Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CTTB2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CTTB2_HUMAN
GO:0017076 purine nucleotide binding 36.3636 4 no
GO:0032555 purine ribonucleotide binding 36.3636 4 no
GO:0030554 adenyl nucleotide binding 33.3333 5 no
GO:0032559 adenyl ribonucleotide binding 33.3333 5 no
GO:0035639 purine ribonucleoside triphosphate binding 33.3333 4 no
GO:0005524 ATP binding 30.3030 5 no
GO:0016462 pyrophosphatase activity 24.2424 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 24.2424 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 24.2424 6 no
GO:0016887 ATP hydrolysis activity 21.2121 7 no
GO:0017124 SH3 domain binding 9.0909 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in CTTB2_HUMAN
GO:0048522 positive regulation of cellular process 69.6970 4 no
GO:0031323 regulation of cellular metabolic process 66.6667 4 no
GO:0060255 regulation of macromolecule metabolic process 60.6061 4 no
GO:0051128 regulation of cellular component organization 57.5758 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 57.5758 4 no
GO:0080090 regulation of primary metabolic process 57.5758 4 no
GO:0009893 positive regulation of metabolic process 48.4848 4 no
GO:0010604 positive regulation of macromolecule metabolic process 48.4848 5 no
GO:0022607 cellular component assembly 48.4848 4 no
GO:0031325 positive regulation of cellular metabolic process 45.4545 5 no
GO:0048523 negative regulation of cellular process 45.4545 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 45.4545 5 no
GO:0009889 regulation of biosynthetic process 42.4242 4 no
GO:0010646 regulation of cell communication 42.4242 4 no
GO:0031326 regulation of cellular biosynthetic process 42.4242 5 no
GO:0009966 regulation of signal transduction 39.3939 4 no
GO:0006996 organelle organization 39.3939 4 no
GO:0010556 regulation of macromolecule biosynthetic process 36.3636 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 36.3636 5 no
GO:0051246 regulation of protein metabolic process 33.3333 5 no
GO:0051130 positive regulation of cellular component organization 33.3333 5 no
GO:0033043 regulation of organelle organization 33.3333 5 no
GO:0019220 regulation of phosphate metabolic process 30.3030 6 no
GO:0031399 regulation of protein modification process 30.3030 6 no
GO:0042325 regulation of phosphorylation 30.3030 7 no
GO:0051174 regulation of phosphorus metabolic process 30.3030 5 no
GO:0008104 protein localization 30.3030 4 no
GO:0032880 regulation of protein localization 30.3030 5 no
GO:0060341 regulation of cellular localization 30.3030 4 no
GO:0030030 cell projection organization 30.3030 4 no
GO:0001932 regulation of protein phosphorylation 27.2727 7 no
GO:0051052 regulation of DNA metabolic process 27.2727 5 no
GO:0009891 positive regulation of biosynthetic process 27.2727 5 no
GO:0031328 positive regulation of cellular biosynthetic process 27.2727 6 no
GO:0120036 plasma membrane bounded cell projection organization 27.2727 5 no
GO:0043085 positive regulation of catalytic activity 24.2424 4 no
GO:0045595 regulation of cell differentiation 24.2424 4 no
GO:0051247 positive regulation of protein metabolic process 24.2424 6 no
GO:0051338 regulation of transferase activity 24.2424 4 no
GO:1902531 regulation of intracellular signal transduction 24.2424 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 24.2424 6 no
GO:0043933 protein-containing complex organization 24.2424 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 24.2424 6 no
GO:0070201 regulation of establishment of protein localization 24.2424 6 no
GO:0048584 positive regulation of response to stimulus 24.2424 4 no
GO:0007010 cytoskeleton organization 24.2424 5 no
GO:0009892 negative regulation of metabolic process 21.2121 4 no
GO:0010468 regulation of gene expression 21.2121 5 no
GO:0031324 negative regulation of cellular metabolic process 21.2121 5 no
GO:0031401 positive regulation of protein modification process 21.2121 7 no
GO:0036211 protein modification process 21.2121 4 no
GO:0043412 macromolecule modification 21.2121 4 no
GO:0010638 positive regulation of organelle organization 21.2121 6 no
GO:0051054 positive regulation of DNA metabolic process 21.2121 6 no
GO:0065003 protein-containing complex assembly 21.2121 5 no
GO:1903829 positive regulation of protein localization 21.2121 5 no
GO:1904951 positive regulation of establishment of protein localization 21.2121 6 no
GO:0009967 positive regulation of signal transduction 21.2121 5 no
GO:0010647 positive regulation of cell communication 21.2121 5 no
GO:0023056 positive regulation of signaling 21.2121 4 no
GO:0050807 regulation of synapse organization 9.0909 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DYL1_HUMAN [view entry] [view interactions] High throughput yes no
SRC8_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
CHIO_HUMAN [view interactions] High throughput no yes
IGBP1_HUMAN [view interactions] High throughput no yes
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
LIPA3_HUMAN [view entry] [view interactions] High throughput yes yes
PPME1_HUMAN [view interactions] High throughput no yes
2ABA_HUMAN [view interactions] High throughput no yes
RUFY3_HUMAN [view entry] [view interactions] High throughput yes yes
2ABD_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
MARE3_HUMAN [view entry] [view interactions] High throughput yes yes
CRK_HUMAN [view entry] [view interactions] High throughput yes no
PHOCN_HUMAN [view interactions] High throughput no yes
PP2AA_HUMAN [view entry] [view interactions] High throughput yes yes
STRN_HUMAN [view entry] [view interactions] High throughput yes yes
STRN3_HUMAN [view interactions] High throughput no yes
STK24_HUMAN [view interactions] High throughput no yes
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
STK25_HUMAN [view interactions] High throughput no no
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
STK26_HUMAN [view interactions] High throughput no no
2AAB_HUMAN [view interactions] High throughput no yes
STRP1_HUMAN [view interactions] High throughput no yes
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
PDC10_HUMAN [view interactions] High throughput no yes
STRN4_HUMAN [view entry] [view interactions] High throughput yes yes
CT2NL_HUMAN [view interactions] High throughput no yes
STRP2_HUMAN [view interactions] High throughput no yes
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
PRD14_HUMAN [view interactions] High throughput no no
PP2AB_HUMAN [view interactions] High throughput no yes
PLEC_HUMAN [view entry] [view interactions] High throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
CYFP2_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
TRIO_HUMAN [view entry] [view interactions] High throughput yes yes
MAGAB_HUMAN [view interactions] High throughput no no
HSF2B_HUMAN [view interactions] High throughput no yes
K1C14_HUMAN [view interactions] High throughput no no
MEI4_HUMAN [view interactions] High throughput no no
PKNX2_HUMAN [view interactions] High throughput no yes
INCA1_HUMAN [view interactions] High throughput no no
DP13A_HUMAN [view entry] [view interactions] High throughput yes yes
BMAL2_HUMAN [view interactions] High throughput no yes
F86C1_HUMAN [view interactions] High throughput no no
RAD21_HUMAN [view interactions] High throughput no yes
RPGF2_HUMAN [view entry] [view interactions] High throughput yes no
LNX1_HUMAN [view interactions] High throughput no yes
CC136_HUMAN [view interactions] High throughput no yes
SPDLY_HUMAN [view interactions] High throughput no yes
UBP15_HUMAN [view entry] [view interactions] High throughput yes yes
VIR_HUMAN [view interactions] High throughput no yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
M4K4_HUMAN [view interactions] High throughput no yes
VATG1_HUMAN [view entry] [view interactions] High throughput yes yes
DYL2_HUMAN [view entry] [view interactions] High throughput yes no
CWC15_HUMAN [view interactions] Computational no yes