IGS21_HUMAN
Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in IGS21_HUMAN |
---|---|---|---|---|
GO:0019900 | kinase binding | 25.0000 | 4 | no |
GO:0019901 | protein kinase binding | 25.0000 | 5 | no |
GO:0017076 | purine nucleotide binding | 25.0000 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 25.0000 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 25.0000 | 4 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in IGS21_HUMAN |
---|---|---|---|---|
GO:0031323 | regulation of cellular metabolic process | 66.6667 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 66.6667 | 4 | no |
GO:0048522 | positive regulation of cellular process | 58.3333 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 58.3333 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 50.0000 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 50.0000 | 5 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 50.0000 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 41.6667 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 41.6667 | 5 | no |
GO:0031399 | regulation of protein modification process | 41.6667 | 6 | no |
GO:0048523 | negative regulation of cellular process | 41.6667 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 41.6667 | 5 | no |
GO:0009966 | regulation of signal transduction | 41.6667 | 4 | no |
GO:0010646 | regulation of cell communication | 41.6667 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 33.3333 | 4 | no |
GO:0010468 | regulation of gene expression | 33.3333 | 5 | no |
GO:0030334 | regulation of cell migration | 33.3333 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 33.3333 | 5 | no |
GO:2000145 | regulation of cell motility | 33.3333 | 4 | no |
GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 33.3333 | 6 | no |
GO:0031324 | negative regulation of cellular metabolic process | 33.3333 | 5 | no |
GO:0051049 | regulation of transport | 33.3333 | 4 | no |
GO:0051174 | regulation of phosphorus metabolic process | 33.3333 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 33.3333 | 6 | no |
GO:0008104 | protein localization | 33.3333 | 4 | no |
GO:0080134 | regulation of response to stress | 33.3333 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 33.3333 | 5 | no |
GO:0006996 | organelle organization | 33.3333 | 4 | no |
GO:0050804 | modulation of chemical synaptic transmission | 33.3333 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 33.3333 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 25.0000 | 5 | no |
GO:0016192 | vesicle-mediated transport | 25.0000 | 4 | no |
GO:0033993 | response to lipid | 25.0000 | 4 | no |
GO:0051094 | positive regulation of developmental process | 25.0000 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 25.0000 | 7 | no |
GO:0010563 | negative regulation of phosphorus metabolic process | 25.0000 | 6 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 25.0000 | 5 | no |
GO:0031400 | negative regulation of protein modification process | 25.0000 | 7 | no |
GO:0031401 | positive regulation of protein modification process | 25.0000 | 7 | no |
GO:0042325 | regulation of phosphorylation | 25.0000 | 7 | no |
GO:0043085 | positive regulation of catalytic activity | 25.0000 | 4 | no |
GO:0043086 | negative regulation of catalytic activity | 25.0000 | 4 | no |
GO:0045936 | negative regulation of phosphate metabolic process | 25.0000 | 7 | no |
GO:0051046 | regulation of secretion | 25.0000 | 5 | no |
GO:0051128 | regulation of cellular component organization | 25.0000 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 25.0000 | 5 | no |
GO:0051248 | negative regulation of protein metabolic process | 25.0000 | 6 | no |
GO:0051338 | regulation of transferase activity | 25.0000 | 4 | no |
GO:0051348 | negative regulation of transferase activity | 25.0000 | 5 | no |
GO:1903530 | regulation of secretion by cell | 25.0000 | 4 | no |
GO:0022607 | cellular component assembly | 25.0000 | 4 | no |
GO:0006886 | intracellular protein transport | 25.0000 | 4 | no |
GO:0010628 | positive regulation of gene expression | 25.0000 | 6 | no |
GO:0010941 | regulation of cell death | 25.0000 | 4 | no |
GO:0015031 | protein transport | 25.0000 | 4 | no |
GO:0042981 | regulation of apoptotic process | 25.0000 | 6 | no |
GO:0043066 | negative regulation of apoptotic process | 25.0000 | 7 | no |
GO:0043067 | regulation of programmed cell death | 25.0000 | 5 | no |
GO:0043069 | negative regulation of programmed cell death | 25.0000 | 6 | no |
GO:0048584 | positive regulation of response to stimulus | 25.0000 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | no |
GO:0060548 | negative regulation of cell death | 25.0000 | 5 | no |
GO:0071310 | cellular response to organic substance | 25.0000 | 4 | no |
GO:0071702 | organic substance transport | 25.0000 | 4 | no |
GO:0071705 | nitrogen compound transport | 25.0000 | 4 | no |
GO:0080135 | regulation of cellular response to stress | 25.0000 | 4 | no |
GO:0036211 | protein modification process | 25.0000 | 4 | no |
GO:0043412 | macromolecule modification | 25.0000 | 4 | no |
GO:0051093 | negative regulation of developmental process | 25.0000 | 4 | no |
GO:0007010 | cytoskeleton organization | 25.0000 | 5 | no |
GO:0034330 | cell junction organization | 25.0000 | 4 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
GA45A_HUMAN | [view interactions] | High throughput | no | no |
GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PPT1_HUMAN | [view interactions] | High throughput | no | yes |
GIPC2_HUMAN | [view interactions] | High throughput | no | yes |
SPB9_HUMAN | [view interactions] | High throughput | no | no |
UB2V2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ALDH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ANXA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ATF3_HUMAN | [view interactions] | High throughput | no | yes |
BCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BTBD2_HUMAN | [view interactions] | High throughput | no | no |
ERH_HUMAN | [view interactions] | High throughput | no | yes |
GSTM4_HUMAN | [view interactions] | High throughput | no | yes |
ANM1_HUMAN | [view interactions] | High throughput | no | yes |
HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MD2BP_HUMAN | [view interactions] | High throughput | no | no |
CRCT1_HUMAN | [view interactions] | High throughput | no | no |
PAEP_HUMAN | [view interactions] | High throughput | no | no |
PA1B3_HUMAN | [view interactions] | High throughput | no | no |
PCDA4_HUMAN | [view interactions] | High throughput | no | yes |
PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S10A8_HUMAN | [view interactions] | High throughput | no | no |
SPS1_HUMAN | [view interactions] | High throughput | no | yes |
ST1E1_HUMAN | [view interactions] | High throughput | no | no |
TYB4_HUMAN | [view interactions] | High throughput | no | yes |
NREP_HUMAN | [view interactions] | High throughput | no | yes |
DGKD_HUMAN | [view interactions] | High throughput | no | yes |
ETHE1_HUMAN | [view interactions] | High throughput | no | yes |
RPP14_HUMAN | [view interactions] | High throughput | no | no |
E41L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NACAM_HUMAN | [view interactions] | High throughput | no | no |
RBPS2_HUMAN | [view interactions] | High throughput | no | no |
GRAK_HUMAN | [view interactions] | High throughput | no | no |
TBB1_HUMAN | [view interactions] | High throughput | no | yes |
HXD13_HUMAN | [view interactions] | High throughput | no | no |
CCG8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CBWD3_HUMAN | [view interactions] | High throughput | no | yes |
MIER3_HUMAN | [view interactions] | High throughput | no | yes |