Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PSD3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Guanine nucleotide exchange factor for ARF6. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PSD3_HUMAN
GO:0043168 anion binding 42.8571 4 no
GO:0000166 nucleotide binding 38.0952 4 no
GO:0017076 purine nucleotide binding 38.0952 5 no
GO:0032555 purine ribonucleotide binding 38.0952 4 no
GO:0035639 purine ribonucleoside triphosphate binding 38.0952 4 no
GO:0016462 pyrophosphatase activity 33.3333 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 33.3333 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 33.3333 6 no
GO:0019900 kinase binding 30.9524 4 no
GO:0019901 protein kinase binding 30.9524 5 no
GO:0003924 GTPase activity 30.9524 7 no
GO:0005525 GTP binding 28.5714 5 no
GO:0019001 guanyl nucleotide binding 28.5714 6 no
GO:0032561 guanyl ribonucleotide binding 28.5714 5 no
GO:0030695 GTPase regulator activity 4.7619 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PSD3_HUMAN
GO:0048522 positive regulation of cellular process 69.0476 4 no
GO:0051128 regulation of cellular component organization 57.1429 4 no
GO:0010646 regulation of cell communication 52.3810 4 yes
GO:0048523 negative regulation of cellular process 50.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0008104 protein localization 50.0000 4 no
GO:0006996 organelle organization 45.2381 4 no
GO:0051049 regulation of transport 45.2381 4 no
GO:0080090 regulation of primary metabolic process 45.2381 4 no
GO:0009966 regulation of signal transduction 40.4762 4 yes
GO:0022607 cellular component assembly 40.4762 4 no
GO:0031323 regulation of cellular metabolic process 40.4762 4 no
GO:1902531 regulation of intracellular signal transduction 33.3333 5 yes
GO:0048584 positive regulation of response to stimulus 33.3333 4 no
GO:0071702 organic substance transport 33.3333 4 no
GO:0071705 nitrogen compound transport 33.3333 4 no
GO:0010647 positive regulation of cell communication 30.9524 5 no
GO:0023056 positive regulation of signaling 30.9524 4 no
GO:0031344 regulation of cell projection organization 30.9524 5 no
GO:0051246 regulation of protein metabolic process 30.9524 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 30.9524 6 no
GO:0044087 regulation of cellular component biogenesis 30.9524 4 no
GO:0009892 negative regulation of metabolic process 28.5714 4 no
GO:0009893 positive regulation of metabolic process 28.5714 4 no
GO:0010604 positive regulation of macromolecule metabolic process 28.5714 5 no
GO:0010605 negative regulation of macromolecule metabolic process 28.5714 5 no
GO:0030030 cell projection organization 28.5714 4 no
GO:0031324 negative regulation of cellular metabolic process 28.5714 5 no
GO:0141124 intracellular signaling cassette 28.5714 4 no
GO:0007010 cytoskeleton organization 28.5714 5 no
GO:0050804 modulation of chemical synaptic transmission 28.5714 5 no
GO:0099177 regulation of trans-synaptic signaling 28.5714 4 no
GO:0009889 regulation of biosynthetic process 26.1905 4 no
GO:0009967 positive regulation of signal transduction 26.1905 5 no
GO:0010468 regulation of gene expression 26.1905 6 no
GO:0010556 regulation of macromolecule biosynthetic process 26.1905 5 no
GO:0019220 regulation of phosphate metabolic process 26.1905 6 no
GO:0030334 regulation of cell migration 26.1905 5 no
GO:0031326 regulation of cellular biosynthetic process 26.1905 5 no
GO:0031399 regulation of protein modification process 26.1905 6 no
GO:0051174 regulation of phosphorus metabolic process 26.1905 5 no
GO:2000145 regulation of cell motility 26.1905 4 no
GO:0045595 regulation of cell differentiation 23.8095 4 no
GO:0051130 positive regulation of cellular component organization 23.8095 5 no
GO:0120036 plasma membrane bounded cell projection organization 23.8095 5 no
GO:2000026 regulation of multicellular organismal development 23.8095 4 no
GO:0007264 small GTPase-mediated signal transduction 23.8095 5 no
GO:0022603 regulation of anatomical structure morphogenesis 23.8095 4 no
GO:0060341 regulation of cellular localization 23.8095 4 no
GO:0015031 protein transport 23.8095 4 no
GO:0001932 regulation of protein phosphorylation 21.4286 7 no
GO:0010648 negative regulation of cell communication 21.4286 5 no
GO:0023057 negative regulation of signaling 21.4286 4 no
GO:0031175 neuron projection development 21.4286 6 no
GO:0032101 regulation of response to external stimulus 21.4286 4 no
GO:0042127 regulation of cell population proliferation 21.4286 4 no
GO:0042325 regulation of phosphorylation 21.4286 7 no
GO:0051094 positive regulation of developmental process 21.4286 4 no
GO:0051240 positive regulation of multicellular organismal process 21.4286 4 no
GO:0060627 regulation of vesicle-mediated transport 21.4286 4 no
GO:0033043 regulation of organelle organization 21.4286 5 no
GO:0032880 regulation of protein localization 21.4286 5 no
GO:0051050 positive regulation of transport 21.4286 4 no
GO:0050807 regulation of synapse organization 21.4286 5 no
GO:0051056 regulation of small GTPase mediated signal transduction 11.9048 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ARAP1_HUMAN [view interactions] Low throughput no yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC4_HUMAN [view interactions] High throughput no yes
DYR1A_HUMAN [view interactions] High throughput no yes
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
CTDSL_HUMAN [view interactions] High throughput no no
PTPRG_HUMAN [view interactions] High throughput no no
FGFR4_HUMAN [view interactions] High throughput no no
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
MX1_HUMAN [view interactions] High throughput no yes
MLH1_HUMAN [view interactions] High throughput no yes
PMS2_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
SMC1A_HUMAN [view interactions] High throughput no yes
SMC3_HUMAN [view entry] [view interactions] High throughput yes yes
STAG2_HUMAN [view interactions] High throughput no yes
WAPL_HUMAN [view interactions] High throughput no yes
EFMT3_HUMAN [view interactions] High throughput no no
NPAS1_HUMAN [view interactions] High throughput no no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOF_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
COPA_HUMAN [view entry] [view interactions] High throughput yes yes
COPB2_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
P53_HUMAN [view interactions] High throughput no no
PTPRA_HUMAN [view interactions] High throughput no yes
RASN_HUMAN [view entry] [view interactions] High throughput yes no
CNOT9_HUMAN [view interactions] High throughput no yes
DCP1A_HUMAN [view interactions] High throughput no yes
DNJC5_HUMAN [view interactions] High throughput no yes
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
CK052_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
CXAR_HUMAN [view interactions] High throughput no yes
DIRA3_HUMAN [view interactions] High throughput no yes
E41LA_HUMAN [view interactions] High throughput no yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
LAMP1_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP3_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
LYN_HUMAN [view entry] [view interactions] High throughput yes no
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
OCLN_HUMAN [view interactions] High throughput no no
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
ZFPL1_HUMAN [view interactions] High throughput no yes
ZYX_HUMAN [view interactions] High throughput no no
CDKL5_HUMAN [view entry] [view interactions] High throughput yes yes
CNTP2_HUMAN [view entry] [view interactions] High throughput yes yes
CBPZ_HUMAN [view interactions] High throughput no no
NMDE2_HUMAN [view entry] [view interactions] High throughput yes no
LRC4C_HUMAN [view entry] [view interactions] High throughput yes yes
NRX1A_HUMAN [view entry] [view interactions] High throughput yes no
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
PTK7_HUMAN [view interactions] High throughput no yes
SC6A1_HUMAN [view entry] [view interactions] High throughput yes no
SPAST_HUMAN [view interactions] High throughput no yes
STXB1_HUMAN [view entry] [view interactions] High throughput yes yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
MUC18_HUMAN [view interactions] High throughput no yes
SSR3_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no