Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PCDH1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May be involved in cell-cell interaction processes and in cell adhesion. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PCDH1_HUMAN
GO:0046872 metal ion binding 42.8571 4 yes
GO:0016462 pyrophosphatase activity 42.8571 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 42.8571 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 42.8571 6 no
GO:0005509 calcium ion binding 28.5714 5 yes
GO:0003924 GTPase activity 28.5714 7 no
GO:0005525 GTP binding 28.5714 5 no
GO:0017076 purine nucleotide binding 28.5714 4 no
GO:0019001 guanyl nucleotide binding 28.5714 5 no
GO:0019003 GDP binding 28.5714 4 no
GO:0032555 purine ribonucleotide binding 28.5714 4 no
GO:0032561 guanyl ribonucleotide binding 28.5714 5 no
GO:0035639 purine ribonucleoside triphosphate binding 28.5714 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in PCDH1_HUMAN
GO:0048522 positive regulation of cellular process 85.7143 4 no
GO:0009893 positive regulation of metabolic process 57.1429 4 no
GO:0010604 positive regulation of macromolecule metabolic process 57.1429 5 no
GO:0031323 regulation of cellular metabolic process 57.1429 4 no
GO:0031325 positive regulation of cellular metabolic process 57.1429 5 no
GO:0048523 negative regulation of cellular process 57.1429 4 no
GO:0051171 regulation of nitrogen compound metabolic process 57.1429 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 57.1429 5 no
GO:0060255 regulation of macromolecule metabolic process 57.1429 4 no
GO:0080090 regulation of primary metabolic process 57.1429 4 no
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 42.8571 4 yes
GO:0006355 regulation of DNA-templated transcription 42.8571 6 no
GO:0009889 regulation of biosynthetic process 42.8571 4 no
GO:0009891 positive regulation of biosynthetic process 42.8571 5 no
GO:0010468 regulation of gene expression 42.8571 5 no
GO:0010556 regulation of macromolecule biosynthetic process 42.8571 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 42.8571 6 no
GO:0010646 regulation of cell communication 42.8571 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 42.8571 5 no
GO:0022607 cellular component assembly 42.8571 4 no
GO:0030334 regulation of cell migration 42.8571 5 no
GO:0031326 regulation of cellular biosynthetic process 42.8571 5 no
GO:0031328 positive regulation of cellular biosynthetic process 42.8571 6 no
GO:0034329 cell junction assembly 42.8571 5 no
GO:0034330 cell junction organization 42.8571 4 no
GO:0045893 positive regulation of DNA-templated transcription 42.8571 7 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 42.8571 6 no
GO:0051246 regulation of protein metabolic process 42.8571 5 no
GO:0051252 regulation of RNA metabolic process 42.8571 5 no
GO:0051254 positive regulation of RNA metabolic process 42.8571 6 no
GO:1902680 positive regulation of RNA biosynthetic process 42.8571 7 no
GO:1903506 regulation of nucleic acid-templated transcription 42.8571 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 42.8571 8 no
GO:2000145 regulation of cell motility 42.8571 4 no
GO:2001141 regulation of RNA biosynthetic process 42.8571 6 no
GO:0044087 regulation of cellular component biogenesis 42.8571 4 no
GO:0044089 positive regulation of cellular component biogenesis 42.8571 5 no
GO:0051128 regulation of cellular component organization 42.8571 4 no
GO:0051130 positive regulation of cellular component organization 42.8571 5 no
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 28.5714 5 yes
GO:0007416 synapse assembly 28.5714 6 no
GO:0030030 cell projection organization 28.5714 4 no
GO:0030155 regulation of cell adhesion 28.5714 4 no
GO:0031175 neuron projection development 28.5714 6 no
GO:0032386 regulation of intracellular transport 28.5714 5 no
GO:0032388 positive regulation of intracellular transport 28.5714 5 no
GO:0032880 regulation of protein localization 28.5714 5 no
GO:0033157 regulation of intracellular protein transport 28.5714 6 no
GO:0050804 modulation of chemical synaptic transmission 28.5714 5 no
GO:0050808 synapse organization 28.5714 5 no
GO:0051049 regulation of transport 28.5714 4 no
GO:0051050 positive regulation of transport 28.5714 4 no
GO:0051222 positive regulation of protein transport 28.5714 5 no
GO:0051223 regulation of protein transport 28.5714 5 no
GO:0060341 regulation of cellular localization 28.5714 4 no
GO:0070201 regulation of establishment of protein localization 28.5714 6 no
GO:0090316 positive regulation of intracellular protein transport 28.5714 6 no
GO:0099177 regulation of trans-synaptic signaling 28.5714 4 no
GO:0120036 plasma membrane bounded cell projection organization 28.5714 5 no
GO:1903829 positive regulation of protein localization 28.5714 5 no
GO:1904951 positive regulation of establishment of protein localization 28.5714 6 no
GO:0000165 MAPK cascade 28.5714 4 no
GO:0007264 small GTPase mediated signal transduction 28.5714 4 no
GO:0007265 Ras protein signal transduction 28.5714 5 no
GO:0008284 positive regulation of cell population proliferation 28.5714 5 no
GO:0042127 regulation of cell population proliferation 28.5714 4 no
GO:0050678 regulation of epithelial cell proliferation 28.5714 5 no
GO:0050679 positive regulation of epithelial cell proliferation 28.5714 6 no
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0001934 positive regulation of protein phosphorylation 28.5714 8 no
GO:0006357 regulation of transcription by RNA polymerase II 28.5714 7 no
GO:0009892 negative regulation of metabolic process 28.5714 4 no
GO:0009966 regulation of signal transduction 28.5714 4 no
GO:0009967 positive regulation of signal transduction 28.5714 5 no
GO:0010562 positive regulation of phosphorus metabolic process 28.5714 6 no
GO:0010605 negative regulation of macromolecule metabolic process 28.5714 5 no
GO:0010638 positive regulation of organelle organization 28.5714 6 no
GO:0010647 positive regulation of cell communication 28.5714 5 no
GO:0010941 regulation of cell death 28.5714 4 no
GO:0019220 regulation of phosphate metabolic process 28.5714 6 no
GO:0023056 positive regulation of signaling 28.5714 4 no
GO:0030335 positive regulation of cell migration 28.5714 6 no
GO:0031344 regulation of cell projection organization 28.5714 5 no
GO:0031346 positive regulation of cell projection organization 28.5714 6 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0031401 positive regulation of protein modification process 28.5714 7 no
GO:0033043 regulation of organelle organization 28.5714 5 no
GO:0040017 positive regulation of locomotion 28.5714 4 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0042327 positive regulation of phosphorylation 28.5714 8 no
GO:0042981 regulation of apoptotic process 28.5714 6 no
GO:0043066 negative regulation of apoptotic process 28.5714 7 no
GO:0043067 regulation of programmed cell death 28.5714 5 no
GO:0043069 negative regulation of programmed cell death 28.5714 6 no
GO:0045937 positive regulation of phosphate metabolic process 28.5714 7 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 no
GO:0051174 regulation of phosphorus metabolic process 28.5714 5 no
GO:0051240 positive regulation of multicellular organismal process 28.5714 4 no
GO:0051247 positive regulation of protein metabolic process 28.5714 6 no
GO:0060491 regulation of cell projection assembly 28.5714 5 no
GO:0060548 negative regulation of cell death 28.5714 5 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 28.5714 6 no
GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 28.5714 6 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 28.5714 6 no
GO:2000147 positive regulation of cell motility 28.5714 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
YAP1_HUMAN [view interactions] High throughput no yes
SMAD3_HUMAN [view interactions] High throughput no yes
MCAF1_HUMAN [view entry] [view interactions] High throughput yes yes
ZNFX1_HUMAN [view interactions] High throughput no yes
TF3C3_HUMAN [view interactions] High throughput no no
C19L2_HUMAN [view interactions] High throughput no yes
TRIB1_HUMAN [view interactions] High throughput no no
ABCA2_HUMAN [view interactions] High throughput no yes
ITPI2_HUMAN [view interactions] High throughput no yes
DCAF4_HUMAN [view interactions] High throughput no yes
ALBU_HUMAN [view interactions] High throughput no no
VKOR1_HUMAN [view interactions] High throughput no yes
ACBP_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
SPSB4_HUMAN [view interactions] High throughput no no
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
RYK_HUMAN [view interactions] High throughput no no
CORT_HUMAN [view interactions] High throughput no no
LY86_HUMAN [view interactions] High throughput no no
CRLF1_HUMAN [view interactions] High throughput no no
SPSB2_HUMAN [view interactions] High throughput no no
ARL4D_HUMAN [view interactions] High throughput no no
SGCA_HUMAN [view interactions] High throughput no yes
FCGRN_HUMAN [view interactions] High throughput no yes
GPX7_HUMAN [view interactions] High throughput no no
I13R2_HUMAN [view interactions] High throughput no no
PCDAB_HUMAN [view interactions] High throughput no no
MO2R1_HUMAN [view interactions] High throughput no no
PVR_HUMAN [view interactions] High throughput no yes
CLC4A_HUMAN [view interactions] High throughput no no
PD1L2_HUMAN [view interactions] High throughput no yes
NXPH1_HUMAN [view interactions] High throughput no no
NXPH2_HUMAN [view interactions] High throughput no no
KI3L1_HUMAN [view interactions] High throughput no no
SDF2L_HUMAN [view interactions] High throughput no yes
BSSP4_HUMAN [view interactions] High throughput no no
IFNE_HUMAN [view interactions] High throughput no no
VSIG4_HUMAN [view interactions] High throughput no no
BY55_HUMAN [view interactions] High throughput no no
SRP14_HUMAN [view interactions] High throughput no no
IL20_HUMAN [view interactions] High throughput no no
ICAM2_HUMAN [view interactions] High throughput no no
PLPR2_HUMAN [view interactions] High throughput no yes
CD48_HUMAN [view interactions] High throughput no no
CD70_HUMAN [view interactions] High throughput no no
PCDG4_HUMAN [view interactions] High throughput no no
UPK2_HUMAN [view interactions] High throughput no no
LIRB4_HUMAN [view interactions] High throughput no no
ICOS_HUMAN [view interactions] High throughput no no
NXPH3_HUMAN [view interactions] High throughput no no
SIA8B_HUMAN [view interactions] High throughput no yes
PCDB7_HUMAN [view interactions] High throughput no yes
DKKL1_HUMAN [view interactions] High throughput no no
CADH8_HUMAN [view interactions] High throughput no no
CEA21_HUMAN [view interactions] High throughput no yes
CD4_HUMAN [view interactions] High throughput no no
FLRT1_HUMAN [view interactions] High throughput no no
CAD12_HUMAN [view interactions] High throughput no no
CBLN4_HUMAN [view interactions] High throughput no no
ITA5_HUMAN [view entry] [view interactions] High throughput yes no
RAE1E_HUMAN [view interactions] High throughput no no
MICA_HUMAN [view interactions] High throughput no no
SACA1_HUMAN [view interactions] High throughput no no
PCD20_HUMAN [view interactions] High throughput no no
IL1R2_HUMAN [view interactions] High throughput no no
TM11A_HUMAN [view interactions] High throughput no no
LRN4L_HUMAN [view interactions] High throughput no yes
FCGR1_HUMAN [view interactions] High throughput no no
PRG2_HUMAN [view interactions] High throughput no no
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no