EEA1_HUMAN
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in EEA1_HUMAN |
---|---|---|---|---|
GO:0000166 | nucleotide binding | 33.8710 | 4 | no |
GO:0017076 | purine nucleotide binding | 33.8710 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 32.2581 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 32.2581 | 4 | no |
GO:0043168 | anion binding | 32.2581 | 4 | no |
GO:0043169 | cation binding | 25.8065 | 4 | yes |
GO:0046872 | metal ion binding | 24.1935 | 5 | yes |
GO:0030554 | adenyl nucleotide binding | 22.5806 | 6 | no |
GO:0005524 | ATP binding | 20.9677 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 20.9677 | 5 | no |
GO:0042803 | protein homodimerization activity | 14.5161 | 4 | yes |
GO:0046914 | transition metal ion binding | 12.9032 | 6 | yes |
GO:0008270 | zinc ion binding | 11.2903 | 7 | yes |
GO:0035091 | phosphatidylinositol binding | 8.0645 | 4 | yes |
GO:0005545 | 1-phosphatidylinositol binding | 3.2258 | 5 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in EEA1_HUMAN |
---|---|---|---|---|
GO:0008104 | protein localization | 51.6129 | 4 | no |
GO:0006996 | organelle organization | 48.3871 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 48.3871 | 4 | no |
GO:0051128 | regulation of cellular component organization | 45.1613 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 43.5484 | 4 | no |
GO:0071702 | organic substance transport | 40.3226 | 4 | no |
GO:0071705 | nitrogen compound transport | 40.3226 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 38.7097 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 38.7097 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 38.7097 | 5 | no |
GO:0080090 | regulation of primary metabolic process | 38.7097 | 4 | no |
GO:0015031 | protein transport | 38.7097 | 4 | no |
GO:0010646 | regulation of cell communication | 33.8710 | 4 | no |
GO:0051049 | regulation of transport | 32.2581 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 32.2581 | 4 | no |
GO:0006886 | intracellular protein transport | 32.2581 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 30.6452 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 30.6452 | 5 | no |
GO:0048523 | negative regulation of cellular process | 30.6452 | 4 | no |
GO:0009966 | regulation of signal transduction | 29.0323 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 29.0323 | 5 | no |
GO:0022607 | cellular component assembly | 29.0323 | 4 | no |
GO:0023056 | positive regulation of signaling | 29.0323 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 29.0323 | 5 | no |
GO:0010468 | regulation of gene expression | 27.4194 | 6 | no |
GO:0010647 | positive regulation of cell communication | 27.4194 | 5 | no |
GO:0036211 | protein modification process | 27.4194 | 4 | no |
GO:0043412 | macromolecule modification | 27.4194 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 27.4194 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 27.4194 | 6 | no |
GO:0009891 | positive regulation of biosynthetic process | 25.8065 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 25.8065 | 5 | no |
GO:0032880 | regulation of protein localization | 25.8065 | 5 | no |
GO:0060341 | regulation of cellular localization | 25.8065 | 4 | no |
GO:0016050 | vesicle organization | 24.1935 | 5 | yes |
GO:0031328 | positive regulation of cellular biosynthetic process | 24.1935 | 6 | no |
GO:0060627 | regulation of vesicle-mediated transport | 22.5806 | 4 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.5806 | 6 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.5806 | 5 | no |
GO:0031399 | regulation of protein modification process | 22.5806 | 6 | no |
GO:0051130 | positive regulation of cellular component organization | 22.5806 | 5 | no |
GO:0098657 | import into cell | 20.9677 | 4 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 20.9677 | 4 | no |
GO:0031401 | positive regulation of protein modification process | 20.9677 | 7 | no |
GO:0033043 | regulation of organelle organization | 20.9677 | 5 | no |
GO:0043933 | protein-containing complex organization | 20.9677 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 20.9677 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 20.9677 | 5 | no |
GO:0061024 | membrane organization | 19.3548 | 4 | yes |
GO:0061025 | membrane fusion | 14.5161 | 5 | yes |
GO:0007032 | endosome organization | 12.9032 | 6 | yes |
GO:0006906 | vesicle fusion | 11.2903 | 6 | yes |
GO:0048284 | organelle fusion | 11.2903 | 5 | yes |
GO:0090174 | organelle membrane fusion | 11.2903 | 6 | yes |
GO:0044788 | modulation by host of viral process | 6.4516 | 5 | yes |
GO:0045022 | early endosome to late endosome transport | 6.4516 | 5 | yes |
GO:0051851 | modulation by host of symbiont process | 6.4516 | 4 | yes |
GO:0098927 | vesicle-mediated transport between endosomal compartments | 6.4516 | 4 | yes |
GO:0016189 | synaptic vesicle to endosome fusion | 3.2258 | 6 | yes |
GO:0099565 | chemical synaptic transmission, postsynaptic | 3.2258 | 4 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
TOM1_HUMAN | [view interactions] | Low throughput | no | yes |
CY24B_HUMAN | [view interactions] | Low throughput | no | no |
ITB2_HUMAN | [view interactions] | Low throughput | no | no |
RASF5_HUMAN | [view interactions] | Low throughput | no | yes |
STK4_HUMAN | [view interactions] | Low throughput | no | yes |
VGFR2_HUMAN | [view interactions] | Low throughput | no | no |
VGFR1_HUMAN | [view interactions] | Low throughput | no | no |
SNX27_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RABE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TERA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
P53_HUMAN | [view interactions] | Low throughput | no | no |
STX12_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RAD_HUMAN | [view interactions] | Low throughput | no | yes |
PXK_HUMAN | [view interactions] | Low throughput | no | yes |
ACK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
WASH1_HUMAN | [view interactions] | Low throughput | no | yes |
VPS35_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBP8_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
1433S_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PROM1_HUMAN | [view interactions] | Low throughput | no | no |
MBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MYPR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ADRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NSF_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PDC6I_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NICA_HUMAN | [view interactions] | Low throughput | no | yes |
RB22A_HUMAN | [view interactions] | Low throughput | no | yes |
STX6_HUMAN | [view interactions] | Low throughput | no | yes |
RAB5B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RAB5A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SAMD9_HUMAN | [view interactions] | Low throughput | no | yes |
SAM9L_HUMAN | [view interactions] | Low throughput | no | yes |
CDC73_HUMAN | [view interactions] | Low throughput | no | yes |
RAB31_HUMAN | [view interactions] | Low throughput | no | yes |
RAB5C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CFTR_HUMAN | [view interactions] | Low throughput | no | no |
RAB14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MPRI_HUMAN | [view interactions] | Low throughput | no | yes |
ERBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
KI16B_HUMAN | [view interactions] | Low throughput | no | yes |
EGF_HUMAN | [view interactions] | Low throughput | no | no |
TM1L1_HUMAN | [view interactions] | Low throughput | no | yes |
ALS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RSPO3_HUMAN | [view interactions] | Low throughput | no | yes |
LRP2_HUMAN | [view interactions] | Low throughput | no | no |
EGFR_HUMAN | [view interactions] | Low throughput | no | no |
VAC14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RN167_HUMAN | [view interactions] | Low throughput | no | yes |
OLR1_HUMAN | [view interactions] | Low throughput | no | no |
TCPA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CAN7_HUMAN | [view interactions] | Low throughput | no | no |
EEA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
OPSD_HUMAN | [view interactions] | Low throughput | no | no |
ZFYV9_HUMAN | [view interactions] | Low throughput | no | yes |
RABX5_HUMAN | [view interactions] | Low throughput | no | no |
GRAB_HUMAN | [view interactions] | Low throughput | no | no |
TGFA1_HUMAN | [view interactions] | Low throughput | no | no |
ZFY16_HUMAN | [view interactions] | Low throughput | no | yes |
VIP2_HUMAN | [view interactions] | High throughput | no | yes |
ECM29_HUMAN | [view interactions] | High throughput | no | no |
RUFY2_HUMAN | [view interactions] | High throughput | no | yes |
KIF5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
GLO2_HUMAN | [view interactions] | High throughput | no | yes |
RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
S6A15_HUMAN | [view interactions] | High throughput | no | yes |
PTN23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRPE1_HUMAN | [view interactions] | High throughput | no | yes |
VPS45_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
F135A_HUMAN | [view interactions] | High throughput | no | yes |
DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PDLI1_HUMAN | [view interactions] | High throughput | no | yes |
DVL2_HUMAN | [view interactions] | High throughput | no | yes |
IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
LSM8_HUMAN | [view interactions] | High throughput | no | yes |
LRBA_HUMAN | [view interactions] | High throughput | no | yes |
RS29_HUMAN | [view interactions] | High throughput | no | yes |
KEAP1_HUMAN | [view interactions] | High throughput | no | yes |
GAPD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCM1_HUMAN | [view interactions] | High throughput | no | yes |
RRP12_HUMAN | [view interactions] | High throughput | no | no |
TPGS1_HUMAN | [view interactions] | High throughput | no | no |
HAUS6_HUMAN | [view interactions] | High throughput | no | yes |
LRC49_HUMAN | [view interactions] | High throughput | no | no |
DVL3_HUMAN | [view interactions] | High throughput | no | yes |
GTPB4_HUMAN | [view interactions] | High throughput | no | yes |
CSTP1_HUMAN | [view interactions] | High throughput | no | yes |
DBLOH_HUMAN | [view interactions] | High throughput | no | no |
PDGFC_HUMAN | [view interactions] | High throughput | no | no |
MRTFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
PIBF1_HUMAN | [view interactions] | High throughput | no | yes |
PTPRQ_HUMAN | [view interactions] | High throughput | no | no |
CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
RING2_HUMAN | [view interactions] | High throughput | no | yes |
FCG2A_HUMAN | [view interactions] | High throughput | no | no |
PPR3C_HUMAN | [view interactions] | High throughput | no | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RBCC1_HUMAN | [view interactions] | High throughput | no | no |
IL24_HUMAN | [view interactions] | High throughput | no | no |
CAMP2_HUMAN | [view interactions] | High throughput | no | yes |
E41L5_HUMAN | [view interactions] | High throughput | no | no |
BCORL_HUMAN | [view interactions] | High throughput | no | no |
NUP58_HUMAN | [view interactions] | High throughput | no | yes |
WDR76_HUMAN | [view interactions] | High throughput | no | no |
H4_HUMAN | [view interactions] | High throughput | no | yes |
H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BIRC3_HUMAN | [view interactions] | High throughput | no | no |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
KIF14_HUMAN | [view interactions] | High throughput | no | no |
ZNRF2_HUMAN | [view interactions] | High throughput | no | yes |
CEA16_HUMAN | [view interactions] | High throughput | no | no |
KRT38_HUMAN | [view interactions] | High throughput | no | no |
HSBP1_HUMAN | [view interactions] | High throughput | no | no |
BRK1_HUMAN | [view interactions] | High throughput | no | no |
KRT37_HUMAN | [view interactions] | High throughput | no | no |
BET1_HUMAN | [view interactions] | High throughput | no | no |
MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SYCE1_HUMAN | [view interactions] | High throughput | no | no |
FBSP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EP300_HUMAN | [view interactions] | High throughput | no | yes |
FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
FBX43_HUMAN | [view interactions] | High throughput | no | no |
CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RANG_HUMAN | [view interactions] | High throughput | no | no |
SMCA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H2B1C_HUMAN | [view interactions] | High throughput | no | yes |
PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AIF1L_HUMAN | [view interactions] | High throughput | no | yes |
H2A2A_HUMAN | [view interactions] | High throughput | no | yes |
GBA1_HUMAN | [view interactions] | High throughput | no | yes |
CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
BAP1_HUMAN | [view interactions] | High throughput | no | yes |
LOXL2_HUMAN | [view interactions] | High throughput | no | yes |
RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MOB3C_HUMAN | [view interactions] | High throughput | no | no |
UBP7_HUMAN | [view interactions] | High throughput | no | yes |
ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
SORT_HUMAN | [view interactions] | High throughput | no | yes |
SYMC_HUMAN | [view interactions] | High throughput | no | yes |
OCRL_HUMAN | [view interactions] | High throughput | no | yes |
USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCEA1_HUMAN | [view interactions] | High throughput | no | no |
VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCH2_HUMAN | [view interactions] | High throughput | no | no |
GRHL2_HUMAN | [view interactions] | High throughput | no | yes |
SETD3_HUMAN | [view interactions] | High throughput | no | yes |
TM237_HUMAN | [view interactions] | High throughput | no | no |
VPS18_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AGR2_HUMAN | [view interactions] | High throughput | no | no |
ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
LAMP3_HUMAN | [view interactions] | High throughput | no | no |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IFM1_HUMAN | [view interactions] | High throughput | no | no |
IFM3_HUMAN | [view interactions] | High throughput | no | yes |
ACE2_HUMAN | [view interactions] | High throughput | no | no |
TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IRAK1_HUMAN | [view interactions] | High throughput | no | yes |
DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RGAP1_HUMAN | [view interactions] | High throughput | no | no |
TNKS2_HUMAN | [view interactions] | High throughput | no | no |
NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
OSBL1_HUMAN | [view interactions] | High throughput | no | yes |
IRGQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OAS3_HUMAN | [view interactions] | High throughput | no | no |
FN3K_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BEGIN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
APC4_HUMAN | [view interactions] | High throughput | no | yes |
CNDG2_HUMAN | [view interactions] | High throughput | no | yes |
NEUL_HUMAN | [view interactions] | High throughput | no | yes |
ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WWP2_HUMAN | [view interactions] | High throughput | no | no |
ASF1B_HUMAN | [view interactions] | High throughput | no | yes |
TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MARK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCNA_HUMAN | [view interactions] | High throughput | no | no |
TRIPB_HUMAN | [view interactions] | High throughput | no | yes |
SNR27_HUMAN | [view interactions] | High throughput | no | yes |
AF17_HUMAN | [view interactions] | High throughput | no | yes |
PAI2_HUMAN | [view interactions] | High throughput | no | no |
UBP47_HUMAN | [view interactions] | High throughput | no | yes |
BMP1_HUMAN | [view interactions] | High throughput | no | yes |
TMA16_HUMAN | [view interactions] | High throughput | no | yes |
FUCM_HUMAN | [view interactions] | High throughput | no | yes |
FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RT12_HUMAN | [view interactions] | High throughput | no | yes |
SC16A_HUMAN | [view interactions] | High throughput | no | yes |
PIMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SEC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAZ_HUMAN | [view interactions] | High throughput | no | yes |
RBM33_HUMAN | [view interactions] | High throughput | no | yes |
RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BMI1_HUMAN | [view interactions] | High throughput | no | yes |
LRP6_HUMAN | [view interactions] | High throughput | no | yes |
FZD5_HUMAN | [view interactions] | High throughput | no | yes |
AXIN1_HUMAN | [view interactions] | High throughput | no | yes |
NISCH_HUMAN | [view interactions] | High throughput | no | yes |