Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

IRGQ_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in IRGQ_HUMAN
GO:0015631 tubulin binding 45.4545 4 no
GO:0008017 microtubule binding 36.3636 5 no
GO:0000166 nucleotide binding 27.2727 4 yes
GO:0017076 purine nucleotide binding 27.2727 5 yes
GO:0032555 purine ribonucleotide binding 27.2727 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 27.2727 4 yes
GO:0043168 anion binding 27.2727 4 yes
GO:0001664 G protein-coupled receptor binding 27.2727 4 no
GO:0043169 cation binding 27.2727 4 no
GO:0046872 metal ion binding 27.2727 5 no
GO:0046914 transition metal ion binding 27.2727 6 no
GO:0031625 ubiquitin protein ligase binding 27.2727 5 no
GO:0044389 ubiquitin-like protein ligase binding 27.2727 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in IRGQ_HUMAN
GO:0006996 organelle organization 63.6364 4 no
GO:0010646 regulation of cell communication 54.5455 4 no
GO:0022607 cellular component assembly 54.5455 4 no
GO:0009892 negative regulation of metabolic process 45.4545 4 no
GO:0009966 regulation of signal transduction 45.4545 4 no
GO:0031323 regulation of cellular metabolic process 45.4545 4 no
GO:0048522 positive regulation of cellular process 45.4545 4 no
GO:0048523 negative regulation of cellular process 45.4545 4 no
GO:0051049 regulation of transport 45.4545 4 no
GO:0051128 regulation of cellular component organization 45.4545 4 no
GO:0051246 regulation of protein metabolic process 45.4545 5 no
GO:0060255 regulation of macromolecule metabolic process 45.4545 4 no
GO:0060341 regulation of cellular localization 45.4545 4 no
GO:0080090 regulation of primary metabolic process 45.4545 4 no
GO:0009894 regulation of catabolic process 45.4545 4 no
GO:0009893 positive regulation of metabolic process 36.3636 4 no
GO:0010038 response to metal ion 36.3636 4 no
GO:0010604 positive regulation of macromolecule metabolic process 36.3636 5 no
GO:0010605 negative regulation of macromolecule metabolic process 36.3636 5 no
GO:0010648 negative regulation of cell communication 36.3636 5 no
GO:0023057 negative regulation of signaling 36.3636 4 no
GO:0030030 cell projection organization 36.3636 4 no
GO:0031324 negative regulation of cellular metabolic process 36.3636 5 no
GO:0043933 protein-containing complex organization 36.3636 4 no
GO:0048585 negative regulation of response to stimulus 36.3636 4 no
GO:0050804 modulation of chemical synaptic transmission 36.3636 5 no
GO:0051247 positive regulation of protein metabolic process 36.3636 6 no
GO:0099177 regulation of trans-synaptic signaling 36.3636 4 no
GO:1901701 cellular response to oxygen-containing compound 36.3636 4 no
GO:1902531 regulation of intracellular signal transduction 36.3636 5 no
GO:0010506 regulation of autophagy 36.3636 6 no
GO:0022603 regulation of anatomical structure morphogenesis 36.3636 4 no
GO:0031329 regulation of cellular catabolic process 36.3636 5 no
GO:0042176 regulation of protein catabolic process 36.3636 5 no
GO:0006355 regulation of DNA-templated transcription 27.2727 7 no
GO:0009889 regulation of biosynthetic process 27.2727 4 no
GO:0009890 negative regulation of biosynthetic process 27.2727 5 no
GO:0009968 negative regulation of signal transduction 27.2727 5 no
GO:0010243 response to organonitrogen compound 27.2727 4 no
GO:0010468 regulation of gene expression 27.2727 6 no
GO:0010556 regulation of macromolecule biosynthetic process 27.2727 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 27.2727 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 27.2727 5 no
GO:0030162 regulation of proteolysis 27.2727 6 no
GO:0031325 positive regulation of cellular metabolic process 27.2727 5 no
GO:0031326 regulation of cellular biosynthetic process 27.2727 5 no
GO:0031327 negative regulation of cellular biosynthetic process 27.2727 6 no
GO:0031344 regulation of cell projection organization 27.2727 5 no
GO:0032880 regulation of protein localization 27.2727 5 no
GO:0042981 regulation of apoptotic process 27.2727 5 no
GO:0043066 negative regulation of apoptotic process 27.2727 6 no
GO:0043067 regulation of programmed cell death 27.2727 4 no
GO:0043069 negative regulation of programmed cell death 27.2727 5 no
GO:0050890 cognition 27.2727 4 no
GO:0051129 negative regulation of cellular component organization 27.2727 5 no
GO:0051248 negative regulation of protein metabolic process 27.2727 6 no
GO:0051252 regulation of RNA metabolic process 27.2727 5 no
GO:0065003 protein-containing complex assembly 27.2727 5 no
GO:0070201 regulation of establishment of protein localization 27.2727 6 no
GO:0071241 cellular response to inorganic substance 27.2727 4 no
GO:0071248 cellular response to metal ion 27.2727 5 no
GO:0071310 cellular response to organic substance 27.2727 4 no
GO:0071417 cellular response to organonitrogen compound 27.2727 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 27.2727 6 no
GO:0120036 plasma membrane bounded cell projection organization 27.2727 5 no
GO:1901699 cellular response to nitrogen compound 27.2727 4 no
GO:2001141 regulation of RNA biosynthetic process 27.2727 6 no
GO:0007010 cytoskeleton organization 27.2727 5 no
GO:0009896 positive regulation of catabolic process 27.2727 5 no
GO:0009967 positive regulation of signal transduction 27.2727 5 no
GO:0010647 positive regulation of cell communication 27.2727 5 no
GO:0023056 positive regulation of signaling 27.2727 4 no
GO:0033043 regulation of organelle organization 27.2727 5 no
GO:0036211 protein modification process 27.2727 4 no
GO:0043412 macromolecule modification 27.2727 4 no
GO:0044087 regulation of cellular component biogenesis 27.2727 4 no
GO:0045732 positive regulation of protein catabolic process 27.2727 6 no
GO:0048584 positive regulation of response to stimulus 27.2727 4 no
GO:1902533 positive regulation of intracellular signal transduction 27.2727 6 no
GO:0032386 regulation of intracellular transport 27.2727 5 no
GO:0051051 negative regulation of transport 27.2727 4 no
GO:0000422 autophagy of mitochondrion 27.2727 4 no
GO:0007005 mitochondrion organization 27.2727 5 no
GO:0008104 protein localization 27.2727 4 no
GO:0016236 macroautophagy 27.2727 4 no
GO:0022411 cellular component disassembly 27.2727 4 no
GO:0033365 protein localization to organelle 27.2727 5 no
GO:0071702 organic substance transport 27.2727 4 no
GO:0071705 nitrogen compound transport 27.2727 4 no
GO:0098657 import into cell 27.2727 4 no
GO:1903008 organelle disassembly 27.2727 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
CDK1_HUMAN [view interactions] High throughput no no
EEA1_HUMAN [view entry] [view interactions] High throughput yes yes
SETD3_HUMAN [view interactions] High throughput no yes
ZSC26_HUMAN [view interactions] High throughput no no
TMEDA_HUMAN [view interactions] High throughput no yes
PLK2_HUMAN [view entry] [view interactions] High throughput yes yes
OR5F1_HUMAN [view interactions] High throughput no no
TF2LY_HUMAN [view interactions] High throughput no no
S2532_HUMAN [view interactions] High throughput no yes
NPC2_HUMAN [view interactions] High throughput no yes
SCG3_HUMAN [view interactions] High throughput no yes
O10H3_HUMAN [view interactions] High throughput no no
PGFRB_HUMAN [view interactions] High throughput no yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
MD13L_HUMAN [view interactions] High throughput no no
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
NFYA_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
BACD3_HUMAN [view interactions] High throughput no yes
BCAR1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
XPP1_HUMAN [view interactions] High throughput no yes
ATG4B_HUMAN [view interactions] High throughput no yes
L2GL1_HUMAN [view entry] [view interactions] High throughput yes yes
MAP1B_HUMAN [view entry] [view interactions] High throughput yes yes
TSR2_HUMAN [view interactions] High throughput no yes
UB2R2_HUMAN [view interactions] High throughput no no
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
VATA_HUMAN [view entry] [view interactions] High throughput yes yes
SEPT2_HUMAN [view interactions] High throughput no no
BRD4_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes