Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CBR3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro). [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CBR3_HUMAN
GO:0003723 RNA binding 33.3333 4 no
GO:0004090 carbonyl reductase (NADPH) activity 22.2222 5 yes
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 22.2222 4 yes
GO:0031625 ubiquitin protein ligase binding 22.2222 5 no
GO:0044389 ubiquitin-like protein ligase binding 22.2222 4 no
GO:0046982 protein heterodimerization activity 22.2222 4 no
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 22.2222 4 no
GO:0035091 phosphatidylinositol binding 22.2222 4 no
GO:1901981 phosphatidylinositol phosphate binding 22.2222 5 no
GO:1902936 phosphatidylinositol bisphosphate binding 22.2222 6 no
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 22.2222 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in CBR3_HUMAN
GO:0048522 positive regulation of cellular process 44.4444 4 no
GO:0009966 regulation of signal transduction 33.3333 4 no
GO:0010646 regulation of cell communication 33.3333 4 no
GO:1902531 regulation of intracellular signal transduction 33.3333 5 no
GO:0008104 protein localization 33.3333 4 no
GO:0015031 protein transport 33.3333 4 no
GO:0031323 regulation of cellular metabolic process 33.3333 4 no
GO:0048523 negative regulation of cellular process 33.3333 4 no
GO:0071702 organic substance transport 33.3333 4 no
GO:0071705 nitrogen compound transport 33.3333 4 no
GO:0009057 macromolecule catabolic process 22.2222 4 no
GO:0016567 protein ubiquitination 22.2222 7 no
GO:0019941 modification-dependent protein catabolic process 22.2222 6 no
GO:0032446 protein modification by small protein conjugation 22.2222 6 no
GO:0036211 protein modification process 22.2222 4 no
GO:0043412 macromolecule modification 22.2222 4 no
GO:0043632 modification-dependent macromolecule catabolic process 22.2222 5 no
GO:0044265 cellular macromolecule catabolic process 22.2222 4 no
GO:0051603 proteolysis involved in protein catabolic process 22.2222 5 no
GO:0070647 protein modification by small protein conjugation or removal 22.2222 5 no
GO:0007264 small GTPase mediated signal transduction 22.2222 4 no
GO:0007265 Ras protein signal transduction 22.2222 5 no
GO:0030030 cell projection organization 22.2222 4 no
GO:0120036 plasma membrane bounded cell projection organization 22.2222 5 no
GO:0009893 positive regulation of metabolic process 22.2222 4 no
GO:0031325 positive regulation of cellular metabolic process 22.2222 5 no
GO:0006996 organelle organization 22.2222 4 no
GO:0009967 positive regulation of signal transduction 22.2222 5 no
GO:0010647 positive regulation of cell communication 22.2222 5 no
GO:0023056 positive regulation of signaling 22.2222 4 no
GO:0048584 positive regulation of response to stimulus 22.2222 4 no
GO:0048585 negative regulation of response to stimulus 22.2222 4 no
GO:0080134 regulation of response to stress 22.2222 4 no
GO:1902533 positive regulation of intracellular signal transduction 22.2222 6 no
GO:0001558 regulation of cell growth 22.2222 4 no
GO:0022607 cellular component assembly 22.2222 4 no
GO:0051128 regulation of cellular component organization 22.2222 4 no
GO:0006605 protein targeting 22.2222 5 no
GO:0006886 intracellular protein transport 22.2222 4 no
GO:0007346 regulation of mitotic cell cycle 22.2222 5 no
GO:0009892 negative regulation of metabolic process 22.2222 4 no
GO:0010605 negative regulation of macromolecule metabolic process 22.2222 5 no
GO:0019220 regulation of phosphate metabolic process 22.2222 6 no
GO:0021762 substantia nigra development 22.2222 4 no
GO:0031324 negative regulation of cellular metabolic process 22.2222 5 no
GO:0031399 regulation of protein modification process 22.2222 6 no
GO:0033365 protein localization to organelle 22.2222 5 no
GO:0051049 regulation of transport 22.2222 4 no
GO:0051050 positive regulation of transport 22.2222 4 no
GO:0051051 negative regulation of transport 22.2222 4 no
GO:0051171 regulation of nitrogen compound metabolic process 22.2222 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 22.2222 5 no
GO:0051174 regulation of phosphorus metabolic process 22.2222 5 no
GO:0051246 regulation of protein metabolic process 22.2222 5 no
GO:0051248 negative regulation of protein metabolic process 22.2222 6 no
GO:0051726 regulation of cell cycle 22.2222 4 no
GO:0060255 regulation of macromolecule metabolic process 22.2222 4 no
GO:0080090 regulation of primary metabolic process 22.2222 4 no
GO:0006508 proteolysis 22.2222 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ELF3_HUMAN [view interactions] Low throughput no no
UBP3_HUMAN [view interactions] High throughput no no
GBRL1_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view interactions] High throughput no no
CCNL2_HUMAN [view interactions] High throughput no yes
CBR1_HUMAN [view entry] [view interactions] High throughput yes yes
RS10_HUMAN [view entry] [view interactions] High throughput yes yes
LDLR_HUMAN [view interactions] High throughput no yes
BTBD9_HUMAN [view interactions] High throughput no yes
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
NEK4_HUMAN [view interactions] High throughput no yes
IMP1L_HUMAN [view interactions] High throughput no yes
IMP2L_HUMAN [view interactions] High throughput no yes
HMGA2_HUMAN [view interactions] High throughput no yes
SGK1_HUMAN [view interactions] High throughput no yes
SDCB1_HUMAN [view entry] [view interactions] High throughput yes yes
ARI2_HUMAN [view interactions] High throughput no no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
DCNL1_HUMAN [view interactions] High throughput no yes
BICD2_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
ABCE1_HUMAN [view interactions] High throughput no yes
KI67_HUMAN [view interactions] High throughput no no
SHRPN_HUMAN [view entry] [view interactions] High throughput yes yes
RIOK1_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
SARAF_HUMAN [view interactions] High throughput no no
PINK1_HUMAN [view interactions] High throughput no yes
SSUH2_HUMAN [view interactions] High throughput no no
UPK1A_HUMAN [view interactions] High throughput no no
CCR1_HUMAN [view interactions] High throughput no no
MBNL1_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
MSS4_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
TBB5_HUMAN [view interactions] High throughput no yes
CP2AD_HUMAN [view interactions] Computational no no
CP2A6_HUMAN [view interactions] Computational no no
PGES2_HUMAN [view interactions] Computational no yes
PTGES_HUMAN [view interactions] Computational no no
CBR4_HUMAN [view interactions] Computational no yes
CP2E1_HUMAN [view interactions] Computational no no
CP1A1_HUMAN [view interactions] Computational no yes