FBX41_HUMAN
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in FBX41_HUMAN |
---|---|---|---|---|
GO:0003779 | actin binding | 33.3333 | 4 | no |
GO:0046872 | metal ion binding | 33.3333 | 4 | no |
GO:0019900 | kinase binding | 22.2222 | 4 | no |
GO:0008270 | zinc ion binding | 22.2222 | 6 | no |
GO:0046914 | transition metal ion binding | 22.2222 | 5 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in FBX41_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 66.6667 | 4 | no |
GO:0010646 | regulation of cell communication | 66.6667 | 4 | no |
GO:0099177 | regulation of trans-synaptic signaling | 55.5556 | 4 | no |
GO:0009966 | regulation of signal transduction | 55.5556 | 4 | no |
GO:0048523 | negative regulation of cellular process | 55.5556 | 4 | no |
GO:0051128 | regulation of cellular component organization | 55.5556 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 55.5556 | 4 | no |
GO:0050804 | modulation of chemical synaptic transmission | 55.5556 | 5 | no |
GO:0030030 | cell projection organization | 44.4444 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 44.4444 | 4 | no |
GO:0010975 | regulation of neuron projection development | 44.4444 | 7 | no |
GO:0031323 | regulation of cellular metabolic process | 44.4444 | 4 | no |
GO:0031344 | regulation of cell projection organization | 44.4444 | 5 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 44.4444 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 44.4444 | 5 | no |
GO:0080090 | regulation of primary metabolic process | 44.4444 | 4 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 44.4444 | 6 | no |
GO:0042127 | regulation of cell population proliferation | 44.4444 | 4 | no |
GO:0050890 | cognition | 44.4444 | 4 | no |
GO:0008104 | protein localization | 33.3333 | 4 | no |
GO:0022607 | cellular component assembly | 33.3333 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 33.3333 | 5 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 33.3333 | 5 | no |
GO:0007612 | learning | 33.3333 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 33.3333 | 7 | no |
GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 33.3333 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 33.3333 | 5 | no |
GO:0019220 | regulation of phosphate metabolic process | 33.3333 | 6 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 33.3333 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 33.3333 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | no |
GO:0031399 | regulation of protein modification process | 33.3333 | 6 | no |
GO:0042325 | regulation of phosphorylation | 33.3333 | 7 | no |
GO:0043086 | negative regulation of catalytic activity | 33.3333 | 4 | no |
GO:0050807 | regulation of synapse organization | 33.3333 | 5 | no |
GO:0051049 | regulation of transport | 33.3333 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 33.3333 | 5 | no |
GO:0051174 | regulation of phosphorus metabolic process | 33.3333 | 5 | no |
GO:0051248 | negative regulation of protein metabolic process | 33.3333 | 6 | no |
GO:0010243 | response to organonitrogen compound | 33.3333 | 4 | no |
GO:0045595 | regulation of cell differentiation | 33.3333 | 4 | no |
GO:0051726 | regulation of cell cycle | 33.3333 | 4 | no |
GO:0071407 | cellular response to organic cyclic compound | 22.2222 | 5 | no |
GO:0071417 | cellular response to organonitrogen compound | 22.2222 | 4 | no |
GO:0071702 | organic substance transport | 22.2222 | 4 | no |
GO:0071705 | nitrogen compound transport | 22.2222 | 4 | no |
GO:1901699 | cellular response to nitrogen compound | 22.2222 | 4 | no |
GO:1901701 | cellular response to oxygen-containing compound | 22.2222 | 4 | no |
GO:2000177 | regulation of neural precursor cell proliferation | 22.2222 | 5 | no |
GO:0001558 | regulation of cell growth | 22.2222 | 4 | no |
GO:0001952 | regulation of cell-matrix adhesion | 22.2222 | 6 | no |
GO:0001954 | positive regulation of cell-matrix adhesion | 22.2222 | 7 | no |
GO:0006996 | organelle organization | 22.2222 | 4 | no |
GO:0009894 | regulation of catabolic process | 22.2222 | 4 | no |
GO:0009896 | positive regulation of catabolic process | 22.2222 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 22.2222 | 5 | no |
GO:0010647 | positive regulation of cell communication | 22.2222 | 5 | no |
GO:0010720 | positive regulation of cell development | 22.2222 | 6 | no |
GO:0010810 | regulation of cell-substrate adhesion | 22.2222 | 5 | no |
GO:0010811 | positive regulation of cell-substrate adhesion | 22.2222 | 6 | no |
GO:0023056 | positive regulation of signaling | 22.2222 | 4 | no |
GO:0030031 | cell projection assembly | 22.2222 | 5 | no |
GO:0030155 | regulation of cell adhesion | 22.2222 | 4 | no |
GO:0031329 | regulation of cellular catabolic process | 22.2222 | 5 | no |
GO:0031331 | positive regulation of cellular catabolic process | 22.2222 | 6 | no |
GO:0033365 | protein localization to organelle | 22.2222 | 5 | no |
GO:0044380 | protein localization to cytoskeleton | 22.2222 | 6 | no |
GO:0045597 | positive regulation of cell differentiation | 22.2222 | 5 | no |
GO:0045785 | positive regulation of cell adhesion | 22.2222 | 5 | no |
GO:0048584 | positive regulation of response to stimulus | 22.2222 | 4 | no |
GO:0050767 | regulation of neurogenesis | 22.2222 | 6 | no |
GO:0050769 | positive regulation of neurogenesis | 22.2222 | 6 | no |
GO:0051094 | positive regulation of developmental process | 22.2222 | 4 | no |
GO:0051240 | positive regulation of multicellular organismal process | 22.2222 | 4 | no |
GO:0051960 | regulation of nervous system development | 22.2222 | 5 | no |
GO:0051962 | positive regulation of nervous system development | 22.2222 | 5 | no |
GO:0051966 | regulation of synaptic transmission, glutamatergic | 22.2222 | 6 | no |
GO:0060284 | regulation of cell development | 22.2222 | 5 | no |
GO:0060998 | regulation of dendritic spine development | 22.2222 | 4 | no |
GO:0070925 | organelle assembly | 22.2222 | 5 | no |
GO:0120031 | plasma membrane bounded cell projection assembly | 22.2222 | 6 | no |
GO:2000026 | regulation of multicellular organismal development | 22.2222 | 4 | no |
GO:0031644 | regulation of nervous system process | 22.2222 | 5 | no |
GO:0044057 | regulation of system process | 22.2222 | 4 | no |
GO:0099601 | regulation of neurotransmitter receptor activity | 22.2222 | 4 | no |
GO:0008361 | regulation of cell size | 22.2222 | 5 | no |
GO:0010921 | regulation of phosphatase activity | 22.2222 | 5 | no |
GO:0032231 | regulation of actin filament bundle assembly | 22.2222 | 5 | no |
GO:0032535 | regulation of cellular component size | 22.2222 | 4 | no |
GO:0032956 | regulation of actin cytoskeleton organization | 22.2222 | 5 | no |
GO:0032970 | regulation of actin filament-based process | 22.2222 | 4 | no |
GO:0033043 | regulation of organelle organization | 22.2222 | 5 | no |
GO:0034330 | cell junction organization | 22.2222 | 4 | no |
GO:0035303 | regulation of dephosphorylation | 22.2222 | 7 | no |
GO:0035304 | regulation of protein dephosphorylation | 22.2222 | 7 | no |
GO:0043666 | regulation of phosphoprotein phosphatase activity | 22.2222 | 6 | no |
GO:0044087 | regulation of cellular component biogenesis | 22.2222 | 4 | no |
GO:0050808 | synapse organization | 22.2222 | 5 | no |
GO:0051129 | negative regulation of cellular component organization | 22.2222 | 5 | no |
GO:0051336 | regulation of hydrolase activity | 22.2222 | 4 | no |
GO:0051346 | negative regulation of hydrolase activity | 22.2222 | 5 | no |
GO:0051493 | regulation of cytoskeleton organization | 22.2222 | 6 | no |
GO:0110053 | regulation of actin filament organization | 22.2222 | 6 | no |
GO:1901652 | response to peptide | 22.2222 | 4 | no |
GO:1902903 | regulation of supramolecular fiber organization | 22.2222 | 5 | no |
GO:0031175 | neuron projection development | 22.2222 | 6 | no |
GO:0010563 | negative regulation of phosphorus metabolic process | 22.2222 | 6 | no |
GO:0031400 | negative regulation of protein modification process | 22.2222 | 7 | no |
GO:0032880 | regulation of protein localization | 22.2222 | 5 | no |
GO:0043085 | positive regulation of catalytic activity | 22.2222 | 4 | no |
GO:0043549 | regulation of kinase activity | 22.2222 | 5 | no |
GO:0045859 | regulation of protein kinase activity | 22.2222 | 6 | no |
GO:0045936 | negative regulation of phosphate metabolic process | 22.2222 | 7 | no |
GO:0051046 | regulation of secretion | 22.2222 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 22.2222 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 22.2222 | 6 | no |
GO:0051338 | regulation of transferase activity | 22.2222 | 4 | no |
GO:0060341 | regulation of cellular localization | 22.2222 | 4 | no |
GO:0061001 | regulation of dendritic spine morphogenesis | 22.2222 | 5 | no |
GO:0099175 | regulation of postsynapse organization | 22.2222 | 6 | no |
GO:1903530 | regulation of secretion by cell | 22.2222 | 4 | no |
GO:0006811 | ion transport | 22.2222 | 4 | no |
GO:0006812 | cation transport | 22.2222 | 5 | no |
GO:0007613 | memory | 22.2222 | 4 | no |
GO:0008285 | negative regulation of cell population proliferation | 22.2222 | 5 | no |
GO:0010468 | regulation of gene expression | 22.2222 | 5 | no |
GO:0010648 | negative regulation of cell communication | 22.2222 | 5 | no |
GO:0014070 | response to organic cyclic compound | 22.2222 | 4 | no |
GO:0023057 | negative regulation of signaling | 22.2222 | 4 | no |
GO:0030001 | metal ion transport | 22.2222 | 6 | no |
GO:0031667 | response to nutrient levels | 22.2222 | 4 | no |
GO:0032355 | response to estradiol | 22.2222 | 4 | no |
GO:0033993 | response to lipid | 22.2222 | 4 | no |
GO:0036293 | response to decreased oxygen levels | 22.2222 | 4 | no |
GO:0043269 | regulation of ion transport | 22.2222 | 5 | no |
GO:0043270 | positive regulation of ion transport | 22.2222 | 5 | no |
GO:0045926 | negative regulation of growth | 22.2222 | 4 | no |
GO:0048638 | regulation of developmental growth | 22.2222 | 4 | no |
GO:0048854 | brain morphogenesis | 22.2222 | 4 | no |
GO:0051050 | positive regulation of transport | 22.2222 | 4 | no |
GO:0071310 | cellular response to organic substance | 22.2222 | 4 | no |
GO:0071396 | cellular response to lipid | 22.2222 | 5 | no |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SKP1_HUMAN | [view interactions] | High throughput | no | yes |
SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
INSR_HUMAN | [view interactions] | High throughput | no | yes |
BMI1_HUMAN | [view interactions] | High throughput | no | yes |
ACK1_HUMAN | [view interactions] | High throughput | no | yes |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
FBX16_HUMAN | [view interactions] | Computational | no | no |