Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

IRGQ_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in IRGQ_HUMAN
GO:0008017 microtubule binding 50.0000 5 no
GO:0015631 tubulin binding 50.0000 4 no
GO:0031625 ubiquitin protein ligase binding 25.0000 5 no
GO:0044389 ubiquitin-like protein ligase binding 25.0000 4 no
GO:0046872 metal ion binding 25.0000 4 no
GO:0046914 transition metal ion binding 25.0000 5 no
GO:0001664 G protein-coupled receptor binding 25.0000 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in IRGQ_HUMAN
GO:0006996 organelle organization 62.5000 4 no
GO:0022607 cellular component assembly 62.5000 4 no
GO:0030030 cell projection organization 50.0000 4 no
GO:0051049 regulation of transport 50.0000 4 no
GO:0060341 regulation of cellular localization 50.0000 4 no
GO:0016192 vesicle-mediated transport 50.0000 4 no
GO:0010646 regulation of cell communication 50.0000 4 no
GO:0031344 regulation of cell projection organization 37.5000 5 no
GO:0032386 regulation of intracellular transport 37.5000 5 no
GO:0048522 positive regulation of cellular process 37.5000 4 no
GO:0048523 negative regulation of cellular process 37.5000 4 no
GO:0051128 regulation of cellular component organization 37.5000 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 37.5000 6 no
GO:0120036 plasma membrane bounded cell projection organization 37.5000 5 no
GO:0010038 response to metal ion 37.5000 4 no
GO:0010243 response to organonitrogen compound 37.5000 4 no
GO:0031667 response to nutrient levels 37.5000 4 no
GO:0043933 protein-containing complex organization 37.5000 4 no
GO:1901701 cellular response to oxygen-containing compound 37.5000 4 no
GO:0009892 negative regulation of metabolic process 37.5000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 37.5000 5 no
GO:0051171 regulation of nitrogen compound metabolic process 37.5000 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 37.5000 5 no
GO:0051246 regulation of protein metabolic process 37.5000 5 no
GO:0060255 regulation of macromolecule metabolic process 37.5000 4 no
GO:0080090 regulation of primary metabolic process 37.5000 4 no
GO:0009966 regulation of signal transduction 37.5000 4 no
GO:0010959 regulation of metal ion transport 25.0000 6 no
GO:0010975 regulation of neuron projection development 25.0000 7 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.0000 5 no
GO:0022603 regulation of anatomical structure morphogenesis 25.0000 4 no
GO:0022898 regulation of transmembrane transporter activity 25.0000 4 no
GO:0023057 negative regulation of signaling 25.0000 4 no
GO:0031175 neuron projection development 25.0000 6 no
GO:0031323 regulation of cellular metabolic process 25.0000 4 no
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 no
GO:0031326 regulation of cellular biosynthetic process 25.0000 5 no
GO:0032388 positive regulation of intracellular transport 25.0000 5 no
GO:0032412 regulation of ion transmembrane transporter activity 25.0000 5 no
GO:0034330 cell junction organization 25.0000 4 no
GO:0034762 regulation of transmembrane transport 25.0000 4 no
GO:0034765 regulation of ion transmembrane transport 25.0000 5 no
GO:0043266 regulation of potassium ion transport 25.0000 7 no
GO:0043269 regulation of ion transport 25.0000 5 no
GO:0048585 negative regulation of response to stimulus 25.0000 4 no
GO:0050807 regulation of synapse organization 25.0000 5 no
GO:0050808 synapse organization 25.0000 5 no
GO:0051050 positive regulation of transport 25.0000 4 no
GO:0051051 negative regulation of transport 25.0000 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 25.0000 5 no
GO:0051247 positive regulation of protein metabolic process 25.0000 6 no
GO:0051252 regulation of RNA metabolic process 25.0000 5 no
GO:1901379 regulation of potassium ion transmembrane transport 25.0000 7 no
GO:1902531 regulation of intracellular signal transduction 25.0000 5 no
GO:1903506 regulation of nucleic acid-templated transcription 25.0000 7 no
GO:1904062 regulation of cation transmembrane transport 25.0000 6 no
GO:2001141 regulation of RNA biosynthetic process 25.0000 6 no
GO:0007010 cytoskeleton organization 25.0000 5 no
GO:0007409 axonogenesis 25.0000 8 no
GO:0032990 cell part morphogenesis 25.0000 4 no
GO:0048812 neuron projection morphogenesis 25.0000 7 no
GO:0048858 cell projection morphogenesis 25.0000 5 no
GO:0050804 modulation of chemical synaptic transmission 25.0000 5 no
GO:0051129 negative regulation of cellular component organization 25.0000 5 no
GO:0071310 cellular response to organic substance 25.0000 4 no
GO:0071417 cellular response to organonitrogen compound 25.0000 4 no
GO:0099177 regulation of trans-synaptic signaling 25.0000 4 no
GO:0120039 plasma membrane bounded cell projection morphogenesis 25.0000 6 no
GO:1901652 response to peptide 25.0000 4 no
GO:1901653 cellular response to peptide 25.0000 5 no
GO:1901699 cellular response to nitrogen compound 25.0000 4 no
GO:0032880 regulation of protein localization 25.0000 5 no
GO:0051223 regulation of protein transport 25.0000 5 no
GO:0065003 protein-containing complex assembly 25.0000 5 no
GO:0070201 regulation of establishment of protein localization 25.0000 6 no
GO:0000045 autophagosome assembly 25.0000 6 no
GO:0000422 autophagy of mitochondrion 25.0000 4 no
GO:0006995 cellular response to nitrogen starvation 25.0000 5 no
GO:0007005 mitochondrion organization 25.0000 5 no
GO:0007033 vacuole organization 25.0000 5 no
GO:0009267 cellular response to starvation 25.0000 4 no
GO:0014070 response to organic cyclic compound 25.0000 4 no
GO:0016236 macroautophagy 25.0000 4 no
GO:0022411 cellular component disassembly 25.0000 4 no
GO:0031669 cellular response to nutrient levels 25.0000 4 no
GO:0043562 cellular response to nitrogen levels 25.0000 5 no
GO:0046688 response to copper ion 25.0000 5 no
GO:0061726 mitochondrion disassembly 25.0000 6 no
GO:0070925 organelle assembly 25.0000 5 no
GO:0071241 cellular response to inorganic substance 25.0000 4 no
GO:0071248 cellular response to metal ion 25.0000 5 no
GO:0071280 cellular response to copper ion 25.0000 6 no
GO:1903008 organelle disassembly 25.0000 5 no
GO:1905037 autophagosome organization 25.0000 6 no
GO:0008104 protein localization 25.0000 4 no
GO:0009894 regulation of catabolic process 25.0000 4 no
GO:0015031 protein transport 25.0000 4 no
GO:0030162 regulation of proteolysis 25.0000 6 no
GO:0033365 protein localization to organelle 25.0000 5 no
GO:0042176 regulation of protein catabolic process 25.0000 5 no
GO:0045861 negative regulation of proteolysis 25.0000 7 no
GO:0048193 Golgi vesicle transport 25.0000 5 no
GO:0051248 negative regulation of protein metabolic process 25.0000 6 no
GO:0071702 organic substance transport 25.0000 4 no
GO:0071705 nitrogen compound transport 25.0000 4 no
GO:0006897 endocytosis 25.0000 5 no
GO:0006355 regulation of DNA-templated transcription 25.0000 6 no
GO:0009889 regulation of biosynthetic process 25.0000 4 no
GO:0009893 positive regulation of metabolic process 25.0000 4 no
GO:0009968 negative regulation of signal transduction 25.0000 5 no
GO:0010468 regulation of gene expression 25.0000 5 no
GO:0010556 regulation of macromolecule biosynthetic process 25.0000 5 no
GO:0010604 positive regulation of macromolecule metabolic process 25.0000 5 no
GO:0010648 negative regulation of cell communication 25.0000 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
CDK1_HUMAN [view interactions] High throughput no no
EEA1_HUMAN [view entry] [view interactions] High throughput yes yes
SETD3_HUMAN [view interactions] High throughput no yes
ZSC26_HUMAN [view interactions] High throughput no no
TMEDA_HUMAN [view interactions] High throughput no yes
PLK2_HUMAN [view interactions] High throughput no yes
OR5F1_HUMAN [view interactions] High throughput no no
TF2LY_HUMAN [view interactions] High throughput no no
MFTC_HUMAN [view interactions] High throughput no yes
NPC2_HUMAN [view interactions] High throughput no yes
SCG3_HUMAN [view interactions] High throughput no yes
O10H3_HUMAN [view interactions] High throughput no no
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
NFYA_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
BACD3_HUMAN [view interactions] High throughput no yes
BCAR1_HUMAN [view interactions] High throughput no yes
XPP1_HUMAN [view interactions] High throughput no yes
ATG4B_HUMAN [view interactions] High throughput no yes
L2GL1_HUMAN [view entry] [view interactions] High throughput yes yes
MAP1B_HUMAN [view entry] [view interactions] High throughput yes yes
TSR2_HUMAN [view interactions] High throughput no yes
UB2R2_HUMAN [view interactions] High throughput no no
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes