Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CYTC_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CYTC_HUMAN
GO:0004866 endopeptidase inhibitor activity 44.4444 5 yes
GO:0030414 peptidase inhibitor activity 44.4444 4 yes
GO:0061135 endopeptidase regulator activity 44.4444 4 yes
GO:0004869 cysteine-type endopeptidase inhibitor activity 33.3333 6 yes
GO:0002020 protease binding 22.2222 4 yes
GO:0000166 nucleotide binding 22.2222 4 no
GO:0005524 ATP binding 22.2222 5 no
GO:0017076 purine nucleotide binding 22.2222 5 no
GO:0030554 adenyl nucleotide binding 22.2222 6 no
GO:0032555 purine ribonucleotide binding 22.2222 4 no
GO:0032559 adenyl ribonucleotide binding 22.2222 5 no
GO:0035639 purine ribonucleoside triphosphate binding 22.2222 4 no
GO:0043168 anion binding 22.2222 4 no
GO:0003723 RNA binding 22.2222 4 no
GO:0043169 cation binding 22.2222 4 no
GO:0046872 metal ion binding 22.2222 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in CYTC_HUMAN
GO:0048523 negative regulation of cellular process 66.6667 4 yes
GO:0009892 negative regulation of metabolic process 55.5556 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 55.5556 5 yes
GO:0051128 regulation of cellular component organization 55.5556 4 yes
GO:0060255 regulation of macromolecule metabolic process 55.5556 4 yes
GO:0080090 regulation of primary metabolic process 55.5556 4 yes
GO:0051246 regulation of protein metabolic process 44.4444 5 yes
GO:0006796 phosphate-containing compound metabolic process 44.4444 4 no
GO:0043412 macromolecule modification 44.4444 4 no
GO:0048522 positive regulation of cellular process 44.4444 4 no
GO:0051049 regulation of transport 44.4444 4 no
GO:0071310 cellular response to organic substance 44.4444 4 no
GO:0009894 regulation of catabolic process 33.3333 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 33.3333 4 yes
GO:0043086 negative regulation of catalytic activity 33.3333 4 yes
GO:0051093 negative regulation of developmental process 33.3333 4 yes
GO:0051129 negative regulation of cellular component organization 33.3333 5 yes
GO:0051248 negative regulation of protein metabolic process 33.3333 6 yes
GO:0051336 regulation of hydrolase activity 33.3333 4 yes
GO:0097435 supramolecular fiber organization 33.3333 4 yes
GO:0006468 protein phosphorylation 33.3333 5 no
GO:0009966 regulation of signal transduction 33.3333 4 no
GO:0010243 response to organonitrogen compound 33.3333 4 no
GO:0010646 regulation of cell communication 33.3333 4 no
GO:0016310 phosphorylation 33.3333 5 no
GO:0031323 regulation of cellular metabolic process 33.3333 4 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0032880 regulation of protein localization 33.3333 5 no
GO:0034762 regulation of transmembrane transport 33.3333 4 no
GO:0036211 protein modification process 33.3333 4 no
GO:0042127 regulation of cell population proliferation 33.3333 4 no
GO:0060341 regulation of cellular localization 33.3333 4 no
GO:0071417 cellular response to organonitrogen compound 33.3333 4 no
GO:1901699 cellular response to nitrogen compound 33.3333 4 no
GO:1901701 cellular response to oxygen-containing compound 33.3333 4 no
GO:0016070 RNA metabolic process 33.3333 5 no
GO:0090304 nucleic acid metabolic process 33.3333 4 no
GO:0009895 negative regulation of catabolic process 22.2222 5 yes
GO:0010466 negative regulation of peptidase activity 22.2222 6 yes
GO:0010710 regulation of collagen catabolic process 22.2222 5 yes
GO:0010711 negative regulation of collagen catabolic process 22.2222 6 yes
GO:0010712 regulation of collagen metabolic process 22.2222 4 yes
GO:0010713 negative regulation of collagen metabolic process 22.2222 5 yes
GO:0010715 regulation of extracellular matrix disassembly 22.2222 6 yes
GO:0010716 negative regulation of extracellular matrix disassembly 22.2222 7 yes
GO:0030162 regulation of proteolysis 22.2222 6 yes
GO:0034103 regulation of tissue remodeling 22.2222 4 yes
GO:0034104 negative regulation of tissue remodeling 22.2222 5 yes
GO:0042176 regulation of protein catabolic process 22.2222 5 yes
GO:0042177 negative regulation of protein catabolic process 22.2222 6 yes
GO:0045861 negative regulation of proteolysis 22.2222 7 yes
GO:0051241 negative regulation of multicellular organismal process 22.2222 4 yes
GO:0051346 negative regulation of hydrolase activity 22.2222 5 yes
GO:0052547 regulation of peptidase activity 22.2222 5 yes
GO:0060310 regulation of elastin catabolic process 22.2222 6 yes
GO:0060311 negative regulation of elastin catabolic process 22.2222 7 yes
GO:0060312 regulation of blood vessel remodeling 22.2222 5 yes
GO:0060313 negative regulation of blood vessel remodeling 22.2222 5 yes
GO:1903018 regulation of glycoprotein metabolic process 22.2222 6 yes
GO:1903019 negative regulation of glycoprotein metabolic process 22.2222 7 yes
GO:1903053 regulation of extracellular matrix organization 22.2222 5 yes
GO:1903054 negative regulation of extracellular matrix organization 22.2222 6 yes
GO:0001932 regulation of protein phosphorylation 22.2222 7 no
GO:0001934 positive regulation of protein phosphorylation 22.2222 8 no
GO:0002684 positive regulation of immune system process 22.2222 4 no
GO:0006996 organelle organization 22.2222 4 no
GO:0008284 positive regulation of cell population proliferation 22.2222 5 no
GO:0009893 positive regulation of metabolic process 22.2222 4 no
GO:0009967 positive regulation of signal transduction 22.2222 5 no
GO:0009968 negative regulation of signal transduction 22.2222 5 no
GO:0010562 positive regulation of phosphorus metabolic process 22.2222 6 no
GO:0010604 positive regulation of macromolecule metabolic process 22.2222 5 no
GO:0010647 positive regulation of cell communication 22.2222 5 no
GO:0010648 negative regulation of cell communication 22.2222 5 no
GO:0010959 regulation of metal ion transport 22.2222 6 no
GO:0019220 regulation of phosphate metabolic process 22.2222 6 no
GO:0019722 calcium-mediated signaling 22.2222 5 no
GO:0023056 positive regulation of signaling 22.2222 4 no
GO:0023057 negative regulation of signaling 22.2222 4 no
GO:0030334 regulation of cell migration 22.2222 5 no
GO:0030335 positive regulation of cell migration 22.2222 6 no
GO:0031325 positive regulation of cellular metabolic process 22.2222 5 no
GO:0031347 regulation of defense response 22.2222 5 no
GO:0031399 regulation of protein modification process 22.2222 6 no
GO:0031401 positive regulation of protein modification process 22.2222 7 no
GO:0032101 regulation of response to external stimulus 22.2222 4 no
GO:0032870 cellular response to hormone stimulus 22.2222 4 no
GO:0034765 regulation of monoatomic ion transmembrane transport 22.2222 5 no
GO:0040017 positive regulation of locomotion 22.2222 4 no
GO:0042325 regulation of phosphorylation 22.2222 7 no
GO:0042327 positive regulation of phosphorylation 22.2222 8 no
GO:0042981 regulation of apoptotic process 22.2222 5 no
GO:0043066 negative regulation of apoptotic process 22.2222 6 no
GO:0043067 regulation of programmed cell death 22.2222 4 no
GO:0043069 negative regulation of programmed cell death 22.2222 5 no
GO:0043269 regulation of monoatomic ion transport 22.2222 5 no
GO:0043549 regulation of kinase activity 22.2222 5 no
GO:0045859 regulation of protein kinase activity 22.2222 6 no
GO:0045937 positive regulation of phosphate metabolic process 22.2222 7 no
GO:0048584 positive regulation of response to stimulus 22.2222 4 no
GO:0048585 negative regulation of response to stimulus 22.2222 4 no
GO:0051174 regulation of phosphorus metabolic process 22.2222 5 no
GO:0051240 positive regulation of multicellular organismal process 22.2222 4 no
GO:0051247 positive regulation of protein metabolic process 22.2222 6 no
GO:0051338 regulation of transferase activity 22.2222 4 no
GO:0051924 regulation of calcium ion transport 22.2222 7 no
GO:0060627 regulation of vesicle-mediated transport 22.2222 4 no
GO:0080134 regulation of response to stress 22.2222 4 no
GO:0141124 intracellular signaling cassette 22.2222 4 no
GO:1902531 regulation of intracellular signal transduction 22.2222 5 no
GO:1902533 positive regulation of intracellular signal transduction 22.2222 6 no
GO:1903169 regulation of calcium ion transmembrane transport 22.2222 7 no
GO:1903829 positive regulation of protein localization 22.2222 5 no
GO:1904062 regulation of monoatomic cation transmembrane transport 22.2222 6 no
GO:1905475 regulation of protein localization to membrane 22.2222 6 no
GO:1905477 positive regulation of protein localization to membrane 22.2222 6 no
GO:2000145 regulation of cell motility 22.2222 4 no
GO:2000147 positive regulation of cell motility 22.2222 5 no
GO:0006396 RNA processing 22.2222 6 no
GO:0008202 steroid metabolic process 22.2222 4 no
GO:0022607 cellular component assembly 22.2222 4 no
GO:0043933 protein-containing complex organization 22.2222 4 no
GO:1901565 organonitrogen compound catabolic process 22.2222 4 no
GO:0006915 apoptotic process 22.2222 4 no
GO:0010564 regulation of cell cycle process 22.2222 5 no
GO:0051726 regulation of cell cycle 22.2222 4 no
GO:0014070 response to organic cyclic compound 22.2222 4 no
GO:0022898 regulation of transmembrane transporter activity 22.2222 4 no
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 22.2222 5 no
GO:0070201 regulation of establishment of protein localization 22.2222 6 no
GO:0006355 regulation of DNA-templated transcription 22.2222 7 no
GO:0008088 axo-dendritic transport 22.2222 5 no
GO:0009889 regulation of biosynthetic process 22.2222 4 no
GO:0009890 negative regulation of biosynthetic process 22.2222 5 no
GO:0010468 regulation of gene expression 22.2222 6 no
GO:0010556 regulation of macromolecule biosynthetic process 22.2222 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 22.2222 6 no
GO:0010970 transport along microtubule 22.2222 4 no
GO:0016071 mRNA metabolic process 22.2222 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 22.2222 5 no
GO:0030705 cytoskeleton-dependent intracellular transport 22.2222 4 no
GO:0031326 regulation of cellular biosynthetic process 22.2222 5 no
GO:0031327 negative regulation of cellular biosynthetic process 22.2222 6 no
GO:0044087 regulation of cellular component biogenesis 22.2222 4 no
GO:0051252 regulation of RNA metabolic process 22.2222 5 no
GO:0099111 microtubule-based transport 22.2222 4 no
GO:1902903 regulation of supramolecular fiber organization 22.2222 5 no
GO:2001141 regulation of RNA biosynthetic process 22.2222 6 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CYTC_HUMAN [view entry] [view interactions] Low throughput yes yes
RN115_HUMAN [view interactions] Low throughput no yes
CATB_HUMAN [view interactions] Low throughput no yes
CO4A_HUMAN [view interactions] Low throughput no no
CYTB_HUMAN [view interactions] Low throughput no no
PDPK1_HUMAN [view entry] [view interactions] High throughput yes yes
ATX1_HUMAN [view interactions] High throughput no yes
DDX31_HUMAN [view interactions] High throughput no no
SAP_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
ALBU_HUMAN [view interactions] High throughput no no
TX101_HUMAN [view interactions] High throughput no no
FA20C_HUMAN [view interactions] High throughput no no
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
CATH_HUMAN [view interactions] High throughput no no
CATL2_HUMAN [view interactions] High throughput no yes
SAPC2_HUMAN [view interactions] High throughput no no
CATC_HUMAN [view interactions] High throughput no yes
ZER1_HUMAN [view interactions] High throughput no no
LCAP_HUMAN [view interactions] High throughput no yes
CATO_HUMAN [view interactions] High throughput no yes
MAOX_HUMAN [view interactions] High throughput no yes
CATL1_HUMAN [view interactions] High throughput no yes
HPCA_HUMAN [view entry] [view interactions] High throughput yes yes
LGMN_HUMAN [view interactions] High throughput no yes
BIRC6_HUMAN [view entry] [view interactions] High throughput yes yes
ZNG1A_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
ASPG_HUMAN [view interactions] High throughput no yes
CATS_HUMAN [view interactions] High throughput no no
CO4B_HUMAN [view interactions] High throughput no no
CATD_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes