Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ADA23_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ADA23_HUMAN
GO:0004175 endopeptidase activity 27.2727 4 yes
GO:0004222 metalloendopeptidase activity 27.2727 5 yes
GO:0008237 metallopeptidase activity 27.2727 4 yes
GO:0043169 cation binding 27.2727 4 no
GO:0046872 metal ion binding 27.2727 5 no
GO:0003723 RNA binding 27.2727 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in ADA23_HUMAN
GO:0048523 negative regulation of cellular process 63.6364 4 no
GO:0010646 regulation of cell communication 54.5455 4 no
GO:0006508 proteolysis 45.4545 4 yes
GO:0022607 cellular component assembly 45.4545 4 no
GO:0050804 modulation of chemical synaptic transmission 45.4545 5 no
GO:0051128 regulation of cellular component organization 45.4545 4 no
GO:0060255 regulation of macromolecule metabolic process 45.4545 4 no
GO:0080090 regulation of primary metabolic process 45.4545 4 no
GO:0099177 regulation of trans-synaptic signaling 45.4545 4 no
GO:0008104 protein localization 45.4545 4 no
GO:0009966 regulation of signal transduction 36.3636 4 no
GO:0048522 positive regulation of cellular process 36.3636 4 no
GO:0050807 regulation of synapse organization 36.3636 5 no
GO:0051246 regulation of protein metabolic process 36.3636 5 no
GO:0006996 organelle organization 36.3636 4 no
GO:0009889 regulation of biosynthetic process 27.2727 4 no
GO:0009890 negative regulation of biosynthetic process 27.2727 5 no
GO:0009892 negative regulation of metabolic process 27.2727 4 no
GO:0009893 positive regulation of metabolic process 27.2727 4 no
GO:0010468 regulation of gene expression 27.2727 6 no
GO:0010556 regulation of macromolecule biosynthetic process 27.2727 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 27.2727 6 no
GO:0010604 positive regulation of macromolecule metabolic process 27.2727 5 no
GO:0010605 negative regulation of macromolecule metabolic process 27.2727 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 27.2727 5 no
GO:0030030 cell projection organization 27.2727 4 no
GO:0030155 regulation of cell adhesion 27.2727 4 no
GO:0031323 regulation of cellular metabolic process 27.2727 4 no
GO:0031324 negative regulation of cellular metabolic process 27.2727 5 no
GO:0031326 regulation of cellular biosynthetic process 27.2727 5 no
GO:0031327 negative regulation of cellular biosynthetic process 27.2727 6 no
GO:0031344 regulation of cell projection organization 27.2727 5 no
GO:0042127 regulation of cell population proliferation 27.2727 4 no
GO:0051049 regulation of transport 27.2727 4 no
GO:0051129 negative regulation of cellular component organization 27.2727 5 no
GO:0051247 positive regulation of protein metabolic process 27.2727 6 no
GO:0051252 regulation of RNA metabolic process 27.2727 5 no
GO:0099175 regulation of postsynapse organization 27.2727 6 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 27.2727 6 no
GO:0120036 plasma membrane bounded cell projection organization 27.2727 5 no
GO:0009894 regulation of catabolic process 27.2727 4 no
GO:0007417 central nervous system development 18.1818 4 yes
GO:0071310 cellular response to organic substance 18.1818 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
1433Z_HUMAN [view entry] [view interactions] Low throughput yes yes
RYR1_HUMAN [view interactions] High throughput no no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
DYR1A_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
ADA11_HUMAN [view entry] [view interactions] High throughput yes yes
FBX2_HUMAN [view entry] [view interactions] High throughput yes yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
PRRT2_HUMAN [view entry] [view interactions] High throughput yes no
ADA12_HUMAN [view interactions] High throughput no no
ADA19_HUMAN [view interactions] High throughput no no
ADAM2_HUMAN [view interactions] High throughput no no
ADA22_HUMAN [view entry] [view interactions] High throughput yes no
ADA28_HUMAN [view interactions] High throughput no no
ADA32_HUMAN [view interactions] High throughput no no
ADAM5_HUMAN [view interactions] High throughput no no
ADAM7_HUMAN [view interactions] High throughput no no
ADAM8_HUMAN [view interactions] High throughput no yes