ANXA3_HUMAN
Evidence for PS localization
Functions
Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ANXA3_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 41.6667 | 4 | yes |
| GO:0046872 | metal ion binding | 41.6667 | 5 | yes |
| GO:0005509 | calcium ion binding | 16.6667 | 6 | yes |
| GO:0005544 | calcium-dependent phospholipid binding | 16.6667 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ANXA3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 50.0000 | 4 | yes |
| GO:0006996 | organelle organization | 50.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 41.6667 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 41.6667 | 5 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 41.6667 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 41.6667 | 4 | no |
| GO:0010646 | regulation of cell communication | 41.6667 | 4 | no |
| GO:0022607 | cellular component assembly | 41.6667 | 4 | no |
| GO:0043933 | protein-containing complex organization | 41.6667 | 4 | no |
| GO:0008104 | protein localization | 41.6667 | 4 | no |
| GO:0071702 | organic substance transport | 41.6667 | 4 | no |
| GO:0071705 | nitrogen compound transport | 41.6667 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 33.3333 | 4 | yes |
| GO:0010468 | regulation of gene expression | 33.3333 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 33.3333 | 5 | yes |
| GO:0031323 | regulation of cellular metabolic process | 33.3333 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 33.3333 | 5 | yes |
| GO:0080090 | regulation of primary metabolic process | 33.3333 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 33.3333 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 33.3333 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 33.3333 | 4 | no |
| GO:0061024 | membrane organization | 33.3333 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.0000 | 5 | yes |
| GO:0030334 | regulation of cell migration | 25.0000 | 5 | yes |
| GO:0046903 | secretion | 25.0000 | 4 | yes |
| GO:0098657 | import into cell | 25.0000 | 4 | yes |
| GO:2000145 | regulation of cell motility | 25.0000 | 4 | yes |
| GO:0009968 | negative regulation of signal transduction | 25.0000 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 25.0000 | 5 | no |
| GO:0023057 | negative regulation of signaling | 25.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 25.0000 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 25.0000 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 25.0000 | 5 | no |
| GO:0010038 | response to metal ion | 25.0000 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 25.0000 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 25.0000 | 7 | no |
| GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 25.0000 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 25.0000 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 25.0000 | 6 | no |
| GO:0032880 | regulation of protein localization | 25.0000 | 5 | no |
| GO:0033365 | protein localization to organelle | 25.0000 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 25.0000 | 4 | no |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | no |
| GO:0071310 | cellular response to organic substance | 25.0000 | 4 | no |
| GO:2001233 | regulation of apoptotic signaling pathway | 25.0000 | 5 | no |
| GO:0015031 | protein transport | 25.0000 | 4 | no |
| GO:0016050 | vesicle organization | 25.0000 | 5 | no |
| GO:0061025 | membrane fusion | 25.0000 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 16.6667 | 7 | yes |
| GO:0006909 | phagocytosis | 16.6667 | 4 | yes |
| GO:0014070 | response to organic cyclic compound | 16.6667 | 4 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 16.6667 | 4 | yes |
| GO:0030335 | positive regulation of cell migration | 16.6667 | 6 | yes |
| GO:0040017 | positive regulation of locomotion | 16.6667 | 4 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 16.6667 | 5 | yes |
| GO:0051052 | regulation of DNA metabolic process | 16.6667 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 16.6667 | 4 | yes |
| GO:0051252 | regulation of RNA metabolic process | 16.6667 | 5 | yes |
| GO:2000147 | positive regulation of cell motility | 16.6667 | 5 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 16.6667 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| GABPA_HUMAN | [view interactions] | High throughput | no | no |
| ELOA2_HUMAN | [view interactions] | High throughput | no | yes |
| KLH11_HUMAN | [view interactions] | High throughput | no | yes |
| GBG8_HUMAN | [view interactions] | High throughput | no | no |
| FA24B_HUMAN | [view interactions] | High throughput | no | no |
| PATE2_HUMAN | [view interactions] | High throughput | no | no |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| ST7_HUMAN | [view interactions] | High throughput | no | yes |
| STX17_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYTN_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| ITB7_HUMAN | [view interactions] | High throughput | no | no |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANX11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STXB2_HUMAN | [view interactions] | High throughput | no | no |
| ANXA4_HUMAN | [view interactions] | High throughput | no | no |
| SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPA_HUMAN | [view interactions] | High throughput | no | yes |
| SSNA1_HUMAN | [view interactions] | High throughput | no | no |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRNT1_HUMAN | [view interactions] | High throughput | no | yes |
| TACO1_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUP43_HUMAN | [view interactions] | High throughput | no | yes |
| NUP35_HUMAN | [view interactions] | High throughput | no | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| SH2D3_HUMAN | [view interactions] | High throughput | no | no |
| RA51D_HUMAN | [view interactions] | High throughput | no | no |
| CDN2A_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| RASA1_HUMAN | [view interactions] | High throughput | no | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| ITB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| UBR1_HUMAN | [view interactions] | High throughput | no | yes |
| U119A_HUMAN | [view interactions] | High throughput | no | no |
| IGS21_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEP1_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| EYA1_HUMAN | [view interactions] | High throughput | no | no |
| FBLN3_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CDC27_HUMAN | [view interactions] | High throughput | no | yes |
| SIA7F_HUMAN | [view interactions] | High throughput | no | yes |