Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

IP3KA_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in IP3KA_HUMAN
GO:0019900 kinase binding 47.0588 4 no
GO:0019901 protein kinase binding 47.0588 5 no
GO:0043169 cation binding 41.1765 4 no
GO:0046872 metal ion binding 41.1765 5 no
GO:0043168 anion binding 35.2941 4 yes
GO:0000166 nucleotide binding 29.4118 4 yes
GO:0005524 ATP binding 29.4118 5 yes
GO:0017076 purine nucleotide binding 29.4118 5 yes
GO:0030554 adenyl nucleotide binding 29.4118 6 yes
GO:0032555 purine ribonucleotide binding 29.4118 4 yes
GO:0032559 adenyl ribonucleotide binding 29.4118 5 yes
GO:0035639 purine ribonucleoside triphosphate binding 29.4118 4 yes
GO:0005509 calcium ion binding 29.4118 6 no
GO:0016301 kinase activity 23.5294 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 23.5294 4 yes
GO:0004674 protein serine/threonine kinase activity 17.6471 4 yes
GO:0004683 calmodulin-dependent protein kinase activity 11.7647 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in IP3KA_HUMAN
GO:0010646 regulation of cell communication 76.4706 4 yes
GO:0048522 positive regulation of cellular process 76.4706 4 yes
GO:0009966 regulation of signal transduction 58.8235 4 no
GO:0031323 regulation of cellular metabolic process 58.8235 4 no
GO:0048523 negative regulation of cellular process 58.8235 4 no
GO:0060255 regulation of macromolecule metabolic process 58.8235 4 no
GO:0080090 regulation of primary metabolic process 58.8235 4 no
GO:0051128 regulation of cellular component organization 52.9412 4 yes
GO:0099177 regulation of trans-synaptic signaling 47.0588 4 yes
GO:1902531 regulation of intracellular signal transduction 47.0588 5 no
GO:0050804 modulation of chemical synaptic transmission 47.0588 5 yes
GO:0009893 positive regulation of metabolic process 41.1765 4 no
GO:0019220 regulation of phosphate metabolic process 41.1765 6 no
GO:0031325 positive regulation of cellular metabolic process 41.1765 5 no
GO:0051049 regulation of transport 41.1765 4 no
GO:0051050 positive regulation of transport 41.1765 4 no
GO:0051174 regulation of phosphorus metabolic process 41.1765 5 no
GO:0051246 regulation of protein metabolic process 41.1765 5 no
GO:0006996 organelle organization 41.1765 4 yes
GO:0045595 regulation of cell differentiation 41.1765 4 yes
GO:0060284 regulation of cell development 35.2941 5 yes
GO:2000026 regulation of multicellular organismal development 35.2941 4 yes
GO:0001932 regulation of protein phosphorylation 35.2941 7 no
GO:0009892 negative regulation of metabolic process 35.2941 4 no
GO:0010604 positive regulation of macromolecule metabolic process 35.2941 5 no
GO:0010647 positive regulation of cell communication 35.2941 5 no
GO:0010959 regulation of metal ion transport 35.2941 6 no
GO:0023056 positive regulation of signaling 35.2941 4 no
GO:0031324 negative regulation of cellular metabolic process 35.2941 5 no
GO:0031399 regulation of protein modification process 35.2941 6 no
GO:0034762 regulation of transmembrane transport 35.2941 4 no
GO:0042325 regulation of phosphorylation 35.2941 7 no
GO:0043269 regulation of monoatomic ion transport 35.2941 5 no
GO:0043549 regulation of kinase activity 35.2941 5 no
GO:0045859 regulation of protein kinase activity 35.2941 6 no
GO:0051338 regulation of transferase activity 35.2941 4 no
GO:0051924 regulation of calcium ion transport 35.2941 7 no
GO:0071900 regulation of protein serine/threonine kinase activity 35.2941 7 no
GO:0141124 intracellular signaling cassette 35.2941 4 no
GO:0042981 regulation of apoptotic process 35.2941 5 no
GO:0043067 regulation of programmed cell death 35.2941 4 no
GO:0009889 regulation of biosynthetic process 35.2941 4 no
GO:0010468 regulation of gene expression 35.2941 6 no
GO:0010556 regulation of macromolecule biosynthetic process 35.2941 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 35.2941 5 no
GO:0031326 regulation of cellular biosynthetic process 35.2941 5 no
GO:0010563 negative regulation of phosphorus metabolic process 29.4118 6 no
GO:0010605 negative regulation of macromolecule metabolic process 29.4118 5 no
GO:0022898 regulation of transmembrane transporter activity 29.4118 4 no
GO:0034765 regulation of monoatomic ion transmembrane transport 29.4118 5 no
GO:0043270 positive regulation of monoatomic ion transport 29.4118 5 no
GO:0044057 regulation of system process 29.4118 4 no
GO:0045936 negative regulation of phosphate metabolic process 29.4118 7 no
GO:0048584 positive regulation of response to stimulus 29.4118 4 no
GO:0051726 regulation of cell cycle 29.4118 4 no
GO:0051928 positive regulation of calcium ion transport 29.4118 6 no
GO:1903169 regulation of calcium ion transmembrane transport 29.4118 7 no
GO:1904062 regulation of monoatomic cation transmembrane transport 29.4118 6 no
GO:0022607 cellular component assembly 29.4118 4 no
GO:0006355 regulation of DNA-templated transcription 29.4118 7 no
GO:0051252 regulation of RNA metabolic process 29.4118 5 no
GO:0060341 regulation of cellular localization 29.4118 4 no
GO:2001141 regulation of RNA biosynthetic process 29.4118 6 no
GO:0006796 phosphate-containing compound metabolic process 29.4118 4 yes
GO:0016310 phosphorylation 29.4118 5 yes
GO:0022603 regulation of anatomical structure morphogenesis 29.4118 4 yes
GO:0034330 cell junction organization 29.4118 4 yes
GO:0051094 positive regulation of developmental process 29.4118 4 yes
GO:0051240 positive regulation of multicellular organismal process 23.5294 4 yes
GO:0051592 response to calcium ion 23.5294 5 yes
GO:0051960 regulation of nervous system development 23.5294 5 yes
GO:0001933 negative regulation of protein phosphorylation 23.5294 8 no
GO:0001934 positive regulation of protein phosphorylation 23.5294 8 no
GO:0006937 regulation of muscle contraction 23.5294 6 no
GO:0006942 regulation of striated muscle contraction 23.5294 7 no
GO:0008016 regulation of heart contraction 23.5294 6 no
GO:0009967 positive regulation of signal transduction 23.5294 5 no
GO:0010562 positive regulation of phosphorus metabolic process 23.5294 6 no
GO:0010564 regulation of cell cycle process 23.5294 5 no
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 23.5294 6 no
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 23.5294 7 no
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 23.5294 6 no
GO:0019722 calcium-mediated signaling 23.5294 5 no
GO:0021762 substantia nigra development 23.5294 4 no
GO:0031400 negative regulation of protein modification process 23.5294 7 no
GO:0031401 positive regulation of protein modification process 23.5294 7 no
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 23.5294 5 no
GO:0033674 positive regulation of kinase activity 23.5294 6 no
GO:0034764 positive regulation of transmembrane transport 23.5294 5 no
GO:0034767 positive regulation of monoatomic ion transmembrane transport 23.5294 6 no
GO:0042326 negative regulation of phosphorylation 23.5294 8 no
GO:0042327 positive regulation of phosphorylation 23.5294 8 no
GO:0043085 positive regulation of catalytic activity 23.5294 4 no
GO:0044772 mitotic cell cycle phase transition 23.5294 4 no
GO:0045860 positive regulation of protein kinase activity 23.5294 7 no
GO:0045937 positive regulation of phosphate metabolic process 23.5294 7 no
GO:0051247 positive regulation of protein metabolic process 23.5294 6 no
GO:0051248 negative regulation of protein metabolic process 23.5294 6 no
GO:0051279 regulation of release of sequestered calcium ion into cytosol 23.5294 5 no
GO:0051282 regulation of sequestering of calcium ion 23.5294 4 no
GO:0051336 regulation of hydrolase activity 23.5294 4 no
GO:0051347 positive regulation of transferase activity 23.5294 5 no
GO:0055117 regulation of cardiac muscle contraction 23.5294 7 no
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 23.5294 6 no
GO:0071310 cellular response to organic substance 23.5294 4 no
GO:0071902 positive regulation of protein serine/threonine kinase activity 23.5294 8 no
GO:0090257 regulation of muscle system process 23.5294 5 no
GO:1901019 regulation of calcium ion transmembrane transporter activity 23.5294 6 no
GO:1903522 regulation of blood circulation 23.5294 5 no
GO:1904064 positive regulation of cation transmembrane transport 23.5294 7 no
GO:1904427 positive regulation of calcium ion transmembrane transport 23.5294 7 no
GO:2001257 regulation of cation channel activity 23.5294 6 no
GO:0048168 regulation of neuronal synaptic plasticity 23.5294 4 no
GO:0008104 protein localization 23.5294 4 no
GO:0009968 negative regulation of signal transduction 23.5294 5 no
GO:0010648 negative regulation of cell communication 23.5294 5 no
GO:0023057 negative regulation of signaling 23.5294 4 no
GO:0043066 negative regulation of apoptotic process 23.5294 6 no
GO:0043069 negative regulation of programmed cell death 23.5294 5 no
GO:0043408 regulation of MAPK cascade 23.5294 6 no
GO:0048585 negative regulation of response to stimulus 23.5294 4 no
GO:1902532 negative regulation of intracellular signal transduction 23.5294 6 no
GO:0006468 protein phosphorylation 23.5294 5 no
GO:0032880 regulation of protein localization 23.5294 5 no
GO:0036211 protein modification process 23.5294 4 no
GO:0043412 macromolecule modification 23.5294 4 no
GO:0009891 positive regulation of biosynthetic process 23.5294 5 no
GO:0031328 positive regulation of cellular biosynthetic process 23.5294 6 no
GO:0010038 response to metal ion 23.5294 4 yes
GO:0010720 positive regulation of cell development 23.5294 6 yes
GO:0030030 cell projection organization 23.5294 4 yes
GO:0045597 positive regulation of cell differentiation 23.5294 5 yes
GO:0050767 regulation of neurogenesis 23.5294 6 yes
GO:0050808 synapse organization 23.5294 5 yes
GO:0051130 positive regulation of cellular component organization 17.6471 5 yes
GO:0051962 positive regulation of nervous system development 17.6471 5 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 17.6471 6 yes
GO:0120036 plasma membrane bounded cell projection organization 17.6471 5 yes
GO:0007010 cytoskeleton organization 17.6471 5 yes
GO:0010975 regulation of neuron projection development 17.6471 7 yes
GO:0022604 regulation of cell morphogenesis 17.6471 5 yes
GO:0031344 regulation of cell projection organization 17.6471 5 yes
GO:0050769 positive regulation of neurogenesis 17.6471 6 yes
GO:0050807 regulation of synapse organization 17.6471 5 yes
GO:0060998 regulation of dendritic spine development 11.7647 4 yes
GO:0060999 positive regulation of dendritic spine development 11.7647 5 yes
GO:0061001 regulation of dendritic spine morphogenesis 11.7647 5 yes
GO:0061003 positive regulation of dendritic spine morphogenesis 11.7647 6 yes
GO:0099010 modification of postsynaptic structure 11.7647 7 yes
GO:0099175 regulation of postsynapse organization 11.7647 6 yes
GO:0099563 modification of synaptic structure 11.7647 6 yes
GO:0010770 positive regulation of cell morphogenesis 11.7647 6 yes
GO:0010976 positive regulation of neuron projection development 11.7647 7 yes
GO:0031346 positive regulation of cell projection organization 11.7647 6 yes
GO:0043954 cellular component maintenance 11.7647 4 yes
GO:0048814 regulation of dendrite morphogenesis 11.7647 5 yes
GO:0050773 regulation of dendrite development 11.7647 4 yes
GO:0050775 positive regulation of dendrite morphogenesis 11.7647 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CALM1_HUMAN [view entry] [view interactions] Low throughput yes yes
DREB_HUMAN [view entry] [view interactions] High throughput yes yes
NMDZ1_HUMAN [view entry] [view interactions] High throughput yes yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
ANS1B_HUMAN [view entry] [view interactions] High throughput yes yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
ITSN2_HUMAN [view entry] [view interactions] High throughput yes yes
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
GRIA4_HUMAN [view entry] [view interactions] High throughput yes no
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
ACTS_HUMAN [view interactions] High throughput no no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no