Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

INP4A_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Displays no 4-phosphatase activity for PtdIns(3,4)P2, Ins(3,4)P2, or Ins(1,3,4)P3. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in INP4A_HUMAN
GO:0016755 aminoacyltransferase activity 50.0000 4 no
GO:0004842 ubiquitin-protein transferase activity 37.5000 4 no
GO:0031625 ubiquitin protein ligase binding 37.5000 5 no
GO:0044389 ubiquitin-like protein ligase binding 37.5000 4 no
GO:0061659 ubiquitin-like protein ligase activity 37.5000 4 no
GO:0043169 cation binding 25.0000 4 no
GO:0046872 metal ion binding 25.0000 5 no
GO:0061630 ubiquitin protein ligase activity 25.0000 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in INP4A_HUMAN
GO:0009057 macromolecule catabolic process 62.5000 4 no
GO:0036211 protein modification process 62.5000 4 no
GO:0043412 macromolecule modification 62.5000 4 no
GO:0006996 organelle organization 62.5000 4 no
GO:0060255 regulation of macromolecule metabolic process 62.5000 4 no
GO:0080090 regulation of primary metabolic process 62.5000 4 no
GO:0006508 proteolysis 50.0000 4 no
GO:0006511 ubiquitin-dependent protein catabolic process 50.0000 7 no
GO:0016567 protein ubiquitination 50.0000 8 no
GO:0019941 modification-dependent protein catabolic process 50.0000 6 no
GO:0030163 protein catabolic process 50.0000 4 no
GO:0032446 protein modification by small protein conjugation 50.0000 7 no
GO:0043632 modification-dependent macromolecule catabolic process 50.0000 5 no
GO:0043687 post-translational protein modification 50.0000 5 no
GO:0051603 proteolysis involved in protein catabolic process 50.0000 5 no
GO:0070647 protein modification by small protein conjugation or removal 50.0000 6 no
GO:1901565 organonitrogen compound catabolic process 50.0000 4 no
GO:0009889 regulation of biosynthetic process 50.0000 4 no
GO:0009894 regulation of catabolic process 50.0000 4 no
GO:0010468 regulation of gene expression 50.0000 6 no
GO:0010556 regulation of macromolecule biosynthetic process 50.0000 5 no
GO:0022607 cellular component assembly 50.0000 4 no
GO:0031323 regulation of cellular metabolic process 50.0000 4 no
GO:0031326 regulation of cellular biosynthetic process 50.0000 5 no
GO:0051128 regulation of cellular component organization 50.0000 4 no
GO:0051246 regulation of protein metabolic process 50.0000 5 no
GO:0009966 regulation of signal transduction 50.0000 4 no
GO:0009967 positive regulation of signal transduction 50.0000 5 no
GO:0010646 regulation of cell communication 50.0000 4 no
GO:0010647 positive regulation of cell communication 50.0000 5 no
GO:0023056 positive regulation of signaling 50.0000 4 no
GO:0048522 positive regulation of cellular process 50.0000 4 no
GO:0048584 positive regulation of response to stimulus 50.0000 4 no
GO:0000082 G1/S transition of mitotic cell cycle 37.5000 5 no
GO:0010498 proteasomal protein catabolic process 37.5000 5 no
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 37.5000 6 no
GO:0044772 mitotic cell cycle phase transition 37.5000 4 no
GO:0044843 cell cycle G1/S phase transition 37.5000 4 no
GO:0007005 mitochondrion organization 37.5000 5 no
GO:0009890 negative regulation of biosynthetic process 37.5000 5 no
GO:0009892 negative regulation of metabolic process 37.5000 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 37.5000 6 no
GO:0010605 negative regulation of macromolecule metabolic process 37.5000 5 no
GO:0010629 negative regulation of gene expression 37.5000 7 no
GO:0031324 negative regulation of cellular metabolic process 37.5000 5 no
GO:0031327 negative regulation of cellular biosynthetic process 37.5000 6 no
GO:0031396 regulation of protein ubiquitination 37.5000 9 no
GO:0031399 regulation of protein modification process 37.5000 6 no
GO:0033043 regulation of organelle organization 37.5000 5 no
GO:0042981 regulation of apoptotic process 37.5000 5 no
GO:0043067 regulation of programmed cell death 37.5000 4 no
GO:0043933 protein-containing complex organization 37.5000 4 no
GO:0048523 negative regulation of cellular process 37.5000 4 no
GO:0048585 negative regulation of response to stimulus 37.5000 4 no
GO:0051046 regulation of secretion 37.5000 5 no
GO:0051049 regulation of transport 37.5000 4 no
GO:0051050 positive regulation of transport 37.5000 4 no
GO:1901873 regulation of post-translational protein modification 37.5000 7 no
GO:1903320 regulation of protein modification by small protein conjugation or removal 37.5000 8 no
GO:0006355 regulation of DNA-templated transcription 37.5000 7 no
GO:0009893 positive regulation of metabolic process 37.5000 4 no
GO:0010604 positive regulation of macromolecule metabolic process 37.5000 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 37.5000 5 no
GO:0050804 modulation of chemical synaptic transmission 37.5000 5 no
GO:0051130 positive regulation of cellular component organization 37.5000 5 no
GO:0051247 positive regulation of protein metabolic process 37.5000 6 no
GO:0051252 regulation of RNA metabolic process 37.5000 5 no
GO:0071310 cellular response to organic substance 37.5000 4 no
GO:0099177 regulation of trans-synaptic signaling 37.5000 4 no
GO:2001141 regulation of RNA biosynthetic process 37.5000 6 no
GO:0006796 phosphate-containing compound metabolic process 25.0000 4 yes
GO:0008610 lipid biosynthetic process 25.0000 4 yes
GO:0097193 intrinsic apoptotic signaling pathway 25.0000 4 no
GO:0000422 autophagy of mitochondrion 25.0000 4 no
GO:0001817 regulation of cytokine production 25.0000 4 no
GO:0001818 negative regulation of cytokine production 25.0000 5 no
GO:0006915 apoptotic process 25.0000 4 no
GO:0009059 macromolecule biosynthetic process 25.0000 4 no
GO:0010038 response to metal ion 25.0000 4 no
GO:0010506 regulation of autophagy 25.0000 6 no
GO:0010660 regulation of muscle cell apoptotic process 25.0000 6 no
GO:0010662 regulation of striated muscle cell apoptotic process 25.0000 7 no
GO:0010665 regulation of cardiac muscle cell apoptotic process 25.0000 8 no
GO:0010959 regulation of metal ion transport 25.0000 6 no
GO:0016236 macroautophagy 25.0000 4 no
GO:0022411 cellular component disassembly 25.0000 4 no
GO:0030100 regulation of endocytosis 25.0000 5 no
GO:0031329 regulation of cellular catabolic process 25.0000 5 no
GO:0031344 regulation of cell projection organization 25.0000 5 no
GO:0031400 negative regulation of protein modification process 25.0000 7 no
GO:0032479 regulation of type I interferon production 25.0000 5 no
GO:0032480 negative regulation of type I interferon production 25.0000 6 no
GO:0043066 negative regulation of apoptotic process 25.0000 6 no
GO:0043069 negative regulation of programmed cell death 25.0000 5 no
GO:0043269 regulation of monoatomic ion transport 25.0000 5 no
GO:0044087 regulation of cellular component biogenesis 25.0000 4 no
GO:0051051 negative regulation of transport 25.0000 4 no
GO:0051129 negative regulation of cellular component organization 25.0000 5 no
GO:0051240 positive regulation of multicellular organismal process 25.0000 4 no
GO:0051241 negative regulation of multicellular organismal process 25.0000 4 no
GO:0051248 negative regulation of protein metabolic process 25.0000 6 no
GO:0051924 regulation of calcium ion transport 25.0000 7 no
GO:0060627 regulation of vesicle-mediated transport 25.0000 4 no
GO:0062197 cellular response to chemical stress 25.0000 4 no
GO:0070925 organelle assembly 25.0000 5 no
GO:0080134 regulation of response to stress 25.0000 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 25.0000 6 no
GO:1903008 organelle disassembly 25.0000 5 no
GO:2000377 regulation of reactive oxygen species metabolic process 25.0000 5 no
GO:2000378 negative regulation of reactive oxygen species metabolic process 25.0000 6 no
GO:0000122 negative regulation of transcription by RNA polymerase II 25.0000 9 no
GO:0000209 protein polyubiquitination 25.0000 9 no
GO:0001558 regulation of cell growth 25.0000 4 no
GO:0006357 regulation of transcription by RNA polymerase II 25.0000 8 no
GO:0006513 protein monoubiquitination 25.0000 9 no
GO:0008104 protein localization 25.0000 4 no
GO:0009896 positive regulation of catabolic process 25.0000 5 no
GO:0009968 negative regulation of signal transduction 25.0000 5 no
GO:0010638 positive regulation of organelle organization 25.0000 6 no
GO:0010648 negative regulation of cell communication 25.0000 5 no
GO:0022603 regulation of anatomical structure morphogenesis 25.0000 4 no
GO:0023057 negative regulation of signaling 25.0000 4 no
GO:0030111 regulation of Wnt signaling pathway 25.0000 5 no
GO:0030162 regulation of proteolysis 25.0000 6 no
GO:0030307 positive regulation of cell growth 25.0000 5 no
GO:0031398 positive regulation of protein ubiquitination 25.0000 10 no
GO:0031401 positive regulation of protein modification process 25.0000 7 no
GO:0031648 protein destabilization 25.0000 4 no
GO:0033365 protein localization to organelle 25.0000 5 no
GO:0043086 negative regulation of catalytic activity 25.0000 4 no
GO:0043393 regulation of protein binding 25.0000 4 no
GO:0044788 modulation by host of viral process 25.0000 5 no
GO:0045862 positive regulation of proteolysis 25.0000 7 no
GO:0045892 negative regulation of DNA-templated transcription 25.0000 8 no
GO:0045927 positive regulation of growth 25.0000 4 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 25.0000 5 no
GO:0046928 regulation of neurotransmitter secretion 25.0000 5 no
GO:0048638 regulation of developmental growth 25.0000 4 no
GO:0048639 positive regulation of developmental growth 25.0000 5 no
GO:0051094 positive regulation of developmental process 25.0000 4 no
GO:0051253 negative regulation of RNA metabolic process 25.0000 6 no
GO:0051588 regulation of neurotransmitter transport 25.0000 5 no
GO:0051851 modulation by host of symbiont process 25.0000 4 no
GO:0051865 protein autoubiquitination 25.0000 9 no
GO:0065003 protein-containing complex assembly 25.0000 5 no
GO:0070936 protein K48-linked ubiquitination 25.0000 10 no
GO:0097435 supramolecular fiber organization 25.0000 4 no
GO:0140250 regulation protein catabolic process at synapse 25.0000 5 no
GO:1901875 positive regulation of post-translational protein modification 25.0000 8 no
GO:1902531 regulation of intracellular signal transduction 25.0000 5 no
GO:1902532 negative regulation of intracellular signal transduction 25.0000 6 no
GO:1902533 positive regulation of intracellular signal transduction 25.0000 6 no
GO:1902679 negative regulation of RNA biosynthetic process 25.0000 7 no
GO:1903050 regulation of proteolysis involved in protein catabolic process 25.0000 7 no
GO:1903052 positive regulation of proteolysis involved in protein catabolic process 25.0000 8 no
GO:1903322 positive regulation of protein modification by small protein conjugation or removal 25.0000 9 no
GO:1903530 regulation of secretion by cell 25.0000 4 no
GO:2000058 regulation of ubiquitin-dependent protein catabolic process 25.0000 5 no
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 25.0000 6 no
GO:0006954 inflammatory response 25.0000 4 no
GO:0034097 response to cytokine 25.0000 4 no
GO:0071345 cellular response to cytokine stimulus 25.0000 5 no
GO:0007010 cytoskeleton organization 25.0000 5 no
GO:0008284 positive regulation of cell population proliferation 25.0000 5 no
GO:0016055 Wnt signaling pathway 25.0000 4 no
GO:0030030 cell projection organization 25.0000 4 no
GO:0042127 regulation of cell population proliferation 25.0000 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SMAD1_HUMAN [view interactions] High throughput no yes
HDAC4_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
CD81_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
NXT2_HUMAN [view interactions] High throughput no yes
NTAQ1_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
INS_HUMAN [view interactions] High throughput no no
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
HXK3_HUMAN [view interactions] High throughput no no
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ATG5_HUMAN [view entry] [view interactions] High throughput yes no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
FAS_HUMAN [view entry] [view interactions] High throughput yes no
LDLR_HUMAN [view interactions] High throughput no yes
SRBP2_HUMAN [view interactions] High throughput no yes
HERC2_HUMAN [view interactions] High throughput no yes
KDM1A_HUMAN [view interactions] High throughput no yes