Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KPYR_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Plays a key role in glycolysis. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in KPYR_HUMAN
GO:0017076 purine nucleotide binding 51.3514 4 yes
GO:0032555 purine ribonucleotide binding 51.3514 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 51.3514 4 yes
GO:0005524 ATP binding 43.2432 5 yes
GO:0030554 adenyl nucleotide binding 43.2432 5 yes
GO:0032559 adenyl ribonucleotide binding 43.2432 5 yes
GO:0046872 metal ion binding 40.5405 4 yes
GO:0016301 kinase activity 35.1351 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 21.6216 4 yes
GO:0000287 magnesium ion binding 18.9189 5 yes
GO:0004743 pyruvate kinase activity 5.4054 5 yes
GO:0030955 potassium ion binding 5.4054 6 yes
GO:0031420 alkali metal ion binding 5.4054 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in KPYR_HUMAN
GO:0006796 phosphate-containing compound metabolic process 78.3784 4 yes
GO:0009117 nucleotide metabolic process 70.2703 5 yes
GO:0006753 nucleoside phosphate metabolic process 70.2703 4 yes
GO:0019693 ribose phosphate metabolic process 64.8649 4 yes
GO:0072521 purine-containing compound metabolic process 62.1622 4 yes
GO:0006163 purine nucleotide metabolic process 62.1622 5 yes
GO:0009150 purine ribonucleotide metabolic process 59.4595 6 yes
GO:0009259 ribonucleotide metabolic process 59.4595 5 yes
GO:0019752 carboxylic acid metabolic process 54.0541 5 yes
GO:0043436 oxoacid metabolic process 54.0541 4 yes
GO:0009132 nucleoside diphosphate metabolic process 51.3514 5 yes
GO:0009141 nucleoside triphosphate metabolic process 51.3514 5 yes
GO:0009144 purine nucleoside triphosphate metabolic process 51.3514 6 yes
GO:0009199 ribonucleoside triphosphate metabolic process 51.3514 6 yes
GO:0009205 purine ribonucleoside triphosphate metabolic process 51.3514 7 yes
GO:0032787 monocarboxylic acid metabolic process 51.3514 6 yes
GO:0006090 pyruvate metabolic process 51.3514 7 yes
GO:0016310 phosphorylation 48.6486 5 yes
GO:0009135 purine nucleoside diphosphate metabolic process 45.9459 6 yes
GO:0009185 ribonucleoside diphosphate metabolic process 45.9459 6 yes
GO:0009179 purine ribonucleoside diphosphate metabolic process 43.2432 7 yes
GO:0046031 ADP metabolic process 43.2432 7 yes
GO:0046939 nucleotide phosphorylation 43.2432 6 yes
GO:0006165 nucleoside diphosphate phosphorylation 43.2432 6 yes
GO:0016052 carbohydrate catabolic process 40.5405 4 yes
GO:0046034 ATP metabolic process 40.5405 7 yes
GO:0006096 glycolytic process 40.5405 5 yes
GO:0006757 ATP generation from ADP 40.5405 4 yes
GO:0090407 organophosphate biosynthetic process 37.8378 4 yes
GO:1901137 carbohydrate derivative biosynthetic process 37.8378 4 yes
GO:0019318 hexose metabolic process 37.8378 4 no
GO:0006006 glucose metabolic process 35.1351 5 no
GO:0048522 positive regulation of cellular process 35.1351 4 no
GO:0044271 cellular nitrogen compound biosynthetic process 32.4324 4 yes
GO:1901362 organic cyclic compound biosynthetic process 32.4324 4 yes
GO:0060255 regulation of macromolecule metabolic process 32.4324 4 no
GO:0009165 nucleotide biosynthetic process 29.7297 6 yes
GO:0018130 heterocycle biosynthetic process 29.7297 4 yes
GO:0019438 aromatic compound biosynthetic process 29.7297 4 yes
GO:0034654 nucleobase-containing compound biosynthetic process 29.7297 4 yes
GO:0046390 ribose phosphate biosynthetic process 29.7297 5 yes
GO:1901293 nucleoside phosphate biosynthetic process 29.7297 5 yes
GO:1901566 organonitrogen compound biosynthetic process 29.7297 4 yes
GO:0031323 regulation of cellular metabolic process 29.7297 4 no
GO:0048523 negative regulation of cellular process 29.7297 4 no
GO:0080090 regulation of primary metabolic process 29.7297 4 no
GO:0072522 purine-containing compound biosynthetic process 27.0270 5 yes
GO:0051171 regulation of nitrogen compound metabolic process 27.0270 4 no
GO:0006164 purine nucleotide biosynthetic process 27.0270 6 yes
GO:0009152 purine ribonucleotide biosynthetic process 24.3243 7 yes
GO:0009260 ribonucleotide biosynthetic process 24.3243 6 yes
GO:0009893 positive regulation of metabolic process 24.3243 4 no
GO:0010941 regulation of cell death 21.6216 4 no
GO:0010468 regulation of gene expression 21.6216 5 no
GO:0010604 positive regulation of macromolecule metabolic process 21.6216 5 no
GO:0010646 regulation of cell communication 21.6216 4 no
GO:0031325 positive regulation of cellular metabolic process 21.6216 5 no
GO:0071310 cellular response to organic substance 18.9189 4 yes
GO:0009142 nucleoside triphosphate biosynthetic process 16.2162 6 yes
GO:0009145 purine nucleoside triphosphate biosynthetic process 13.5135 7 yes
GO:0009201 ribonucleoside triphosphate biosynthetic process 13.5135 7 yes
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 13.5135 8 yes
GO:0014070 response to organic cyclic compound 13.5135 4 yes
GO:0010038 response to metal ion 10.8108 4 yes
GO:0010243 response to organonitrogen compound 10.8108 4 yes
GO:1901652 response to peptide 10.8108 4 yes
GO:1901701 cellular response to oxygen-containing compound 10.8108 4 yes
GO:0009743 response to carbohydrate 8.1081 4 yes
GO:0009746 response to hexose 8.1081 6 yes
GO:0009749 response to glucose 8.1081 7 yes
GO:0031667 response to nutrient levels 8.1081 4 yes
GO:0032870 cellular response to hormone stimulus 8.1081 4 yes
GO:0034284 response to monosaccharide 8.1081 5 yes
GO:0036293 response to decreased oxygen levels 8.1081 4 yes
GO:0043434 response to peptide hormone 8.1081 4 yes
GO:0071407 cellular response to organic cyclic compound 8.1081 5 yes
GO:0071417 cellular response to organonitrogen compound 8.1081 4 yes
GO:1901653 cellular response to peptide 8.1081 5 yes
GO:1901699 cellular response to nitrogen compound 8.1081 4 yes
GO:0010226 response to lithium ion 5.4054 5 yes
GO:0014074 response to purine-containing compound 5.4054 5 yes
GO:0016053 organic acid biosynthetic process 5.4054 4 yes
GO:0032868 response to insulin 5.4054 5 yes
GO:0032869 cellular response to insulin stimulus 5.4054 6 yes
GO:0033198 response to ATP 5.4054 4 yes
GO:0042866 pyruvate biosynthetic process 5.4054 7 yes
GO:0046394 carboxylic acid biosynthetic process 5.4054 5 yes
GO:0046683 response to organophosphorus 5.4054 4 yes
GO:0051591 response to cAMP 5.4054 4 yes
GO:0071375 cellular response to peptide hormone stimulus 5.4054 5 yes
GO:0071867 response to monoamine 5.4054 5 yes
GO:0071868 cellular response to monoamine stimulus 5.4054 5 yes
GO:0071869 response to catecholamine 5.4054 4 yes
GO:0071870 cellular response to catecholamine stimulus 5.4054 5 yes
GO:0071871 response to epinephrine 5.4054 5 yes
GO:0071872 cellular response to epinephrine stimulus 5.4054 6 yes
GO:0072330 monocarboxylic acid biosynthetic process 5.4054 6 yes
GO:0006754 ATP biosynthetic process 5.4054 8 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
KIF23_HUMAN [view interactions] Low throughput no yes
ARHG6_HUMAN [view interactions] Low throughput no no
PAXI_HUMAN [view interactions] Low throughput no yes
PAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
KPYR_HUMAN [view entry] [view interactions] Low throughput yes no
PASK_HUMAN [view interactions] High throughput no yes
CLC4G_HUMAN [view interactions] High throughput no no
SAV1_HUMAN [view interactions] High throughput no yes
OTUD5_HUMAN [view interactions] High throughput no yes
UBP3_HUMAN [view interactions] High throughput no no
USPL1_HUMAN [view interactions] High throughput no yes
BUB1B_HUMAN [view interactions] High throughput no no
SRPK3_HUMAN [view interactions] High throughput no no
ANXA1_HUMAN [view entry] [view interactions] High throughput yes no
CPNE7_HUMAN [view interactions] High throughput no no
WWOX_HUMAN [view interactions] High throughput no yes
NT5D1_HUMAN [view interactions] High throughput no no
RASM_HUMAN [view entry] [view interactions] High throughput yes yes
CP4B1_HUMAN [view interactions] High throughput no no
NR2C2_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
CUL4A_HUMAN [view interactions] High throughput no no
KPYM_HUMAN [view interactions] High throughput no yes
ODF3A_HUMAN [view interactions] High throughput no no
SPIN4_HUMAN [view interactions] High throughput no no
UB2J2_HUMAN [view interactions] High throughput no no
TMM69_HUMAN [view interactions] High throughput no no
FCERA_HUMAN [view interactions] High throughput no yes
SBDS_HUMAN [view interactions] High throughput no yes
PCGF3_HUMAN [view interactions] High throughput no yes
RFXK_HUMAN [view interactions] High throughput no yes
S5A2_HUMAN [view interactions] High throughput no no
RSLBA_HUMAN [view interactions] High throughput no yes
PI15_HUMAN [view interactions] High throughput no no
ISX_HUMAN [view interactions] High throughput no no
LRC3B_HUMAN [view interactions] High throughput no yes
DKK2_HUMAN [view interactions] High throughput no no
DVL2_HUMAN [view interactions] High throughput no yes
CLIP1_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA2_HUMAN [view interactions] High throughput no no
MK12_HUMAN [view interactions] High throughput no no
BRCA2_HUMAN [view interactions] High throughput no no
CSK_HUMAN [view interactions] High throughput no yes
EPHB2_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
PCNA_HUMAN [view interactions] High throughput no no
EF1A2_HUMAN [view entry] [view interactions] High throughput yes yes
PUR6_HUMAN [view entry] [view interactions] High throughput yes yes
ITPA_HUMAN [view interactions] Computational no yes
NDKA_HUMAN [view entry] [view interactions] Computational yes yes
GCH1_HUMAN [view interactions] Computational no no
RIR2B_HUMAN [view interactions] Computational no yes
MDHM_HUMAN [view entry] [view interactions] Computational yes yes
NDKB_HUMAN [view entry] [view interactions] Computational yes yes
LDHC_HUMAN [view interactions] Computational no no
ENTP6_HUMAN [view interactions] Computational no yes
RIR2_HUMAN [view interactions] Computational no no
G6PD_HUMAN [view entry] [view interactions] Computational yes no
GLCTK_HUMAN [view interactions] Computational no yes
PCKGC_HUMAN [view interactions] Computational no no
KGUA_HUMAN [view entry] [view interactions] Computational yes yes
MAOM_HUMAN [view interactions] Computational no yes
NTPCR_HUMAN [view interactions] Computational no yes
G3P_HUMAN [view entry] [view interactions] Computational yes yes
ENTP2_HUMAN [view interactions] Computational no yes
ENOA_HUMAN [view entry] [view interactions] Computational yes yes
ODPA_HUMAN [view entry] [view interactions] Computational yes yes
ENTP4_HUMAN [view interactions] Computational no yes
PFKAP_HUMAN [view entry] [view interactions] Computational yes yes
TKTL1_HUMAN [view interactions] Computational no no
PCKGM_HUMAN [view interactions] Computational no no
KAD9_HUMAN [view interactions] Computational no yes
PGAM1_HUMAN [view entry] [view interactions] Computational yes yes
PGK2_HUMAN [view interactions] Computational no no
ENO4_HUMAN [view interactions] Computational no no
ALDOC_HUMAN [view entry] [view interactions] Computational yes yes
PYC_HUMAN [view entry] [view interactions] Computational yes yes
ODPB_HUMAN [view entry] [view interactions] Computational yes yes
LDHB_HUMAN [view entry] [view interactions] Computational yes yes
G6PE_HUMAN [view interactions] Computational no yes
RIR1_HUMAN [view entry] [view interactions] Computational yes yes
ENTP3_HUMAN [view interactions] Computational no no
TKT_HUMAN [view entry] [view interactions] Computational yes yes
MAON_HUMAN [view interactions] Computational no yes
LDH6B_HUMAN [view interactions] Computational no no
TKTL2_HUMAN [view interactions] Computational no no
LDHA_HUMAN [view entry] [view interactions] Computational yes yes
G3PT_HUMAN [view interactions] Computational no no
CANT1_HUMAN [view interactions] Computational no yes
PFKAM_HUMAN [view entry] [view interactions] Computational yes yes
TPIS_HUMAN [view entry] [view interactions] Computational yes yes
ENPP3_HUMAN [view interactions] Computational no no
MESH1_HUMAN [view interactions] Computational no yes
NDK3_HUMAN [view entry] [view interactions] Computational yes yes
TALDO_HUMAN [view entry] [view interactions] Computational yes no
LDH6A_HUMAN [view interactions] Computational no no
ENTP1_HUMAN [view interactions] Computational no yes
NDK7_HUMAN [view interactions] Computational no yes
LDHD_HUMAN [view interactions] Computational no yes
DEOC_HUMAN [view interactions] Computational no no
A0A2U3TZM8_HUMAN [view interactions] Computational no no
MAOX_HUMAN [view interactions] Computational no yes
KAD3_HUMAN [view entry] [view interactions] Computational yes yes
ODPAT_HUMAN [view interactions] Computational no no
PFKAL_HUMAN [view entry] [view interactions] Computational yes yes
NDKM_HUMAN [view interactions] Computational no yes
AP4A_HUMAN [view interactions] Computational no no
ENOB_HUMAN [view entry] [view interactions] Computational yes no
PGAM2_HUMAN [view entry] [view interactions] Computational yes no
ENTP8_HUMAN [view interactions] Computational no no
MLXPL_HUMAN [view interactions] Computational no no
PGK1_HUMAN [view entry] [view interactions] Computational yes yes
ENTP5_HUMAN [view interactions] Computational no yes
ENOG_HUMAN [view entry] [view interactions] Computational yes yes