INP4A_HUMAN
Evidence for PS localization
Functions
Displays no 4-phosphatase activity for PtdIns(3,4)P2, Ins(3,4)P2, or Ins(1,3,4)P3. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in INP4A_HUMAN |
|---|---|---|---|---|
| GO:0016791 | phosphatase activity | 60.0000 | 5 | yes |
| GO:0042578 | phosphoric ester hydrolase activity | 60.0000 | 4 | yes |
| GO:0052866 | phosphatidylinositol phosphate phosphatase activity | 50.0000 | 6 | yes |
| GO:0034593 | phosphatidylinositol bisphosphate phosphatase activity | 40.0000 | 7 | yes |
| GO:0004438 | phosphatidylinositol-3-phosphatase activity | 40.0000 | 8 | no |
| GO:0052744 | phosphatidylinositol monophosphate phosphatase activity | 40.0000 | 7 | no |
| GO:0034596 | phosphatidylinositol phosphate 4-phosphatase activity | 30.0000 | 7 | yes |
| GO:0052745 | inositol phosphate phosphatase activity | 30.0000 | 6 | yes |
| GO:0106017 | phosphatidylinositol-3,4-bisphosphate phosphatase activity | 20.0000 | 8 | yes |
| GO:0106019 | phosphatidylinositol-4,5-bisphosphate phosphatase activity | 20.0000 | 8 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in INP4A_HUMAN |
|---|---|---|---|---|
| GO:0006796 | phosphate-containing compound metabolic process | 70.0000 | 4 | yes |
| GO:0008610 | lipid biosynthetic process | 70.0000 | 4 | yes |
| GO:0006644 | phospholipid metabolic process | 60.0000 | 4 | yes |
| GO:0006650 | glycerophospholipid metabolic process | 60.0000 | 5 | yes |
| GO:0006661 | phosphatidylinositol biosynthetic process | 60.0000 | 6 | yes |
| GO:0008654 | phospholipid biosynthetic process | 60.0000 | 4 | yes |
| GO:0045017 | glycerolipid biosynthetic process | 60.0000 | 4 | yes |
| GO:0046474 | glycerophospholipid biosynthetic process | 60.0000 | 5 | yes |
| GO:0046486 | glycerolipid metabolic process | 60.0000 | 4 | yes |
| GO:0046488 | phosphatidylinositol metabolic process | 60.0000 | 6 | yes |
| GO:0090407 | organophosphate biosynthetic process | 60.0000 | 4 | yes |
| GO:0019751 | polyol metabolic process | 40.0000 | 4 | yes |
| GO:0043647 | inositol phosphate metabolic process | 40.0000 | 4 | yes |
| GO:0016311 | dephosphorylation | 40.0000 | 5 | no |
| GO:0036211 | protein modification process | 30.0000 | 4 | no |
| GO:0043412 | macromolecule modification | 30.0000 | 4 | no |
| GO:0006996 | organelle organization | 30.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 30.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 30.0000 | 4 | no |
| GO:0030258 | lipid modification | 30.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 30.0000 | 4 | no |
| GO:0046164 | alcohol catabolic process | 30.0000 | 4 | no |
| GO:0046174 | polyol catabolic process | 30.0000 | 5 | no |
| GO:0046434 | organophosphate catabolic process | 30.0000 | 4 | no |
| GO:0046838 | phosphorylated carbohydrate dephosphorylation | 30.0000 | 4 | no |
| GO:0046839 | phospholipid dephosphorylation | 30.0000 | 5 | no |
| GO:0046855 | inositol phosphate dephosphorylation | 30.0000 | 5 | no |
| GO:0046856 | phosphatidylinositol dephosphorylation | 30.0000 | 6 | no |
| GO:0048522 | positive regulation of cellular process | 30.0000 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 30.0000 | 5 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 30.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 30.0000 | 4 | no |
| GO:0061024 | membrane organization | 30.0000 | 4 | no |
| GO:0071545 | inositol phosphate catabolic process | 30.0000 | 5 | no |
| GO:0080090 | regulation of primary metabolic process | 30.0000 | 4 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 30.0000 | 4 | no |
| GO:1901616 | organic hydroxy compound catabolic process | 30.0000 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NXT2_HUMAN | [view interactions] | High throughput | no | yes |
| NTAQ1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| CUL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HXK3_HUMAN | [view interactions] | High throughput | no | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LDLR_HUMAN | [view interactions] | High throughput | no | yes |
| SRBP2_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| P3C2B_HUMAN | [view interactions] | Computational | no | no |
| P85B_HUMAN | [view interactions] | Computational | no | yes |
| SAC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ITPK1_HUMAN | [view interactions] | Computational | no | yes |
| FYV1_HUMAN | [view interactions] | Computational | no | no |
| IMPA3_HUMAN | [view interactions] | Computational | no | yes |
| SYNJ2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SHIP1_HUMAN | [view interactions] | Computational | no | no |
| IMPA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MTMRE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| P3C2A_HUMAN | [view interactions] | Computational | no | yes |
| INP4B_HUMAN | [view interactions] | Computational | no | no |
| INO1_HUMAN | [view interactions] | Computational | no | no |
| I5P1_HUMAN | [view interactions] | Computational | no | yes |
| INP5K_HUMAN | [view interactions] | Computational | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| OCRL_HUMAN | [view interactions] | Computational | no | yes |
| INP5E_HUMAN | [view interactions] | Computational | no | yes |
| P55G_HUMAN | [view interactions] | Computational | no | yes |
| FIG4_HUMAN | [view interactions] | Computational | no | yes |
| SHIP2_HUMAN | [view interactions] | Computational | no | yes |
| I5P2_HUMAN | [view interactions] | Computational | no | yes |
| MTMR3_HUMAN | [view interactions] | Computational | no | no |
| PK3C3_HUMAN | [view interactions] | Computational | no | yes |
| MTM1_HUMAN | [view interactions] | Computational | no | yes |
| P85A_HUMAN | [view interactions] | Computational | no | yes |
| IMPA2_HUMAN | [view interactions] | Computational | no | no |
| INPP_HUMAN | [view interactions] | Computational | no | no |