ABLM2_HUMAN
Evidence for PS localization
Functions
May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABLM2_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 50.0000 | 4 | yes |
| GO:0003779 | actin binding | 41.6667 | 4 | yes |
| GO:0046872 | metal ion binding | 33.3333 | 5 | yes |
| GO:0019900 | kinase binding | 33.3333 | 4 | no |
| GO:0019901 | protein kinase binding | 33.3333 | 5 | no |
| GO:0045296 | cadherin binding | 25.0000 | 4 | no |
| GO:0005216 | monoatomic ion channel activity | 25.0000 | 4 | no |
| GO:0005244 | voltage-gated monoatomic ion channel activity | 25.0000 | 5 | no |
| GO:0015267 | channel activity | 25.0000 | 4 | no |
| GO:0022832 | voltage-gated channel activity | 25.0000 | 6 | no |
| GO:0022836 | gated channel activity | 25.0000 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABLM2_HUMAN |
|---|---|---|---|---|
| GO:0006996 | organelle organization | 58.3333 | 4 | yes |
| GO:0007010 | cytoskeleton organization | 50.0000 | 5 | yes |
| GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 41.6667 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 41.6667 | 4 | no |
| GO:0006811 | monoatomic ion transport | 33.3333 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 33.3333 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 33.3333 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 33.3333 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 33.3333 | 4 | no |
| GO:0008104 | protein localization | 25.0000 | 4 | no |
| GO:0046903 | secretion | 25.0000 | 4 | no |
| GO:0043933 | protein-containing complex organization | 25.0000 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 25.0000 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 25.0000 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 25.0000 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 25.0000 | 5 | no |
| GO:0080090 | regulation of primary metabolic process | 25.0000 | 4 | no |
| GO:0030030 | cell projection organization | 16.6667 | 4 | yes |
| GO:0030031 | cell projection assembly | 16.6667 | 5 | yes |
| GO:0030032 | lamellipodium assembly | 16.6667 | 7 | yes |
| GO:0097581 | lamellipodium organization | 16.6667 | 6 | yes |
| GO:0120031 | plasma membrane bounded cell projection assembly | 16.6667 | 6 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 16.6667 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ABRA_HUMAN | [view interactions] | Low throughput | no | no |
| ACTS_HUMAN | [view interactions] | Low throughput | no | no |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| SRBP2_HUMAN | [view interactions] | High throughput | no | yes |
| TITIN_HUMAN | [view interactions] | High throughput | no | no |
| MLIP_HUMAN | [view interactions] | High throughput | no | yes |
| VPP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHNK2_HUMAN | [view interactions] | High throughput | no | yes |
| LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| TRPV1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASXL2_HUMAN | [view interactions] | High throughput | no | no |
| KDM1B_HUMAN | [view interactions] | High throughput | no | yes |
| AFAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHL1_HUMAN | [view interactions] | High throughput | no | no |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLEC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |