Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CK2N1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Potent and specific inhibitor of CaM-kinase II (CAMK2). [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CK2N1_HUMAN
GO:0042803 protein homodimerization activity 71.4286 4 no
GO:0000166 nucleotide binding 57.1429 4 no
GO:0004674 protein serine/threonine kinase activity 57.1429 4 no
GO:0004683 calmodulin-dependent protein kinase activity 57.1429 5 no
GO:0005524 ATP binding 57.1429 5 no
GO:0016301 kinase activity 57.1429 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 57.1429 4 no
GO:0017076 purine nucleotide binding 57.1429 5 no
GO:0030554 adenyl nucleotide binding 57.1429 6 no
GO:0032555 purine ribonucleotide binding 57.1429 4 no
GO:0032559 adenyl ribonucleotide binding 57.1429 5 no
GO:0035639 purine ribonucleoside triphosphate binding 57.1429 4 no
GO:0043168 anion binding 57.1429 4 no
GO:0106310 protein serine kinase activity 57.1429 4 no
GO:0019900 kinase binding 28.5714 4 yes
GO:0019901 protein kinase binding 28.5714 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in CK2N1_HUMAN
GO:0006796 phosphate-containing compound metabolic process 57.1429 4 no
GO:0010646 regulation of cell communication 57.1429 4 no
GO:0010959 regulation of metal ion transport 57.1429 6 no
GO:0016310 phosphorylation 57.1429 5 no
GO:0043269 regulation of monoatomic ion transport 57.1429 5 no
GO:0048522 positive regulation of cellular process 57.1429 4 no
GO:0051049 regulation of transport 57.1429 4 no
GO:0051924 regulation of calcium ion transport 57.1429 7 no
GO:0006468 protein phosphorylation 42.8571 5 no
GO:0018105 peptidyl-serine phosphorylation 42.8571 6 no
GO:0018193 peptidyl-amino acid modification 42.8571 5 no
GO:0018209 peptidyl-serine modification 42.8571 6 no
GO:0036211 protein modification process 42.8571 4 no
GO:0043412 macromolecule modification 42.8571 4 no
GO:0043502 regulation of muscle adaptation 42.8571 4 no
GO:0044057 regulation of system process 42.8571 4 no
GO:0046777 protein autophosphorylation 42.8571 6 no
GO:0050804 modulation of chemical synaptic transmission 42.8571 5 no
GO:0051128 regulation of cellular component organization 42.8571 4 no
GO:0090257 regulation of muscle system process 42.8571 5 no
GO:0099177 regulation of trans-synaptic signaling 42.8571 4 no
GO:0009889 regulation of biosynthetic process 42.8571 4 no
GO:0010468 regulation of gene expression 42.8571 6 no
GO:0010556 regulation of macromolecule biosynthetic process 42.8571 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 42.8571 5 no
GO:0031323 regulation of cellular metabolic process 42.8571 4 no
GO:0031326 regulation of cellular biosynthetic process 42.8571 5 no
GO:0051252 regulation of RNA metabolic process 42.8571 5 no
GO:0060255 regulation of macromolecule metabolic process 42.8571 4 no
GO:0080090 regulation of primary metabolic process 42.8571 4 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 yes
GO:0007399 nervous system development 28.5714 4 no
GO:0010975 regulation of neuron projection development 28.5714 7 no
GO:0014733 regulation of skeletal muscle adaptation 28.5714 5 no
GO:0030334 regulation of cell migration 28.5714 5 no
GO:0031344 regulation of cell projection organization 28.5714 5 no
GO:0048168 regulation of neuronal synaptic plasticity 28.5714 4 no
GO:0051240 positive regulation of multicellular organismal process 28.5714 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 28.5714 6 no
GO:2000145 regulation of cell motility 28.5714 4 no
GO:2001222 regulation of neuron migration 28.5714 6 no
GO:0008104 protein localization 28.5714 4 no
GO:0015031 protein transport 28.5714 4 no
GO:0048523 negative regulation of cellular process 28.5714 4 no
GO:0071702 organic substance transport 28.5714 4 no
GO:0071705 nitrogen compound transport 28.5714 4 no
GO:0006355 regulation of DNA-templated transcription 28.5714 7 no
GO:0006811 monoatomic ion transport 28.5714 4 no
GO:0010660 regulation of muscle cell apoptotic process 28.5714 6 no
GO:0010661 positive regulation of muscle cell apoptotic process 28.5714 7 no
GO:0010662 regulation of striated muscle cell apoptotic process 28.5714 7 no
GO:0010663 positive regulation of striated muscle cell apoptotic process 28.5714 8 no
GO:0010665 regulation of cardiac muscle cell apoptotic process 28.5714 8 no
GO:0010666 positive regulation of cardiac muscle cell apoptotic process 28.5714 9 no
GO:0018107 peptidyl-threonine phosphorylation 28.5714 6 no
GO:0018210 peptidyl-threonine modification 28.5714 6 no
GO:0042981 regulation of apoptotic process 28.5714 5 no
GO:0043065 positive regulation of apoptotic process 28.5714 6 no
GO:0043067 regulation of programmed cell death 28.5714 4 no
GO:0043068 positive regulation of programmed cell death 28.5714 5 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GBRR1_HUMAN [view entry] [view interactions] Low throughput yes no
KCC2G_HUMAN [view entry] [view interactions] High throughput yes yes
KCC2D_HUMAN [view entry] [view interactions] High throughput yes yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPL_HUMAN [view interactions] High throughput no yes
DX39A_HUMAN [view interactions] High throughput no yes
KCC2B_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no