Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

EF1B_HUMAN

EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. [View more on UniProt]

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in EF1B_HUMAN
GO:0003723 RNA binding 68.5039 4 no
GO:0003746 translation elongation factor activity 5.5118 4 yes
GO:0030695 GTPase regulator activity 3.1496 4 yes
GO:0005085 guanyl-nucleotide exchange factor activity 2.3622 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in EF1B_HUMAN
GO:0009059 macromolecule biosynthetic process 64.5669 4 yes
GO:0034645 cellular macromolecule biosynthetic process 62.9921 4 yes
GO:0044271 cellular nitrogen compound biosynthetic process 62.2047 4 no
GO:0043603 cellular amide metabolic process 60.6299 4 no
GO:0006518 peptide metabolic process 59.8425 4 no
GO:0043604 amide biosynthetic process 59.8425 5 no
GO:1901566 organonitrogen compound biosynthetic process 59.8425 4 no
GO:0006412 translation 59.0551 4 no
GO:0043043 peptide biosynthetic process 59.0551 5 no
GO:0002181 cytoplasmic translation 55.9055 5 no
GO:0051171 regulation of nitrogen compound metabolic process 40.1575 4 no
GO:0060255 regulation of macromolecule metabolic process 40.1575 4 no
GO:0080090 regulation of primary metabolic process 40.1575 4 no
GO:0048522 positive regulation of cellular process 37.0079 4 no
GO:0031323 regulation of cellular metabolic process 36.2205 4 no
GO:0048523 negative regulation of cellular process 32.2835 4 no
GO:0010468 regulation of gene expression 31.4961 5 no
GO:0051246 regulation of protein metabolic process 31.4961 5 no
GO:0010646 regulation of cell communication 28.3465 4 no
GO:0009893 positive regulation of metabolic process 26.7717 4 no
GO:0009966 regulation of signal transduction 26.7717 4 no
GO:0022607 cellular component assembly 26.7717 4 no
GO:0090304 nucleic acid metabolic process 25.1969 4 no
GO:0009889 regulation of biosynthetic process 25.1969 4 no
GO:0010556 regulation of macromolecule biosynthetic process 25.1969 5 no
GO:0031326 regulation of cellular biosynthetic process 25.1969 5 no
GO:0010604 positive regulation of macromolecule metabolic process 24.4094 5 no
GO:0009892 negative regulation of metabolic process 23.6220 4 no
GO:0010941 regulation of cell death 23.6220 4 no
GO:0010605 negative regulation of macromolecule metabolic process 22.8346 5 no
GO:1902531 regulation of intracellular signal transduction 22.8346 5 no
GO:0016070 RNA metabolic process 22.0472 5 no
GO:0051172 negative regulation of nitrogen compound metabolic process 22.0472 5 no
GO:0042981 regulation of apoptotic process 22.0472 6 no
GO:0043067 regulation of programmed cell death 22.0472 5 no
GO:0031324 negative regulation of cellular metabolic process 21.2598 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 21.2598 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 20.4724 5 no
GO:0043933 protein-containing complex organization 20.4724 4 no
GO:0006414 translational elongation 7.0866 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in EF1B_HUMAN
DOID:0050686 organ system cancer 1.5748 3 no
DOID:574 peripheral nervous system disease 1.5748 3 no
DOID:870 neuropathy 1.5748 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TCTP_HUMAN [view entry] [view interactions] Low throughput yes yes
EF1B_HUMAN [view entry] [view interactions] Low throughput yes yes
SYVC_HUMAN [view interactions] Low throughput no yes
EF1G_HUMAN [view entry] [view interactions] Low throughput yes yes
K1C17_HUMAN [view interactions] Low throughput no no
HARS1_HUMAN [view interactions] Low throughput no yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
ERP27_HUMAN [view interactions] High throughput no no
BATF3_HUMAN [view interactions] High throughput no no
COR1A_HUMAN [view entry] [view interactions] High throughput yes no
THB_HUMAN [view interactions] High throughput no no
FBXW7_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
BOREA_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
WBP2_HUMAN [view interactions] High throughput no yes
OTUD4_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
RS2_HUMAN [view entry] [view interactions] High throughput yes yes
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
STRP1_HUMAN [view interactions] High throughput no yes
TPR_HUMAN [view interactions] High throughput no yes
NU153_HUMAN [view interactions] High throughput no yes
PLOD3_HUMAN [view interactions] High throughput no yes
SNRPA_HUMAN [view interactions] High throughput no yes
STRN4_HUMAN [view entry] [view interactions] High throughput yes yes
T2FA_HUMAN [view interactions] High throughput no yes
SRSF9_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
QCR6_HUMAN [view interactions] High throughput no yes
DNJA1_HUMAN [view entry] [view interactions] High throughput yes yes
AHNK_HUMAN [view entry] [view interactions] High throughput yes yes
ATLA3_HUMAN [view interactions] High throughput no no
AKAP8_HUMAN [view interactions] High throughput no yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
KMT2D_HUMAN [view interactions] High throughput no yes
ARMX3_HUMAN [view interactions] High throughput no no
ARF3_HUMAN [view entry] [view interactions] High throughput yes no
PYRD_HUMAN [view interactions] High throughput no yes
RL35A_HUMAN [view entry] [view interactions] High throughput yes no
RL10_HUMAN [view entry] [view interactions] High throughput yes yes
RL22L_HUMAN [view interactions] High throughput no no
RL27A_HUMAN [view entry] [view interactions] High throughput yes yes
RLA1_HUMAN [view entry] [view interactions] High throughput yes no
THNS2_HUMAN [view interactions] High throughput no no
SYAC_HUMAN [view interactions] High throughput no yes
IF5A1_HUMAN [view interactions] High throughput no yes
RACK1_HUMAN [view interactions] High throughput no yes
RL11_HUMAN [view entry] [view interactions] High throughput yes yes
RL12_HUMAN [view entry] [view interactions] High throughput yes yes
RL13_HUMAN [view entry] [view interactions] High throughput yes yes
RL14_HUMAN [view entry] [view interactions] High throughput yes yes
RL18_HUMAN [view entry] [view interactions] High throughput yes yes
RL18A_HUMAN [view entry] [view interactions] High throughput yes yes
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
RL22_HUMAN [view entry] [view interactions] High throughput yes no
RL24_HUMAN [view entry] [view interactions] High throughput yes yes
RL26_HUMAN [view entry] [view interactions] High throughput yes yes
RL3_HUMAN [view entry] [view interactions] High throughput yes yes
RL30_HUMAN [view entry] [view interactions] High throughput yes yes
RL35_HUMAN [view entry] [view interactions] High throughput yes yes
RL4_HUMAN [view entry] [view interactions] High throughput yes yes
RL6_HUMAN [view entry] [view interactions] High throughput yes yes
RL7_HUMAN [view entry] [view interactions] High throughput yes yes
RL8_HUMAN [view entry] [view interactions] High throughput yes yes
RLA0_HUMAN [view entry] [view interactions] High throughput yes yes
RLA2_HUMAN [view entry] [view interactions] High throughput yes yes
RS11_HUMAN [view entry] [view interactions] High throughput yes yes
RS13_HUMAN [view entry] [view interactions] High throughput yes yes
RS14_HUMAN [view entry] [view interactions] High throughput yes yes
RS17_HUMAN [view entry] [view interactions] High throughput yes yes
RS18_HUMAN [view entry] [view interactions] High throughput yes yes
RS19_HUMAN [view entry] [view interactions] High throughput yes no
RS20_HUMAN [view entry] [view interactions] High throughput yes yes
RS23_HUMAN [view entry] [view interactions] High throughput yes yes
RS24_HUMAN [view entry] [view interactions] High throughput yes yes
RS28_HUMAN [view entry] [view interactions] High throughput yes yes
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
RS4X_HUMAN [view entry] [view interactions] High throughput yes yes
RSSA_HUMAN [view entry] [view interactions] High throughput yes yes
IF5A2_HUMAN [view interactions] High throughput no yes
RL13A_HUMAN [view entry] [view interactions] High throughput yes yes
RL15_HUMAN [view entry] [view interactions] High throughput yes no
RL31_HUMAN [view entry] [view interactions] High throughput yes yes
RL32_HUMAN [view entry] [view interactions] High throughput yes yes
RL38_HUMAN [view entry] [view interactions] High throughput yes yes
RS15A_HUMAN [view entry] [view interactions] High throughput yes yes
RS21_HUMAN [view entry] [view interactions] High throughput yes yes
RS26_HUMAN [view entry] [view interactions] High throughput yes yes
RS27A_HUMAN [view entry] [view interactions] High throughput yes yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
RS5_HUMAN [view entry] [view interactions] High throughput yes yes
RS7_HUMAN [view entry] [view interactions] High throughput yes yes
RS8_HUMAN [view entry] [view interactions] High throughput yes no
RS9_HUMAN [view entry] [view interactions] High throughput yes yes
EWS_HUMAN [view interactions] High throughput no yes
AGR2_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
NAA40_HUMAN [view interactions] High throughput no no
OPTN_HUMAN [view interactions] High throughput no yes
AP2C_HUMAN [view interactions] High throughput no no
MK13_HUMAN [view interactions] High throughput no yes
H2AX_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL1_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view interactions] High throughput no no
AIM2_HUMAN [view interactions] High throughput no no
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
RRBP1_HUMAN [view entry] [view interactions] High throughput yes yes
AF17_HUMAN [view interactions] High throughput no yes
EF1A2_HUMAN [view entry] [view interactions] High throughput yes yes
SHLD3_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
CRY1_HUMAN [view interactions] High throughput no yes
PTK6_HUMAN [view interactions] High throughput no yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
MTA2_HUMAN [view interactions] High throughput no yes
CNR2_HUMAN [view interactions] High throughput no yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
SDHA_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
2ABB_HUMAN [view interactions] High throughput no yes
RD23B_HUMAN [view interactions] High throughput no yes
ATF3_HUMAN [view interactions] High throughput no yes
CDN1A_HUMAN [view interactions] High throughput no no
CEBPD_HUMAN [view interactions] High throughput no no
NCF1_HUMAN [view interactions] High throughput no no
TRI63_HUMAN [view interactions] High throughput no no
TRI55_HUMAN [view interactions] High throughput no no
CRCM_HUMAN [view interactions] High throughput no no
EIF1B_HUMAN [view interactions] High throughput no no
ATG5_HUMAN [view interactions] High throughput no no
IKKE_HUMAN [view interactions] High throughput no yes
HLAB_HUMAN [view interactions] High throughput no yes
SOMA_HUMAN [view interactions] High throughput no no
EPB41_HUMAN [view entry] [view interactions] High throughput yes no
IF4A2_HUMAN [view entry] [view interactions] High throughput yes yes
ARP6_HUMAN [view interactions] High throughput no yes
MK03_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
AAPK1_HUMAN [view interactions] High throughput no no
BMI1_HUMAN [view interactions] High throughput no yes
CNDD3_HUMAN [view interactions] High throughput no no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
DHRS2_HUMAN [view interactions] High throughput no no
CSK21_HUMAN [view entry] [view interactions] High throughput yes yes
SPRY4_HUMAN [view interactions] High throughput no yes
TIMP1_HUMAN [view interactions] High throughput no no
ULK2_HUMAN [view interactions] High throughput no yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
CUL1_HUMAN [view interactions] High throughput no yes
CUL2_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
KDM4C_HUMAN [view interactions] High throughput no no
HES4_HUMAN [view interactions] High throughput no no
NECD_HUMAN [view interactions] High throughput no no
MGMT_HUMAN [view interactions] High throughput no no
SRRM2_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
CD4_HUMAN [view interactions] High throughput no no
TFE2_HUMAN [view interactions] High throughput no no
FBX6_HUMAN [view interactions] High throughput no yes
SMUF1_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
FBX32_HUMAN [view interactions] High throughput no no
IGSF8_HUMAN [view entry] [view interactions] High throughput yes no
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
HUWE1_HUMAN [view interactions] High throughput no yes
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
CUL7_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
KTN1_HUMAN [view entry] [view interactions] High throughput yes yes
MCM2_HUMAN [view interactions] High throughput no no
RPTOR_HUMAN [view interactions] High throughput no yes
EF1D_HUMAN [view entry] [view interactions] High throughput yes yes
FACD2_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
BRCA1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
TGFB1_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
TNIP2_HUMAN [view interactions] High throughput no yes
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
ESR2_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
CEBPA_HUMAN [view interactions] High throughput no yes
GPC1_HUMAN [view entry] [view interactions] High throughput yes no
MYC_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
PSA3_HUMAN [view interactions] High throughput no no
HDAC6_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
FAF1_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
TFE3_HUMAN [view interactions] High throughput no yes
ATX3_HUMAN [view interactions] High throughput no yes
MGDP1_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
ARI2_HUMAN [view interactions] High throughput no no
YAP1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
HIF1N_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
CHM4C_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
PD1L1_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
FZR1_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
PAGE4_HUMAN [view interactions] High throughput no no
RL39_HUMAN [view interactions] Computational no no
RL36L_HUMAN [view interactions] Computational no no
RL37A_HUMAN [view entry] [view interactions] Computational yes yes
EIF3E_HUMAN [view entry] [view interactions] Computational yes yes
RS12_HUMAN [view entry] [view interactions] Computational yes yes
RS25_HUMAN [view entry] [view interactions] Computational yes yes
RL27_HUMAN [view entry] [view interactions] Computational yes yes
SYVM_HUMAN [view interactions] Computational no yes
RS16_HUMAN [view entry] [view interactions] Computational yes yes
RL36_HUMAN [view entry] [view interactions] Computational yes yes
RL28_HUMAN [view entry] [view interactions] Computational yes yes
RL9_HUMAN [view entry] [view interactions] Computational yes yes
RS6_HUMAN [view entry] [view interactions] Computational yes yes
MTPN_HUMAN [view interactions] Computational no yes
RL23A_HUMAN [view entry] [view interactions] Computational yes yes
PSA5_HUMAN [view interactions] Computational no yes
UBB_HUMAN [view entry] [view interactions] Computational yes yes
RL40_HUMAN [view entry] [view interactions] Computational yes yes
RS15_HUMAN [view entry] [view interactions] Computational yes yes
RL21_HUMAN [view entry] [view interactions] Computational yes yes
RL37_HUMAN [view entry] [view interactions] Computational yes no
RL34_HUMAN [view entry] [view interactions] Computational yes yes
ENOPH_HUMAN [view interactions] Computational no yes
RL10A_HUMAN [view entry] [view interactions] Computational yes yes
RS29_HUMAN [view interactions] Computational no yes
RL23_HUMAN [view entry] [view interactions] Computational yes yes
RL10L_HUMAN [view interactions] Computational no no
RL5_HUMAN [view entry] [view interactions] Computational yes yes
RS10_HUMAN [view entry] [view interactions] Computational yes yes
EF2_HUMAN [view entry] [view interactions] Computational yes yes
RL26L_HUMAN [view interactions] Computational no yes
ERF1_HUMAN [view interactions] Computational no yes
RL29_HUMAN [view entry] [view interactions] Computational yes yes