ANXA3_HUMAN
Evidence for PS localization
Functions
Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ANXA3_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 37.5000 | 4 | yes |
| GO:0005509 | calcium ion binding | 25.0000 | 5 | yes |
| GO:0005544 | calcium-dependent phospholipid binding | 25.0000 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ANXA3_HUMAN |
|---|---|---|---|---|
| GO:0016192 | vesicle-mediated transport | 50.0000 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 50.0000 | 4 | yes |
| GO:0006887 | exocytosis | 37.5000 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 37.5000 | 4 | yes |
| GO:0010468 | regulation of gene expression | 37.5000 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 37.5000 | 5 | yes |
| GO:0030334 | regulation of cell migration | 37.5000 | 5 | yes |
| GO:0046903 | secretion | 37.5000 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 37.5000 | 4 | yes |
| GO:2000145 | regulation of cell motility | 37.5000 | 4 | yes |
| GO:0006996 | organelle organization | 37.5000 | 4 | no |
| GO:0008104 | protein localization | 37.5000 | 4 | no |
| GO:0010941 | regulation of cell death | 37.5000 | 4 | no |
| GO:0015031 | protein transport | 37.5000 | 4 | no |
| GO:0022607 | cellular component assembly | 37.5000 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 37.5000 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 37.5000 | 5 | no |
| GO:0061024 | membrane organization | 37.5000 | 4 | no |
| GO:0071702 | organic substance transport | 37.5000 | 4 | no |
| GO:0071705 | nitrogen compound transport | 37.5000 | 4 | no |
| GO:0006909 | phagocytosis | 25.0000 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.0000 | 5 | yes |
| GO:0030335 | positive regulation of cell migration | 25.0000 | 6 | yes |
| GO:0031323 | regulation of cellular metabolic process | 25.0000 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 25.0000 | 5 | yes |
| GO:0040017 | positive regulation of locomotion | 25.0000 | 4 | yes |
| GO:0051052 | regulation of DNA metabolic process | 25.0000 | 5 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 25.0000 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 25.0000 | 5 | yes |
| GO:0080090 | regulation of primary metabolic process | 25.0000 | 4 | yes |
| GO:2000147 | positive regulation of cell motility | 25.0000 | 5 | yes |
| GO:0006886 | intracellular protein transport | 25.0000 | 4 | no |
| GO:0006906 | vesicle fusion | 25.0000 | 6 | no |
| GO:0009966 | regulation of signal transduction | 25.0000 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 25.0000 | 6 | no |
| GO:0010646 | regulation of cell communication | 25.0000 | 4 | no |
| GO:0016050 | vesicle organization | 25.0000 | 5 | no |
| GO:0031629 | synaptic vesicle fusion to presynaptic active zone membrane | 25.0000 | 4 | no |
| GO:0032880 | regulation of protein localization | 25.0000 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 25.0000 | 4 | no |
| GO:0043933 | protein-containing complex organization | 25.0000 | 4 | no |
| GO:0048284 | organelle fusion | 25.0000 | 5 | no |
| GO:0048499 | synaptic vesicle membrane organization | 25.0000 | 5 | no |
| GO:0051049 | regulation of transport | 25.0000 | 4 | no |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | no |
| GO:0061025 | membrane fusion | 25.0000 | 5 | no |
| GO:0065003 | protein-containing complex assembly | 25.0000 | 5 | no |
| GO:0090174 | organelle membrane fusion | 25.0000 | 6 | no |
| GO:2001233 | regulation of apoptotic signaling pathway | 25.0000 | 5 | no |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 25.0000 | 6 | no |
| GO:0010038 | response to metal ion | 25.0000 | 4 | no |
| GO:0051592 | response to calcium ion | 25.0000 | 5 | no |
| GO:0034330 | cell junction organization | 25.0000 | 4 | no |
| GO:0006811 | ion transport | 25.0000 | 4 | no |
| GO:0006812 | cation transport | 25.0000 | 5 | no |
| GO:0036293 | response to decreased oxygen levels | 25.0000 | 4 | no |
| GO:0044057 | regulation of system process | 25.0000 | 4 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 25.0000 | 4 | no |
| GO:0090257 | regulation of muscle system process | 25.0000 | 5 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| SH2D3_HUMAN | [view interactions] | High throughput | no | no |
| RA51D_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| RASA1_HUMAN | [view interactions] | High throughput | no | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| ITB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| UBR1_HUMAN | [view interactions] | High throughput | no | yes |
| U119A_HUMAN | [view interactions] | High throughput | no | no |
| IGS21_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEP1_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| EYA1_HUMAN | [view interactions] | High throughput | no | no |
| FBLN3_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CDC27_HUMAN | [view interactions] | High throughput | no | yes |
| SIA7F_HUMAN | [view interactions] | High throughput | no | yes |
| GABPA_HUMAN | [view interactions] | High throughput | no | no |
| ELOA2_HUMAN | [view interactions] | High throughput | no | yes |
| KLH11_HUMAN | [view interactions] | High throughput | no | yes |
| GBG8_HUMAN | [view interactions] | High throughput | no | no |
| FA24B_HUMAN | [view interactions] | High throughput | no | no |
| PATE2_HUMAN | [view interactions] | High throughput | no | no |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| ST7_HUMAN | [view interactions] | High throughput | no | yes |
| STX17_HUMAN | [view interactions] | High throughput | no | yes |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANX11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STXB2_HUMAN | [view interactions] | High throughput | no | no |
| ANXA4_HUMAN | [view interactions] | High throughput | no | no |
| SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPA_HUMAN | [view interactions] | High throughput | no | yes |
| SSNA1_HUMAN | [view interactions] | High throughput | no | no |