Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

EEA1_HUMAN

Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in EEA1_HUMAN
GO:0000166 nucleotide binding 33.8710 4 no
GO:0017076 purine nucleotide binding 33.8710 5 no
GO:0032555 purine ribonucleotide binding 32.2581 4 no
GO:0035639 purine ribonucleoside triphosphate binding 32.2581 4 no
GO:0043168 anion binding 32.2581 4 no
GO:0043169 cation binding 25.8065 4 yes
GO:0046872 metal ion binding 24.1935 5 yes
GO:0030554 adenyl nucleotide binding 22.5806 6 no
GO:0005524 ATP binding 20.9677 5 no
GO:0032559 adenyl ribonucleotide binding 20.9677 5 no
GO:0042803 protein homodimerization activity 14.5161 4 yes
GO:0046914 transition metal ion binding 12.9032 6 yes
GO:0008270 zinc ion binding 11.2903 7 yes
GO:0035091 phosphatidylinositol binding 8.0645 4 yes
GO:0005545 1-phosphatidylinositol binding 3.2258 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in EEA1_HUMAN
GO:0008104 protein localization 51.6129 4 no
GO:0006996 organelle organization 48.3871 4 yes
GO:0048522 positive regulation of cellular process 48.3871 4 no
GO:0051128 regulation of cellular component organization 45.1613 4 no
GO:0060255 regulation of macromolecule metabolic process 43.5484 4 no
GO:0071702 organic substance transport 40.3226 4 no
GO:0071705 nitrogen compound transport 40.3226 4 no
GO:0031323 regulation of cellular metabolic process 38.7097 4 no
GO:0009893 positive regulation of metabolic process 38.7097 4 no
GO:0010604 positive regulation of macromolecule metabolic process 38.7097 5 no
GO:0080090 regulation of primary metabolic process 38.7097 4 no
GO:0015031 protein transport 38.7097 4 no
GO:0010646 regulation of cell communication 33.8710 4 no
GO:0051049 regulation of transport 32.2581 4 no
GO:0009889 regulation of biosynthetic process 32.2581 4 no
GO:0006886 intracellular protein transport 32.2581 4 no
GO:0031325 positive regulation of cellular metabolic process 30.6452 5 no
GO:0031326 regulation of cellular biosynthetic process 30.6452 5 no
GO:0048523 negative regulation of cellular process 30.6452 4 no
GO:0009966 regulation of signal transduction 29.0323 4 no
GO:0010556 regulation of macromolecule biosynthetic process 29.0323 5 no
GO:0022607 cellular component assembly 29.0323 4 no
GO:0023056 positive regulation of signaling 29.0323 4 no
GO:0051246 regulation of protein metabolic process 29.0323 5 no
GO:0010468 regulation of gene expression 27.4194 6 no
GO:0010647 positive regulation of cell communication 27.4194 5 no
GO:0036211 protein modification process 27.4194 4 no
GO:0043412 macromolecule modification 27.4194 4 no
GO:0048584 positive regulation of response to stimulus 27.4194 4 no
GO:0051247 positive regulation of protein metabolic process 27.4194 6 no
GO:0009891 positive regulation of biosynthetic process 25.8065 5 no
GO:0009967 positive regulation of signal transduction 25.8065 5 no
GO:0032880 regulation of protein localization 25.8065 5 no
GO:0060341 regulation of cellular localization 25.8065 4 no
GO:0016050 vesicle organization 24.1935 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 24.1935 6 no
GO:0060627 regulation of vesicle-mediated transport 22.5806 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 22.5806 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 22.5806 5 no
GO:0031399 regulation of protein modification process 22.5806 6 no
GO:0051130 positive regulation of cellular component organization 22.5806 5 no
GO:0098657 import into cell 20.9677 4 yes
GO:0006796 phosphate-containing compound metabolic process 20.9677 4 no
GO:0031401 positive regulation of protein modification process 20.9677 7 no
GO:0033043 regulation of organelle organization 20.9677 5 no
GO:0043933 protein-containing complex organization 20.9677 4 no
GO:0048585 negative regulation of response to stimulus 20.9677 4 no
GO:1902531 regulation of intracellular signal transduction 20.9677 5 no
GO:0061024 membrane organization 19.3548 4 yes
GO:0061025 membrane fusion 14.5161 5 yes
GO:0007032 endosome organization 12.9032 6 yes
GO:0006906 vesicle fusion 11.2903 6 yes
GO:0048284 organelle fusion 11.2903 5 yes
GO:0090174 organelle membrane fusion 11.2903 6 yes
GO:0044788 modulation by host of viral process 6.4516 5 yes
GO:0045022 early endosome to late endosome transport 6.4516 5 yes
GO:0051851 modulation by host of symbiont process 6.4516 4 yes
GO:0098927 vesicle-mediated transport between endosomal compartments 6.4516 4 yes
GO:0016189 synaptic vesicle to endosome fusion 3.2258 6 yes
GO:0099565 chemical synaptic transmission, postsynaptic 3.2258 4 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TOM1_HUMAN [view interactions] Low throughput no yes
CY24B_HUMAN [view interactions] Low throughput no no
ITB2_HUMAN [view interactions] Low throughput no no
RASF5_HUMAN [view interactions] Low throughput no yes
STK4_HUMAN [view interactions] Low throughput no yes
VGFR2_HUMAN [view interactions] Low throughput no no
VGFR1_HUMAN [view interactions] Low throughput no no
SNX27_HUMAN [view entry] [view interactions] Low throughput yes no
IGF1R_HUMAN [view entry] [view interactions] Low throughput yes yes
RABE1_HUMAN [view entry] [view interactions] Low throughput yes yes
TERA_HUMAN [view entry] [view interactions] Low throughput yes yes
P53_HUMAN [view interactions] Low throughput no no
STX12_HUMAN [view entry] [view interactions] Low throughput yes yes
RAD_HUMAN [view interactions] Low throughput no yes
PXK_HUMAN [view interactions] Low throughput no yes
ACK1_HUMAN [view entry] [view interactions] Low throughput yes yes
WASH1_HUMAN [view interactions] Low throughput no yes
VPS35_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP8_HUMAN [view entry] [view interactions] Low throughput yes no
1433S_HUMAN [view entry] [view interactions] Low throughput yes yes
PROM1_HUMAN [view interactions] Low throughput no no
MBP_HUMAN [view entry] [view interactions] Low throughput yes no
MYPR_HUMAN [view entry] [view interactions] Low throughput yes yes
ADRB2_HUMAN [view entry] [view interactions] Low throughput yes no
NSF_HUMAN [view entry] [view interactions] Low throughput yes yes
PDC6I_HUMAN [view entry] [view interactions] Low throughput yes yes
NICA_HUMAN [view interactions] Low throughput no yes
RB22A_HUMAN [view interactions] Low throughput no yes
STX6_HUMAN [view interactions] Low throughput no yes
RAB5B_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB5A_HUMAN [view entry] [view interactions] Low throughput yes yes
SAMD9_HUMAN [view interactions] Low throughput no yes
SAM9L_HUMAN [view interactions] Low throughput no yes
CDC73_HUMAN [view interactions] Low throughput no yes
RAB31_HUMAN [view interactions] Low throughput no yes
RAB5C_HUMAN [view entry] [view interactions] Low throughput yes yes
CFTR_HUMAN [view interactions] Low throughput no no
RAB14_HUMAN [view entry] [view interactions] Low throughput yes yes
MPRI_HUMAN [view interactions] Low throughput no yes
ERBB2_HUMAN [view entry] [view interactions] Low throughput yes no
KI16B_HUMAN [view interactions] Low throughput no yes
EGF_HUMAN [view interactions] Low throughput no no
TM1L1_HUMAN [view interactions] Low throughput no yes
ALS2_HUMAN [view entry] [view interactions] Low throughput yes yes
RSPO3_HUMAN [view interactions] Low throughput no yes
LRP2_HUMAN [view interactions] Low throughput no no
EGFR_HUMAN [view interactions] Low throughput no no
VAC14_HUMAN [view entry] [view interactions] Low throughput yes yes
RN167_HUMAN [view interactions] Low throughput no yes
OLR1_HUMAN [view interactions] Low throughput no no
TCPA_HUMAN [view entry] [view interactions] Low throughput yes yes
CAN7_HUMAN [view interactions] Low throughput no no
EEA1_HUMAN [view entry] [view interactions] Low throughput yes yes
OPSD_HUMAN [view interactions] Low throughput no no
ZFYV9_HUMAN [view interactions] Low throughput no yes
RABX5_HUMAN [view interactions] Low throughput no no
GRAB_HUMAN [view interactions] Low throughput no no
TGFA1_HUMAN [view interactions] Low throughput no no
ZFY16_HUMAN [view interactions] Low throughput no yes
VIP2_HUMAN [view interactions] High throughput no yes
ECM29_HUMAN [view interactions] High throughput no no
RUFY2_HUMAN [view interactions] High throughput no yes
KIF5C_HUMAN [view entry] [view interactions] High throughput yes yes
ABCE1_HUMAN [view interactions] High throughput no yes
GLO2_HUMAN [view interactions] High throughput no yes
RUFY1_HUMAN [view interactions] High throughput no yes
S6A15_HUMAN [view interactions] High throughput no yes
PTN23_HUMAN [view entry] [view interactions] High throughput yes yes
GRPE1_HUMAN [view interactions] High throughput no yes
VPS45_HUMAN [view entry] [view interactions] High throughput yes yes
F135A_HUMAN [view interactions] High throughput no yes
DP13A_HUMAN [view entry] [view interactions] High throughput yes yes
PDLI1_HUMAN [view interactions] High throughput no yes
DVL2_HUMAN [view interactions] High throughput no yes
IF4G3_HUMAN [view interactions] High throughput no yes
LSM8_HUMAN [view interactions] High throughput no yes
LRBA_HUMAN [view interactions] High throughput no yes
RS29_HUMAN [view interactions] High throughput no yes
KEAP1_HUMAN [view interactions] High throughput no yes
GAPD1_HUMAN [view entry] [view interactions] High throughput yes yes
PCM1_HUMAN [view interactions] High throughput no yes
RRP12_HUMAN [view interactions] High throughput no no
TPGS1_HUMAN [view interactions] High throughput no no
HAUS6_HUMAN [view interactions] High throughput no yes
LRC49_HUMAN [view interactions] High throughput no no
DVL3_HUMAN [view interactions] High throughput no yes
GTPB4_HUMAN [view interactions] High throughput no yes
CSTP1_HUMAN [view interactions] High throughput no yes
DBLOH_HUMAN [view interactions] High throughput no no
PDGFC_HUMAN [view interactions] High throughput no no
MRTFB_HUMAN [view entry] [view interactions] High throughput yes yes
FHI2B_HUMAN [view interactions] High throughput no yes
PIBF1_HUMAN [view interactions] High throughput no yes
PTPRQ_HUMAN [view interactions] High throughput no no
CCDC8_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
FCG2A_HUMAN [view interactions] High throughput no no
PPR3C_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RBCC1_HUMAN [view interactions] High throughput no no
IL24_HUMAN [view interactions] High throughput no no
CAMP2_HUMAN [view interactions] High throughput no yes
E41L5_HUMAN [view interactions] High throughput no no
BCORL_HUMAN [view interactions] High throughput no no
NUP58_HUMAN [view interactions] High throughput no yes
WDR76_HUMAN [view interactions] High throughput no no
H4_HUMAN [view interactions] High throughput no yes
H2A1B_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
ZNRF2_HUMAN [view interactions] High throughput no yes
CEA16_HUMAN [view interactions] High throughput no no
KRT38_HUMAN [view interactions] High throughput no no
HSBP1_HUMAN [view interactions] High throughput no no
BRK1_HUMAN [view interactions] High throughput no no
KRT37_HUMAN [view interactions] High throughput no no
BET1_HUMAN [view interactions] High throughput no no
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
SYCE1_HUMAN [view interactions] High throughput no no
FBSP1_HUMAN [view entry] [view interactions] High throughput yes no
CLCA_HUMAN [view entry] [view interactions] High throughput yes no
EP300_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
FBX43_HUMAN [view interactions] High throughput no no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
PARP1_HUMAN [view entry] [view interactions] High throughput yes yes
RANG_HUMAN [view interactions] High throughput no no
SMCA1_HUMAN [view entry] [view interactions] High throughput yes yes
H2B1C_HUMAN [view interactions] High throughput no yes
PDLI7_HUMAN [view entry] [view interactions] High throughput yes no
AIF1L_HUMAN [view interactions] High throughput no yes
H2A2A_HUMAN [view interactions] High throughput no yes
GBA1_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
LOXL2_HUMAN [view interactions] High throughput no yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
MOB3C_HUMAN [view interactions] High throughput no no
UBP7_HUMAN [view interactions] High throughput no yes
ATG9A_HUMAN [view interactions] High throughput no yes
SORT_HUMAN [view interactions] High throughput no yes
SYMC_HUMAN [view interactions] High throughput no yes
OCRL_HUMAN [view interactions] High throughput no yes
USO1_HUMAN [view entry] [view interactions] High throughput yes yes
TCEA1_HUMAN [view interactions] High throughput no no
VATA_HUMAN [view entry] [view interactions] High throughput yes yes
PCH2_HUMAN [view interactions] High throughput no no
GRHL2_HUMAN [view interactions] High throughput no yes
SETD3_HUMAN [view interactions] High throughput no yes
TM237_HUMAN [view interactions] High throughput no no
VPS18_HUMAN [view entry] [view interactions] High throughput yes no
AGR2_HUMAN [view interactions] High throughput no no
ANFY1_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP2_HUMAN [view interactions] High throughput no yes
LAMP3_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB4A_HUMAN [view entry] [view interactions] High throughput yes no
RAB9A_HUMAN [view interactions] High throughput no yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
IFM1_HUMAN [view interactions] High throughput no no
IFM3_HUMAN [view interactions] High throughput no yes
ACE2_HUMAN [view interactions] High throughput no no
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
IRAK1_HUMAN [view interactions] High throughput no yes
DCTN2_HUMAN [view entry] [view interactions] High throughput yes yes
RGAP1_HUMAN [view interactions] High throughput no no
TNKS2_HUMAN [view interactions] High throughput no no
NPHP4_HUMAN [view interactions] High throughput no yes
PSPC1_HUMAN [view interactions] High throughput no yes
OSBL1_HUMAN [view interactions] High throughput no yes
IRGQ_HUMAN [view entry] [view interactions] High throughput yes yes
OAS3_HUMAN [view interactions] High throughput no no
FN3K_HUMAN [view entry] [view interactions] High throughput yes no
BEGIN_HUMAN [view entry] [view interactions] High throughput yes no
APC4_HUMAN [view interactions] High throughput no yes
CNDG2_HUMAN [view interactions] High throughput no yes
NEUL_HUMAN [view interactions] High throughput no yes
ABL1_HUMAN [view entry] [view interactions] High throughput yes yes
WWP2_HUMAN [view interactions] High throughput no no
ASF1B_HUMAN [view interactions] High throughput no yes
TPIS_HUMAN [view entry] [view interactions] High throughput yes yes
MARK2_HUMAN [view entry] [view interactions] High throughput yes yes
PCNA_HUMAN [view interactions] High throughput no no
TRIPB_HUMAN [view interactions] High throughput no yes
SNR27_HUMAN [view interactions] High throughput no yes
AF17_HUMAN [view interactions] High throughput no yes
PAI2_HUMAN [view interactions] High throughput no no
UBP47_HUMAN [view interactions] High throughput no yes
BMP1_HUMAN [view interactions] High throughput no yes
TMA16_HUMAN [view interactions] High throughput no yes
FUCM_HUMAN [view interactions] High throughput no yes
FGFR3_HUMAN [view interactions] High throughput no yes
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
RT12_HUMAN [view interactions] High throughput no yes
SC16A_HUMAN [view interactions] High throughput no yes
PIMT_HUMAN [view entry] [view interactions] High throughput yes yes
SEC13_HUMAN [view entry] [view interactions] High throughput yes yes
MAZ_HUMAN [view interactions] High throughput no yes
RBM33_HUMAN [view interactions] High throughput no yes
RUVB1_HUMAN [view interactions] High throughput no yes
IMB1_HUMAN [view entry] [view interactions] High throughput yes yes
BMI1_HUMAN [view interactions] High throughput no yes
LRP6_HUMAN [view interactions] High throughput no yes
FZD5_HUMAN [view interactions] High throughput no yes
AXIN1_HUMAN [view interactions] High throughput no yes
NISCH_HUMAN [view interactions] High throughput no yes