Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ABLM3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ABLM3_HUMAN
GO:0046872 metal ion binding 53.8462 4 yes
GO:0019900 kinase binding 46.1538 4 no
GO:0019901 protein kinase binding 38.4615 5 no
GO:0003779 actin binding 30.7692 4 yes
GO:0016462 pyrophosphatase activity 30.7692 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 30.7692 4 no
GO:0017076 purine nucleotide binding 30.7692 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 30.7692 6 no
GO:0032555 purine ribonucleotide binding 30.7692 4 no
GO:0035639 purine ribonucleoside triphosphate binding 30.7692 4 no
GO:0003924 GTPase activity 23.0769 7 no
GO:0005525 GTP binding 23.0769 5 no
GO:0019001 guanyl nucleotide binding 23.0769 5 no
GO:0032561 guanyl ribonucleotide binding 23.0769 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in ABLM3_HUMAN
GO:0048522 positive regulation of cellular process 84.6154 4 yes
GO:0006996 organelle organization 69.2308 4 yes
GO:0007010 cytoskeleton organization 69.2308 5 yes
GO:0009893 positive regulation of metabolic process 61.5385 4 yes
GO:0022607 cellular component assembly 61.5385 4 yes
GO:0051128 regulation of cellular component organization 61.5385 4 no
GO:0010604 positive regulation of macromolecule metabolic process 53.8462 5 yes
GO:0030030 cell projection organization 53.8462 4 yes
GO:0031323 regulation of cellular metabolic process 53.8462 4 yes
GO:0060255 regulation of macromolecule metabolic process 53.8462 4 yes
GO:0120036 plasma membrane bounded cell projection organization 53.8462 5 yes
GO:0033043 regulation of organelle organization 53.8462 5 no
GO:0031325 positive regulation of cellular metabolic process 46.1538 5 yes
GO:0032880 regulation of protein localization 46.1538 5 yes
GO:0051049 regulation of transport 46.1538 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 46.1538 4 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 46.1538 5 yes
GO:0060341 regulation of cellular localization 46.1538 4 yes
GO:0080090 regulation of primary metabolic process 46.1538 4 yes
GO:0051493 regulation of cytoskeleton organization 46.1538 6 no
GO:0010468 regulation of gene expression 38.4615 5 yes
GO:0030031 cell projection assembly 38.4615 5 yes
GO:0051050 positive regulation of transport 38.4615 4 yes
GO:0051223 regulation of protein transport 38.4615 5 yes
GO:0070201 regulation of establishment of protein localization 38.4615 6 yes
GO:0031175 neuron projection development 38.4615 6 no
GO:0031344 regulation of cell projection organization 38.4615 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 38.4615 6 no
GO:0007264 small GTPase mediated signal transduction 38.4615 4 no
GO:0022603 regulation of anatomical structure morphogenesis 38.4615 4 no
GO:0032956 regulation of actin cytoskeleton organization 38.4615 5 no
GO:0032970 regulation of actin filament-based process 38.4615 4 no
GO:0051130 positive regulation of cellular component organization 38.4615 5 no
GO:0048523 negative regulation of cellular process 38.4615 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 30.7692 5 yes
GO:0032386 regulation of intracellular transport 30.7692 5 yes
GO:0032388 positive regulation of intracellular transport 30.7692 5 yes
GO:0033157 regulation of intracellular protein transport 30.7692 6 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 30.7692 6 yes
GO:0051222 positive regulation of protein transport 30.7692 5 yes
GO:0090316 positive regulation of intracellular protein transport 30.7692 6 yes
GO:1903829 positive regulation of protein localization 30.7692 5 yes
GO:1904951 positive regulation of establishment of protein localization 30.7692 6 yes
GO:0043412 macromolecule modification 30.7692 4 no
GO:0051246 regulation of protein metabolic process 30.7692 5 no
GO:0007015 actin filament organization 30.7692 5 no
GO:0007265 Ras protein signal transduction 30.7692 5 no
GO:0030155 regulation of cell adhesion 30.7692 4 no
GO:0044087 regulation of cellular component biogenesis 30.7692 4 no
GO:0044089 positive regulation of cellular component biogenesis 30.7692 5 no
GO:0097435 supramolecular fiber organization 30.7692 4 no
GO:0010646 regulation of cell communication 30.7692 4 no
GO:0016192 vesicle-mediated transport 30.7692 4 no
GO:0010638 positive regulation of organelle organization 30.7692 6 no
GO:0045595 regulation of cell differentiation 30.7692 4 no
GO:0006355 regulation of DNA-templated transcription 23.0769 6 yes
GO:0009889 regulation of biosynthetic process 23.0769 4 yes
GO:0009891 positive regulation of biosynthetic process 23.0769 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 23.0769 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 23.0769 6 yes
GO:0031326 regulation of cellular biosynthetic process 23.0769 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 23.0769 6 yes
GO:0045893 positive regulation of DNA-templated transcription 23.0769 7 yes
GO:0051252 regulation of RNA metabolic process 23.0769 5 yes
GO:0051254 positive regulation of RNA metabolic process 23.0769 6 yes
GO:0120031 plasma membrane bounded cell projection assembly 23.0769 6 yes
GO:1902680 positive regulation of RNA biosynthetic process 23.0769 7 yes
GO:1903506 regulation of nucleic acid-templated transcription 23.0769 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 23.0769 8 yes
GO:2001141 regulation of RNA biosynthetic process 23.0769 6 yes
GO:0009892 negative regulation of metabolic process 23.0769 4 no
GO:0010605 negative regulation of macromolecule metabolic process 23.0769 5 no
GO:0010975 regulation of neuron projection development 23.0769 7 no
GO:0031399 regulation of protein modification process 23.0769 6 no
GO:0036211 protein modification process 23.0769 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 23.0769 5 no
GO:0010591 regulation of lamellipodium assembly 23.0769 7 no
GO:0010592 positive regulation of lamellipodium assembly 23.0769 7 no
GO:0010810 regulation of cell-substrate adhesion 23.0769 5 no
GO:0022604 regulation of cell morphogenesis 23.0769 5 no
GO:0030334 regulation of cell migration 23.0769 5 no
GO:0031346 positive regulation of cell projection organization 23.0769 6 no
GO:0042127 regulation of cell population proliferation 23.0769 4 no
GO:0051046 regulation of secretion 23.0769 5 no
GO:0060491 regulation of cell projection assembly 23.0769 5 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 23.0769 6 no
GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 23.0769 6 no
GO:1902743 regulation of lamellipodium organization 23.0769 7 no
GO:1902745 positive regulation of lamellipodium organization 23.0769 7 no
GO:1903530 regulation of secretion by cell 23.0769 4 no
GO:2000145 regulation of cell motility 23.0769 4 no
GO:0008104 protein localization 23.0769 4 no
GO:0034329 cell junction assembly 23.0769 5 no
GO:0034330 cell junction organization 23.0769 4 no
GO:0034332 adherens junction organization 23.0769 6 no
GO:0045216 cell-cell junction organization 23.0769 5 no
GO:0071310 cellular response to organic substance 23.0769 4 no
GO:1901699 cellular response to nitrogen compound 23.0769 4 no
GO:0050807 regulation of synapse organization 23.0769 5 no
GO:0051495 positive regulation of cytoskeleton organization 23.0769 7 no
GO:0110053 regulation of actin filament organization 23.0769 6 no
GO:1902903 regulation of supramolecular fiber organization 23.0769 5 no
GO:1902905 positive regulation of supramolecular fiber organization 23.0769 6 no
GO:0045787 positive regulation of cell cycle 23.0769 5 no
GO:0051726 regulation of cell cycle 23.0769 4 no
GO:0006897 endocytosis 23.0769 5 no
GO:0045597 positive regulation of cell differentiation 23.0769 5 no
GO:0051094 positive regulation of developmental process 23.0769 4 no
GO:0006357 regulation of transcription by RNA polymerase II 15.3846 7 yes
GO:0030032 lamellipodium assembly 15.3846 7 yes
GO:0044782 cilium organization 15.3846 5 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 15.3846 8 yes
GO:0060271 cilium assembly 15.3846 6 yes
GO:0070925 organelle assembly 15.3846 5 yes
GO:0090304 nucleic acid metabolic process 15.3846 4 yes
GO:0097581 lamellipodium organization 15.3846 6 yes
GO:1903214 regulation of protein targeting to mitochondrion 15.3846 8 yes
GO:1903533 regulation of protein targeting 15.3846 7 yes
GO:1903747 regulation of establishment of protein localization to mitochondrion 15.3846 7 yes
GO:1903749 positive regulation of establishment of protein localization to mitochondrion 15.3846 7 yes
GO:1903955 positive regulation of protein targeting to mitochondrion 15.3846 7 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ACTC_HUMAN [view interactions] Low throughput no no
ABRA_HUMAN [view interactions] Low throughput no no
ACTS_HUMAN [view interactions] Low throughput no no
ADIP_HUMAN [view interactions] High throughput no yes
CCD33_HUMAN [view interactions] High throughput no no
BRCA1_HUMAN [view interactions] High throughput no yes
PALMD_HUMAN [view interactions] High throughput no no
TFP11_HUMAN [view interactions] High throughput no no
SNW1_HUMAN [view interactions] High throughput no yes
ABI2_HUMAN [view entry] [view interactions] High throughput yes yes
CBX8_HUMAN [view interactions] High throughput no yes
HIKES_HUMAN [view interactions] High throughput no yes
C19L2_HUMAN [view interactions] High throughput no yes
BANP_HUMAN [view interactions] High throughput no yes
CTSR1_HUMAN [view interactions] High throughput no no
ZN620_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
APEX1_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
CCNH_HUMAN [view interactions] High throughput no yes
BBS2_HUMAN [view interactions] High throughput no no
PTHB1_HUMAN [view interactions] High throughput no yes
ZN426_HUMAN [view interactions] High throughput no yes
PDLI7_HUMAN [view entry] [view interactions] High throughput yes no
AFAD_HUMAN [view interactions] High throughput no yes
MAT1_HUMAN [view interactions] High throughput no yes
LIMD1_HUMAN [view interactions] High throughput no yes
TARB1_HUMAN [view interactions] High throughput no no
GNPI1_HUMAN [view interactions] High throughput no yes
SPEB_HUMAN [view interactions] High throughput no no
ATRX_HUMAN [view entry] [view interactions] High throughput yes yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
MCM7_HUMAN [view interactions] High throughput no no
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
BMI1_HUMAN [view interactions] High throughput no yes
IKZF3_HUMAN [view interactions] High throughput no no
RAC3_HUMAN [view entry] [view interactions] Computational yes no
CDC42_HUMAN [view entry] [view interactions] Computational yes yes
ABLM1_HUMAN [view entry] [view interactions] Computational yes yes
RAC2_HUMAN [view entry] [view interactions] Computational yes yes