CSKI1_HUMAN
May link the scaffolding protein CASK to downstream intracellular effectors. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI002568 | LIG_CaMK_CASK_1 | LIG | 374 | 379 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in CSKI1_HUMAN |
---|---|---|---|---|
GO:0046872 | metal ion binding | 30.4348 | 4 | no |
GO:0003779 | actin binding | 21.7391 | 4 | no |
GO:0005524 | ATP binding | 21.7391 | 5 | no |
GO:0017076 | purine nucleotide binding | 21.7391 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 21.7391 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 21.7391 | 4 | no |
GO:0032559 | adenyl ribonucleotide binding | 21.7391 | 5 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 21.7391 | 4 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in CSKI1_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 69.5652 | 4 | no |
GO:0010646 | regulation of cell communication | 65.2174 | 4 | no |
GO:0050804 | modulation of chemical synaptic transmission | 52.1739 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 52.1739 | 4 | no |
GO:0051128 | regulation of cellular component organization | 47.8261 | 4 | no |
GO:0009966 | regulation of signal transduction | 47.8261 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 43.4783 | 4 | no |
GO:0022607 | cellular component assembly | 39.1304 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 39.1304 | 5 | no |
GO:0010468 | regulation of gene expression | 39.1304 | 5 | no |
GO:0048523 | negative regulation of cellular process | 39.1304 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 39.1304 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 39.1304 | 4 | no |
GO:0010647 | positive regulation of cell communication | 39.1304 | 5 | no |
GO:0023056 | positive regulation of signaling | 39.1304 | 4 | no |
GO:0051049 | regulation of transport | 39.1304 | 4 | no |
GO:0006996 | organelle organization | 34.7826 | 4 | no |
GO:0033043 | regulation of organelle organization | 34.7826 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 34.7826 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 34.7826 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 34.7826 | 5 | no |
GO:0031323 | regulation of cellular metabolic process | 34.7826 | 4 | no |
GO:0043269 | regulation of ion transport | 34.7826 | 5 | no |
GO:0034330 | cell junction organization | 30.4348 | 4 | no |
GO:0051493 | regulation of cytoskeleton organization | 30.4348 | 6 | no |
GO:0050890 | cognition | 30.4348 | 4 | no |
GO:0051094 | positive regulation of developmental process | 30.4348 | 4 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 30.4348 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 30.4348 | 5 | no |
GO:0080134 | regulation of response to stress | 30.4348 | 4 | no |
GO:0007268 | chemical synaptic transmission | 30.4348 | 6 | no |
GO:0098916 | anterograde trans-synaptic signaling | 30.4348 | 5 | no |
GO:0099537 | trans-synaptic signaling | 30.4348 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 30.4348 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 30.4348 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 30.4348 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 30.4348 | 5 | no |
GO:0050806 | positive regulation of synaptic transmission | 30.4348 | 5 | no |
GO:0048584 | positive regulation of response to stimulus | 30.4348 | 4 | no |
GO:0051050 | positive regulation of transport | 30.4348 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 26.0870 | 6 | no |
GO:0031325 | positive regulation of cellular metabolic process | 26.0870 | 5 | no |
GO:0031399 | regulation of protein modification process | 26.0870 | 6 | no |
GO:0042325 | regulation of phosphorylation | 26.0870 | 7 | no |
GO:0045595 | regulation of cell differentiation | 26.0870 | 4 | no |
GO:0050808 | synapse organization | 26.0870 | 5 | no |
GO:0051174 | regulation of phosphorus metabolic process | 26.0870 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 26.0870 | 6 | no |
GO:0051336 | regulation of hydrolase activity | 26.0870 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 26.0870 | 5 | no |
GO:0008104 | protein localization | 26.0870 | 4 | no |
GO:0043270 | positive regulation of ion transport | 26.0870 | 5 | no |
GO:0006836 | neurotransmitter transport | 26.0870 | 4 | no |
GO:0051046 | regulation of secretion | 26.0870 | 5 | no |
GO:1903530 | regulation of secretion by cell | 26.0870 | 4 | no |
GO:0006796 | phosphate-containing compound metabolic process | 21.7391 | 4 | no |
GO:0010638 | positive regulation of organelle organization | 21.7391 | 6 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 21.7391 | 4 | no |
GO:0031344 | regulation of cell projection organization | 21.7391 | 5 | no |
GO:0034329 | cell junction assembly | 21.7391 | 5 | no |
GO:0036211 | protein modification process | 21.7391 | 4 | no |
GO:0043412 | macromolecule modification | 21.7391 | 4 | no |
GO:0044089 | positive regulation of cellular component biogenesis | 21.7391 | 5 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 21.7391 | 6 | no |
GO:1902903 | regulation of supramolecular fiber organization | 21.7391 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 21.7391 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 21.7391 | 5 | no |
GO:0030030 | cell projection organization | 21.7391 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 21.7391 | 5 | no |
GO:0043085 | positive regulation of catalytic activity | 21.7391 | 4 | no |
GO:0043086 | negative regulation of catalytic activity | 21.7391 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 21.7391 | 5 | no |
GO:0051240 | positive regulation of multicellular organismal process | 21.7391 | 4 | no |
GO:0051248 | negative regulation of protein metabolic process | 21.7391 | 6 | no |
GO:0051338 | regulation of transferase activity | 21.7391 | 4 | no |
GO:0051960 | regulation of nervous system development | 21.7391 | 5 | no |
GO:0051962 | positive regulation of nervous system development | 21.7391 | 5 | no |
GO:0080135 | regulation of cellular response to stress | 21.7391 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 21.7391 | 5 | no |
GO:2000026 | regulation of multicellular organismal development | 21.7391 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 21.7391 | 7 | no |
GO:0006355 | regulation of DNA-templated transcription | 21.7391 | 6 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 21.7391 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 21.7391 | 6 | no |
GO:0016192 | vesicle-mediated transport | 21.7391 | 4 | no |
GO:0023061 | signal release | 21.7391 | 4 | no |
GO:0046903 | secretion | 21.7391 | 4 | no |
GO:0046928 | regulation of neurotransmitter secretion | 21.7391 | 4 | no |
GO:0051588 | regulation of neurotransmitter transport | 21.7391 | 5 | no |
GO:0060627 | regulation of vesicle-mediated transport | 21.7391 | 4 | no |
GO:0099643 | signal release from synapse | 21.7391 | 5 | no |
GO:0009891 | positive regulation of biosynthetic process | 21.7391 | 5 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 21.7391 | 6 | no |
GO:0071702 | organic substance transport | 21.7391 | 4 | no |
GO:0071705 | nitrogen compound transport | 21.7391 | 4 | no |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
ABI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSKP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSKI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CASK_HUMAN | [view interactions] | High throughput | no | no |
EPHA2_HUMAN | [view interactions] | High throughput | no | no |
L1CAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCK1_HUMAN | [view interactions] | High throughput | no | yes |
MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
STMN3_HUMAN | [view interactions] | High throughput | no | yes |
NRX2A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SIAH1_HUMAN | [view interactions] | High throughput | no | yes |
SEPT4_HUMAN | [view interactions] | High throughput | no | no |
HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PEX5R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYOME_HUMAN | [view interactions] | High throughput | no | no |
DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTN2_HUMAN | [view interactions] | High throughput | no | yes |
RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AKT3_HUMAN | [view interactions] | High throughput | no | yes |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NRX1A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GP153_HUMAN | [view interactions] | Computational | no | yes |