Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CBR3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro). [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CBR3_HUMAN
GO:0031625 ubiquitin protein ligase binding 30.7692 5 no
GO:0044389 ubiquitin-like protein ligase binding 30.7692 4 no
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 23.0769 4 yes
GO:0043168 anion binding 23.0769 4 yes
GO:0003723 RNA binding 23.0769 4 no
GO:0000166 nucleotide binding 15.3846 4 yes
GO:0004090 carbonyl reductase (NADPH) activity 15.3846 5 yes
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 15.3846 4 yes
GO:0017076 purine nucleotide binding 15.3846 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in CBR3_HUMAN
GO:0009966 regulation of signal transduction 46.1538 4 no
GO:0010646 regulation of cell communication 46.1538 4 no
GO:1902531 regulation of intracellular signal transduction 46.1538 5 no
GO:0006996 organelle organization 38.4615 4 no
GO:0009893 positive regulation of metabolic process 38.4615 4 no
GO:0022607 cellular component assembly 38.4615 4 no
GO:0048523 negative regulation of cellular process 38.4615 4 no
GO:0060255 regulation of macromolecule metabolic process 38.4615 4 no
GO:0080090 regulation of primary metabolic process 38.4615 4 no
GO:0008104 protein localization 38.4615 4 no
GO:0048522 positive regulation of cellular process 38.4615 4 no
GO:0048585 negative regulation of response to stimulus 30.7692 4 no
GO:0051246 regulation of protein metabolic process 30.7692 5 no
GO:0006508 proteolysis 30.7692 4 no
GO:0031323 regulation of cellular metabolic process 30.7692 4 no
GO:0036211 protein modification process 30.7692 4 no
GO:0043412 macromolecule modification 30.7692 4 no
GO:0048584 positive regulation of response to stimulus 30.7692 4 no
GO:0007010 cytoskeleton organization 23.0769 5 no
GO:0009968 negative regulation of signal transduction 23.0769 5 no
GO:0010604 positive regulation of macromolecule metabolic process 23.0769 5 no
GO:0010648 negative regulation of cell communication 23.0769 5 no
GO:0023057 negative regulation of signaling 23.0769 4 no
GO:0043408 regulation of MAPK cascade 23.0769 6 no
GO:0043933 protein-containing complex organization 23.0769 4 no
GO:0051247 positive regulation of protein metabolic process 23.0769 6 no
GO:0065003 protein-containing complex assembly 23.0769 5 no
GO:1902532 negative regulation of intracellular signal transduction 23.0769 6 no
GO:0001558 regulation of cell growth 23.0769 4 no
GO:0007005 mitochondrion organization 23.0769 5 no
GO:0007268 chemical synaptic transmission 23.0769 7 no
GO:0009057 macromolecule catabolic process 23.0769 4 no
GO:0009892 negative regulation of metabolic process 23.0769 4 no
GO:0009967 positive regulation of signal transduction 23.0769 5 no
GO:0010605 negative regulation of macromolecule metabolic process 23.0769 5 no
GO:0010647 positive regulation of cell communication 23.0769 5 no
GO:0016567 protein ubiquitination 23.0769 8 no
GO:0019220 regulation of phosphate metabolic process 23.0769 6 no
GO:0019941 modification-dependent protein catabolic process 23.0769 6 no
GO:0022411 cellular component disassembly 23.0769 4 no
GO:0023056 positive regulation of signaling 23.0769 4 no
GO:0031324 negative regulation of cellular metabolic process 23.0769 5 no
GO:0031325 positive regulation of cellular metabolic process 23.0769 5 no
GO:0031399 regulation of protein modification process 23.0769 6 no
GO:0032446 protein modification by small protein conjugation 23.0769 7 no
GO:0033365 protein localization to organelle 23.0769 5 no
GO:0043632 modification-dependent macromolecule catabolic process 23.0769 5 no
GO:0043687 post-translational protein modification 23.0769 5 no
GO:0051049 regulation of transport 23.0769 4 no
GO:0051050 positive regulation of transport 23.0769 4 no
GO:0051051 negative regulation of transport 23.0769 4 no
GO:0051128 regulation of cellular component organization 23.0769 4 no
GO:0051174 regulation of phosphorus metabolic process 23.0769 5 no
GO:0051603 proteolysis involved in protein catabolic process 23.0769 5 no
GO:0070647 protein modification by small protein conjugation or removal 23.0769 6 no
GO:0080134 regulation of response to stress 23.0769 4 no
GO:0098916 anterograde trans-synaptic signaling 23.0769 6 no
GO:0099536 synaptic signaling 23.0769 4 no
GO:0099537 trans-synaptic signaling 23.0769 5 no
GO:1902533 positive regulation of intracellular signal transduction 23.0769 6 no
GO:0006605 protein targeting 23.0769 4 no
GO:0141124 intracellular signaling cassette 23.0769 4 no
GO:0006775 fat-soluble vitamin metabolic process 15.3846 4 yes
GO:0042373 vitamin K metabolic process 15.3846 4 yes
GO:0050890 cognition 15.3846 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ELF3_HUMAN [view interactions] Low throughput no no
UBP3_HUMAN [view interactions] High throughput no no
GBRL1_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view entry] [view interactions] High throughput yes no
LDLR_HUMAN [view interactions] High throughput no yes
RS10_HUMAN [view entry] [view interactions] High throughput yes yes
CBR1_HUMAN [view entry] [view interactions] High throughput yes yes
CCNL2_HUMAN [view interactions] High throughput no yes
BTBD9_HUMAN [view interactions] High throughput no yes
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
NEK4_HUMAN [view interactions] High throughput no yes
IMP1L_HUMAN [view interactions] High throughput no yes
IMP2L_HUMAN [view interactions] High throughput no yes
ZBT18_HUMAN [view interactions] High throughput no yes
HMGA2_HUMAN [view interactions] High throughput no yes
SGK1_HUMAN [view interactions] High throughput no yes
SDCB1_HUMAN [view entry] [view interactions] High throughput yes yes
ARI2_HUMAN [view interactions] High throughput no no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
DCNL1_HUMAN [view interactions] High throughput no yes
BICD2_HUMAN [view interactions] High throughput no yes
RANB9_HUMAN [view entry] [view interactions] High throughput yes yes
S10AA_HUMAN [view interactions] High throughput no no
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
ABCE1_HUMAN [view interactions] High throughput no yes
KI67_HUMAN [view interactions] High throughput no no
SHRPN_HUMAN [view entry] [view interactions] High throughput yes yes
RIOK1_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
SARAF_HUMAN [view interactions] High throughput no no
PINK1_HUMAN [view interactions] High throughput no yes
SSUH2_HUMAN [view interactions] High throughput no no
UPK1A_HUMAN [view interactions] High throughput no no
CCR1_HUMAN [view interactions] High throughput no no
MBNL1_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
MSS4_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
TBB5_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no