Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

FBX41_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in FBX41_HUMAN
GO:0043169 cation binding 35.7143 4 no
GO:0046872 metal ion binding 35.7143 5 no
GO:0000166 nucleotide binding 28.5714 4 no
GO:0005524 ATP binding 28.5714 5 no
GO:0016301 kinase activity 28.5714 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 28.5714 4 no
GO:0017076 purine nucleotide binding 28.5714 5 no
GO:0030554 adenyl nucleotide binding 28.5714 6 no
GO:0032555 purine ribonucleotide binding 28.5714 4 no
GO:0032559 adenyl ribonucleotide binding 28.5714 5 no
GO:0035639 purine ribonucleoside triphosphate binding 28.5714 4 no
GO:0043168 anion binding 28.5714 4 no
GO:0004674 protein serine/threonine kinase activity 21.4286 4 no
GO:0106310 protein serine kinase activity 21.4286 4 no
GO:0003779 actin binding 21.4286 4 no
GO:0019900 kinase binding 21.4286 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in FBX41_HUMAN
GO:0048522 positive regulation of cellular process 71.4286 4 no
GO:0051128 regulation of cellular component organization 64.2857 4 no
GO:0010646 regulation of cell communication 64.2857 4 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0009966 regulation of signal transduction 50.0000 4 no
GO:0048523 negative regulation of cellular process 50.0000 4 no
GO:0031323 regulation of cellular metabolic process 42.8571 4 no
GO:0051246 regulation of protein metabolic process 42.8571 5 no
GO:0080090 regulation of primary metabolic process 42.8571 4 no
GO:0141124 intracellular signaling cassette 42.8571 4 no
GO:0022603 regulation of anatomical structure morphogenesis 42.8571 4 no
GO:0030030 cell projection organization 42.8571 4 no
GO:0009893 positive regulation of metabolic process 35.7143 4 no
GO:0010604 positive regulation of macromolecule metabolic process 35.7143 5 no
GO:0019220 regulation of phosphate metabolic process 35.7143 6 no
GO:0031399 regulation of protein modification process 35.7143 6 no
GO:0051174 regulation of phosphorus metabolic process 35.7143 5 no
GO:0006996 organelle organization 35.7143 4 no
GO:0008104 protein localization 35.7143 4 no
GO:0010975 regulation of neuron projection development 35.7143 7 no
GO:0031344 regulation of cell projection organization 35.7143 5 no
GO:0045595 regulation of cell differentiation 35.7143 4 no
GO:0050804 modulation of chemical synaptic transmission 35.7143 5 no
GO:0050890 cognition 35.7143 4 no
GO:0099177 regulation of trans-synaptic signaling 35.7143 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 35.7143 6 no
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0006796 phosphate-containing compound metabolic process 28.5714 4 no
GO:0031325 positive regulation of cellular metabolic process 28.5714 5 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0051247 positive regulation of protein metabolic process 28.5714 6 no
GO:0007612 learning 28.5714 4 no
GO:0009967 positive regulation of signal transduction 28.5714 5 no
GO:0010647 positive regulation of cell communication 28.5714 5 no
GO:0022607 cellular component assembly 28.5714 4 no
GO:0023056 positive regulation of signaling 28.5714 4 no
GO:0033043 regulation of organelle organization 28.5714 5 no
GO:0034330 cell junction organization 28.5714 4 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 no
GO:0050767 regulation of neurogenesis 28.5714 6 no
GO:0050807 regulation of synapse organization 28.5714 5 no
GO:0051130 positive regulation of cellular component organization 28.5714 5 no
GO:0051960 regulation of nervous system development 28.5714 5 no
GO:0060284 regulation of cell development 28.5714 5 no
GO:0099175 regulation of postsynapse organization 28.5714 6 no
GO:0120036 plasma membrane bounded cell projection organization 28.5714 5 no
GO:2000026 regulation of multicellular organismal development 28.5714 4 no
GO:0036211 protein modification process 28.5714 4 no
GO:0043412 macromolecule modification 28.5714 4 no
GO:0001558 regulation of cell growth 28.5714 4 no
GO:0043085 positive regulation of catalytic activity 28.5714 4 no
GO:1902531 regulation of intracellular signal transduction 28.5714 5 no
GO:0010243 response to organonitrogen compound 28.5714 4 no
GO:0042127 regulation of cell population proliferation 28.5714 4 no
GO:0051726 regulation of cell cycle 28.5714 4 no
GO:0001934 positive regulation of protein phosphorylation 21.4286 8 no
GO:0010562 positive regulation of phosphorus metabolic process 21.4286 6 no
GO:0016310 phosphorylation 21.4286 5 no
GO:0031401 positive regulation of protein modification process 21.4286 7 no
GO:0042327 positive regulation of phosphorylation 21.4286 8 no
GO:0045937 positive regulation of phosphate metabolic process 21.4286 7 no
GO:0051049 regulation of transport 21.4286 4 no
GO:0000165 MAPK cascade 21.4286 5 no
GO:0010720 positive regulation of cell development 21.4286 6 no
GO:0031175 neuron projection development 21.4286 6 no
GO:0032956 regulation of actin cytoskeleton organization 21.4286 5 no
GO:0032970 regulation of actin filament-based process 21.4286 4 no
GO:0044087 regulation of cellular component biogenesis 21.4286 4 no
GO:0045597 positive regulation of cell differentiation 21.4286 5 no
GO:0048812 neuron projection morphogenesis 21.4286 5 no
GO:0050769 positive regulation of neurogenesis 21.4286 6 no
GO:0050808 synapse organization 21.4286 5 no
GO:0051094 positive regulation of developmental process 21.4286 4 no
GO:0051240 positive regulation of multicellular organismal process 21.4286 4 no
GO:0051493 regulation of cytoskeleton organization 21.4286 6 no
GO:0051962 positive regulation of nervous system development 21.4286 5 no
GO:0060998 regulation of dendritic spine development 21.4286 4 no
GO:0072657 protein localization to membrane 21.4286 4 no
GO:0120039 plasma membrane bounded cell projection morphogenesis 21.4286 4 no
GO:0048638 regulation of developmental growth 21.4286 4 no
GO:0050770 regulation of axonogenesis 21.4286 5 no
GO:0010648 negative regulation of cell communication 21.4286 5 no
GO:0023057 negative regulation of signaling 21.4286 4 no
GO:0014070 response to organic cyclic compound 21.4286 4 no
GO:0033993 response to lipid 21.4286 4 no
GO:0007010 cytoskeleton organization 21.4286 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SKP1_HUMAN [view interactions] Low throughput no yes
SKP2_HUMAN [view interactions] Low throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP1_HUMAN [view entry] [view interactions] High throughput yes no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
BMI1_HUMAN [view interactions] High throughput no yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
ACK1_HUMAN [view entry] [view interactions] High throughput yes yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
TRIM9_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
STK11_HUMAN [view interactions] High throughput no yes
OTUD4_HUMAN [view interactions] High throughput no yes
CDKL5_HUMAN [view entry] [view interactions] High throughput yes yes
PPP5_HUMAN [view entry] [view interactions] High throughput yes yes
PTK7_HUMAN [view interactions] High throughput no yes
TAOK2_HUMAN [view entry] [view interactions] High throughput yes yes