Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CYTC_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CYTC_HUMAN
GO:0004866 endopeptidase inhibitor activity 57.1429 5 yes
GO:0030414 peptidase inhibitor activity 57.1429 4 yes
GO:0061135 endopeptidase regulator activity 57.1429 4 yes
GO:0004869 cysteine-type endopeptidase inhibitor activity 42.8571 6 yes
GO:0001540 amyloid-beta binding 28.5714 4 yes
GO:0002020 protease binding 28.5714 4 yes
GO:0046872 metal ion binding 28.5714 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in CYTC_HUMAN
GO:0048523 negative regulation of cellular process 85.7143 4 yes
GO:0009892 negative regulation of metabolic process 71.4286 4 yes
GO:0031323 regulation of cellular metabolic process 71.4286 4 yes
GO:0031324 negative regulation of cellular metabolic process 71.4286 5 yes
GO:0051171 regulation of nitrogen compound metabolic process 71.4286 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 71.4286 5 yes
GO:0051336 regulation of hydrolase activity 71.4286 4 yes
GO:0080090 regulation of primary metabolic process 71.4286 4 yes
GO:0043412 macromolecule modification 57.1429 4 no
GO:0048522 positive regulation of cellular process 57.1429 4 no
GO:0010605 negative regulation of macromolecule metabolic process 57.1429 5 yes
GO:0043086 negative regulation of catalytic activity 57.1429 4 yes
GO:0051128 regulation of cellular component organization 57.1429 4 yes
GO:0051246 regulation of protein metabolic process 57.1429 5 yes
GO:0060255 regulation of macromolecule metabolic process 57.1429 4 yes
GO:0016310 phosphorylation 42.8571 5 no
GO:0019220 regulation of phosphate metabolic process 42.8571 6 no
GO:0019722 calcium-mediated signaling 42.8571 5 no
GO:0019932 second-messenger-mediated signaling 42.8571 4 no
GO:0023057 negative regulation of signaling 42.8571 4 no
GO:0032880 regulation of protein localization 42.8571 5 no
GO:0034762 regulation of transmembrane transport 42.8571 4 no
GO:0034765 regulation of ion transmembrane transport 42.8571 5 no
GO:0036211 protein modification process 42.8571 4 no
GO:0042127 regulation of cell population proliferation 42.8571 4 no
GO:0042981 regulation of apoptotic process 42.8571 6 no
GO:0043067 regulation of programmed cell death 42.8571 5 no
GO:0043085 positive regulation of catalytic activity 42.8571 4 no
GO:0043269 regulation of ion transport 42.8571 5 no
GO:0048585 negative regulation of response to stimulus 42.8571 4 no
GO:0051049 regulation of transport 42.8571 4 no
GO:0051050 positive regulation of transport 42.8571 4 no
GO:0051174 regulation of phosphorus metabolic process 42.8571 5 no
GO:0051345 positive regulation of hydrolase activity 42.8571 5 no
GO:0060341 regulation of cellular localization 42.8571 4 no
GO:0060548 negative regulation of cell death 42.8571 5 no
GO:0060627 regulation of vesicle-mediated transport 42.8571 4 no
GO:1903829 positive regulation of protein localization 42.8571 5 no
GO:1904062 regulation of cation transmembrane transport 42.8571 6 no
GO:0009894 regulation of catabolic process 42.8571 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 42.8571 4 yes
GO:0030162 regulation of proteolysis 42.8571 6 yes
GO:0031329 regulation of cellular catabolic process 42.8571 5 yes
GO:0042176 regulation of protein catabolic process 42.8571 5 yes
GO:0051093 negative regulation of developmental process 42.8571 4 yes
GO:0051129 negative regulation of cellular component organization 42.8571 5 yes
GO:0051241 negative regulation of multicellular organismal process 42.8571 4 yes
GO:0051248 negative regulation of protein metabolic process 42.8571 6 yes
GO:0052547 regulation of peptidase activity 42.8571 5 yes
GO:0097435 supramolecular fiber organization 42.8571 4 yes
GO:0006468 protein phosphorylation 42.8571 5 no
GO:0006796 phosphate-containing compound metabolic process 42.8571 4 no
GO:0009966 regulation of signal transduction 42.8571 4 no
GO:0009968 negative regulation of signal transduction 42.8571 5 no
GO:0010243 response to organonitrogen compound 42.8571 4 no
GO:0010646 regulation of cell communication 42.8571 4 no
GO:0010648 negative regulation of cell communication 42.8571 5 no
GO:0010941 regulation of cell death 42.8571 4 no
GO:0030334 regulation of cell migration 28.5714 5 no
GO:0030335 positive regulation of cell migration 28.5714 6 no
GO:0031325 positive regulation of cellular metabolic process 28.5714 5 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0031401 positive regulation of protein modification process 28.5714 7 no
GO:0033674 positive regulation of kinase activity 28.5714 6 no
GO:0034121 regulation of toll-like receptor signaling pathway 28.5714 6 no
GO:0040017 positive regulation of locomotion 28.5714 4 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0042327 positive regulation of phosphorylation 28.5714 8 no
GO:0043066 negative regulation of apoptotic process 28.5714 7 no
GO:0043069 negative regulation of programmed cell death 28.5714 6 no
GO:0043549 regulation of kinase activity 28.5714 5 no
GO:0045859 regulation of protein kinase activity 28.5714 6 no
GO:0045860 positive regulation of protein kinase activity 28.5714 7 no
GO:0045936 negative regulation of phosphate metabolic process 28.5714 7 no
GO:0045937 positive regulation of phosphate metabolic process 28.5714 7 no
GO:0050776 regulation of immune response 28.5714 4 no
GO:0050865 regulation of cell activation 28.5714 4 no
GO:0051094 positive regulation of developmental process 28.5714 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 28.5714 5 no
GO:0051240 positive regulation of multicellular organismal process 28.5714 4 no
GO:0051247 positive regulation of protein metabolic process 28.5714 6 no
GO:0051338 regulation of transferase activity 28.5714 4 no
GO:0051347 positive regulation of transferase activity 28.5714 5 no
GO:0051924 regulation of calcium ion transport 28.5714 7 no
GO:0060191 regulation of lipase activity 28.5714 5 no
GO:0060193 positive regulation of lipase activity 28.5714 6 no
GO:0062207 regulation of pattern recognition receptor signaling pathway 28.5714 5 no
GO:0070848 response to growth factor 28.5714 4 no
GO:0071310 cellular response to organic substance 28.5714 4 no
GO:0071363 cellular response to growth factor stimulus 28.5714 5 no
GO:0071417 cellular response to organonitrogen compound 28.5714 4 no
GO:1901652 response to peptide 28.5714 4 no
GO:1901653 cellular response to peptide 28.5714 5 no
GO:1901699 cellular response to nitrogen compound 28.5714 4 no
GO:1901701 cellular response to oxygen-containing compound 28.5714 4 no
GO:1902531 regulation of intracellular signal transduction 28.5714 5 no
GO:1903169 regulation of calcium ion transmembrane transport 28.5714 7 no
GO:1905475 regulation of protein localization to membrane 28.5714 6 no
GO:1905477 positive regulation of protein localization to membrane 28.5714 6 no
GO:2000145 regulation of cell motility 28.5714 4 no
GO:2000147 positive regulation of cell motility 28.5714 5 no
GO:0006396 RNA processing 28.5714 6 no
GO:0008202 steroid metabolic process 28.5714 4 no
GO:0016070 RNA metabolic process 28.5714 5 no
GO:0022607 cellular component assembly 28.5714 4 no
GO:0031123 RNA 3-end processing 28.5714 7 no
GO:0043933 protein-containing complex organization 28.5714 4 no
GO:0051259 protein complex oligomerization 28.5714 6 no
GO:0051260 protein homooligomerization 28.5714 7 no
GO:0051262 protein tetramerization 28.5714 7 no
GO:0065003 protein-containing complex assembly 28.5714 5 no
GO:0090304 nucleic acid metabolic process 28.5714 4 no
GO:0006915 apoptotic process 28.5714 4 no
GO:0010564 regulation of cell cycle process 28.5714 5 no
GO:0051726 regulation of cell cycle 28.5714 4 no
GO:0002090 regulation of receptor internalization 28.5714 7 no
GO:0006140 regulation of nucleotide metabolic process 28.5714 5 no
GO:0009889 regulation of biosynthetic process 28.5714 4 no
GO:0009890 negative regulation of biosynthetic process 28.5714 5 no
GO:0010038 response to metal ion 28.5714 4 no
GO:0014070 response to organic cyclic compound 28.5714 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.5714 5 no
GO:0022898 regulation of transmembrane transporter activity 28.5714 4 no
GO:0030100 regulation of endocytosis 28.5714 5 no
GO:0031326 regulation of cellular biosynthetic process 28.5714 5 no
GO:0031327 negative regulation of cellular biosynthetic process 28.5714 6 no
GO:0032412 regulation of ion transmembrane transporter activity 28.5714 5 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 28.5714 6 no
GO:0048259 regulation of receptor-mediated endocytosis 28.5714 6 no
GO:0051222 positive regulation of protein transport 28.5714 5 no
GO:0051223 regulation of protein transport 28.5714 5 no
GO:0062012 regulation of small molecule metabolic process 28.5714 4 no
GO:0070201 regulation of establishment of protein localization 28.5714 6 no
GO:0071241 cellular response to inorganic substance 28.5714 4 no
GO:0071248 cellular response to metal ion 28.5714 5 no
GO:1900542 regulation of purine nucleotide metabolic process 28.5714 6 no
GO:1904951 positive regulation of establishment of protein localization 28.5714 6 no
GO:2001257 regulation of cation channel activity 28.5714 6 no
GO:0009895 negative regulation of catabolic process 28.5714 5 yes
GO:0010466 negative regulation of peptidase activity 28.5714 6 yes
GO:0010710 regulation of collagen catabolic process 28.5714 5 yes
GO:0010711 negative regulation of collagen catabolic process 28.5714 6 yes
GO:0010712 regulation of collagen metabolic process 28.5714 4 yes
GO:0010713 negative regulation of collagen metabolic process 28.5714 5 yes
GO:0010715 regulation of extracellular matrix disassembly 28.5714 6 yes
GO:0010716 negative regulation of extracellular matrix disassembly 28.5714 7 yes
GO:0031330 negative regulation of cellular catabolic process 28.5714 6 yes
GO:0034103 regulation of tissue remodeling 28.5714 4 yes
GO:0034104 negative regulation of tissue remodeling 28.5714 5 yes
GO:0042177 negative regulation of protein catabolic process 28.5714 6 yes
GO:0045861 negative regulation of proteolysis 28.5714 7 yes
GO:0051346 negative regulation of hydrolase activity 28.5714 5 yes
GO:0060310 regulation of elastin catabolic process 28.5714 6 yes
GO:0060311 negative regulation of elastin catabolic process 28.5714 7 yes
GO:0060312 regulation of blood vessel remodeling 28.5714 5 yes
GO:0060313 negative regulation of blood vessel remodeling 28.5714 5 yes
GO:1903018 regulation of glycoprotein metabolic process 28.5714 5 yes
GO:1903019 negative regulation of glycoprotein metabolic process 28.5714 6 yes
GO:1903053 regulation of extracellular matrix organization 28.5714 5 yes
GO:1903054 negative regulation of extracellular matrix organization 28.5714 6 yes
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0001934 positive regulation of protein phosphorylation 28.5714 8 no
GO:0002684 positive regulation of immune system process 28.5714 4 no
GO:0006996 organelle organization 28.5714 4 no
GO:0008284 positive regulation of cell population proliferation 28.5714 5 no
GO:0009893 positive regulation of metabolic process 28.5714 4 no
GO:0010517 regulation of phospholipase activity 28.5714 6 no
GO:0010518 positive regulation of phospholipase activity 28.5714 7 no
GO:0010562 positive regulation of phosphorus metabolic process 28.5714 6 no
GO:0010563 negative regulation of phosphorus metabolic process 28.5714 6 no
GO:0010604 positive regulation of macromolecule metabolic process 28.5714 5 no
GO:0010959 regulation of metal ion transport 28.5714 6 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CYTC_HUMAN [view entry] [view interactions] Low throughput yes yes
RN115_HUMAN [view interactions] Low throughput no yes
CATB_HUMAN [view interactions] Low throughput no yes
CO4A_HUMAN [view interactions] Low throughput no no
CYTB_HUMAN [view interactions] Low throughput no no
PDPK1_HUMAN [view entry] [view interactions] High throughput yes yes
ATX1_HUMAN [view interactions] High throughput no yes
DDX31_HUMAN [view interactions] High throughput no no
SAP_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
ALBU_HUMAN [view interactions] High throughput no no
TX101_HUMAN [view interactions] High throughput no no
FA20C_HUMAN [view interactions] High throughput no no
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
CATH_HUMAN [view interactions] High throughput no no
CATL2_HUMAN [view interactions] High throughput no yes
SAPC2_HUMAN [view interactions] High throughput no no
CATC_HUMAN [view interactions] High throughput no yes
ZER1_HUMAN [view interactions] High throughput no no
LCAP_HUMAN [view interactions] High throughput no yes
CATO_HUMAN [view interactions] High throughput no yes
MAOX_HUMAN [view interactions] High throughput no yes
CATL1_HUMAN [view interactions] High throughput no yes
HPCA_HUMAN [view entry] [view interactions] High throughput yes yes
LGMN_HUMAN [view interactions] High throughput no yes
BIRC6_HUMAN [view entry] [view interactions] High throughput yes yes
CBWD1_HUMAN [view interactions] High throughput no yes
ASPG_HUMAN [view interactions] High throughput no yes
CATS_HUMAN [view interactions] High throughput no no
CO4B_HUMAN [view interactions] High throughput no no
CATD_HUMAN [view interactions] High throughput no yes
ADIPO_HUMAN [view interactions] Computational no no
CRP_HUMAN [view interactions] Computational no no
HAVR1_HUMAN [view interactions] Computational no yes
SAA1_HUMAN [view interactions] Computational no no