Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CAN5_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Calcium-regulated non-lysosomal thiol-protease. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CAN5_HUMAN
GO:0019900 kinase binding 28.5714 4 no
GO:0019901 protein kinase binding 28.5714 5 no
GO:0045296 cadherin binding 28.5714 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in CAN5_HUMAN
GO:0048522 positive regulation of cellular process 57.1429 4 no
GO:0048523 negative regulation of cellular process 57.1429 4 no
GO:0051128 regulation of cellular component organization 57.1429 4 no
GO:0006996 organelle organization 42.8571 4 no
GO:0008104 protein localization 42.8571 4 no
GO:0022603 regulation of anatomical structure morphogenesis 42.8571 4 no
GO:0006508 proteolysis 28.5714 4 yes
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0001933 negative regulation of protein phosphorylation 28.5714 8 no
GO:0009057 macromolecule catabolic process 28.5714 4 no
GO:0009892 negative regulation of metabolic process 28.5714 4 no
GO:0009893 positive regulation of metabolic process 28.5714 4 no
GO:0010563 negative regulation of phosphorus metabolic process 28.5714 6 no
GO:0010604 positive regulation of macromolecule metabolic process 28.5714 5 no
GO:0010605 negative regulation of macromolecule metabolic process 28.5714 5 no
GO:0010639 negative regulation of organelle organization 28.5714 6 no
GO:0019220 regulation of phosphate metabolic process 28.5714 6 no
GO:0022607 cellular component assembly 28.5714 4 no
GO:0030163 protein catabolic process 28.5714 4 no
GO:0031323 regulation of cellular metabolic process 28.5714 4 no
GO:0031324 negative regulation of cellular metabolic process 28.5714 5 no
GO:0031325 positive regulation of cellular metabolic process 28.5714 5 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0031400 negative regulation of protein modification process 28.5714 7 no
GO:0031401 positive regulation of protein modification process 28.5714 7 no
GO:0032231 regulation of actin filament bundle assembly 28.5714 5 no
GO:0032232 negative regulation of actin filament bundle assembly 28.5714 6 no
GO:0032880 regulation of protein localization 28.5714 5 no
GO:0032956 regulation of actin cytoskeleton organization 28.5714 5 no
GO:0032970 regulation of actin filament-based process 28.5714 4 no
GO:0033043 regulation of organelle organization 28.5714 5 no
GO:0033673 negative regulation of kinase activity 28.5714 6 no
GO:0036211 protein modification process 28.5714 4 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0042326 negative regulation of phosphorylation 28.5714 8 no
GO:0042981 regulation of apoptotic process 28.5714 5 no
GO:0043066 negative regulation of apoptotic process 28.5714 6 no
GO:0043067 regulation of programmed cell death 28.5714 4 no
GO:0043069 negative regulation of programmed cell death 28.5714 5 no
GO:0043086 negative regulation of catalytic activity 28.5714 4 no
GO:0043412 macromolecule modification 28.5714 4 no
GO:0043549 regulation of kinase activity 28.5714 5 no
GO:0044087 regulation of cellular component biogenesis 28.5714 4 no
GO:0045936 negative regulation of phosphate metabolic process 28.5714 7 no
GO:0051094 positive regulation of developmental process 28.5714 4 no
GO:0051129 negative regulation of cellular component organization 28.5714 5 no
GO:0051174 regulation of phosphorus metabolic process 28.5714 5 no
GO:0051246 regulation of protein metabolic process 28.5714 5 no
GO:0051247 positive regulation of protein metabolic process 28.5714 6 no
GO:0051248 negative regulation of protein metabolic process 28.5714 6 no
GO:0051338 regulation of transferase activity 28.5714 4 no
GO:0051348 negative regulation of transferase activity 28.5714 5 no
GO:0051493 regulation of cytoskeleton organization 28.5714 6 no
GO:0051494 negative regulation of cytoskeleton organization 28.5714 7 no
GO:0060255 regulation of macromolecule metabolic process 28.5714 4 no
GO:0060341 regulation of cellular localization 28.5714 4 no
GO:0071310 cellular response to organic substance 28.5714 4 no
GO:0071702 organic substance transport 28.5714 4 no
GO:0071705 nitrogen compound transport 28.5714 4 no
GO:0080090 regulation of primary metabolic process 28.5714 4 no
GO:0110053 regulation of actin filament organization 28.5714 6 no
GO:1901565 organonitrogen compound catabolic process 28.5714 4 no
GO:1902903 regulation of supramolecular fiber organization 28.5714 5 no
GO:1902904 negative regulation of supramolecular fiber organization 28.5714 6 no
GO:1903828 negative regulation of protein localization 28.5714 5 no
GO:1903829 positive regulation of protein localization 28.5714 5 no
GO:0007010 cytoskeleton organization 28.5714 5 no
GO:0030334 regulation of cell migration 28.5714 5 no
GO:2000145 regulation of cell motility 28.5714 4 no
GO:0050807 regulation of synapse organization 28.5714 5 no
GO:0099175 regulation of postsynapse organization 28.5714 6 no
GO:0046903 secretion 28.5714 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ZO1_HUMAN [view entry] [view interactions] Low throughput yes no
MLH1_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
CD81_HUMAN [view interactions] High throughput no no
PHTF1_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
CAN3_HUMAN [view interactions] High throughput no no
FBX7_HUMAN [view interactions] High throughput no yes
AB17C_HUMAN [view entry] [view interactions] High throughput yes no
CAN10_HUMAN [view interactions] High throughput no yes
CAN12_HUMAN [view interactions] High throughput no no
CAN6_HUMAN [view interactions] High throughput no no
CP4F3_HUMAN [view interactions] High throughput no no
EXOC3_HUMAN [view entry] [view interactions] High throughput yes no
MP2K6_HUMAN [view interactions] High throughput no yes
NCF4_HUMAN [view interactions] High throughput no no
SCMC3_HUMAN [view interactions] High throughput no yes
STAP2_HUMAN [view interactions] High throughput no yes
ZER1_HUMAN [view interactions] High throughput no no