Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KPYR_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Plays a key role in glycolysis. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in KPYR_HUMAN
GO:0000166 nucleotide binding 72.7273 4 yes
GO:0017076 purine nucleotide binding 72.7273 5 yes
GO:0032555 purine ribonucleotide binding 72.7273 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 72.7273 4 yes
GO:0043168 anion binding 72.7273 4 yes
GO:0005524 ATP binding 45.4545 5 yes
GO:0030554 adenyl nucleotide binding 45.4545 6 yes
GO:0032559 adenyl ribonucleotide binding 45.4545 5 yes
GO:0016301 kinase activity 36.3636 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 36.3636 4 yes
GO:0043169 cation binding 36.3636 4 yes
GO:0046872 metal ion binding 36.3636 5 yes
GO:0003924 GTPase activity 27.2727 7 no
GO:0005525 GTP binding 27.2727 5 no
GO:0016462 pyrophosphatase activity 27.2727 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 27.2727 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 27.2727 6 no
GO:0019001 guanyl nucleotide binding 27.2727 6 no
GO:0032561 guanyl ribonucleotide binding 27.2727 5 no
GO:0000287 magnesium ion binding 18.1818 6 yes
GO:0004743 pyruvate kinase activity 18.1818 5 yes
GO:0030955 potassium ion binding 18.1818 7 yes
GO:0031420 alkali metal ion binding 18.1818 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in KPYR_HUMAN
GO:0048522 positive regulation of cellular process 54.5455 4 no
GO:0071310 cellular response to organic substance 45.4545 4 yes
GO:0006996 organelle organization 45.4545 4 no
GO:0007010 cytoskeleton organization 45.4545 5 no
GO:0009893 positive regulation of metabolic process 45.4545 4 no
GO:0031323 regulation of cellular metabolic process 45.4545 4 no
GO:0031325 positive regulation of cellular metabolic process 45.4545 5 no
GO:0060255 regulation of macromolecule metabolic process 45.4545 4 no
GO:0080090 regulation of primary metabolic process 45.4545 4 no
GO:0006796 phosphate-containing compound metabolic process 45.4545 4 yes
GO:0010243 response to organonitrogen compound 36.3636 4 yes
GO:0016310 phosphorylation 36.3636 5 yes
GO:1901701 cellular response to oxygen-containing compound 36.3636 4 yes
GO:0008284 positive regulation of cell population proliferation 36.3636 5 no
GO:0010604 positive regulation of macromolecule metabolic process 36.3636 5 no
GO:0010646 regulation of cell communication 36.3636 4 no
GO:0019220 regulation of phosphate metabolic process 36.3636 6 no
GO:0033043 regulation of organelle organization 36.3636 5 no
GO:0036211 protein modification process 36.3636 4 no
GO:0042127 regulation of cell population proliferation 36.3636 4 no
GO:0042325 regulation of phosphorylation 36.3636 7 no
GO:0043412 macromolecule modification 36.3636 4 no
GO:0048523 negative regulation of cellular process 36.3636 4 no
GO:0051128 regulation of cellular component organization 36.3636 4 no
GO:0051130 positive regulation of cellular component organization 36.3636 5 no
GO:0051174 regulation of phosphorus metabolic process 36.3636 5 no
GO:0051246 regulation of protein metabolic process 36.3636 5 no
GO:0009259 ribonucleotide metabolic process 27.2727 5 yes
GO:0014070 response to organic cyclic compound 27.2727 4 yes
GO:0019693 ribose phosphate metabolic process 27.2727 4 yes
GO:0032870 cellular response to hormone stimulus 27.2727 4 yes
GO:0043434 response to peptide hormone 27.2727 4 yes
GO:0071417 cellular response to organonitrogen compound 27.2727 4 yes
GO:0072521 purine-containing compound metabolic process 27.2727 4 yes
GO:1901699 cellular response to nitrogen compound 27.2727 4 yes
GO:0001932 regulation of protein phosphorylation 27.2727 7 no
GO:0002684 positive regulation of immune system process 27.2727 4 no
GO:0009966 regulation of signal transduction 27.2727 4 no
GO:0010562 positive regulation of phosphorus metabolic process 27.2727 6 no
GO:0010638 positive regulation of organelle organization 27.2727 6 no
GO:0010647 positive regulation of cell communication 27.2727 5 no
GO:0022603 regulation of anatomical structure morphogenesis 27.2727 4 no
GO:0023056 positive regulation of signaling 27.2727 4 no
GO:0030334 regulation of cell migration 27.2727 5 no
GO:0030335 positive regulation of cell migration 27.2727 6 no
GO:0031347 regulation of defense response 27.2727 5 no
GO:0031399 regulation of protein modification process 27.2727 6 no
GO:0032101 regulation of response to external stimulus 27.2727 4 no
GO:0040017 positive regulation of locomotion 27.2727 4 no
GO:0042327 positive regulation of phosphorylation 27.2727 8 no
GO:0043549 regulation of kinase activity 27.2727 5 no
GO:0044087 regulation of cellular component biogenesis 27.2727 4 no
GO:0044089 positive regulation of cellular component biogenesis 27.2727 5 no
GO:0045937 positive regulation of phosphate metabolic process 27.2727 7 no
GO:0048584 positive regulation of response to stimulus 27.2727 4 no
GO:0050776 regulation of immune response 27.2727 4 no
GO:0051338 regulation of transferase activity 27.2727 4 no
GO:0080134 regulation of response to stress 27.2727 4 no
GO:1902531 regulation of intracellular signal transduction 27.2727 5 no
GO:2000145 regulation of cell motility 27.2727 4 no
GO:2000147 positive regulation of cell motility 27.2727 5 no
GO:0009059 macromolecule biosynthetic process 27.2727 4 no
GO:1901566 organonitrogen compound biosynthetic process 27.2727 4 no
GO:0009889 regulation of biosynthetic process 27.2727 4 no
GO:0009891 positive regulation of biosynthetic process 27.2727 5 no
GO:0010468 regulation of gene expression 27.2727 6 no
GO:0010556 regulation of macromolecule biosynthetic process 27.2727 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 27.2727 6 no
GO:0010628 positive regulation of gene expression 27.2727 7 no
GO:0010720 positive regulation of cell development 27.2727 6 no
GO:0031326 regulation of cellular biosynthetic process 27.2727 5 no
GO:0031328 positive regulation of cellular biosynthetic process 27.2727 6 no
GO:0045595 regulation of cell differentiation 27.2727 4 no
GO:0045596 negative regulation of cell differentiation 27.2727 5 no
GO:0045597 positive regulation of cell differentiation 27.2727 5 no
GO:0051093 negative regulation of developmental process 27.2727 4 no
GO:0051094 positive regulation of developmental process 27.2727 4 no
GO:0051240 positive regulation of multicellular organismal process 27.2727 4 no
GO:0060284 regulation of cell development 27.2727 5 no
GO:2000026 regulation of multicellular organismal development 27.2727 4 no
GO:0042981 regulation of apoptotic process 27.2727 5 no
GO:0043067 regulation of programmed cell death 27.2727 4 no
GO:0006163 purine nucleotide metabolic process 27.2727 5 yes
GO:0006753 nucleoside phosphate metabolic process 27.2727 4 yes
GO:0009117 nucleotide metabolic process 27.2727 5 yes
GO:0009150 purine ribonucleotide metabolic process 27.2727 6 yes
GO:0009199 ribonucleoside triphosphate metabolic process 18.1818 6 yes
GO:0009205 purine ribonucleoside triphosphate metabolic process 18.1818 7 yes
GO:0009261 ribonucleotide catabolic process 18.1818 5 yes
GO:0009743 response to carbohydrate 18.1818 4 yes
GO:0009746 response to hexose 18.1818 6 yes
GO:0009749 response to glucose 18.1818 7 yes
GO:0010038 response to metal ion 18.1818 4 yes
GO:0014074 response to purine-containing compound 18.1818 5 yes
GO:0016052 carbohydrate catabolic process 18.1818 4 yes
GO:0016053 organic acid biosynthetic process 18.1818 4 yes
GO:0019362 pyridine nucleotide metabolic process 18.1818 5 yes
GO:0019364 pyridine nucleotide catabolic process 18.1818 6 yes
GO:0019752 carboxylic acid metabolic process 18.1818 5 yes
GO:0032787 monocarboxylic acid metabolic process 18.1818 6 yes
GO:0032868 response to insulin 18.1818 5 yes
GO:0032869 cellular response to insulin stimulus 18.1818 6 yes
GO:0033198 response to ATP 18.1818 4 yes
GO:0034284 response to monosaccharide 18.1818 5 yes
GO:0034655 nucleobase-containing compound catabolic process 18.1818 4 yes
GO:0036293 response to decreased oxygen levels 18.1818 4 yes
GO:0042866 pyruvate biosynthetic process 18.1818 7 yes
GO:0043436 oxoacid metabolic process 18.1818 4 yes
GO:0046031 ADP metabolic process 18.1818 7 yes
GO:0046032 ADP catabolic process 18.1818 7 yes
GO:0046034 ATP metabolic process 18.1818 7 yes
GO:0046394 carboxylic acid biosynthetic process 18.1818 5 yes
GO:0046434 organophosphate catabolic process 18.1818 4 yes
GO:0046496 nicotinamide nucleotide metabolic process 18.1818 6 yes
GO:0046683 response to organophosphorus 18.1818 4 yes
GO:0051591 response to cAMP 18.1818 4 yes
GO:0071375 cellular response to peptide hormone stimulus 18.1818 5 yes
GO:0071872 cellular response to epinephrine stimulus 18.1818 4 yes
GO:0072330 monocarboxylic acid biosynthetic process 18.1818 6 yes
GO:0072523 purine-containing compound catabolic process 18.1818 5 yes
GO:0072524 pyridine-containing compound metabolic process 18.1818 4 yes
GO:0072526 pyridine-containing compound catabolic process 18.1818 5 yes
GO:1901136 carbohydrate derivative catabolic process 18.1818 4 yes
GO:1901292 nucleoside phosphate catabolic process 18.1818 5 yes
GO:1901361 organic cyclic compound catabolic process 18.1818 4 yes
GO:1901565 organonitrogen compound catabolic process 18.1818 4 yes
GO:0006090 pyruvate metabolic process 18.1818 7 yes
GO:0006096 glycolytic process 18.1818 4 yes
GO:0006195 purine nucleotide catabolic process 18.1818 6 yes
GO:0009132 nucleoside diphosphate metabolic process 18.1818 5 yes
GO:0009134 nucleoside diphosphate catabolic process 18.1818 6 yes
GO:0009135 purine nucleoside diphosphate metabolic process 18.1818 6 yes
GO:0009137 purine nucleoside diphosphate catabolic process 18.1818 7 yes
GO:0009141 nucleoside triphosphate metabolic process 18.1818 5 yes
GO:0009144 purine nucleoside triphosphate metabolic process 18.1818 6 yes
GO:0009154 purine ribonucleotide catabolic process 18.1818 6 yes
GO:0009166 nucleotide catabolic process 18.1818 6 yes
GO:0009179 purine ribonucleoside diphosphate metabolic process 18.1818 7 yes
GO:0009181 purine ribonucleoside diphosphate catabolic process 18.1818 8 yes
GO:0009185 ribonucleoside diphosphate metabolic process 18.1818 6 yes
GO:0009191 ribonucleoside diphosphate catabolic process 18.1818 7 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
KIF23_HUMAN [view interactions] Low throughput no yes
ARHG6_HUMAN [view interactions] Low throughput no no
PAXI_HUMAN [view interactions] Low throughput no yes
PAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
KPYR_HUMAN [view entry] [view interactions] Low throughput yes no
PASK_HUMAN [view interactions] High throughput no yes
CLC4G_HUMAN [view interactions] High throughput no no
SAV1_HUMAN [view interactions] High throughput no yes
OTUD5_HUMAN [view interactions] High throughput no yes
UBP3_HUMAN [view interactions] High throughput no no
USPL1_HUMAN [view interactions] High throughput no yes
BUB1B_HUMAN [view interactions] High throughput no no
SRPK3_HUMAN [view interactions] High throughput no no
ANXA1_HUMAN [view entry] [view interactions] High throughput yes no
CPNE7_HUMAN [view interactions] High throughput no no
WWOX_HUMAN [view interactions] High throughput no yes
NT5D1_HUMAN [view interactions] High throughput no no
RASM_HUMAN [view entry] [view interactions] High throughput yes yes
CP4B1_HUMAN [view interactions] High throughput no no
NR2C2_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
CUL4A_HUMAN [view interactions] High throughput no no
KPYM_HUMAN [view interactions] High throughput no yes
CMA1A_HUMAN [view interactions] High throughput no no
SPIN4_HUMAN [view interactions] High throughput no no
UB2J2_HUMAN [view interactions] High throughput no no
TMM69_HUMAN [view interactions] High throughput no no
FCERA_HUMAN [view interactions] High throughput no yes
SBDS_HUMAN [view interactions] High throughput no yes
PCGF3_HUMAN [view interactions] High throughput no yes
RFXK_HUMAN [view interactions] High throughput no yes
S5A2_HUMAN [view interactions] High throughput no no
RSLBA_HUMAN [view interactions] High throughput no yes
PI15_HUMAN [view interactions] High throughput no no
ISX_HUMAN [view interactions] High throughput no no
LRC3B_HUMAN [view interactions] High throughput no yes
DKK2_HUMAN [view interactions] High throughput no no
DVL2_HUMAN [view interactions] High throughput no yes
CLIP1_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
TRI33_HUMAN [view interactions] High throughput no yes
TRI72_HUMAN [view interactions] High throughput no no
RL40_HUMAN [view entry] [view interactions] High throughput yes yes
EFNA3_HUMAN [view interactions] High throughput no yes
EPHA2_HUMAN [view interactions] High throughput no no
MK12_HUMAN [view interactions] High throughput no no
BRCA2_HUMAN [view interactions] High throughput no no
CSK_HUMAN [view interactions] High throughput no yes
EPHB2_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
PCNA_HUMAN [view interactions] High throughput no no
FND3B_HUMAN [view interactions] High throughput no no
EF1A2_HUMAN [view entry] [view interactions] High throughput yes yes
PUR6_HUMAN [view entry] [view interactions] High throughput yes yes
TRI23_HUMAN [view interactions] High throughput no yes