UGPA_HUMAN
Evidence for PS localization
Functions
UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in UGPA_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 43.4783 | 4 | yes |
| GO:0003723 | RNA binding | 43.4783 | 4 | no |
| GO:0043168 | anion binding | 39.1304 | 4 | no |
| GO:0017076 | purine nucleotide binding | 34.7826 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 34.7826 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 34.7826 | 4 | no |
| GO:0005524 | ATP binding | 30.4348 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 30.4348 | 6 | no |
| GO:0031625 | ubiquitin protein ligase binding | 30.4348 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 30.4348 | 5 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 30.4348 | 4 | no |
| GO:0043169 | cation binding | 26.0870 | 4 | yes |
| GO:0046872 | metal ion binding | 26.0870 | 5 | yes |
| GO:0045296 | cadherin binding | 26.0870 | 4 | no |
| GO:0003983 | UTP:glucose-1-phosphate uridylyltransferase activity | 8.6957 | 7 | yes |
| GO:0005536 | glucose binding | 8.6957 | 4 | yes |
| GO:0016779 | nucleotidyltransferase activity | 8.6957 | 4 | yes |
| GO:0019103 | pyrimidine nucleotide binding | 8.6957 | 5 | yes |
| GO:0032557 | pyrimidine ribonucleotide binding | 8.6957 | 4 | yes |
| GO:0051748 | UTP-monosaccharide-1-phosphate uridylyltransferase activity | 8.6957 | 6 | yes |
| GO:0070569 | uridylyltransferase activity | 8.6957 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in UGPA_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.8696 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 56.5217 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 52.1739 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 52.1739 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 47.8261 | 4 | no |
| GO:0010646 | regulation of cell communication | 47.8261 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 47.8261 | 4 | no |
| GO:0009966 | regulation of signal transduction | 43.4783 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 43.4783 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 43.4783 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 43.4783 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 43.4783 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 43.4783 | 4 | no |
| GO:0010468 | regulation of gene expression | 39.1304 | 6 | no |
| GO:0048523 | negative regulation of cellular process | 39.1304 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 39.1304 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 39.1304 | 5 | no |
| GO:0002684 | positive regulation of immune system process | 34.7826 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 34.7826 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 34.7826 | 5 | no |
| GO:0023056 | positive regulation of signaling | 34.7826 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 34.7826 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 34.7826 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 34.7826 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 34.7826 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 34.7826 | 5 | no |
| GO:0006996 | organelle organization | 34.7826 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 34.7826 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 34.7826 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 34.7826 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 34.7826 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 30.4348 | 6 | no |
| GO:0036211 | protein modification process | 30.4348 | 4 | no |
| GO:0043412 | macromolecule modification | 30.4348 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 30.4348 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 30.4348 | 6 | no |
| GO:0080134 | regulation of response to stress | 30.4348 | 4 | no |
| GO:0022607 | cellular component assembly | 30.4348 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.4348 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 30.4348 | 5 | no |
| GO:0090304 | nucleic acid metabolic process | 30.4348 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 26.0870 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 26.0870 | 5 | no |
| GO:0023057 | negative regulation of signaling | 26.0870 | 4 | no |
| GO:0030162 | regulation of proteolysis | 26.0870 | 6 | no |
| GO:0031347 | regulation of defense response | 26.0870 | 5 | no |
| GO:0031349 | positive regulation of defense response | 26.0870 | 5 | no |
| GO:0032101 | regulation of response to external stimulus | 26.0870 | 4 | no |
| GO:0032103 | positive regulation of response to external stimulus | 26.0870 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.0870 | 4 | no |
| GO:0050776 | regulation of immune response | 26.0870 | 4 | no |
| GO:0050778 | positive regulation of immune response | 26.0870 | 5 | no |
| GO:0071310 | cellular response to organic substance | 26.0870 | 4 | no |
| GO:0007010 | cytoskeleton organization | 26.0870 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 26.0870 | 7 | no |
| GO:0009894 | regulation of catabolic process | 26.0870 | 4 | no |
| GO:0009896 | positive regulation of catabolic process | 26.0870 | 5 | no |
| GO:0010628 | positive regulation of gene expression | 26.0870 | 7 | no |
| GO:0016070 | RNA metabolic process | 26.0870 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 26.0870 | 6 | no |
| GO:0009059 | macromolecule biosynthetic process | 26.0870 | 4 | yes |
| GO:0001817 | regulation of cytokine production | 21.7391 | 4 | no |
| GO:0002831 | regulation of response to biotic stimulus | 21.7391 | 4 | no |
| GO:0002833 | positive regulation of response to biotic stimulus | 21.7391 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 21.7391 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 21.7391 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 21.7391 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 21.7391 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 21.7391 | 7 | no |
| GO:0042127 | regulation of cell population proliferation | 21.7391 | 4 | no |
| GO:0045088 | regulation of innate immune response | 21.7391 | 5 | no |
| GO:0045089 | positive regulation of innate immune response | 21.7391 | 6 | no |
| GO:0045595 | regulation of cell differentiation | 21.7391 | 4 | no |
| GO:0045862 | positive regulation of proteolysis | 21.7391 | 7 | no |
| GO:0051049 | regulation of transport | 21.7391 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 21.7391 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 21.7391 | 5 | no |
| GO:0010638 | positive regulation of organelle organization | 21.7391 | 6 | no |
| GO:0031334 | positive regulation of protein-containing complex assembly | 21.7391 | 6 | no |
| GO:0033043 | regulation of organelle organization | 21.7391 | 5 | no |
| GO:0043254 | regulation of protein-containing complex assembly | 21.7391 | 5 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 21.7391 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 21.7391 | 6 | no |
| GO:0043687 | post-translational protein modification | 21.7391 | 5 | no |
| GO:0043933 | protein-containing complex organization | 21.7391 | 4 | no |
| GO:0070647 | protein modification by small protein conjugation or removal | 21.7391 | 6 | no |
| GO:0009057 | macromolecule catabolic process | 21.7391 | 4 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 21.7391 | 5 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 21.7391 | 5 | no |
| GO:0009250 | glucan biosynthetic process | 8.6957 | 6 | yes |
| GO:0015980 | energy derivation by oxidation of organic compounds | 8.6957 | 4 | yes |
| GO:0016051 | carbohydrate biosynthetic process | 8.6957 | 4 | yes |
| GO:0019255 | glucose 1-phosphate metabolic process | 8.6957 | 4 | yes |
| GO:0044042 | glucan metabolic process | 8.6957 | 5 | yes |
| GO:0000271 | polysaccharide biosynthetic process | 8.6957 | 5 | yes |
| GO:0005976 | polysaccharide metabolic process | 8.6957 | 4 | yes |
| GO:0005977 | glycogen metabolic process | 8.6957 | 6 | yes |
| GO:0005978 | glycogen biosynthetic process | 8.6957 | 7 | yes |
| GO:0006011 | UDP-glucose metabolic process | 8.6957 | 4 | yes |
| GO:0006112 | energy reserve metabolic process | 8.6957 | 5 | yes |
| GO:0007420 | brain development | 8.6957 | 4 | yes |
| GO:0009225 | nucleotide-sugar metabolic process | 8.6957 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| UGPA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ABCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T2EB_HUMAN | [view interactions] | High throughput | no | yes |
| SUN2_HUMAN | [view interactions] | High throughput | no | yes |
| DCA15_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUF60_HUMAN | [view interactions] | High throughput | no | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| CBS_HUMAN | [view interactions] | High throughput | no | yes |
| GLRX3_HUMAN | [view interactions] | High throughput | no | yes |
| ARI2_HUMAN | [view interactions] | High throughput | no | no |
| PKHF2_HUMAN | [view interactions] | High throughput | no | yes |
| KLF11_HUMAN | [view interactions] | High throughput | no | no |
| CSAG2_HUMAN | [view interactions] | High throughput | no | no |
| TITIN_HUMAN | [view interactions] | High throughput | no | no |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC7_HUMAN | [view interactions] | High throughput | no | no |
| SNX24_HUMAN | [view interactions] | High throughput | no | yes |
| GPSM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAF1B_HUMAN | [view interactions] | High throughput | no | no |
| S10A6_HUMAN | [view interactions] | High throughput | no | yes |
| CR021_HUMAN | [view interactions] | High throughput | no | no |
| SSUH2_HUMAN | [view interactions] | High throughput | no | no |
| PLCA_HUMAN | [view interactions] | High throughput | no | yes |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| MYO10_HUMAN | [view interactions] | High throughput | no | no |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPRNG_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| SPPL3_HUMAN | [view interactions] | High throughput | no | no |
| DNPEP_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| MRO2B_HUMAN | [view interactions] | High throughput | no | no |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| SYFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR2_HUMAN | [view interactions] | High throughput | no | yes |
| HIRP3_HUMAN | [view interactions] | High throughput | no | no |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| NUSAP_HUMAN | [view interactions] | High throughput | no | no |
| PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAPOA_HUMAN | [view interactions] | High throughput | no | yes |
| PARVA_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1G_HUMAN | [view interactions] | High throughput | no | no |
| 2A5G_HUMAN | [view interactions] | High throughput | no | yes |
| RANB3_HUMAN | [view interactions] | High throughput | no | yes |
| SET_HUMAN | [view interactions] | High throughput | no | yes |
| SYTC_HUMAN | [view interactions] | High throughput | no | yes |
| RO60_HUMAN | [view interactions] | High throughput | no | yes |
| BUB1B_HUMAN | [view interactions] | High throughput | no | no |
| CARM1_HUMAN | [view interactions] | High throughput | no | yes |
| C2D1B_HUMAN | [view interactions] | High throughput | no | yes |
| CSDE1_HUMAN | [view interactions] | High throughput | no | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN12_HUMAN | [view interactions] | High throughput | no | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VASN_HUMAN | [view interactions] | High throughput | no | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| A16A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLPK2_HUMAN | [view interactions] | High throughput | no | no |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| KHK_HUMAN | [view interactions] | High throughput | no | no |
| HXK4_HUMAN | [view interactions] | High throughput | no | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESTD_HUMAN | [view interactions] | High throughput | no | yes |
| ECI1_HUMAN | [view interactions] | High throughput | no | yes |
| PIPNB_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |