CTTB2_HUMAN
Evidence for PS localization
Functions
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CTTB2_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 35.1351 | 4 | no |
| GO:0017076 | purine nucleotide binding | 35.1351 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 35.1351 | 4 | no |
| GO:0043168 | anion binding | 35.1351 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 32.4324 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 29.7297 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 29.7297 | 5 | no |
| GO:0005524 | ATP binding | 27.0270 | 5 | no |
| GO:0016462 | pyrophosphatase activity | 24.3243 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 24.3243 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 24.3243 | 6 | no |
| GO:0017124 | SH3 domain binding | 8.1081 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CTTB2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 70.2703 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 59.4595 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 56.7568 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 51.3514 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.6486 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 45.9459 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 45.9459 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 45.9459 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 45.9459 | 4 | no |
| GO:0010646 | regulation of cell communication | 43.2432 | 4 | no |
| GO:0022607 | cellular component assembly | 43.2432 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 43.2432 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 40.5405 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 40.5405 | 5 | no |
| GO:0009966 | regulation of signal transduction | 37.8378 | 4 | no |
| GO:0006996 | organelle organization | 35.1351 | 4 | no |
| GO:0033043 | regulation of organelle organization | 35.1351 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 35.1351 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 32.4324 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 32.4324 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 32.4324 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 32.4324 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 27.0270 | 5 | no |
| GO:0023056 | positive regulation of signaling | 27.0270 | 4 | no |
| GO:0030030 | cell projection organization | 27.0270 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 27.0270 | 5 | no |
| GO:0032880 | regulation of protein localization | 27.0270 | 5 | no |
| GO:0060341 | regulation of cellular localization | 27.0270 | 4 | no |
| GO:0007010 | cytoskeleton organization | 24.3243 | 5 | no |
| GO:0008104 | protein localization | 24.3243 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.3243 | 6 | no |
| GO:0031399 | regulation of protein modification process | 24.3243 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 24.3243 | 7 | no |
| GO:0048584 | positive regulation of response to stimulus | 24.3243 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.3243 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 24.3243 | 5 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 24.3243 | 5 | no |
| GO:0051052 | regulation of DNA metabolic process | 24.3243 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 24.3243 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 21.6216 | 7 | no |
| GO:0009967 | positive regulation of signal transduction | 21.6216 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.6216 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 21.6216 | 5 | no |
| GO:0010638 | positive regulation of organelle organization | 21.6216 | 6 | no |
| GO:0070201 | regulation of establishment of protein localization | 21.6216 | 6 | no |
| GO:1903829 | positive regulation of protein localization | 21.6216 | 5 | no |
| GO:1904951 | positive regulation of establishment of protein localization | 21.6216 | 6 | no |
| GO:0010468 | regulation of gene expression | 21.6216 | 6 | no |
| GO:0034330 | cell junction organization | 21.6216 | 4 | no |
| GO:0050807 | regulation of synapse organization | 10.8108 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SHAN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SHAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| STRN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK25_HUMAN | [view interactions] | High throughput | no | no |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STK24_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PRD14_HUMAN | [view interactions] | High throughput | no | no |
| PP2AB_HUMAN | [view interactions] | High throughput | no | yes |
| PLEC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGAB_HUMAN | [view interactions] | High throughput | no | no |
| HSF2B_HUMAN | [view interactions] | High throughput | no | yes |
| K1C14_HUMAN | [view interactions] | High throughput | no | no |
| MEI4_HUMAN | [view interactions] | High throughput | no | no |
| PKNX2_HUMAN | [view interactions] | High throughput | no | yes |
| INCA1_HUMAN | [view interactions] | High throughput | no | no |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMAL2_HUMAN | [view interactions] | High throughput | no | yes |
| F86C1_HUMAN | [view interactions] | High throughput | no | no |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CC136_HUMAN | [view interactions] | High throughput | no | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M4K4_HUMAN | [view interactions] | High throughput | no | yes |
| VATG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CHIO_HUMAN | [view interactions] | High throughput | no | yes |
| IGBP1_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIPA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPME1_HUMAN | [view interactions] | High throughput | no | yes |
| 2ABA_HUMAN | [view interactions] | High throughput | no | yes |
| RUFY3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2ABD_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHOCN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRP2_HUMAN | [view interactions] | High throughput | no | yes |
| CT2NL_HUMAN | [view interactions] | High throughput | no | yes |
| STRN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDC10_HUMAN | [view interactions] | High throughput | no | yes |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRP1_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAB_HUMAN | [view interactions] | High throughput | no | yes |
| STK26_HUMAN | [view interactions] | High throughput | no | no |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |