UGPA_HUMAN
Evidence for PS localization
Functions
UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in UGPA_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 30.4348 | 4 | no |
| GO:0046872 | metal ion binding | 26.0870 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 21.7391 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 21.7391 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 21.7391 | 4 | no |
| GO:0045296 | cadherin binding | 21.7391 | 4 | no |
| GO:0003983 | UTP:glucose-1-phosphate uridylyltransferase activity | 8.6957 | 7 | yes |
| GO:0005536 | glucose binding | 8.6957 | 4 | yes |
| GO:0016779 | nucleotidyltransferase activity | 8.6957 | 4 | yes |
| GO:0019103 | pyrimidine nucleotide binding | 8.6957 | 4 | yes |
| GO:0032557 | pyrimidine ribonucleotide binding | 8.6957 | 4 | yes |
| GO:0051748 | UTP-monosaccharide-1-phosphate uridylyltransferase activity | 8.6957 | 6 | yes |
| GO:0070569 | uridylyltransferase activity | 8.6957 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in UGPA_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 43.4783 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 34.7826 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 30.4348 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 30.4348 | 4 | no |
| GO:0010646 | regulation of cell communication | 30.4348 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 26.0870 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 26.0870 | 5 | no |
| GO:0009966 | regulation of signal transduction | 26.0870 | 4 | no |
| GO:0010468 | regulation of gene expression | 26.0870 | 5 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 26.0870 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 26.0870 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.0870 | 5 | no |
| GO:0005976 | polysaccharide metabolic process | 21.7391 | 4 | yes |
| GO:0005977 | glycogen metabolic process | 21.7391 | 6 | yes |
| GO:0006073 | cellular glucan metabolic process | 21.7391 | 5 | yes |
| GO:0006112 | energy reserve metabolic process | 21.7391 | 5 | yes |
| GO:0015980 | energy derivation by oxidation of organic compounds | 21.7391 | 4 | yes |
| GO:0044042 | glucan metabolic process | 21.7391 | 5 | yes |
| GO:0044264 | cellular polysaccharide metabolic process | 21.7391 | 4 | yes |
| GO:0009057 | macromolecule catabolic process | 21.7391 | 4 | no |
| GO:0036211 | protein modification process | 21.7391 | 4 | no |
| GO:0043412 | macromolecule modification | 21.7391 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 21.7391 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 21.7391 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 21.7391 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.7391 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 21.7391 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 21.7391 | 6 | no |
| GO:0051128 | regulation of cellular component organization | 21.7391 | 4 | no |
| GO:0009059 | macromolecule biosynthetic process | 17.3913 | 4 | yes |
| GO:0034645 | cellular macromolecule biosynthetic process | 17.3913 | 4 | yes |
| GO:0000271 | polysaccharide biosynthetic process | 13.0435 | 5 | yes |
| GO:0005978 | glycogen biosynthetic process | 13.0435 | 7 | yes |
| GO:0009250 | glucan biosynthetic process | 13.0435 | 6 | yes |
| GO:0016051 | carbohydrate biosynthetic process | 13.0435 | 4 | yes |
| GO:0033692 | cellular polysaccharide biosynthetic process | 13.0435 | 5 | yes |
| GO:0034637 | cellular carbohydrate biosynthetic process | 13.0435 | 4 | yes |
| GO:0006011 | UDP-glucose metabolic process | 8.6957 | 4 | yes |
| GO:0007420 | brain development | 8.6957 | 4 | yes |
| GO:0009225 | nucleotide-sugar metabolic process | 8.6957 | 4 | yes |
| GO:0019255 | glucose 1-phosphate metabolic process | 8.6957 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| UGPA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ABCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T2EB_HUMAN | [view interactions] | High throughput | no | yes |
| SUN2_HUMAN | [view interactions] | High throughput | no | yes |
| DCA15_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUF60_HUMAN | [view interactions] | High throughput | no | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| CBS_HUMAN | [view interactions] | High throughput | no | yes |
| GLRX3_HUMAN | [view interactions] | High throughput | no | yes |
| ARI2_HUMAN | [view interactions] | High throughput | no | no |
| PKHF2_HUMAN | [view interactions] | High throughput | no | yes |
| KLF11_HUMAN | [view interactions] | High throughput | no | no |
| CSAG2_HUMAN | [view interactions] | High throughput | no | no |
| TITIN_HUMAN | [view interactions] | High throughput | no | no |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC7_HUMAN | [view interactions] | High throughput | no | no |
| SNX24_HUMAN | [view interactions] | High throughput | no | yes |
| GPSM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAF1B_HUMAN | [view interactions] | High throughput | no | no |
| S10A6_HUMAN | [view interactions] | High throughput | no | yes |
| CR021_HUMAN | [view interactions] | High throughput | no | no |
| SSUH2_HUMAN | [view interactions] | High throughput | no | no |
| PLCA_HUMAN | [view interactions] | High throughput | no | yes |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPRNG_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| DNPEP_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| MRO2B_HUMAN | [view interactions] | High throughput | no | no |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| SYFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR2_HUMAN | [view interactions] | High throughput | no | yes |
| HIRP3_HUMAN | [view interactions] | High throughput | no | no |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| NUSAP_HUMAN | [view interactions] | High throughput | no | no |
| PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAPOA_HUMAN | [view interactions] | High throughput | no | yes |
| PARVA_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1G_HUMAN | [view interactions] | High throughput | no | no |
| 2A5G_HUMAN | [view interactions] | High throughput | no | yes |
| RANB3_HUMAN | [view interactions] | High throughput | no | yes |
| SET_HUMAN | [view interactions] | High throughput | no | yes |
| SYTC_HUMAN | [view interactions] | High throughput | no | yes |
| RO60_HUMAN | [view interactions] | High throughput | no | yes |
| BUB1B_HUMAN | [view interactions] | High throughput | no | no |
| CARM1_HUMAN | [view interactions] | High throughput | no | yes |
| C2D1B_HUMAN | [view interactions] | High throughput | no | yes |
| CSDE1_HUMAN | [view interactions] | High throughput | no | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN12_HUMAN | [view interactions] | High throughput | no | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VASN_HUMAN | [view interactions] | High throughput | no | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| A16A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLPK2_HUMAN | [view interactions] | High throughput | no | no |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| KHK_HUMAN | [view interactions] | High throughput | no | no |
| HXK4_HUMAN | [view interactions] | High throughput | no | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGM2_HUMAN | [view interactions] | Computational | no | no |
| GYS1_HUMAN | [view interactions] | Computational | no | yes |
| GLYG_HUMAN | [view interactions] | Computational | no | yes |
| GDE_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PGM1_HUMAN | [view interactions] | Computational | no | no |
| PGM5_HUMAN | [view interactions] | Computational | no | no |
| GALT_HUMAN | [view interactions] | Computational | no | yes |
| GYS2_HUMAN | [view interactions] | Computational | no | no |
| PYGM_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ENPP3_HUMAN | [view interactions] | Computational | no | no |
| PYGL_HUMAN | [view interactions] | Computational | no | yes |
| GALE_HUMAN | [view interactions] | Computational | no | no |
| PGM2L_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GLGB_HUMAN | [view interactions] | Computational | no | yes |
| PYGB_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| GLYG2_HUMAN | [view interactions] | Computational | no | no |
| PASK_HUMAN | [view interactions] | Computational | no | yes |
| UGDH_HUMAN | [view interactions] | Computational | no | no |