Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

EF1B_HUMAN

EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. [View more on UniProt]

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Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in EF1B_HUMAN
GO:0003723 RNA binding 59.4828 4 no
GO:0003746 translation elongation factor activity 5.1724 4 yes
GO:0030695 GTPase regulator activity 4.3103 4 yes
GO:0005085 guanyl-nucleotide exchange factor activity 2.5862 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in EF1B_HUMAN
GO:0009059 macromolecule biosynthetic process 57.7586 4 yes
GO:1901566 organonitrogen compound biosynthetic process 48.2759 4 no
GO:0006412 translation 47.4138 4 no
GO:0002181 cytoplasmic translation 44.8276 5 no
GO:0060255 regulation of macromolecule metabolic process 44.8276 4 no
GO:0080090 regulation of primary metabolic process 44.8276 4 no
GO:0031323 regulation of cellular metabolic process 40.5172 4 no
GO:0048522 positive regulation of cellular process 38.7931 4 no
GO:0048523 negative regulation of cellular process 38.7931 4 no
GO:0009889 regulation of biosynthetic process 35.3448 4 no
GO:0010468 regulation of gene expression 34.4828 6 no
GO:0010556 regulation of macromolecule biosynthetic process 34.4828 5 no
GO:0031326 regulation of cellular biosynthetic process 34.4828 5 no
GO:0022607 cellular component assembly 31.8966 4 no
GO:0051246 regulation of protein metabolic process 31.8966 5 no
GO:0010646 regulation of cell communication 31.0345 4 no
GO:0009893 positive regulation of metabolic process 30.1724 4 no
GO:0009966 regulation of signal transduction 29.3103 4 no
GO:0010604 positive regulation of macromolecule metabolic process 27.5862 5 no
GO:0042981 regulation of apoptotic process 26.7241 5 no
GO:0043067 regulation of programmed cell death 26.7241 4 no
GO:0051128 regulation of cellular component organization 26.7241 4 no
GO:0009892 negative regulation of metabolic process 25.8621 4 no
GO:1902531 regulation of intracellular signal transduction 25.8621 5 no
GO:0090304 nucleic acid metabolic process 25.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 25.0000 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.0000 5 no
GO:0043933 protein-containing complex organization 24.1379 4 no
GO:0006996 organelle organization 23.2759 4 no
GO:0031325 positive regulation of cellular metabolic process 23.2759 5 no
GO:0051252 regulation of RNA metabolic process 23.2759 5 no
GO:0048584 positive regulation of response to stimulus 21.5517 4 no
GO:0048585 negative regulation of response to stimulus 21.5517 4 no
GO:0031324 negative regulation of cellular metabolic process 21.5517 5 no
GO:0006355 regulation of DNA-templated transcription 20.6897 7 no
GO:0008104 protein localization 20.6897 4 no
GO:0031399 regulation of protein modification process 20.6897 6 no
GO:2001141 regulation of RNA biosynthetic process 20.6897 6 no
GO:0006414 translational elongation 6.8966 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SYVC_HUMAN [view interactions] Low throughput no yes
EF1G_HUMAN [view entry] [view interactions] Low throughput yes yes
K1C17_HUMAN [view interactions] Low throughput no no
HARS1_HUMAN [view interactions] Low throughput no yes
TCTP_HUMAN [view entry] [view interactions] Low throughput yes yes
EF1B_HUMAN [view entry] [view interactions] Low throughput yes yes
RS2_HUMAN [view entry] [view interactions] High throughput yes yes
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
STRP1_HUMAN [view interactions] High throughput no yes
TPR_HUMAN [view interactions] High throughput no yes
NU153_HUMAN [view interactions] High throughput no yes
PLOD3_HUMAN [view interactions] High throughput no yes
SNRPA_HUMAN [view interactions] High throughput no yes
STRN4_HUMAN [view entry] [view interactions] High throughput yes yes
T2FA_HUMAN [view interactions] High throughput no yes
SRSF9_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
QCR6_HUMAN [view interactions] High throughput no yes
DNJA1_HUMAN [view entry] [view interactions] High throughput yes yes
AHNK_HUMAN [view entry] [view interactions] High throughput yes yes
ATLA3_HUMAN [view interactions] High throughput no no
AKAP8_HUMAN [view interactions] High throughput no yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
KMT2D_HUMAN [view interactions] High throughput no yes
ARMX3_HUMAN [view interactions] High throughput no no
ARF3_HUMAN [view entry] [view interactions] High throughput yes no
PYRD_HUMAN [view interactions] High throughput no yes
RL35A_HUMAN [view entry] [view interactions] High throughput yes no
RL10_HUMAN [view entry] [view interactions] High throughput yes yes
RL22L_HUMAN [view interactions] High throughput no no
RL27A_HUMAN [view entry] [view interactions] High throughput yes yes
RLA1_HUMAN [view entry] [view interactions] High throughput yes no
THNS2_HUMAN [view interactions] High throughput no no
SYAC_HUMAN [view interactions] High throughput no yes
IF5A1_HUMAN [view interactions] High throughput no yes
RACK1_HUMAN [view interactions] High throughput no yes
RL11_HUMAN [view entry] [view interactions] High throughput yes yes
RL12_HUMAN [view entry] [view interactions] High throughput yes yes
RL13_HUMAN [view entry] [view interactions] High throughput yes yes
RL14_HUMAN [view entry] [view interactions] High throughput yes yes
RL18_HUMAN [view entry] [view interactions] High throughput yes yes
RL18A_HUMAN [view entry] [view interactions] High throughput yes yes
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
RL22_HUMAN [view entry] [view interactions] High throughput yes no
RL24_HUMAN [view entry] [view interactions] High throughput yes yes
RL26_HUMAN [view entry] [view interactions] High throughput yes yes
RL3_HUMAN [view entry] [view interactions] High throughput yes yes
RL30_HUMAN [view entry] [view interactions] High throughput yes yes
RL35_HUMAN [view entry] [view interactions] High throughput yes yes
RL4_HUMAN [view entry] [view interactions] High throughput yes yes
RL6_HUMAN [view entry] [view interactions] High throughput yes yes
RL7_HUMAN [view entry] [view interactions] High throughput yes yes
RL8_HUMAN [view entry] [view interactions] High throughput yes yes
RLA0_HUMAN [view entry] [view interactions] High throughput yes yes
RLA2_HUMAN [view entry] [view interactions] High throughput yes yes
RS11_HUMAN [view entry] [view interactions] High throughput yes yes
RS13_HUMAN [view entry] [view interactions] High throughput yes yes
RS14_HUMAN [view entry] [view interactions] High throughput yes yes
RS17_HUMAN [view entry] [view interactions] High throughput yes yes
RS18_HUMAN [view entry] [view interactions] High throughput yes yes
RS19_HUMAN [view entry] [view interactions] High throughput yes no
RS20_HUMAN [view entry] [view interactions] High throughput yes yes
RS23_HUMAN [view entry] [view interactions] High throughput yes yes
RS24_HUMAN [view entry] [view interactions] High throughput yes yes
RS28_HUMAN [view entry] [view interactions] High throughput yes yes
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
RS4X_HUMAN [view entry] [view interactions] High throughput yes yes
RSSA_HUMAN [view entry] [view interactions] High throughput yes yes
IF5A2_HUMAN [view interactions] High throughput no yes
RL13A_HUMAN [view entry] [view interactions] High throughput yes yes
AP2C_HUMAN [view interactions] High throughput no no
RL15_HUMAN [view entry] [view interactions] High throughput yes no
MK13_HUMAN [view interactions] High throughput no yes
RL31_HUMAN [view entry] [view interactions] High throughput yes yes
H2AX_HUMAN [view interactions] High throughput no yes
RL32_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
RL38_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
RS15A_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL1_HUMAN [view interactions] High throughput no yes
RS21_HUMAN [view entry] [view interactions] High throughput yes yes
GBRAP_HUMAN [view entry] [view interactions] High throughput yes no
RS26_HUMAN [view entry] [view interactions] High throughput yes yes
AIM2_HUMAN [view interactions] High throughput no no
RS27A_HUMAN [view entry] [view interactions] High throughput yes yes
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
RRBP1_HUMAN [view entry] [view interactions] High throughput yes yes
RS5_HUMAN [view entry] [view interactions] High throughput yes yes
AF17_HUMAN [view interactions] High throughput no yes
RS7_HUMAN [view entry] [view interactions] High throughput yes yes
RS8_HUMAN [view entry] [view interactions] High throughput yes no
EF1A2_HUMAN [view entry] [view interactions] High throughput yes yes
RS9_HUMAN [view entry] [view interactions] High throughput yes yes
SHLD3_HUMAN [view interactions] High throughput no yes
ATRX_HUMAN [view entry] [view interactions] High throughput yes yes
NEK4_HUMAN [view interactions] High throughput no yes
IF5_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
TNPO1_HUMAN [view entry] [view interactions] High throughput yes yes
LRRK2_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
AGR2_HUMAN [view interactions] High throughput no no
CRY1_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
PTK6_HUMAN [view interactions] High throughput no yes
NAA40_HUMAN [view interactions] High throughput no no
LCK_HUMAN [view entry] [view interactions] High throughput yes no
OPTN_HUMAN [view interactions] High throughput no yes
MTA2_HUMAN [view interactions] High throughput no yes
STING_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
CNR2_HUMAN [view entry] [view interactions] High throughput yes yes
TAOK2_HUMAN [view entry] [view interactions] High throughput yes yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
FOXO1_HUMAN [view interactions] High throughput no yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
RED1_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes
FINC_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
RFA2_HUMAN [view interactions] High throughput no yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
RFA3_HUMAN [view interactions] High throughput no yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
RFA4_HUMAN [view interactions] High throughput no yes
SDHA_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
2ABB_HUMAN [view interactions] High throughput no yes
RD23B_HUMAN [view interactions] High throughput no yes
ATF3_HUMAN [view interactions] High throughput no yes
CDN1A_HUMAN [view interactions] High throughput no no
CEBPD_HUMAN [view interactions] High throughput no no
NCF1_HUMAN [view interactions] High throughput no no
TRI63_HUMAN [view interactions] High throughput no no
TRI55_HUMAN [view interactions] High throughput no no
SIM26_HUMAN [view interactions] High throughput no no
CRCM_HUMAN [view interactions] High throughput no no
EIF1B_HUMAN [view interactions] High throughput no no
ATG5_HUMAN [view entry] [view interactions] High throughput yes no
IKKE_HUMAN [view interactions] High throughput no yes
HLAB_HUMAN [view interactions] High throughput no yes
SOMA_HUMAN [view interactions] High throughput no no
EPB41_HUMAN [view entry] [view interactions] High throughput yes no
IF4A2_HUMAN [view entry] [view interactions] High throughput yes yes
ARP6_HUMAN [view interactions] High throughput no yes
MK03_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
AAPK1_HUMAN [view interactions] High throughput no no
BMI1_HUMAN [view interactions] High throughput no yes
CNDD3_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
DHRS2_HUMAN [view interactions] High throughput no no
CSK21_HUMAN [view entry] [view interactions] High throughput yes yes
SPRY4_HUMAN [view interactions] High throughput no yes
TIMP1_HUMAN [view interactions] High throughput no no
ULK2_HUMAN [view interactions] High throughput no yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
CUL1_HUMAN [view interactions] High throughput no yes
CUL2_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
KDM4C_HUMAN [view interactions] High throughput no no
HES4_HUMAN [view interactions] High throughput no no
NECD_HUMAN [view interactions] High throughput no no
MGMT_HUMAN [view interactions] High throughput no no
SRRM2_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
CD4_HUMAN [view interactions] High throughput no no
TFE2_HUMAN [view interactions] High throughput no no
FBX6_HUMAN [view interactions] High throughput no yes
SMUF1_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
FBX32_HUMAN [view interactions] High throughput no no
IGSF8_HUMAN [view entry] [view interactions] High throughput yes no
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
HUWE1_HUMAN [view interactions] High throughput no yes
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
CUL7_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
KTN1_HUMAN [view entry] [view interactions] High throughput yes yes
MCM2_HUMAN [view interactions] High throughput no no
RPTOR_HUMAN [view interactions] High throughput no yes
EF1D_HUMAN [view entry] [view interactions] High throughput yes yes
FACD2_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
BRCA1_HUMAN [view interactions] High throughput no yes
TGFB1_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
TNIP2_HUMAN [view interactions] High throughput no yes
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
ESR2_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
CEBPA_HUMAN [view interactions] High throughput no yes
GPC1_HUMAN [view entry] [view interactions] High throughput yes no
MYC_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
PSA3_HUMAN [view interactions] High throughput no no
HDAC6_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
FAF1_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
TFE3_HUMAN [view interactions] High throughput no yes
ATX3_HUMAN [view interactions] High throughput no yes
MGDP1_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
ARI2_HUMAN [view interactions] High throughput no no
YAP1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
HIF1N_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
CHM4C_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
PD1L1_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
FZR1_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
PAGE4_HUMAN [view interactions] High throughput no no
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
ERP27_HUMAN [view interactions] High throughput no no
BATF3_HUMAN [view interactions] High throughput no no
COR1A_HUMAN [view entry] [view interactions] High throughput yes no
THB_HUMAN [view interactions] High throughput no no
FBXW7_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
SOX2_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
BOREA_HUMAN [view interactions] High throughput no yes
WWP1_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
SH3L1_HUMAN [view interactions] High throughput no yes
RNF8_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
DOT1L_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
DX39B_HUMAN [view interactions] High throughput no no
ACE2_HUMAN [view interactions] High throughput no no
CDK7_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
ASXL1_HUMAN [view interactions] High throughput no no
ASXL2_HUMAN [view interactions] High throughput no no
TET5C_HUMAN [view interactions] High throughput no yes
CBL_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
GOLI_HUMAN [view interactions] High throughput no yes
RN149_HUMAN [view interactions] High throughput no no
SMC5_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
CEMIP_HUMAN [view interactions] High throughput no no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
WBP2_HUMAN [view interactions] High throughput no yes
OTUD4_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
UBP7_HUMAN [view interactions] High throughput no yes