CNKR2_HUMAN
Evidence for PS localization
Functions
May function as an adapter protein or regulator of Ras signaling pathways. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CNKR2_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 33.9286 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 33.9286 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 33.9286 | 4 | no |
| GO:0046872 | metal ion binding | 28.5714 | 4 | no |
| GO:0019900 | kinase binding | 26.7857 | 4 | yes |
| GO:0005524 | ATP binding | 23.2143 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 23.2143 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 23.2143 | 5 | no |
| GO:0019901 | protein kinase binding | 21.4286 | 5 | yes |
| GO:0016301 | kinase activity | 21.4286 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CNKR2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 62.5000 | 4 | no |
| GO:0010646 | regulation of cell communication | 60.7143 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 53.5714 | 4 | no |
| GO:0009966 | regulation of signal transduction | 51.7857 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | no |
| GO:0006996 | organelle organization | 42.8571 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 37.5000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 35.7143 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 35.7143 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 35.7143 | 4 | no |
| GO:0008104 | protein localization | 32.1429 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 32.1429 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 30.3571 | 5 | no |
| GO:0007010 | cytoskeleton organization | 28.5714 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 28.5714 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 28.5714 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 28.5714 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 28.5714 | 5 | no |
| GO:0023056 | positive regulation of signaling | 28.5714 | 4 | no |
| GO:0043412 | macromolecule modification | 28.5714 | 4 | no |
| GO:0051049 | regulation of transport | 28.5714 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 28.5714 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 28.5714 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 26.7857 | 5 | no |
| GO:0036211 | protein modification process | 26.7857 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 26.7857 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 26.7857 | 4 | no |
| GO:0022607 | cellular component assembly | 26.7857 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 26.7857 | 6 | no |
| GO:0033043 | regulation of organelle organization | 25.0000 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 25.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 25.0000 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 23.2143 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 23.2143 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.2143 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 23.2143 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 23.2143 | 5 | no |
| GO:0010941 | regulation of cell death | 23.2143 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 23.2143 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 23.2143 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.2143 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 21.4286 | 5 | no |
| GO:0016310 | phosphorylation | 21.4286 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 21.4286 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 21.4286 | 5 | no |
| GO:2000026 | regulation of multicellular organismal development | 21.4286 | 4 | no |
| GO:0010975 | regulation of neuron projection development | 21.4286 | 7 | no |
| GO:0016192 | vesicle-mediated transport | 21.4286 | 4 | no |
| GO:0099173 | postsynapse organization | 10.7143 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LRRC7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CNKR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RALA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RLF_HUMAN | [view interactions] | Low throughput | no | no |
| SMUF2_HUMAN | [view interactions] | Low throughput | no | yes |
| NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP3_HUMAN | [view interactions] | High throughput | no | no |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| MOB3B_HUMAN | [view interactions] | High throughput | no | no |
| ENSA_HUMAN | [view interactions] | High throughput | no | yes |
| RHEB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP180_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TENR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRIG2_HUMAN | [view interactions] | High throughput | no | yes |
| IQEC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AINX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRM4_HUMAN | [view interactions] | High throughput | no | no |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYH3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYH1_HUMAN | [view interactions] | High throughput | no | no |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| CSN6_HUMAN | [view interactions] | High throughput | no | yes |
| TNAP3_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KALRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| DLGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PEBP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SAM12_HUMAN | [view interactions] | Computational | no | yes |
| KSR1_HUMAN | [view interactions] | Computational | no | yes |
| RASN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | Computational | yes | no |