STRN_HUMAN
Evidence for PS localization
Functions
Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002046 | DOC_ANK_TNKS_1 | DOC | 301 | 308 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in STRN_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 32.3077 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 32.3077 | 5 | no |
| GO:0005524 | ATP binding | 30.7692 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 30.7692 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 30.7692 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 30.7692 | 4 | no |
| GO:0019900 | kinase binding | 21.5385 | 4 | no |
| GO:0019901 | protein kinase binding | 21.5385 | 5 | no |
| GO:0003723 | RNA binding | 21.5385 | 4 | no |
| GO:0140297 | DNA-binding transcription factor binding | 6.1538 | 4 | yes |
| GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding | 4.6154 | 5 | yes |
| GO:0016922 | nuclear receptor binding | 3.0769 | 6 | yes |
| GO:0019902 | phosphatase binding | 3.0769 | 4 | yes |
| GO:0019903 | protein phosphatase binding | 3.0769 | 5 | yes |
| GO:0030331 | nuclear estrogen receptor binding | 3.0769 | 7 | yes |
| GO:0051721 | protein phosphatase 2A binding | 3.0769 | 6 | yes |
| GO:0070016 | armadillo repeat domain binding | 3.0769 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in STRN_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 66.1538 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 60.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 56.9231 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 55.3846 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 55.3846 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 50.7692 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 50.7692 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 47.6923 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 46.1538 | 5 | no |
| GO:0022607 | cellular component assembly | 40.0000 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 40.0000 | 5 | no |
| GO:0010646 | regulation of cell communication | 38.4615 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 38.4615 | 5 | no |
| GO:0006996 | organelle organization | 38.4615 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 36.9231 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 36.9231 | 4 | no |
| GO:0009966 | regulation of signal transduction | 36.9231 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 36.9231 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 36.9231 | 5 | no |
| GO:0008104 | protein localization | 36.9231 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 35.3846 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.3077 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.3077 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 32.3077 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.2308 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 29.2308 | 6 | no |
| GO:0033043 | regulation of organelle organization | 29.2308 | 5 | no |
| GO:0010468 | regulation of gene expression | 27.6923 | 5 | no |
| GO:0051049 | regulation of transport | 27.6923 | 4 | no |
| GO:0036211 | protein modification process | 26.1538 | 4 | no |
| GO:0043412 | macromolecule modification | 26.1538 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.1538 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.1538 | 5 | no |
| GO:0010941 | regulation of cell death | 26.1538 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 26.1538 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 26.1538 | 5 | no |
| GO:0031399 | regulation of protein modification process | 24.6154 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 24.6154 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 24.6154 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 24.6154 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.0769 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 23.0769 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.0769 | 5 | no |
| GO:0009894 | regulation of catabolic process | 23.0769 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.0769 | 6 | no |
| GO:0015031 | protein transport | 23.0769 | 4 | no |
| GO:0060341 | regulation of cellular localization | 23.0769 | 4 | no |
| GO:0071702 | organic substance transport | 23.0769 | 4 | no |
| GO:0071705 | nitrogen compound transport | 23.0769 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 21.5385 | 7 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 21.5385 | 4 | no |
| GO:0051338 | regulation of transferase activity | 21.5385 | 4 | no |
| GO:0032880 | regulation of protein localization | 21.5385 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 21.5385 | 4 | no |
| GO:0030030 | cell projection organization | 16.9231 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 15.3846 | 5 | yes |
| GO:0042127 | regulation of cell population proliferation | 10.7692 | 4 | yes |
| GO:0034330 | cell junction organization | 9.2308 | 4 | yes |
| GO:0016055 | Wnt signaling pathway | 7.6923 | 5 | yes |
| GO:0034329 | cell junction assembly | 7.6923 | 5 | yes |
| GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 7.6923 | 4 | yes |
| GO:0031175 | neuron projection development | 6.1538 | 6 | yes |
| GO:0045216 | cell-cell junction organization | 6.1538 | 5 | yes |
| GO:0007043 | cell-cell junction assembly | 4.6154 | 6 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 3.0769 | 5 | yes |
| GO:0070830 | bicellular tight junction assembly | 3.0769 | 8 | yes |
| GO:0120192 | tight junction assembly | 3.0769 | 7 | yes |
| GO:0120193 | tight junction organization | 3.0769 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in STRN_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 3.0769 | 3 | no |
| DOID:0050700 | cardiomyopathy | 3.0769 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 3.0769 | 5 | no |
| DOID:114 | heart disease | 3.0769 | 3 | no |
| DOID:2843 | long QT syndrome | 3.0769 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CAV1_HUMAN | [view interactions] | Low throughput | no | no |
| APC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ZO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TNKS2_HUMAN | [view interactions] | Low throughput | no | no |
| RASF3_HUMAN | [view interactions] | High throughput | no | yes |
| PGAM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PP2AB_HUMAN | [view interactions] | High throughput | no | yes |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AHNK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S43A3_HUMAN | [view interactions] | High throughput | no | yes |
| MCA3_HUMAN | [view interactions] | High throughput | no | yes |
| ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN550_HUMAN | [view interactions] | High throughput | no | yes |
| LYPD3_HUMAN | [view interactions] | High throughput | no | no |
| PRS8_HUMAN | [view interactions] | High throughput | no | yes |
| ZN331_HUMAN | [view interactions] | High throughput | no | no |
| PRD14_HUMAN | [view interactions] | High throughput | no | no |
| ISK2_HUMAN | [view interactions] | High throughput | no | no |
| PRP19_HUMAN | [view interactions] | High throughput | no | yes |
| NHSL2_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK3_HUMAN | [view interactions] | High throughput | no | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RINT1_HUMAN | [view interactions] | High throughput | no | yes |
| TFP11_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SCHI1_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TUFT1_HUMAN | [view interactions] | High throughput | no | no |
| GOGA5_HUMAN | [view interactions] | High throughput | no | yes |
| NCK5L_HUMAN | [view interactions] | High throughput | no | yes |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| TFPT_HUMAN | [view interactions] | High throughput | no | yes |
| YETS4_HUMAN | [view interactions] | High throughput | no | no |
| RBG1L_HUMAN | [view interactions] | High throughput | no | yes |
| PKN3_HUMAN | [view interactions] | High throughput | no | yes |
| LNX1_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| PAXI1_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCOC2_HUMAN | [view interactions] | High throughput | no | no |
| NR1H3_HUMAN | [view interactions] | High throughput | no | yes |
| 2ABG_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| M4K4_HUMAN | [view interactions] | High throughput | no | yes |
| TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
| MYPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX24_HUMAN | [view interactions] | High throughput | no | yes |
| LRCC1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKT3_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
| DYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PMF1_HUMAN | [view interactions] | High throughput | no | no |
| RABE2_HUMAN | [view interactions] | High throughput | no | yes |
| ENDD1_HUMAN | [view interactions] | High throughput | no | yes |
| FLII_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1522_HUMAN | [view interactions] | High throughput | no | yes |
| ISCA2_HUMAN | [view interactions] | High throughput | no | yes |
| GOG6A_HUMAN | [view interactions] | High throughput | no | no |
| FLIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SSUH2_HUMAN | [view interactions] | High throughput | no | no |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| MAP1S_HUMAN | [view interactions] | High throughput | no | no |
| PSA5_HUMAN | [view interactions] | High throughput | no | yes |
| CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CPSF6_HUMAN | [view interactions] | High throughput | no | yes |
| IF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3B5_HUMAN | [view interactions] | High throughput | no | yes |
| BABA1_HUMAN | [view interactions] | High throughput | no | yes |
| SHLB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 4EBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RABX5_HUMAN | [view interactions] | High throughput | no | no |
| RGPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMD3_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| NBEA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAB_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STRP1_HUMAN | [view interactions] | High throughput | no | yes |
| CT2NL_HUMAN | [view interactions] | High throughput | no | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN3_HUMAN | [view interactions] | High throughput | no | yes |
| PHOCN_HUMAN | [view interactions] | High throughput | no | yes |
| STK24_HUMAN | [view interactions] | High throughput | no | yes |
| STK25_HUMAN | [view interactions] | High throughput | no | no |
| PDC10_HUMAN | [view interactions] | High throughput | no | yes |
| T3JAM_HUMAN | [view interactions] | High throughput | no | no |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGOP2_HUMAN | [view interactions] | High throughput | no | yes |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIKE1_HUMAN | [view interactions] | High throughput | no | yes |
| STRP2_HUMAN | [view interactions] | High throughput | no | yes |
| STK26_HUMAN | [view interactions] | High throughput | no | no |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLMAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPW_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| STK4_HUMAN | [view interactions] | High throughput | no | yes |
| SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SUOX_HUMAN | [view interactions] | Computational | no | no |
| AKT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PTPA_HUMAN | [view interactions] | Computational | no | yes |
| 2A5B_HUMAN | [view interactions] | Computational | no | yes |