K0408_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in K0408_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 41.6667 | 4 | no |
| GO:0019901 | protein kinase binding | 33.3333 | 5 | no |
| GO:0003723 | RNA binding | 25.0000 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in K0408_HUMAN |
|---|---|---|---|---|
| GO:0048523 | negative regulation of cellular process | 75.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 62.5000 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 62.5000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 62.5000 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 54.1667 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 54.1667 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 54.1667 | 4 | no |
| GO:0010646 | regulation of cell communication | 45.8333 | 4 | no |
| GO:0006996 | organelle organization | 45.8333 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 41.6667 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 41.6667 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 41.6667 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 41.6667 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 41.6667 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 41.6667 | 5 | no |
| GO:0007010 | cytoskeleton organization | 41.6667 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | no |
| GO:0033043 | regulation of organelle organization | 33.3333 | 5 | no |
| GO:0009966 | regulation of signal transduction | 33.3333 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.3333 | 5 | no |
| GO:0010941 | regulation of cell death | 33.3333 | 4 | no |
| GO:0008104 | protein localization | 33.3333 | 4 | no |
| GO:0030030 | cell projection organization | 33.3333 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 33.3333 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 29.1667 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 29.1667 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 29.1667 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.1667 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 29.1667 | 5 | no |
| GO:0031399 | regulation of protein modification process | 29.1667 | 6 | no |
| GO:0051049 | regulation of transport | 29.1667 | 4 | no |
| GO:0060548 | negative regulation of cell death | 29.1667 | 5 | no |
| GO:0051338 | regulation of transferase activity | 29.1667 | 4 | no |
| GO:0022607 | cellular component assembly | 29.1667 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 29.1667 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 25.0000 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 25.0000 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 25.0000 | 6 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 25.0000 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.0000 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 25.0000 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 25.0000 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 25.0000 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 25.0000 | 7 | no |
| GO:0019220 | regulation of phosphate metabolic process | 25.0000 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 25.0000 | 7 | no |
| GO:0043549 | regulation of kinase activity | 25.0000 | 5 | no |
| GO:0045859 | regulation of protein kinase activity | 25.0000 | 6 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 25.0000 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 25.0000 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 25.0000 | 6 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 25.0000 | 4 | no |
| GO:0097435 | supramolecular fiber organization | 25.0000 | 4 | no |
| GO:0009894 | regulation of catabolic process | 25.0000 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 25.0000 | 5 | no |
| GO:0010975 | regulation of neuron projection development | 20.8333 | 7 | no |
| GO:0043066 | negative regulation of apoptotic process | 20.8333 | 7 | no |
| GO:0043069 | negative regulation of programmed cell death | 20.8333 | 6 | no |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 20.8333 | 6 | no |
| GO:0051050 | positive regulation of transport | 20.8333 | 4 | no |
| GO:0051253 | negative regulation of RNA metabolic process | 20.8333 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 20.8333 | 5 | no |
| GO:0001933 | negative regulation of protein phosphorylation | 20.8333 | 8 | no |
| GO:0006886 | intracellular protein transport | 20.8333 | 4 | no |
| GO:0010563 | negative regulation of phosphorus metabolic process | 20.8333 | 6 | no |
| GO:0015031 | protein transport | 20.8333 | 4 | no |
| GO:0031400 | negative regulation of protein modification process | 20.8333 | 7 | no |
| GO:0042326 | negative regulation of phosphorylation | 20.8333 | 8 | no |
| GO:0045936 | negative regulation of phosphate metabolic process | 20.8333 | 7 | no |
| GO:0071702 | organic substance transport | 20.8333 | 4 | no |
| GO:0071705 | nitrogen compound transport | 20.8333 | 4 | no |
| GO:0010638 | positive regulation of organelle organization | 20.8333 | 6 | no |
| GO:0016192 | vesicle-mediated transport | 20.8333 | 4 | no |
| GO:0010970 | transport along microtubule | 20.8333 | 4 | no |
| GO:0030705 | cytoskeleton-dependent intracellular transport | 20.8333 | 4 | no |
| GO:0099111 | microtubule-based transport | 20.8333 | 4 | no |
| GO:0032990 | cell part morphogenesis | 20.8333 | 4 | no |
| GO:0048858 | cell projection morphogenesis | 20.8333 | 5 | no |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in K0408_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 12.5000 | 3 | no |
| DOID:0050155 | sensory system disease | 8.3333 | 3 | no |
| DOID:0050563 | nonsyndromic deafness | 8.3333 | 5 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 8.3333 | 6 | no |
| DOID:2742 | auditory system disease | 8.3333 | 4 | no |
| DOID:440 | neuromuscular disease | 8.3333 | 5 | no |
| DOID:574 | peripheral nervous system disease | 8.3333 | 3 | no |
| DOID:870 | neuropathy | 8.3333 | 4 | no |
| DOID:0111198 | autosomal dominant distal hereditary motor neuronopathy | 8.3333 | 7 | no |
| DOID:12377 | spinal muscular atrophy | 8.3333 | 6 | no |
| DOID:1289 | neurodegenerative disease | 8.3333 | 4 | no |
| DOID:231 | motor neuron disease | 8.3333 | 5 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFD1_HUMAN | [view interactions] | High throughput | no | yes |
| TLE1_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| ANM6_HUMAN | [view interactions] | High throughput | no | yes |
| CD3Z_HUMAN | [view interactions] | High throughput | no | no |
| VINEX_HUMAN | [view interactions] | High throughput | no | no |
| NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSF2B_HUMAN | [view interactions] | High throughput | no | yes |
| ABI3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PHF1_HUMAN | [view interactions] | High throughput | no | yes |
| RPC3_HUMAN | [view interactions] | High throughput | no | yes |
| FRS3_HUMAN | [view interactions] | High throughput | no | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDOR1_HUMAN | [view interactions] | High throughput | no | yes |
| P55G_HUMAN | [view interactions] | High throughput | no | yes |
| CARD9_HUMAN | [view interactions] | High throughput | no | no |
| GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NFL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PECA1_HUMAN | [view interactions] | High throughput | no | no |
| PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF11_HUMAN | [view interactions] | High throughput | no | no |
| NUP58_HUMAN | [view interactions] | High throughput | no | yes |
| JPH3_HUMAN | [view interactions] | High throughput | no | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP72_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEX11_HUMAN | [view interactions] | High throughput | no | no |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGAB_HUMAN | [view interactions] | High throughput | no | no |
| MDFI_HUMAN | [view interactions] | High throughput | no | no |
| TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
| BEGIN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| CC85B_HUMAN | [view interactions] | High throughput | no | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1C15_HUMAN | [view interactions] | High throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| TRI55_HUMAN | [view interactions] | High throughput | no | no |
| ZDH17_HUMAN | [view interactions] | High throughput | no | yes |
| MTG8_HUMAN | [view interactions] | High throughput | no | yes |
| UBS3A_HUMAN | [view interactions] | High throughput | no | no |
| CBY2_HUMAN | [view interactions] | High throughput | no | no |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| SETD2_HUMAN | [view interactions] | High throughput | no | yes |
| LPP_HUMAN | [view interactions] | High throughput | no | yes |
| USP9Y_HUMAN | [view interactions] | High throughput | no | no |
| SPT6H_HUMAN | [view interactions] | High throughput | no | yes |
| PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PARN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX5_HUMAN | [view interactions] | High throughput | no | yes |
| DDX49_HUMAN | [view interactions] | High throughput | no | no |
| FOCAD_HUMAN | [view interactions] | High throughput | no | no |
| CMS1_HUMAN | [view interactions] | High throughput | no | yes |
| NOL6_HUMAN | [view interactions] | High throughput | no | no |
| MAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMXL1_HUMAN | [view interactions] | High throughput | no | yes |
| PHKG2_HUMAN | [view interactions] | High throughput | no | no |
| UTP11_HUMAN | [view interactions] | High throughput | no | yes |
| RBM6_HUMAN | [view interactions] | High throughput | no | yes |