Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ABLM2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ABLM2_HUMAN
GO:0003779 actin binding 36.3636 4 yes
GO:0046872 metal ion binding 36.3636 4 yes
GO:0019900 kinase binding 36.3636 4 no
GO:0019901 protein kinase binding 36.3636 5 no
GO:0005216 ion channel activity 27.2727 4 no
GO:0005244 voltage-gated ion channel activity 27.2727 4 no
GO:0015267 channel activity 27.2727 4 no
GO:0022832 voltage-gated channel activity 27.2727 6 no
GO:0022836 gated channel activity 27.2727 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in ABLM2_HUMAN
GO:0006996 organelle organization 54.5455 4 yes
GO:0031323 regulation of cellular metabolic process 54.5455 4 no
GO:0048523 negative regulation of cellular process 54.5455 4 no
GO:0007010 cytoskeleton organization 45.4545 5 yes
GO:0022607 cellular component assembly 36.3636 4 yes
GO:0009892 negative regulation of metabolic process 36.3636 4 no
GO:0010605 negative regulation of macromolecule metabolic process 36.3636 5 no
GO:0031324 negative regulation of cellular metabolic process 36.3636 5 no
GO:0048522 positive regulation of cellular process 36.3636 4 no
GO:0051128 regulation of cellular component organization 36.3636 4 no
GO:0051171 regulation of nitrogen compound metabolic process 36.3636 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 36.3636 5 no
GO:0060255 regulation of macromolecule metabolic process 36.3636 4 no
GO:0080090 regulation of primary metabolic process 36.3636 4 no
GO:0046903 secretion 27.2727 4 no
GO:0001932 regulation of protein phosphorylation 27.2727 7 no
GO:0001933 negative regulation of protein phosphorylation 27.2727 8 no
GO:0006469 negative regulation of protein kinase activity 27.2727 7 no
GO:0009893 positive regulation of metabolic process 27.2727 4 no
GO:0010563 negative regulation of phosphorus metabolic process 27.2727 6 no
GO:0019220 regulation of phosphate metabolic process 27.2727 6 no
GO:0031325 positive regulation of cellular metabolic process 27.2727 5 no
GO:0031399 regulation of protein modification process 27.2727 6 no
GO:0031400 negative regulation of protein modification process 27.2727 7 no
GO:0033673 negative regulation of kinase activity 27.2727 6 no
GO:0042325 regulation of phosphorylation 27.2727 7 no
GO:0042326 negative regulation of phosphorylation 27.2727 8 no
GO:0043086 negative regulation of catalytic activity 27.2727 4 no
GO:0043549 regulation of kinase activity 27.2727 5 no
GO:0045859 regulation of protein kinase activity 27.2727 6 no
GO:0045936 negative regulation of phosphate metabolic process 27.2727 7 no
GO:0051049 regulation of transport 27.2727 4 no
GO:0051174 regulation of phosphorus metabolic process 27.2727 5 no
GO:0051246 regulation of protein metabolic process 27.2727 5 no
GO:0051248 negative regulation of protein metabolic process 27.2727 6 no
GO:0051338 regulation of transferase activity 27.2727 4 no
GO:0051348 negative regulation of transferase activity 27.2727 5 no
GO:0006811 ion transport 27.2727 4 no
GO:0006820 anion transport 27.2727 5 no
GO:0010941 regulation of cell death 27.2727 4 no
GO:0042981 regulation of apoptotic process 27.2727 6 no
GO:0043067 regulation of programmed cell death 27.2727 5 no
GO:0030030 cell projection organization 18.1818 4 yes
GO:0030031 cell projection assembly 18.1818 5 yes
GO:0030032 lamellipodium assembly 18.1818 7 yes
GO:0097581 lamellipodium organization 18.1818 6 yes
GO:0120031 plasma membrane bounded cell projection assembly 18.1818 6 yes
GO:0120036 plasma membrane bounded cell projection organization 18.1818 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ABRA_HUMAN [view interactions] Low throughput no no
ACTS_HUMAN [view interactions] Low throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
SRBP2_HUMAN [view interactions] High throughput no yes
TITIN_HUMAN [view interactions] High throughput no no
MLIP_HUMAN [view interactions] High throughput no yes
VPP1_HUMAN [view entry] [view interactions] High throughput yes yes
AHNK2_HUMAN [view interactions] High throughput no yes
LIN7C_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPL_HUMAN [view interactions] High throughput no yes
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
ASXL2_HUMAN [view interactions] High throughput no no
KDM1B_HUMAN [view interactions] High throughput no yes
AFAD_HUMAN [view interactions] High throughput no yes
ABLM1_HUMAN [view entry] [view interactions] High throughput yes yes
FHL1_HUMAN [view interactions] High throughput no no
SYNE2_HUMAN [view interactions] High throughput no no
VDAC1_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC2_HUMAN [view entry] [view interactions] High throughput yes yes
ZYX_HUMAN [view interactions] High throughput no no
PDLI5_HUMAN [view entry] [view interactions] High throughput yes no
PLEC_HUMAN [view entry] [view interactions] High throughput yes yes