUMAN | [view interactions] | High throughput | no | no |
| GPC5B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ELOV2_HUMAN | [view interactions] | High throughput | no | no |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| RMND1_HUMAN | [view interactions] | High throughput | no | yes |
| ZDH18_HUMAN | [view interactions] | High throughput | no | yes |
| SAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SERC1_HUMAN | [view interactions] | High throughput | no | yes |
| CERS4_HUMAN | [view interactions] | High throughput | no | yes |
| RN121_HUMAN | [view interactions] | High throughput | no | yes |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| XYLT2_HUMAN | [view interactions] | High throughput | no | no |
| ECSIT_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI2_HUMAN | [view interactions] | High throughput | no | yes |
| F210B_HUMAN | [view interactions] | High throughput | no | yes |
| RN170_HUMAN | [view interactions] | High throughput | no | yes |
| REEP6_HUMAN | [view interactions] | High throughput | no | no |
| CERS2_HUMAN | [view interactions] | High throughput | no | no |
| F241B_HUMAN | [view interactions] | High throughput | no | yes |
| CHP3_HUMAN | [view interactions] | High throughput | no | yes |
| TM186_HUMAN | [view interactions] | High throughput | no | no |
| PEX13_HUMAN | [view interactions] | High throughput | no | yes |
| BRI3B_HUMAN | [view interactions] | High throughput | no | yes |
| CTR3_HUMAN | [view interactions] | High throughput | no | no |
| GOGA5_HUMAN | [view interactions] | High throughput | no | yes |
| MFSD8_HUMAN | [view interactions] | High throughput | no | yes |
| TM87A_HUMAN | [view interactions] | High throughput | no | yes |
| ARL10_HUMAN | [view interactions] | High throughput | no | yes |
| F241A_HUMAN | [view interactions] | High throughput | no | yes |
| FITM2_HUMAN | [view interactions] | High throughput | no | no |
| CGAT2_HUMAN | [view interactions] | High throughput | no | yes |
| RETR3_HUMAN | [view interactions] | High throughput | no | yes |
| CERS6_HUMAN | [view interactions] | High throughput | no | yes |
| HACD2_HUMAN | [view interactions] | High throughput | no | yes |
| MBOA5_HUMAN | [view interactions] | High throughput | no | no |
| TM164_HUMAN | [view interactions] | High throughput | no | yes |
| COL12_HUMAN | [view interactions] | High throughput | no | no |
| AG10A_HUMAN | [view interactions] | High throughput | no | yes |
| ITPR2_HUMAN | [view interactions] | High throughput | no | yes |
| SCAP_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| SELT_HUMAN | [view interactions] | High throughput | no | yes |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| SL9A1_HUMAN | [view interactions] | High throughput | no | no |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| TMM11_HUMAN | [view interactions] | High throughput | no | no |
| PPAL_HUMAN | [view interactions] | High throughput | no | no |
| ATP8_HUMAN | [view interactions] | High throughput | no | no |
| NU4M_HUMAN | [view interactions] | High throughput | no | yes |
| CO1A1_HUMAN | [view interactions] | High throughput | no | yes |
| COX3_HUMAN | [view interactions] | High throughput | no | yes |
| S1PR2_HUMAN | [view interactions] | High throughput | no | no |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| ATP9A_HUMAN | [view interactions] | High throughput | no | yes |
| XYLK_HUMAN | [view interactions] | High throughput | no | yes |
| S19A2_HUMAN | [view interactions] | High throughput | no | yes |
| TSN3_HUMAN | [view interactions] | High throughput | no | yes |
| EXTL3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB5_HUMAN | [view interactions] | High throughput | no | yes |
| EMC8_HUMAN | [view interactions] | High throughput | no | no |
| MIA2_HUMAN | [view interactions] | High throughput | no | yes |
| SCAM2_HUMAN | [view interactions] | High throughput | no | no |
| T120B_HUMAN | [view interactions] | High throughput | no | yes |
| TM223_HUMAN | [view interactions] | High throughput | no | yes |
| IPPK_HUMAN | [view interactions] | High throughput | no | yes |
| C3AR_HUMAN | [view interactions] | High throughput | no | no |
| GPR21_HUMAN | [view interactions] | High throughput | no | no |
| LYPD3_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DRD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRSF6_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MBOA7_HUMAN | [view interactions] | High throughput | no | no |
| PIGO_HUMAN | [view interactions] | High throughput | no | no |
| GOGB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPC5C_HUMAN | [view interactions] | High throughput | no | no |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPAA1_HUMAN | [view interactions] | High throughput | no | yes |
| CXG1_HUMAN | [view interactions] | High throughput | no | no |
| MRP4_HUMAN | [view interactions] | High throughput | no | no |
| S35B2_HUMAN | [view interactions] | High throughput | no | no |
| SPP2B_HUMAN | [view interactions] | High throughput | no | yes |
| ZDH17_HUMAN | [view interactions] | High throughput | no | yes |
| REEP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX5_HUMAN | [view interactions] | High throughput | no | yes |
| ZNT5_HUMAN | [view interactions] | High throughput | no | yes |
| HMDH_HUMAN | [view interactions] | High throughput | no | yes |
| TM87B_HUMAN | [view interactions] | High throughput | no | yes |
| PIGU_HUMAN | [view interactions] | High throughput | no | no |
| PGAP4_HUMAN | [view interactions] | High throughput | no | no |
| ZMYM3_HUMAN | [view interactions] | High throughput | no | yes |
| S39A1_HUMAN | [view interactions] | High throughput | no | no |
| EXTL2_HUMAN | [view interactions] | High throughput | no | yes |
| NOP9_HUMAN | [view interactions] | High throughput | no | no |
| GPHRA_HUMAN | [view interactions] | High throughput | no | no |
| ALG6_HUMAN | [view interactions] | High throughput | no | no |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| SC5D_HUMAN | [view interactions] | High throughput | no | yes |
| NU1M_HUMAN | [view interactions] | High throughput | no | yes |
| CD47_HUMAN | [view interactions] | High throughput | no | no |
| ZDHC9_HUMAN | [view interactions] | High throughput | no | yes |
| UQCC1_HUMAN | [view interactions] | High throughput | no | yes |
| LNP_HUMAN | [view interactions] | High throughput | no | yes |
| RTN2_HUMAN | [view interactions] | High throughput | no | no |
| B4GT3_HUMAN | [view interactions] | High throughput | no | yes |
| TMPPE_HUMAN | [view interactions] | High throughput | no | yes |
| NDC1_HUMAN | [view interactions] | High throughput | no | yes |
| ZNT7_HUMAN | [view interactions] | High throughput | no | no |
| AGRE5_HUMAN | [view interactions] | High throughput | no | no |
| ENTP7_HUMAN | [view interactions] | High throughput | no | no |
| CERS5_HUMAN | [view interactions] | High throughput | no | yes |
| LMBR1_HUMAN | [view interactions] | High throughput | no | yes |
| ARV1_HUMAN | [view interactions] | High throughput | no | yes |
| VAMP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CKLF6_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CREL1_HUMAN | [view interactions] | High throughput | no | yes |
| LRC8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALG3_HUMAN | [view interactions] | High throughput | no | yes |
| GP1BB_HUMAN | [view interactions] | High throughput | no | no |
| TPC1_HUMAN | [view interactions] | High throughput | no | yes |
| AGRL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2B4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T161B_HUMAN | [view interactions] | High throughput | no | no |
| MFS12_HUMAN | [view interactions] | High throughput | no | yes |
| CKLF4_HUMAN | [view interactions] | High throughput | no | yes |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| S35F2_HUMAN | [view interactions] | High throughput | no | yes |
| MITOS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G137A_HUMAN | [view interactions] | High throughput | no | no |
| TTYH3_HUMAN | [view interactions] | High throughput | no | yes |
| ADCY6_HUMAN | [view interactions] | High throughput | no | yes |
| ZDH13_HUMAN | [view interactions] | High throughput | no | no |
| VMA21_HUMAN | [view interactions] | High throughput | no | no |
| EMC6_HUMAN | [view interactions] | High throughput | no | yes |
| PIGW_HUMAN | [view interactions] | High throughput | no | no |
| SEC20_HUMAN | [view interactions] | High throughput | no | yes |
| TSN15_HUMAN | [view interactions] | High throughput | no | yes |
| CTLA4_HUMAN | [view interactions] | High throughput | no | no |
| TNF18_HUMAN | [view interactions] | High throughput | no | no |
| PCD19_HUMAN | [view interactions] | High throughput | no | yes |
| TTYH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GAMT_HUMAN | [view interactions] | High throughput | no | no |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNX14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNX13_HUMAN | [view interactions] | High throughput | no | no |
| SYPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DERL2_HUMAN | [view interactions] | High throughput | no | yes |
| TR10C_HUMAN | [view interactions] | High throughput | no | no |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| AGRE2_HUMAN | [view interactions] | High throughput | no | no |
| LRC8E_HUMAN | [view interactions] | High throughput | no | no |
| STR3N_HUMAN | [view interactions] | High throughput | no | yes |
| ERMP1_HUMAN | [view interactions] | High throughput | no | no |
| TR10B_HUMAN | [view interactions] | High throughput | no | no |
| ERGI3_HUMAN | [view interactions] | High throughput | no | yes |
| GPAT4_HUMAN | [view interactions] | High throughput | no | yes |
| TPSN_HUMAN | [view interactions] | High throughput | no | yes |
| AGRG6_HUMAN | [view interactions] | High throughput | no | no |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| SPTC2_HUMAN | [view interactions] | High throughput | no | no |
| GPI8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DHC24_HUMAN | [view interactions] | High throughput | no | yes |
| PTSS2_HUMAN | [view interactions] | High throughput | no | yes |
| MSMO1_HUMAN | [view interactions] | High throughput | no | yes |
| T126A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FA8A1_HUMAN | [view interactions] | High throughput | no | yes |
| ALG11_HUMAN | [view interactions] | High throughput | no | yes |
| GOSR2_HUMAN | [view interactions] | High throughput | no | yes |
| SGMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCD_HUMAN | [view interactions] | High throughput | no | yes |
| OXA1L_HUMAN | [view interactions] | High throughput | no | yes |
| TM9S1_HUMAN | [view interactions] | High throughput | no | yes |
| TM9S4_HUMAN | [view interactions] | High throughput | no | yes |
| TMEM9_HUMAN | [view interactions] | High throughput | no | no |
| YIPF6_HUMAN | [view interactions] | High throughput | no | yes |
| TM9S2_HUMAN | [view interactions] | High throughput | no | yes |
| KDSR_HUMAN | [view interactions] | High throughput | no | yes |
| ACAD9_HUMAN | [view interactions] | High throughput | no | yes |
| SCAM3_HUMAN | [view interactions] | High throughput | no | no |
| PIGT_HUMAN | [view interactions] | High throughput | no | no |
| K2013_HUMAN | [view interactions] | High throughput | no | yes |
| T106B_HUMAN | [view interactions] | High throughput | no | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| AR6P6_HUMAN | [view interactions] | High throughput | no | yes |
| P4HTM_HUMAN | [view interactions] | High throughput | no | yes |
| PIGS_HUMAN | [view interactions] | High throughput | no | yes |
| TM9S3_HUMAN | [view interactions] | High throughput | no | yes |
| GBG13_HUMAN | [view interactions] | Computational | no | no |
| AKP13_HUMAN | [view interactions] | Computational | no | yes |
| FAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| P85A_HUMAN | [view interactions] | Computational | no | yes |
| GNAZ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GNB5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GBB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GBG7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GNA12_HUMAN | [view interactions] | Computational | no | no |
| GBB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ACM1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GBG2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| JUN_HUMAN | [view interactions] | Computational | no | yes |
| LPAR5_HUMAN | [view interactions] | Computational | no | yes |
| TF65_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NFKB1_HUMAN | [view interactions] | Computational | no | yes |
| IL8_HUMAN | [view interactions] | Computational | no | no |
| GNA13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LPAR3_HUMAN | [view interactions] | Computational | no | no |
| EGFR_HUMAN | [view interactions] | Computational | no | no |
| GBG1_HUMAN | [view interactions] | Computational | no | no |
| GNAQ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GBG12_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GBG4_HUMAN | [view interactions] | Computational | no | no |
| GBG11_HUMAN | [view interactions] | Computational | no | no |
| LPAR6_HUMAN | [view interactions] | Computational | no | no |
| LPAR2_HUMAN | [view interactions] | Computational | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| GBG8_HUMAN | [view interactions] | Computational | no | no |
| IKBA_HUMAN | [view interactions] | Computational | no | yes |
| GBB4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GBG3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CASP3_HUMAN | [view interactions] | Computational | no | yes |
| PLD2_HUMAN | [view interactions] | Computational | no | yes |
| GBG10_HUMAN | [view interactions] | Computational | no | no |
| GNAO_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PK3CB_HUMAN | [view interactions] | Computational | no | yes |
| GNAI3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GBG5_HUMAN | [view interactions] | Computational | no | no |
| GAB1_HUMAN | [view interactions] | Computational | no | yes |
| GBGT2_HUMAN | [view interactions] | Computational | no | no |
| FOS_HUMAN | [view interactions] | Computational | no | yes |
| GBB3_HUMAN | [view interactions] | Computational | no | yes |
| ACM2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PAR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LPAR4_HUMAN | [view interactions] | Computational | no | no |
| THRB_HUMAN | [view interactions] | Computational | no | no |
| FAK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GNAI2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ANGT_HUMAN | [view interactions] | Computational | no | no |