Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

GNPAT_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Dihydroxyacetonephosphate acyltransferase involved in plasmalogen biosynthesis. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
211 Arg Cys Rhizomelicchondrodysplasiapunctata2(RCDP2) -
211 Arg His Rhizomelicchondrodysplasiapunctata2(RCDP2) -
519 Asp Gly Rhizomelicchondrodysplasiapunctata2(RCDP2) -

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in GNPAT_HUMAN
GO:0043169 cation binding 33.3333 4 no
GO:0046872 metal ion binding 33.3333 5 no
GO:0004366 glycerol-3-phosphate O-acyltransferase activity 13.3333 6 yes
GO:0008374 O-acyltransferase activity 13.3333 5 yes
GO:0016287 glycerone-phosphate O-acyltransferase activity 13.3333 7 yes
GO:0016407 acetyltransferase activity 13.3333 5 yes
GO:0016413 O-acetyltransferase activity 13.3333 6 yes
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 13.3333 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in GNPAT_HUMAN
GO:0060255 regulation of macromolecule metabolic process 60.0000 4 no
GO:0048522 positive regulation of cellular process 53.3333 4 no
GO:0031323 regulation of cellular metabolic process 53.3333 4 no
GO:0048523 negative regulation of cellular process 46.6667 4 no
GO:0048584 positive regulation of response to stimulus 46.6667 4 no
GO:0051128 regulation of cellular component organization 46.6667 4 no
GO:0051246 regulation of protein metabolic process 46.6667 5 no
GO:0080090 regulation of primary metabolic process 46.6667 4 no
GO:0009889 regulation of biosynthetic process 46.6667 4 no
GO:0010468 regulation of gene expression 46.6667 6 no
GO:0010556 regulation of macromolecule biosynthetic process 46.6667 5 no
GO:0031326 regulation of cellular biosynthetic process 46.6667 5 no
GO:0022607 cellular component assembly 46.6667 4 yes
GO:0009893 positive regulation of metabolic process 46.6667 4 no
GO:0009966 regulation of signal transduction 46.6667 4 no
GO:0010646 regulation of cell communication 46.6667 4 no
GO:0043067 regulation of programmed cell death 40.0000 4 no
GO:0051049 regulation of transport 40.0000 4 no
GO:0051240 positive regulation of multicellular organismal process 40.0000 4 no
GO:1902531 regulation of intracellular signal transduction 40.0000 5 no
GO:0001817 regulation of cytokine production 40.0000 4 no
GO:0008104 protein localization 40.0000 4 no
GO:0009967 positive regulation of signal transduction 40.0000 5 no
GO:0010604 positive regulation of macromolecule metabolic process 40.0000 5 no
GO:0010647 positive regulation of cell communication 40.0000 5 no
GO:0023056 positive regulation of signaling 40.0000 4 no
GO:0042981 regulation of apoptotic process 40.0000 5 no
GO:0043069 negative regulation of programmed cell death 33.3333 5 no
GO:0048585 negative regulation of response to stimulus 33.3333 4 no
GO:0051130 positive regulation of cellular component organization 33.3333 5 no
GO:0051241 negative regulation of multicellular organismal process 33.3333 4 no
GO:1902533 positive regulation of intracellular signal transduction 33.3333 6 no
GO:0009892 negative regulation of metabolic process 33.3333 4 no
GO:0010605 negative regulation of macromolecule metabolic process 33.3333 5 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0071702 organic substance transport 33.3333 4 no
GO:0071705 nitrogen compound transport 33.3333 4 no
GO:0031325 positive regulation of cellular metabolic process 33.3333 5 no
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0032101 regulation of response to external stimulus 33.3333 4 no
GO:0043066 negative regulation of apoptotic process 33.3333 6 no
GO:0051094 positive regulation of developmental process 26.6667 4 no
GO:0051174 regulation of phosphorus metabolic process 26.6667 5 no
GO:0051247 positive regulation of protein metabolic process 26.6667 6 no
GO:0071363 cellular response to growth factor stimulus 26.6667 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 26.6667 6 no
GO:2000026 regulation of multicellular organismal development 26.6667 4 no
GO:0001818 negative regulation of cytokine production 26.6667 5 no
GO:0009890 negative regulation of biosynthetic process 26.6667 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 26.6667 6 no
GO:0010629 negative regulation of gene expression 26.6667 7 no
GO:0031327 negative regulation of cellular biosynthetic process 26.6667 6 no
GO:0051050 positive regulation of transport 26.6667 4 no
GO:0015031 protein transport 26.6667 4 no
GO:0007416 synapse assembly 26.6667 6 yes
GO:0033993 response to lipid 26.6667 4 yes
GO:0034329 cell junction assembly 26.6667 5 yes
GO:0034330 cell junction organization 26.6667 4 yes
GO:0046486 glycerolipid metabolic process 26.6667 4 yes
GO:0050808 synapse organization 26.6667 5 yes
GO:0001932 regulation of protein phosphorylation 26.6667 7 no
GO:0010648 negative regulation of cell communication 26.6667 5 no
GO:0019220 regulation of phosphate metabolic process 26.6667 6 no
GO:0023057 negative regulation of signaling 26.6667 4 no
GO:0031344 regulation of cell projection organization 26.6667 5 no
GO:0042325 regulation of phosphorylation 26.6667 7 no
GO:0006638 neutral lipid metabolic process 20.0000 4 yes
GO:0006639 acylglycerol metabolic process 20.0000 5 yes
GO:0006641 triglyceride metabolic process 20.0000 6 yes
GO:0006644 phospholipid metabolic process 20.0000 4 yes
GO:0006650 glycerophospholipid metabolic process 20.0000 5 yes
GO:0006796 phosphate-containing compound metabolic process 20.0000 4 yes
GO:0070542 response to fatty acid 20.0000 4 yes
GO:0006631 fatty acid metabolic process 13.3333 4 yes
GO:0006654 phosphatidic acid biosynthetic process 13.3333 6 yes
GO:0006662 glycerol ether metabolic process 13.3333 4 yes
GO:0007043 cell-cell junction assembly 13.3333 6 yes
GO:0008610 lipid biosynthetic process 13.3333 4 yes
GO:0008611 ether lipid biosynthetic process 13.3333 5 yes
GO:0008654 phospholipid biosynthetic process 13.3333 5 yes
GO:0019432 triglyceride biosynthetic process 13.3333 6 yes
GO:0019752 carboxylic acid metabolic process 13.3333 5 yes
GO:0030913 paranodal junction assembly 13.3333 4 yes
GO:0032787 monocarboxylic acid metabolic process 13.3333 6 yes
GO:0043436 oxoacid metabolic process 13.3333 4 yes
GO:0045017 glycerolipid biosynthetic process 13.3333 4 yes
GO:0045216 cell-cell junction organization 13.3333 5 yes
GO:0046460 neutral lipid biosynthetic process 13.3333 4 yes
GO:0046463 acylglycerol biosynthetic process 13.3333 5 yes
GO:0046473 phosphatidic acid metabolic process 13.3333 6 yes
GO:0046474 glycerophospholipid biosynthetic process 13.3333 5 yes
GO:0046485 ether lipid metabolic process 13.3333 4 yes
GO:0046504 glycerol ether biosynthetic process 13.3333 4 yes
GO:0061024 membrane organization 13.3333 4 yes
GO:0090407 organophosphate biosynthetic process 13.3333 4 yes
GO:0097384 cellular lipid biosynthetic process 13.3333 4 yes
GO:1901503 ether biosynthetic process 13.3333 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ADAS_HUMAN [view interactions] Low throughput no yes
ARRB1_HUMAN [view entry] [view interactions] High throughput yes yes
SLX4_HUMAN [view interactions] High throughput no yes
CTR1_HUMAN [view interactions] High throughput no no
C3AR_HUMAN [view interactions] High throughput no no
PRSR2_HUMAN [view interactions] High throughput no yes
DAAF8_HUMAN [view interactions] High throughput no no
PACC1_HUMAN [view interactions] High throughput no no
LYPD3_HUMAN [view interactions] High throughput no no
GRPR_HUMAN [view interactions] High throughput no no
C1QT2_HUMAN [view interactions] High throughput no yes
IL1R2_HUMAN [view interactions] High throughput no no
F131B_HUMAN [view interactions] High throughput no no
ENPP6_HUMAN [view entry] [view interactions] High throughput yes no
FANCE_HUMAN [view interactions] High throughput no yes
ODAD4_HUMAN [view interactions] High throughput no no
ZN544_HUMAN [view interactions] High throughput no yes
DCA11_HUMAN [view interactions] High throughput no yes
IFTAP_HUMAN [view interactions] High throughput no no
PEX14_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
HSC20_HUMAN [view interactions] High throughput no yes
PTPS_HUMAN [view interactions] High throughput no yes
GPR3_HUMAN [view interactions] High throughput no no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
CATA_HUMAN [view entry] [view interactions] High throughput yes no
FHI2B_HUMAN [view interactions] High throughput no yes
VDR_HUMAN [view interactions] High throughput no no
BARD1_HUMAN [view interactions] High throughput no yes
PEX5_HUMAN [view interactions] High throughput no yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
PMF1_HUMAN [view interactions] High throughput no no
S39A4_HUMAN [view interactions] High throughput no no
MINY2_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
WDTC1_HUMAN [view interactions] High throughput no yes
SG2A2_HUMAN [view interactions] High throughput no no
PVR_HUMAN [view interactions] High throughput no yes
HDA10_HUMAN [view interactions] High throughput no yes
LYPD4_HUMAN [view interactions] High throughput no no
ATX3_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
WWOX_HUMAN [view interactions] High throughput no yes
NINL_HUMAN [view interactions] High throughput no yes
CALL3_HUMAN [view interactions] High throughput no yes
HYPM_HUMAN [view interactions] High throughput no no
IFT20_HUMAN [view interactions] High throughput no yes
SAAL1_HUMAN [view interactions] High throughput no yes
NPTN_HUMAN [view entry] [view interactions] High throughput yes yes
AR2BP_HUMAN [view interactions] High throughput no yes
GPC3_HUMAN [view interactions] High throughput no no
APOA2_HUMAN [view interactions] High throughput no no
S10A9_HUMAN [view entry] [view interactions] High throughput yes no
GIP_HUMAN [view interactions] High throughput no no
HCST_HUMAN [view interactions] High throughput no no
GHRL_HUMAN [view entry] [view interactions] High throughput yes no
DLL1_HUMAN [view interactions] High throughput no no
TSN10_HUMAN [view interactions] High throughput no no
RU1C_HUMAN [view interactions] High throughput no yes
BNIP5_HUMAN [view interactions] High throughput no no
AT7L1_HUMAN [view interactions] High throughput no yes
CYB5B_HUMAN [view entry] [view interactions] High throughput yes yes
TGFA_HUMAN [view interactions] High throughput no yes
PAHX_HUMAN [view interactions] High throughput no yes
GP182_HUMAN [view interactions] High throughput no no
GALA_HUMAN [view interactions] High throughput no no
FFAR1_HUMAN [view interactions] High throughput no no
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
RBCC1_HUMAN [view interactions] High throughput no no
PLD6_HUMAN [view interactions] High throughput no yes
TLS1_HUMAN [view interactions] High throughput no yes
ATG5_HUMAN [view entry] [view interactions] High throughput yes no
CCNF_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
GNPAT_HUMAN [view entry] [view interactions] High throughput yes no
SAE2_HUMAN [view interactions] High throughput no yes
CSK_HUMAN [view interactions] High throughput no yes
HEBP1_HUMAN [view interactions] High throughput no yes
COIL_HUMAN [view interactions] High throughput no yes
CLPP_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes