CAP2_HUMAN
Evidence for PS localization
Functions
May have a regulatory bifunctional role. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CAP2_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 36.0000 | 4 | no |
| GO:0005524 | ATP binding | 36.0000 | 5 | no |
| GO:0017076 | purine nucleotide binding | 36.0000 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 36.0000 | 6 | no |
| GO:0032555 | purine ribonucleotide binding | 36.0000 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 36.0000 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 36.0000 | 4 | no |
| GO:0043168 | anion binding | 36.0000 | 4 | no |
| GO:0003779 | actin binding | 32.0000 | 4 | yes |
| GO:0008179 | adenylate cyclase binding | 12.0000 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CAP2_HUMAN |
|---|---|---|---|---|
| GO:0006996 | organelle organization | 60.0000 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 56.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 56.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 48.0000 | 4 | no |
| GO:0007010 | cytoskeleton organization | 44.0000 | 5 | yes |
| GO:0022607 | cellular component assembly | 44.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 44.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 44.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 40.0000 | 4 | no |
| GO:0141124 | intracellular signaling cassette | 36.0000 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 36.0000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 36.0000 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 36.0000 | 6 | no |
| GO:0033043 | regulation of organelle organization | 36.0000 | 5 | no |
| GO:0007015 | actin filament organization | 32.0000 | 5 | yes |
| GO:0097435 | supramolecular fiber organization | 32.0000 | 4 | yes |
| GO:0008104 | protein localization | 32.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 32.0000 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 28.0000 | 6 | no |
| GO:0030030 | cell projection organization | 28.0000 | 4 | no |
| GO:0031399 | regulation of protein modification process | 28.0000 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 28.0000 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 28.0000 | 5 | no |
| GO:0043933 | protein-containing complex organization | 28.0000 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 28.0000 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 28.0000 | 6 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 28.0000 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 24.0000 | 7 | no |
| GO:0009893 | positive regulation of metabolic process | 24.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 24.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 24.0000 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 24.0000 | 7 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 24.0000 | 5 | no |
| GO:0032970 | regulation of actin filament-based process | 24.0000 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 24.0000 | 5 | no |
| GO:0110053 | regulation of actin filament organization | 24.0000 | 6 | no |
| GO:0032880 | regulation of protein localization | 24.0000 | 5 | no |
| GO:0060341 | regulation of cellular localization | 24.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 24.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 24.0000 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 24.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 24.0000 | 5 | no |
| GO:0051049 | regulation of transport | 24.0000 | 4 | no |
| GO:0007190 | activation of adenylate cyclase activity | 12.0000 | 7 | yes |
| GO:0019933 | cAMP-mediated signaling | 12.0000 | 5 | yes |
| GO:0031279 | regulation of cyclase activity | 12.0000 | 4 | yes |
| GO:0031281 | positive regulation of cyclase activity | 12.0000 | 5 | yes |
| GO:0043085 | positive regulation of catalytic activity | 12.0000 | 4 | yes |
| GO:0045761 | regulation of adenylate cyclase activity | 12.0000 | 5 | yes |
| GO:0045762 | positive regulation of adenylate cyclase activity | 12.0000 | 6 | yes |
| GO:0051339 | regulation of lyase activity | 12.0000 | 4 | yes |
| GO:0051349 | positive regulation of lyase activity | 12.0000 | 5 | yes |
| GO:0099140 | presynaptic actin cytoskeleton organization | 8.0000 | 4 | yes |
| GO:0099187 | presynaptic cytoskeleton organization | 8.0000 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ACTG_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BCL7A_HUMAN | [view interactions] | High throughput | no | yes |
| BCL7C_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| CNRP1_HUMAN | [view interactions] | High throughput | no | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| CCD40_HUMAN | [view interactions] | High throughput | no | no |
| ACTS_HUMAN | [view interactions] | High throughput | no | no |
| POTEF_HUMAN | [view interactions] | High throughput | no | no |
| POTEJ_HUMAN | [view interactions] | High throughput | no | no |
| BRD2_HUMAN | [view interactions] | High throughput | no | yes |
| BRD3_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPT5H_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MCM4_HUMAN | [view interactions] | High throughput | no | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFKAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDRG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INP4B_HUMAN | [view interactions] | High throughput | no | no |
| AP1G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MSH2_HUMAN | [view interactions] | High throughput | no | yes |
| IF4A1_HUMAN | [view interactions] | High throughput | no | no |
| AP1S1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLGB_HUMAN | [view interactions] | High throughput | no | yes |
| PEPL1_HUMAN | [view interactions] | High throughput | no | yes |
| GOLP3_HUMAN | [view interactions] | High throughput | no | no |
| TRM1_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD2_HUMAN | [view interactions] | High throughput | no | no |
| PR40A_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| POTEI_HUMAN | [view interactions] | High throughput | no | no |
| ACTA_HUMAN | [view interactions] | High throughput | no | no |
| ACTBL_HUMAN | [view interactions] | High throughput | no | no |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TWF2_HUMAN | [view interactions] | High throughput | no | no |
| PK3CA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| MED23_HUMAN | [view interactions] | High throughput | no | no |
| TWF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SERB_HUMAN | [view interactions] | High throughput | no | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AEDO_HUMAN | [view interactions] | High throughput | no | yes |
| HEM1_HUMAN | [view interactions] | High throughput | no | yes |
| GRCR1_HUMAN | [view interactions] | High throughput | no | no |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DSCAM_HUMAN | [view interactions] | High throughput | no | yes |
| COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| STYX_HUMAN | [view interactions] | High throughput | no | yes |