Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PHLB1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PHLB1_HUMAN
GO:0003723 RNA binding 38.0952 4 no
GO:0042803 protein homodimerization activity 23.8095 4 no
GO:0017076 purine nucleotide binding 23.8095 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in PHLB1_HUMAN
GO:0048522 positive regulation of cellular process 76.1905 4 yes
GO:0031323 regulation of cellular metabolic process 71.4286 4 no
GO:0051171 regulation of nitrogen compound metabolic process 66.6667 4 no
GO:0060255 regulation of macromolecule metabolic process 66.6667 4 no
GO:0080090 regulation of primary metabolic process 66.6667 4 no
GO:0048523 negative regulation of cellular process 57.1429 4 no
GO:0010468 regulation of gene expression 52.3810 5 no
GO:0051128 regulation of cellular component organization 47.6190 4 yes
GO:0009893 positive regulation of metabolic process 47.6190 4 no
GO:0009889 regulation of biosynthetic process 42.8571 4 no
GO:0010556 regulation of macromolecule biosynthetic process 42.8571 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 42.8571 5 no
GO:0031326 regulation of cellular biosynthetic process 42.8571 5 no
GO:0051252 regulation of RNA metabolic process 42.8571 5 no
GO:0009892 negative regulation of metabolic process 42.8571 4 no
GO:0010605 negative regulation of macromolecule metabolic process 42.8571 5 no
GO:0031325 positive regulation of cellular metabolic process 42.8571 5 no
GO:0031324 negative regulation of cellular metabolic process 38.0952 5 no
GO:0051172 negative regulation of nitrogen compound metabolic process 38.0952 5 no
GO:0051246 regulation of protein metabolic process 38.0952 5 no
GO:0009894 regulation of catabolic process 33.3333 4 no
GO:0019220 regulation of phosphate metabolic process 33.3333 6 no
GO:0031329 regulation of cellular catabolic process 33.3333 5 no
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0051174 regulation of phosphorus metabolic process 33.3333 5 no
GO:0009966 regulation of signal transduction 33.3333 4 no
GO:0010646 regulation of cell communication 33.3333 4 no
GO:0006996 organelle organization 33.3333 4 no
GO:0033043 regulation of organelle organization 28.5714 5 yes
GO:0044087 regulation of cellular component biogenesis 28.5714 4 yes
GO:0006355 regulation of DNA-templated transcription 28.5714 6 no
GO:1903506 regulation of nucleic acid-templated transcription 28.5714 7 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0009890 negative regulation of biosynthetic process 28.5714 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 28.5714 6 no
GO:0010604 positive regulation of macromolecule metabolic process 28.5714 5 no
GO:0031327 negative regulation of cellular biosynthetic process 28.5714 6 no
GO:0031344 regulation of cell projection organization 28.5714 5 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 28.5714 6 no
GO:0008104 protein localization 28.5714 4 no
GO:0042127 regulation of cell population proliferation 28.5714 4 no
GO:0051049 regulation of transport 28.5714 4 no
GO:0051726 regulation of cell cycle 28.5714 4 no
GO:0071702 organic substance transport 28.5714 4 no
GO:0071705 nitrogen compound transport 28.5714 4 no
GO:1902531 regulation of intracellular signal transduction 28.5714 5 no
GO:0000165 MAPK cascade 28.5714 4 no
GO:0010941 regulation of cell death 28.5714 4 no
GO:0051493 regulation of cytoskeleton organization 23.8095 6 yes
GO:0010628 positive regulation of gene expression 23.8095 6 no
GO:0048584 positive regulation of response to stimulus 23.8095 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 23.8095 5 no
GO:0051248 negative regulation of protein metabolic process 23.8095 6 no
GO:0080134 regulation of response to stress 23.8095 4 no
GO:0006886 intracellular protein transport 23.8095 4 no
GO:0015031 protein transport 23.8095 4 no
GO:0006357 regulation of transcription by RNA polymerase II 23.8095 7 no
GO:0042981 regulation of apoptotic process 23.8095 6 no
GO:0043067 regulation of programmed cell death 23.8095 5 no
GO:0060548 negative regulation of cell death 23.8095 5 no
GO:0022603 regulation of anatomical structure morphogenesis 19.0476 4 yes
GO:0045595 regulation of cell differentiation 19.0476 4 yes
GO:0051130 positive regulation of cellular component organization 19.0476 5 yes
GO:0044089 positive regulation of cellular component biogenesis 14.2857 5 yes
GO:0051094 positive regulation of developmental process 14.2857 4 yes
GO:0032886 regulation of microtubule-based process 9.5238 4 yes
GO:2000026 regulation of multicellular organismal development 9.5238 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CRK_HUMAN [view entry] [view interactions] High throughput yes no
GLUT4_HUMAN [view interactions] High throughput no no
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
EGLN3_HUMAN [view interactions] High throughput no no
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
RS25_HUMAN [view entry] [view interactions] High throughput yes yes
KI67_HUMAN [view interactions] High throughput no no
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
FXR2_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
TSC2_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
FGFR4_HUMAN [view interactions] High throughput no no
SH3K1_HUMAN [view entry] [view interactions] High throughput yes yes
CCDC8_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
CBX4_HUMAN [view interactions] High throughput no yes
CD2AP_HUMAN [view interactions] High throughput no no
GAN_HUMAN [view interactions] High throughput no yes
LNX1_HUMAN [view interactions] High throughput no yes
WDTC1_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
ZCH18_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
DDX58_HUMAN [view interactions] High throughput no yes
TRIM9_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
SRPK2_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB8_HUMAN [view entry] [view interactions] High throughput yes yes
MLF2_HUMAN [view entry] [view interactions] High throughput yes yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
OCLN_HUMAN [view interactions] High throughput no no
RTEL1_HUMAN [view interactions] Computational no no